Page last updated: 2024-08-22

tranylcypromine and selegiline

tranylcypromine has been researched along with selegiline in 43 studies

Research

Studies (43)

Timeframe	Studies, this research(%)	All Research%
pre-1990	24 (55.81)	18.7374
1990's	8 (18.60)	18.2507
2000's	8 (18.60)	29.6817
2010's	2 (4.65)	24.3611
2020's	1 (2.33)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Achee, FM; Gabay, S	1
Felner, AE; Waldmeier, PC	1
Boulton, AA; Philips, SR	1
Jefferson, JW	1
Nag, M; Nandi, N	1
Riederer, P; Youdim, MB	1
Marsden, CA; Martin, KF; Palfreyman, MG; Sleight, AJ	1
Fagervall, I; Ross, SB	1
Finberg, JP; Tal, A	1
Cohen, RM; Garrick, NA; Murphy, DL; Sunderland, T; Tamarkin, L	1
Linet, LS	1
Eisenhofer, G; Goldstein, DS; Keiser, HR; Kopin, IJ; Murphy, DL; Stull, R; Sunderland, T	1
Cohen, RM; Mueller, EA; Murphy, DL; Newhouse, PA; Sunderland, T; Tariot, PN	1
Frederickson, E; Palmer, R; Pi, E; Simpson, GM; Sloane, RB; White, K	1
Donnelly, M; Ismond, D; Rapoport, JL; Zametkin, A	1
Colpaert, FC; Janssen, PA; Niemegeers, CJ	1
Birkmayer, W; Danielczyk, W; Jellinger, K; Koppel, H; Reynolds, GP; Riederer, P; Seemann, D; Ulm, G	1
Möhrke, W; Mutschler, E	1
Dènes, B; Greeff, K; Tawfik, H	2
Reynolds, GP; Riederer, P	1
Benedetti, MS; Dostert, P; Guffroy, C; Tipton, KF	1
Ashkenazi, R; Finberg, JP; Youdim, MB	1
Lenzen, S; Nahrstedt, H; Panten, U	1
Ancher, JF; Benedetti, MS; Sontag, N	1
Rausch, WD; Reynolds, GP; Riederer, P	1
Artigas, F; Celada, P	2
Cabanillas, AM; Coleoni, AH; Costamagna, ME; Masini-Repiso, AM; Pellizas, C	1
Baker, GB; Todd, KG	1
Chouinard, S; Fahn, S	1
Gross, G; Lehmann, H; Löscher, W; Teschendorf, HJ; Traut, M	1
Gorodetsky, E; Gross, A; Wang, RH; Weinreb, O; Weinstock, M; Youdim, MB	1
Carey, GJ; Gold, LH; Nielsen, DM	1
Gorman, JM	1
Masand, PS; Pae, CU; Patkar, AA	1
Azzaro, AJ; Blob, LF; Campbell, BJ; Kemper, EM; Oren, DA; Sharoky, M; Vandenberg, CM	1
Baker, GB; Sowa, B; Todd, KG	1
Bhutani, MK; Bishnoi, M; Kulkarni, SK	1
Goldberg, JF; Thase, ME	1
Emory, H; Mizrahi, N	1
Estévez, RF; Gillman, PK; Hoffman, GR; Olson, MG; Schoffstall, AM; Stabio, ME; Van den Eynde, V	1

Reviews

4 review(s) available for tranylcypromine and selegiline

Article	Year
New drug trials in attention deficit disorder. Psychopharmacology bulletin, 1985, Volume: 21, Issue:2 Topics: Attention Deficit Disorder with Hyperactivity; Child; Clinical Trials as Topic; Clorgyline; Desipramine; Dextroamphetamine; Double-Blind Method; Fenfluramine; Humans; Male; Selegiline; Tranylcypromine	1985
Kinetics of MAO inhibitors. Modern problems of pharmacopsychiatry, 1983, Volume: 19 Topics: Animals; Humans; Hydrogen-Ion Concentration; Kinetics; Monoamine Oxidase Inhibitors; Phenelzine; Selegiline; Tranylcypromine	1983
Transdermal selegiline: the new generation of monoamine oxidase inhibitors. CNS spectrums, 2006, Volume: 11, Issue:5 Topics: Administration, Cutaneous; Depressive Disorder, Major; Drug Interactions; Humans; Monoamine Oxidase Inhibitors; Phenelzine; Selegiline; Tranylcypromine	2006
Classics in Chemical Neuroscience: Selegiline, Isocarboxazid, Phenelzine, and Tranylcypromine. ACS chemical neuroscience, 2023, 12-06, Volume: 14, Issue:23 Topics: Antidepressive Agents; Isocarboxazid; Monoamine Oxidase Inhibitors; Phenelzine; Selegiline; Tranylcypromine	2023

