Page last updated: 2024-08-22

tranylcypromine and piperidines

tranylcypromine has been researched along with piperidines in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199020 (60.61)18.7374
1990's7 (21.21)18.2507
2000's4 (12.12)29.6817
2010's2 (6.06)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boulton, AA; Dyck, LE1
Da Prada, M; Keller, HH; Kettler, R1
Delini-Stula, A; Heath, WR; Schiwy, W1
Ashkenazi, R; Youdim, MB1
Dubicki, W; Goudie, AJ; Leathley, M1
Smith, DF1
Antonin, KH; Bieck, PR1
Bowman, Z; Cooper, CM; Stanton, HC1
Caló, A; Cardini, C; Quercia, V1
Kaverina, NV; Mirzoian, RS; Rozonov, IuB1
Chen, SC; Kasuya, Y; Munakata, H; Watanabe, H1
Baumann, PA; Bernasconi, R; Buech, O; Delini-Stula, A; Felner, AE; Sigg, K; Waldmeier, PC1
Ashkenazi, R; Finberg, JP; Youdim, MB1
Grahame-Smith, DG; Green, AR; Hammond, M; O'Shaughnessy, K; Schächter, M1
Antonin, KH; Bieck, P; Feldtrauer, JJ; Grunenwald, C; Lauber, J; Paul, E; Waldmeier, PC1
Antonin, KH; Bieck, P; Jedrychowski, M1
Bellaire, J; Heimann, H; Laux, G; Möller, HJ; Volz, HP1
Faltus, F; Magyar, I; Möller, HJ; Volz, HP1
Bakish, D; Bradwejn, J; Chouinard, G; Kennedy, SH; Kukha-Mohamad, SA; Kutcher, SP; Nair, NP; Remick, RA; Saxena, BM; Sharma, V1
Burgaud, JL; Oudart, N1
Bouvy, PF; Duivenvoorden, HJ; Haffmans, PM; Nolen, WA1
Artigas, F; Bel, N; Casanovas, JM; Romero, L1
ARIENS, EJ; HURKMANS, JA; van der SCHOOT, J; van ROSSUM, J1
FITZLOFF, J; PLOTNIKOFF, NP1
FUKUCHI, G1
SIEGLER, PE1
CROMLEY, WH; EBY, RZ; FELLOWS, EJ; FOWLER, PJ; PAULS, JF; TEDESCHI, DH1
Beanlands, RS; DaSilva, JN; Kenk, M; Lourenco, CM1
Gross, G; Groth, I; Jongen-Relo, A; Rex, A; Wicke, KM1
Fox, MA; Gallagher, PS; Jensen, CL; Murphy, DL1
Bhutani, MK; Bishnoi, M; Kulkarni, SK1
Charvet, C; Mast, N; Pikuleva, IA; Stout, CD1
Assareh, N; ElBatsh, MM; Kendall, DA; Marsden, CA1

Reviews

1 review(s) available for tranylcypromine and piperidines

ArticleYear
CURRENT STATUS OF DRUG TREATMENT IN THE DEPRESSIVE STATE.
    The Medical clinics of North America, 1964, Volume: 48

    Topics: Amitriptyline; Amphetamine; Amphetamines; Antidepressive Agents; Aspartic Acid; Benactyzine; Classification; Deanol; Depression; Desipramine; Humans; Imipramine; Isocarboxazid; Methylphenidate; Monoamine Oxidase Inhibitors; Nialamide; Pargyline; Pharmacology; Phenelzine; Phenmetrazine; Piperidines; Sympathomimetics; Toxicology; Tranylcypromine

1964

Trials

6 trial(s) available for tranylcypromine and piperidines

ArticleYear
Therapeutic and side-effect profile of a selective and reversible MAO-A inhibitor, brofaromine. Results of dose-finding trials in depressed patients.
    Journal of neural transmission. Supplementum, 1989, Volume: 28

