Page last updated: 2024-08-22

tranylcypromine and warfarin

tranylcypromine has been researched along with warfarin in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's2 (28.57)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Adebesin, AM; Falck, JR; Fischer, R; Konkel, A; Lossie, J; Paudyal, MP; Puli, N; Schunck, WH; Vijaykumar, J; Wesser, T; Westphal, C; Zhu, C1
Kunze, KL; Rettie, AE; Storch, E; Trager, WF; Wienkers, LC; Wurden, CJ1
Gross, G; Lehmann, H; Löscher, W; Teschendorf, HJ; Traut, M1
Juvonen, R; Pelkonen, O; Taavitsainen, P1
Scott, EE; Stephens, ES; Walsh, AA1

Other Studies

7 other study(ies) available for tranylcypromine and warfarin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Development of Robust 17(
    Journal of medicinal chemistry, 2019, 11-27, Volume: 62, Issue:22

    Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Arachidonic Acids; Dose-Response Relationship, Drug; Drug Stability; Epoxide Hydrolases; Esterification; Hepatocytes; Humans; Male; Mice; Microsomes, Liver; Myocardial Infarction; Myocytes, Cardiac; Rats, Sprague-Dawley; Rats, Wistar

2019
Formation of (R)-8-hydroxywarfarin in human liver microsomes. A new metabolic marker for the (S)-mephenytoin hydroxylase, P4502C19.
    Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:5

    Topics: Aryl Hydrocarbon Hydroxylases; Biomarkers; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fluconazole; Humans; Hydroxylation; Kinetics; Mephenytoin; Microsomes, Liver; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; Theophylline; Tranylcypromine; Warfarin

1996
Inhibition of monoamine oxidase type A, but not type B, is an effective means of inducing anticonvulsant activity in the kindling model of epilepsy.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:3

    Topics: Animals; Anticonvulsants; Brain; Coumarins; Electric Stimulation; Epilepsy, Temporal Lobe; Female; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Rats; Rats, Wistar; Selegiline; Tranylcypromine

1999
In vitro inhibition of cytochrome P450 enzymes in human liver microsomes by a potent CYP2A6 inhibitor, trans-2-phenylcyclopropylamine (tranylcypromine), and its nonamine analog, cyclopropylbenzene.
    Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:3

    Topics: Aryl Hydrocarbon Hydroxylases; Benzene Derivatives; Binding Sites; Chlorzoxazone; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Inhibitory Concentration 50; Isoenzymes; Kinetics; Methoxsalen; Microsomes, Liver; Mixed Function Oxygenases; Molecular Structure; Monoterpenes; Spectrophotometry; Terpenes; Tranylcypromine

2001
Evaluation of inhibition selectivity for human cytochrome P450 2A enzymes.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:9

    Topics: Aryl Hydrocarbon Hydroxylases; Binding, Competitive; Catalysis; Coumarins; Cytochrome P-450 CYP2A6; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Hydroxylation; Ligands; Models, Biological; Molecular Structure; Monoterpenes; Nitrophenols; Protein Binding; Recombinant Proteins; Substrate Specificity; Tranylcypromine

2012