Trials

4 trial(s) available for tranylcypromine and selegiline

Article	Year
Tranylcypromine compared with L-deprenyl in Alzheimer's disease. Journal of clinical psychopharmacology, 1988, Volume: 8, Issue:1 Topics: Aged; Alzheimer Disease; Female; Humans; Male; Middle Aged; Phenethylamines; Psychiatric Status Rating Scales; Selegiline; Tranylcypromine	1988
New drug trials in attention deficit disorder. Psychopharmacology bulletin, 1985, Volume: 21, Issue:2 Topics: Attention Deficit Disorder with Hyperactivity; Child; Clinical Trials as Topic; Clorgyline; Desipramine; Dextroamphetamine; Double-Blind Method; Fenfluramine; Humans; Male; Selegiline; Tranylcypromine	1985
Experience with tranylcypromine in early Parkinson's disease. Journal of neural transmission. Supplementum, 1998, Volume: 52 Topics: Adult; Aged; Aged, 80 and over; Antiparkinson Agents; Depression; Erectile Dysfunction; Female; Follow-Up Studies; Humans; Levodopa; Male; Middle Aged; Monoamine Oxidase Inhibitors; Parkinson Disease; Selegiline; Sleep Initiation and Maintenance Disorders; Time Factors; Tranylcypromine; Tyramine	1998
Tyramine pressor sensitivity during treatment with the selegiline transdermal system 6 mg/24 h in healthy subjects. Journal of clinical pharmacology, 2006, Volume: 46, Issue:8 Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Blood Pressure; Cross-Over Studies; Dose-Response Relationship, Drug; Food-Drug Interactions; Heart Rate; Humans; Hypertension; Male; Middle Aged; Monoamine Oxidase Inhibitors; Reference Values; Selegiline; Time Factors; Tranylcypromine; Tyramine	2006

