tranylcypromine has been researched along with tretinoin in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Biermann, K; Gillis, A; Looijenga, LH; Nettersheim, D; Schorle, H | 1 |
| Burnett, A; Casero, RA; Chen, WC; Dick, JE; Dugas, M; Göllner, S; Hebestreit, K; Howell, L; Jin, L; Klein, HU; Marton, L; Mills, K; Minden, MD; Müller-Tidow, C; Petrie, K; Popescu, AC; Schenk, T; Wang, JC; Woster, P; Zelent, A | 1 |
| DeSimone, J; Ibanez, V; Jagadeeswaran, R; Kouznetsova, T; Lavelle, D; Rivers, A; Ruiz, MA; Vaitkus, K | 1 |
| Goh, TW; Hin-Fai Yam, G; Mehta, JS; Setiawan, M; Tan, XW | 1 |
| Besenbeck, B; Binder, M; Bornhäuser, M; Burhenne, J; Dugas, M; Foerster, KI; Göllner, S; Göthert, JR; Haefeli, WE; Lenz, G; Mikesch, JH; Müller, LP; Müller-Tidow, C; Mundmann, P; Noppeney, R; Pabst, C; Platzbecker, U; Röllig, C; Schlenk, RF; Schliemann, C; Serve, H; Wass, M; Wermke, M | 1 |
| Bradley, TJ; Chen, C; Cimmino, L; Dinh, Y; Kwon, D; Morey, L; Perez, A; Santos, HGD; Shiekhattar, R; Swords, RT; Tayari, MM; Thomassen, A; Watts, JM; Zelent, A | 1 |
2 trial(s) available for tranylcypromine and tretinoin
| Article | Year |
|---|---|
A proof of concept phase I/II pilot trial of LSD1 inhibition by tranylcypromine combined with ATRA in refractory/relapsed AML patients not eligible for intensive therapy.
Topics: Adult; Aged; Antidepressive Agents; Antineoplastic Agents; Arabidopsis Proteins; DNA-Binding Proteins; Drug Resistance, Neoplasm; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Proof of Concept Study; Prospective Studies; Salvage Therapy; Survival Rate; Transcription Factors; Tranylcypromine; Tretinoin; Young Adult | 2021 |
Clinical Responsiveness to All-trans Retinoic Acid Is Potentiated by LSD1 Inhibition and Associated with a Quiescent Transcriptome in Myeloid Malignancies.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Female; Gene Expression Regulation, Leukemic; Histone Demethylases; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Transcriptome; Tranylcypromine; Tretinoin | 2021 |
6 other study(ies) available for tranylcypromine and tretinoin
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
The seminoma cell line TCam-2 is sensitive to HDAC inhibitor depsipeptide but tolerates various other chemotherapeutic drugs and loss of NANOG expression.
Topics: Apoptosis; Azacitidine; Cell Differentiation; Cell Line, Tumor; Decitabine; Depsipeptides; Down-Regulation; Drug Resistance, Neoplasm; Endoderm; Gene Knockdown Techniques; Histone Deacetylase Inhibitors; Histone Deacetylases; Homeodomain Proteins; Humans; Male; Nanog Homeobox Protein; Octamer Transcription Factor-3; Seminoma; SOXF Transcription Factors; Testicular Neoplasms; Transcription Factor AP-2; Tranylcypromine; Tretinoin; Up-Regulation | 2011 |
Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia.
Topics: Animals; Antigens, CD34; Apoptosis; CD11b Antigen; Cell Differentiation; Cells, Cultured; Cytokines; Disease Models, Animal; Drug Interactions; Enzyme Inhibitors; Female; Flow Cytometry; Gene Expression Regulation; Histone Demethylases; Humans; Leukemia, Myeloid, Acute; Lysine; Mice; Mice, Inbred NOD; Mice, SCID; RNA, Small Interfering; Stem Cell Factor; Time Factors; Transplants; Tranylcypromine; Tretinoin | 2012 |
RN-1, a potent and selective lysine-specific demethylase 1 inhibitor, increases γ-globin expression, F reticulocytes, and F cells in a sickle cell disease mouse model.
Topics: Anemia, Sickle Cell; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Erythroid Precursor Cells; Erythropoiesis; Fetal Hemoglobin; gamma-Globins; Gene Expression Regulation; Hematopoietic Stem Cells; Histone Demethylases; Histones; Humans; Hydroxyurea; Methylation; Mice; Mice, Transgenic; Papio; Protein Processing, Post-Translational; Reticulocytes; Transgenes; Tranylcypromine; Tretinoin; U937 Cells | 2015 |
Inhibiting glycogen synthase kinase-3 and transforming growth factor-β signaling to promote epithelial transition of human adipose mesenchymal stem cells.
Topics: Adipocytes; Adipose Tissue; Antigens, CD; Cadherins; Cell Movement; Enzyme Inhibitors; Epithelial Cell Adhesion Molecule; Epithelial-Mesenchymal Transition; Gene Expression Regulation; Glycogen Synthase Kinase 3; Humans; Integrin alpha5; Mesenchymal Stem Cells; Occludin; Primary Cell Culture; Pyrazoles; Pyridines; Pyrimidines; Snail Family Transcription Factors; Thiosemicarbazones; Transforming Growth Factor beta1; Tranylcypromine; Tretinoin; Valproic Acid; Vimentin; Xenopus Proteins; Zinc Finger E-box-Binding Homeobox 1; Zonula Occludens-1 Protein | 2017 |