    Topics: Adult; Aged; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Nomifensine; Piperidines; Psychiatric Status Rating Scales; Random Allocation; Tranylcypromine

1989
Oral tyramine pressor test and the safety of monoamine oxidase inhibitor drugs: comparison of brofaromine and tranylcypromine in healthy subjects.
    Journal of clinical psychopharmacology, 1988, Volume: 8, Issue:4

    Topics: Adolescent; Adult; Antidotes; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Male; Monoamine Oxidase Inhibitors; Phentolamine; Piperidines; Tranylcypromine; Tyramine

1988
Brofaromine in non-endogenous major depressed inpatients--results of a preliminary dose-finding trial versus tranylcypromine.
    Pharmacopsychiatry, 1994, Volume: 27, Issue:4

    Topics: Adolescent; Adult; Aged; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Piperidines; Psychiatric Status Rating Scales; Tranylcypromine

1994
Brofaromine in treatment-resistant depressed patients--a comparative trial versus tranylcypromine.
    Journal of affective disorders, 1994, Volume: 30, Issue:3

    Topics: Adult; Aged; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Personality Inventory; Piperidines; Tranylcypromine

1994
Brofaromine in depression: a Canadian multicenter placebo trial and a review of standard drug comparative studies.
    Clinical neuropharmacology, 1993, Volume: 16 Suppl 2

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Canada; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; Monoamine Oxidase Inhibitors; Phenelzine; Piperidines; Psychiatric Status Rating Scales; Tranylcypromine

1993
Monoamine oxidase inhibitors in resistant major depression. A double-blind comparison of brofaromine and tranylcypromine in patients resistant to tricyclic antidepressants.
    Journal of affective disorders, 1993, Volume: 28, Issue:3

    Topics: Adult; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypotension, Orthostatic; Male; Middle Aged; Monoamine Oxidase Inhibitors; Piperidines; Psychiatric Status Rating Scales; Sleep, REM; Tranylcypromine

1993

Other Studies

26 other study(ies) available for tranylcypromine and piperidines

ArticleYear
Reversible, amine--selective effects of acute and chronic brofaromine treatment in the rat.
    Life sciences, 1992, Volume: 51, Issue:1

    Topics: Animals; Biogenic Amines; Clorgyline; Corpus Striatum; Dose-Response Relationship, Drug; Drug Administration Schedule; Kinetics; Male; Monoamine Oxidase Inhibitors; Phenethylamines; Piperidines; Rats; Rats, Inbred Strains; Tranylcypromine; Tryptamines; Tyramine

1992
[Comparison of the new MAO-A inhibitors moclobemide, brofaromine and toloxatone with tranylcypromine in an animal experiment: significance for clinical practice].
    Psychiatrische Praxis, 1989, Volume: 16 Suppl 1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antidepressive Agents; Benzamides; Blood Pressure; Heart Rate; Moclobemide; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Piperidines; Rats; Serotonin; Structure-Activity Relationship; Tranylcypromine

1989
Serotonergic involvement in pharmacological action of the anxiolytic-sedatives thalidomide and supidimide.
    European journal of pharmacology, 1985, Dec-10, Volume: 119, Issue:1-2

    Topics: Animals; Anti-Anxiety Agents; Brain; Catecholamines; Clorgyline; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Male; Methoxydimethyltryptamines; Monoamine Oxidase; Motor Activity; p-Chloroamphetamine; Piperidines; Platelet Aggregation; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Thalidomide; Tranylcypromine; Tryptophan

1985
Paroxetine, a selective 5-hydroxytryptamine uptake inhibitor with antidepressant properties, lacks amphetamine-like stimulus properties in an operant drug discrimination bioassay in rodents.
    The Journal of pharmacy and pharmacology, 1988, Volume: 40, Issue:3

    Topics: Animals; Antidepressive Agents; Conditioning, Operant; Dextroamphetamine; Discrimination Learning; Discrimination, Psychological; Female; Flicker Fusion; Nomifensine; Paroxetine; Piperidines; Psychomotor Performance; Rats; Serotonin Antagonists; Tranylcypromine