Other Studies

36 other study(ies) available for tranylcypromine and selegiline

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Studies of monoamine oxidases. Inhibition of bovine brain MAO in intact mitochondria by tricyclic antidepressant drugs. Biochemical pharmacology, 1979, Apr-01, Volume: 28, Issue:7 Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Cattle; Clorgyline; Drug Interactions; In Vitro Techniques; Kinetics; Mitochondria; Monoamine Oxidase Inhibitors; Phenethylamines; Selegiline; Serotonin; Substrate Specificity; Tranylcypromine	1979
Cumulative effects of irreversible MAO inhibitors in vivo. Biochemical pharmacology, 1979, Apr-01, Volume: 28, Issue:7 Topics: Animals; Brain; Clorgyline; Female; Liver; Monoamine Oxidase Inhibitors; Pargyline; Phenethylamines; Rats; Selegiline; Serotonin; Time Factors; Tranylcypromine	1979
The effect of monoamine oxidase inhibitors on some arylalkylamines in rate striatum. Journal of neurochemistry, 1979, Volume: 33, Issue:1 Topics: Amines; Animals; Clorgyline; Corpus Striatum; Iproniazid; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Phenethylamines; Rats; Selegiline; Tranylcypromine; Tryptamines; Tyramine	1979
Is tranylcypromine really metabolized to amphetamine? The Journal of clinical psychiatry, 1992, Volume: 53, Issue:12 Topics: Amphetamines; Animals; Humans; Rats; Selegiline; Tranylcypromine	1992
Antidepressants and brain respiration. Bioscience reports, 1991, Volume: 11, Issue:1 Topics: Amphetamine; Animals; Antidepressive Agents; Brain; Chlorides; Chlorpromazine; Clorgyline; Glucose; Imipramine; Lithium; Lithium Chloride; Male; Oxygen Consumption; Rats; Selegiline; Tranylcypromine	1991
Monoamine oxidase activity and monoamine metabolism in brains of parkinsonian patients treated with l-deprenyl. Journal of neurochemistry, 1986, Volume: 46, Issue:5 Topics: Aged; Amines; Brain; Dopamine; Female; Humans; Hydroxyindoleacetic Acid; Indans; Kynuramine; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Parkinson Disease; Phenethylamines; Selegiline; Serotonin; Tissue Distribution; Tranylcypromine	1986
Relationship between extracellular 5-hydroxytryptamine and behaviour following monoamine oxidase inhibition and L-tryptophan. British journal of pharmacology, 1988, Volume: 93, Issue:2 Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Clorgyline; Hydroxyindoleacetic Acid; Indoles; Male; Monoamine Oxidase Inhibitors; Rats; Rats, Inbred Strains; Selegiline; Serotonin; Time Factors; Tranylcypromine; Tryptophan; Tyrosine	1988
Inhibition of monoamine oxidase in monoaminergic neurones in the rat brain by irreversible inhibitors. Biochemical pharmacology, 1986, Apr-15, Volume: 35, Issue:8 Topics: Animals; Brain; Clorgyline; Dose-Response Relationship, Drug; Hydrazines; Hypothalamus; Iproniazid; Male; Monoamine Oxidase Inhibitors; Phenelzine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Serotonin; Reserpine; Selegiline; Tranylcypromine	1986
Reduced peripheral presynaptic adrenoceptor sensitivity following chronic antidepressant treatment in rats. British journal of pharmacology, 1985, Volume: 84, Issue:3 Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Clorgyline; Cocaine; Desipramine; Electric Stimulation; In Vitro Techniques; Liver; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Muscle Contraction; Muscle, Smooth; Norepinephrine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Neurotransmitter; Selegiline; Tranylcypromine; Vas Deferens	1985
Human plasma melatonin is elevated during treatment with the monoamine oxidase inhibitors clorgyline and tranylcypromine but not deprenyl. Psychiatry research, 1986, Volume: 17, Issue:2 Topics: Blood Platelets; Clorgyline; Depressive Disorder; Female; Humans; Male; Melatonin; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Receptors, Adrenergic, beta; Selegiline; Tranylcypromine	1986
Mysterious MAOI hypertensive episodes. The Journal of clinical psychiatry, 1986, Volume: 47, Issue:11 Topics: Adult; Anxiety Disorders; Humans; Hypertension; Male; Monoamine Oxidase Inhibitors; Panic; Phenelzine; Phenethylamines; Selegiline; Tranylcypromine	1986
Simultaneous liquid-chromatographic determination of 3,4-dihydroxyphenylglycol, catecholamines, and 3,4-dihydroxyphenylalanine in plasma, and their responses to inhibition of monoamine oxidase. Clinical chemistry, 1986, Volume: 32, Issue:11 Topics: Alzheimer Disease; Animals; Catecholamines; Chromatography, Liquid; Depression; Dihydroxyphenylalanine; Dogs; Glycols; Humans; Methoxyhydroxyphenylglycol; Monoamine Oxidase Inhibitors; Posture; Quality Control; Selegiline; Tranylcypromine	1986
Platelet monoamine oxidase inhibition by deprenyl and tranylcypromine: implications for clinical use. Biological psychiatry, 1985, Volume: 20, Issue:6 Topics: Blood Platelets; Depressive Disorder; Dose-Response Relationship, Drug; Humans; Monoamine Oxidase; Phenethylamines; Selegiline; Tranylcypromine	1985
Evidence that a preferred substrate for type B monoamine oxidase mediates stimulus properties of MAO inhibitors: a possible role for beta-phenylethylamine in the cocaine cue. Pharmacology, biochemistry, and behavior, 1980, Volume: 13, Issue:4 Topics: Animals; Cocaine; Cues; Discrimination Learning; Dose-Response Relationship, Drug; Generalization, Stimulus; Hydrazines; Male; Monoamine Oxidase Inhibitors; Nialamide; Pargyline; Rats; Selegiline; Tranylcypromine; Tryptamines	1980
Combination treatment with selective monoamine oxidase inhibitors and dopaminergic agonists in Parkinson's disease: biochemical and clinical observations. Advances in neurology, 1983, Volume: 37 Topics: Bromocriptine; Dopamine; Drug Therapy, Combination; Humans; Lisuride; Monoamine Oxidase Inhibitors; Parkinson Disease; Selegiline; Tranylcypromine	1983
Cardiovascular effects of (+)- and (-)-tranylcypromine compared to other monoamine oxidase inhibitors. Modern problems of pharmacopsychiatry, 1983, Volume: 19 Topics: Anesthesia; Animals; Blood Pressure; Cats; Dose-Response Relationship, Drug; Hemodynamics; Humans; Monoamine Oxidase Inhibitors; Myocardial Contraction; Pargyline; Reserpine; Selegiline; Stereoisomerism; Tranylcypromine	1983
Assessment of MAO inhibitors using postmortem human brain tissue: biochemical and therapeutic implications. Modern problems of pharmacopsychiatry, 1983, Volume: 19 Topics: Brain; Dopamine; Drug Evaluation, Preclinical; Humans; Monoamine Oxidase Inhibitors; Phenethylamines; Selegiline; Serotonin; Stereoisomerism; Tranylcypromine	1983
Partial or total protection from long-acting monoamine oxidase inhibitors (MAOIs) by new short-acting MAOIs of type A MD780515 and type B MD780236. Modern problems of pharmacopsychiatry, 1983, Volume: 19 Topics: Animals; Brain; Clorgyline; Dose-Response Relationship, Drug; Female; Liver; Male; Monoamine Oxidase Inhibitors; Myocardium; Oxazoles; Oxazolidinones; Rats; Rats, Inbred Strains; Selegiline; Tranylcypromine	1983
Behavioural hyperactivity in rats treated with selective monoamine oxidase inhibitors and LM 5008, a selective 5-hydroxytryptamine uptake blocker. British journal of pharmacology, 1983, Volume: 79, Issue:3 Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Clorgyline; Drug Combinations; Male; Monoamine Oxidase Inhibitors; Motor Activity; Piperidines; Rats; Rats, Inbred Strains; Selegiline; Tranylcypromine	1983
Monoamine oxidase in pancreatic islets, exocrine pancreas, and liver from rats. Characterization with clorgyline, deprenyl, pargyline, tranylcypromine, and amezinium. Naunyn-Schmiedeberg's archives of pharmacology, 1983, Volume: 324, Issue:3 Topics: Animals; Clorgyline; Female; Insulin; Insulin Secretion; Islets of Langerhans; Liver; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pancreas; Pargyline; Pyridazines; Rats; Rats, Inbred Strains; Selegiline; Tranylcypromine	1983
Monoamine oxidase inhibitors and histamine metabolism. Experientia, 1980, Jul-15, Volume: 36, Issue:7 Topics: Animals; Clorgyline; Histamine; Iproniazid; Male; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Rats; Selegiline; Tranylcypromine	1980
Dopamine metabolism in human brain: effect of monoamine oxidase inhibition in vitro by (-)deprenyl and (+) and (-) tranylcypromine. Journal of neural transmission. Supplementum, 1980, Issue:16 Topics: Aged; Brain; Caudate Nucleus; Dopamine; Humans; Oxidation-Reduction; Phenethylamines; Selegiline; Stereoisomerism; Tranylcypromine	1980
[Cardiovascular effects of (+)- and (-)-tranylcypromine compared to other monoamine oxidase inhibitors in animal studies (author's transl)]. Arzneimittel-Forschung, 1982, Volume: 32, Issue:3 Topics: Animals; Blood Pressure; Cats; Coronary Circulation; Drug Interactions; Female; Guinea Pigs; Male; Monoamine Oxidase Inhibitors; Myocardial Contraction; Norepinephrine; Pargyline; Selegiline; Stereoisomerism; Tranylcypromine; Tyramine	1982
Plasma 5-hydroxyindoleacetic acid as an indicator of monoamine oxidase-A inhibition in rat brain and peripheral tissues. Journal of neurochemistry, 1993, Volume: 61, Issue:6 Topics: Animals; Biomarkers; Brain; Chromatography, High Pressure Liquid; Clorgyline; Hydroxyindoleacetic Acid; Isoenzymes; Kinetics; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Rats; Rats, Wistar; Selegiline; Serotonin; Tranylcypromine	1993