1988
The stereoselectivity of serotonin uptake in brain tissue and blood platelets: the topography of the serotonin uptake area.
    Neuroscience and biobehavioral reviews, 1986,Spring, Volume: 10, Issue:1

    Topics: Alanine; Amphetamine; Aniline Compounds; Animals; Antidepressive Agents; Blood Platelets; Brain; Fluoxetine; Humans; Male; Methadone; Mianserin; Mirtazapine; Morpholines; Naphthalenes; Nefopam; Nomifensine; Paroxetine; Piperidines; Rabbits; Serotonin; Stereoisomerism; Tranylcypromine; Viloxazine; Zimeldine

1986
Effects of monoamine oxidase inhibitors on isoproterenol-induced cardiomegaly in rats.
    Toxicology and applied pharmacology, 1970, Volume: 16, Issue:1

    Topics: Animals; Carbon Isotopes; Cardiomegaly; DNA; Female; Glycine; Isocarboxazid; Isoniazid; Isoproterenol; Monoamine Oxidase Inhibitors; Myocardium; Nialamide; Nucleic Acids; Pargyline; Phenelzine; Piperidines; Pyrazines; Rats; RNA; Tranylcypromine

1970
Systematic application of gas chromatography to the analysis of pharmaceutical preparations.
    Journal of chromatography, 1968, Oct-08, Volume: 37, Issue:2

    Topics: Antidepressive Agents; Carisoprodol; Chromatography, Gas; Glutethimide; Humans; Hydroxyzine; Imipramine; Iproniazid; Isocarboxazid; Meprobamate; Methaqualone; Methods; Methylphenidate; Monoamine Oxidase Inhibitors; Nialamide; Phenelzine; Piperidines; Toxicology; Tranquilizing Agents; Tranylcypromine

1968
[The importance of central monoaminergic mechanisms in the effect of pharmacologic substances on the reflex reactions of the heart].
    Biulleten' eksperimental'noi biologii i meditsiny, 1967, Volume: 63, Issue:6

    Topics: Analgesics; Animals; Catecholamines; Cats; Coronary Vessels; Iproniazid; Isoproterenol; Monoamine Oxidase Inhibitors; Morphine; Piperidines; Reflex; Reserpine; Serotonin; Tranylcypromine; Vascular Resistance; Vasomotor System

1967
Effect of L-dopa, adrenergic -blockers and anticholinergic agents on the tremorine-tremor in mice.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 193, Issue:2

    Topics: Adrenergic beta-Antagonists; Amino Alcohols; Animals; Dihydroxyphenylalanine; Drug Combinations; Hydrazines; Isoproterenol; Male; Mice; Parasympatholytics; Phenethylamines; Piperidines; Propranolol; Stereoisomerism; Sympatholytics; Tranylcypromine; Tremor; Tremorine

1971
Characterization of a new, short-acting and specific inhibitor of type A monoamine oxidase.
    Modern problems of pharmacopsychiatry, 1983, Volume: 19

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain; Brain Chemistry; Female; Hemodynamics; Hydroxyindoleacetic Acid; Liver; Male; Methoxyhydroxyphenylglycol; Monoamine Oxidase Inhibitors; Piperidines; Rats; Rats, Inbred Strains; Serotonin Antagonists; Synaptosomes; Tranylcypromine

1983
Behavioural hyperactivity in rats treated with selective monoamine oxidase inhibitors and LM 5008, a selective 5-hydroxytryptamine uptake blocker.
    British journal of pharmacology, 1983, Volume: 79, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Clorgyline; Drug Combinations; Male; Monoamine Oxidase Inhibitors; Motor Activity; Piperidines; Rats; Rats, Inbred Strains; Selegiline; Tranylcypromine