Monoamine oxidase inhibitors increase preferentially extracellular 5-hydroxytryptamine in the midbrain raphe nuclei. A brain microdialysis study in the awake rat. Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 347, Issue:6 Topics: Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Clorgyline; Dialysis; Extracellular Space; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase Inhibitors; Raphe Nuclei; Rats; Rats, Wistar; Selegiline; Serotonin; Tranylcypromine	1993
Thyroid iodide transport is reduced by administration of monoamine oxidase A inhibitors to rats. The Journal of endocrinology, 1994, Volume: 143, Issue:2 Topics: Animals; Biological Transport; Clorgyline; Iodides; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Organ Culture Techniques; Pargyline; Rats; Rats, Wistar; Selegiline; Thyroid Gland; Tranylcypromine	1994
GABA-elevating effects of the antidepressant/antipanic drug phenelzine in brain: effects of pretreatment with tranylcypromine, (-)-deprenyl and clorgyline. Journal of affective disorders, 1995, Dec-13, Volume: 35, Issue:3 Topics: 4-Aminobutyrate Transaminase; Animals; Antidepressive Agents; Brain; Clorgyline; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Isoenzymes; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Phenelzine; Premedication; Rats; Rats, Sprague-Dawley; Selegiline; Tranylcypromine	1995
Inhibition of monoamine oxidase type A, but not type B, is an effective means of inducing anticonvulsant activity in the kindling model of epilepsy. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:3 Topics: Animals; Anticonvulsants; Brain; Coumarins; Electric Stimulation; Epilepsy, Temporal Lobe; Female; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Rats; Rats, Wistar; Selegiline; Tranylcypromine	1999
Limited potentiation of blood pressure response to oral tyramine by brain-selective monoamine oxidase A-B inhibitor, TV-3326 in conscious rabbits. Neuropharmacology, 2002, Volume: 43, Issue:6 Topics: 2-Hydroxyphenethylamine; Administration, Oral; Adrenergic Uptake Inhibitors; Animals; Blood Pressure; Brain; Clorgyline; Dose-Response Relationship, Drug; Drug Synergism; In Vitro Techniques; Indans; Intestines; Liver; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Rabbits; Selegiline; Serotonin; Tranylcypromine; Tyramine	2002
Antidepressant-like activity of corticotropin-releasing factor type-1 receptor antagonists in mice. European journal of pharmacology, 2004, Sep-19, Volume: 499, Issue:1-2 Topics: Animals; Antidepressive Agents; Clorgyline; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; Hindlimb Suspension; Male; Mice; Morpholines; Motor Activity; Paroxetine; Pyrazoles; Pyrimidines; Pyrroles; Reboxetine; Receptors, Corticotropin-Releasing Hormone; Selegiline; Swimming; Tranylcypromine; Triazines	2004
Leading the way: advances in the diagnosis, treatment, and management of neuropsychiatric illnesses. CNS spectrums, 2006, Volume: 11, Issue:5 Topics: Administration, Cutaneous; Administration, Topical; Brain; Depressive Disorder, Major; Humans; Mental Disorders; Monoamine Oxidase Inhibitors; Phenelzine; Psychiatry; Selegiline; Somatoform Disorders; Tranylcypromine	2006
Amine oxidases and their inhibitors: what can they tell us about neuroprotection and the development of drugs for neuropsychiatric disorders? Journal of psychiatry & neuroscience : JPN, 2007, Volume: 32, Issue:5 Topics: Amine Oxidase (Copper-Containing); Antidepressive Agents; Humans; Mental Disorders; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Phenelzine; RNA, Messenger; Selegiline; Tranylcypromine	2007
Antidepressant activity of curcumin: involvement of serotonin and dopamine system. Psychopharmacology, 2008, Volume: 201, Issue:3 Topics: Alkaloids; Animals; Antidepressive Agents; Behavior, Animal; Benzodioxoles; Biogenic Monoamines; Biological Availability; Curcumin; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Immobility Response, Tonic; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Piperidines; Polyunsaturated Alkamides; Reserpine; Selegiline; Serotonin; Swimming; Time Factors; Tranylcypromine	2008
Monoamine oxidase inhibitors revisited: what you should know. The Journal of clinical psychiatry, 2013, Volume: 74, Issue:2 Topics: Antidepressive Agents; Depressive Disorder; Drug Therapy, Combination; Humans; Isocarboxazid; Monoamine Oxidase Inhibitors; Phenelzine; Selegiline; Tranylcypromine; Tyramine	2013
Monoamine Oxidase Inhibition in a Patient With Type 1 Diabetes and Depression. Journal of diabetes science and technology, 2016, Volume: 10, Issue:5 Topics: Adult; Depressive Disorder; Diabetes Mellitus, Type 1; Female; Humans; Magnetic Resonance Imaging; Monoamine Oxidase Inhibitors; Selective Serotonin Reuptake Inhibitors; Selegiline; Tranylcypromine	2016