1983
Inhibition of 5-hydroxytryptamine-mediated behaviour by the putative 5-HT2 antagonist pirenperone.
    Neuropharmacology, 1983, Volume: 22, Issue:5

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Haloperidol; Male; Methamphetamine; Motor Activity; Piperidines; Quipazine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tranylcypromine; Tryptophan

1983
Urinary excretion of O-methylated catecholamines, tyramine and phenyl-ethylamine by volunteers treated with tranylcypromine and CGP 11305 A.
    European journal of clinical pharmacology, 1983, Volume: 25, Issue:3

    Topics: Adult; Amphetamine; Epinephrine; Female; Humans; Male; Metanephrine; Monoamine Oxidase Inhibitors; Normetanephrine; Phenethylamines; Piperidines; Tranylcypromine; Tyramine

1983
Monoamine oxidase inhibition in healthy volunteers by CGP 11305 A, a new specific inhibitor of MAO-A.
    Modern problems of pharmacopsychiatry, 1983, Volume: 19

    Topics: Adult; Biogenic Amines; Blood Pressure; Female; Hemodynamics; Humans; Kinetics; Male; Monoamine Oxidase Inhibitors; Piperidines; Time Factors; Tranylcypromine

1983
Bronchodilatation of guinea-pig perfused bronchioles induced by the H3-receptor for histamine: role of epithelium.
    British journal of pharmacology, 1993, Volume: 109, Issue:4

    Topics: Acetylcholine; Animals; Anticonvulsants; Arginine; Bronchi; Bronchodilator Agents; Epithelium; Female; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; In Vitro Techniques; Indomethacin; Male; Methylhistamines; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Papaverine; Perfusion; Piperidines; Prostaglandins; Receptors, Histamine H3; Tranylcypromine

1993
Adaptative changes of the serotonergic system after antidepressant treatments.
    Advances in experimental medicine and biology, 1996, Volume: 398

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Clomipramine; Clorgyline; Fluvoxamine; Frontal Lobe; Hydroxyindoleacetic Acid; Imipramine; Microdialysis; Monoamine Oxidase Inhibitors; Piperidines; Pyrimidines; Raphe Nuclei; Rats; Serotonin; Stereotaxic Techniques; Tranylcypromine; Tryptophan

1996
Phenylisopropylamine derivatives, structure and action.
    Arzneimittel-Forschung, 1962, Volume: 12

    Topics: Amphetamine; Chlorpromazine; Dibucaine; Diethylpropion; Dihydroxyphenylalanine; Dopamine; Ephedrine; Epinephrine; Hydrazines; Imipramine; Iproniazid; Mephentermine; Methamphetamine; Methylphenidate; Movement; Nialamide; Phenelzine; Phenethylamines; Phenmetrazine; Phenylhydrazines; Piperidines; Reserpine; Tranylcypromine; Tryptophan; Tyramine

1962
EFFECT OF STIMULANTS ON ISOLATED RATS.
    Archives internationales de pharmacodynamie et de therapie, 1963, Oct-01, Volume: 145

    Topics: Amphetamine; Amphetamines; Animals; Avoidance Learning; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Hydrazines; Methylphenidate; Noise; Pharmacology; Piperidines; Rats; Research; Tranylcypromine

1963
[DRUGS ACTING ON THE NERVOUS SYSTEM. (2). WITH SPECIAL REFERENCE TO TRANQUILIZERS AND ANTIDEPRESSIVE AGENTS].
    [Chiryo] [Therapy], 1963, Volume: 45

    Topics: Amides; Amitriptyline; Antidepressive Agents; Benactyzine; Chemical Phenomena; Chemistry; Chlordiazepoxide; Desipramine; Diazepam; Haloperidol; Humans; Hydroxyzine; Hypnotics and Sedatives; Imipramine; Isocarboxazid; Meprobamate; Methylphenidate; Monoamine Oxidase Inhibitors; Nervous System; Nialamide; Pharmacology; Phenelzine; Piperidines; Tranquilizing Agents; Tranylcypromine; Tryptamines

1963
EFFECTS OF CENTRALLY ACTING DRUGS ON CONFINEMENT MOTOR ACTIVITY.
    Journal of pharmaceutical sciences, 1964, Volume: 53

    Topics: Behavior, Animal; Caffeine; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Methylphenidate; Motor Activity; Movement; Pharmacology; Phenmetrazine; Piperidines; Prochlorperazine; Rats; Research; Tranylcypromine; Trifluoperazine

1964
Increasing synaptic noradrenaline, serotonin and histamine enhances in vivo binding of phosphodiesterase-4 inhibitor (R)-[11C]rolipram in rat brain, lung and heart.
    Life sciences, 2006, Jun-20, Volume: 79, Issue:4

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Brain; Cyclic Nucleotide Phosphodiesterases, Type 4; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Heart; Histamine; Lung; Male; Myocardium; Neurotransmitter Agents; Norepinephrine; Phosphodiesterase Inhibitors; Piperidines; Positron-Emission Tomography; Rats; Rats, Sprague-Dawley; Rolipram; Selective Serotonin Reuptake Inhibitors; Serotonin; Synapses; Tranylcypromine

2006
The guinea pig forced swim test as a new behavioral despair model to characterize potential antidepressants.
    Psychopharmacology, 2007, Volume: 195, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Behavior, Animal; Central Nervous System Stimulants; Clozapine; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drugs, Investigational; Fluoxetine; Guinea Pigs; Injections, Intraperitoneal; Male; Methamphetamine; Monoamine Oxidase Inhibitors; Paroxetine; Piperidines; Selective Serotonin Reuptake Inhibitors; Swimming; Tranylcypromine

2007
Receptor mediation of exaggerated responses to serotonin-enhancing drugs in serotonin transporter (SERT)-deficient mice.
    Neuropharmacology, 2007, Volume: 53, Issue:5

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred C57BL; Mice, Knockout; Monoamine Oxidase Inhibitors; Piperazines; Piperidines; Polymorphism, Genetic; Pyridines; Receptors, Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Serotonin Syndrome; Tranylcypromine

2007
Antidepressant activity of curcumin: involvement of serotonin and dopamine system.
    Psychopharmacology, 2008, Volume: 201, Issue:3

    Topics: Alkaloids; Animals; Antidepressive Agents; Behavior, Animal; Benzodioxoles; Biogenic Monoamines; Biological Availability; Curcumin; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Immobility Response, Tonic; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Piperidines; Polyunsaturated Alkamides; Reserpine; Selegiline; Serotonin; Swimming; Time Factors; Tranylcypromine

2008
Structural basis of drug binding to CYP46A1, an enzyme that controls cholesterol turnover in the brain.
    The Journal of biological chemistry, 2010, Oct-08, Volume: 285, Issue:41

    Topics: Amino Acid Substitution; Anticonvulsants; Antidepressive Agents; Antifungal Agents; Brain; Catalytic Domain; Cholesterol; Cholesterol 24-Hydroxylase; Clotrimazole; Crystallography, X-Ray; Humans; Mutation, Missense; Piperidines; Protein Binding; Pyrimidines; Steroid Hydroxylases; Structure-Activity Relationship; Tranylcypromine; Triazoles; Voriconazole

2010
The effects of chronic administration of tranylcypromine and rimonabant on behaviour and protein expression in brain regions of the rat.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 100, Issue:3

    Topics: Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Element-Binding Protein; Depression; Drug Inverse Agonism; Frontal Lobe; Male; Monoamine Oxidase Inhibitors; Motor Activity; Nerve Tissue Proteins; Phosphorylation; Piperidines; Protein Processing, Post-Translational; Pyrazoles; Random Allocation; Rats; Rats, Inbred Strains; Receptor, Cannabinoid, CB1; Rimonabant; Signal Transduction; Tranylcypromine

2012