tranylcypromine has been researched along with lysine in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 5 (38.46) | 2.80 |
| Authors | Studies |
|---|---|
| Abdel Samed, MH; Akopyan, ZI; Gorkin, VZ; Kulygina, AA; Veryovkina, IV | 1 |
| Brooks, CL; Guvench, O; Price, DJ | 1 |
| Lee, MG; McCafferty, DG; Schmidt, DM; Shiekhattar, R; Wynder, C | 1 |
| McCafferty, DG; Schmidt, DM | 1 |
| Burnett, A; Casero, RA; Chen, WC; Dick, JE; Dugas, M; Göllner, S; Hebestreit, K; Howell, L; Jin, L; Klein, HU; Marton, L; Mills, K; Minden, MD; Müller-Tidow, C; Petrie, K; Popescu, AC; Schenk, T; Wang, JC; Woster, P; Zelent, A | 1 |
| Fukuhara, K; Hasegawa, M; Itoh, Y; Kakizawa, T; Mino, K; Miyata, N; Mizukami, T; Nakagawa, H; Ogasawara, D; Sasaki, R; Suzuki, T; Tsumoto, H | 1 |
| Afif, H; Benderdour, M; El Mansouri, FE; Fahmi, H; Kapoor, M; Martel-Pelletier, J; Nebbaki, SS; Pelletier, JP | 1 |
| Itoh, Y; Kakizawa, T; Ota, Y; Suzuki, T | 1 |
| Abdizadeh, R; Abdizadeh, T; Hadizadeh, F; Heidarian, E | 1 |
| Berthelet, J; Calegari-Silva, T; Cheeseman, K; Hamroune, J; Jannot, G; Letourneur, F; Lourenço, N; Rodrigues-Lima, F; Villares, M; Weitzman, JB | 1 |
| Gao, Y; Liu, HM; Liu, YJ; Wang, B; Zheng, YC | 1 |
| Li, L; Li, X; Li, Z; Ma, H; Ma, J; Ma, L; Qiao, Y; Song, J; Su, Y; Sun, Y; Wang, P; Xie, Z; Yuan, Y; Zhang, F; Zhang, X; Zhang, Z | 1 |
| Baby, S; Kulkarni, N; Sahu, B; Shinde, SD | 1 |
2 review(s) available for tranylcypromine and lysine
| Article | Year |
|---|---|
An Update of Lysine Specific Demethylase 1 Inhibitor: A Patent Review (2016-2020).
Topics: Antineoplastic Agents; Enzyme Inhibitors; Histone Demethylases; Humans; Lysine; Patents as Topic; Tranylcypromine | 2022 |
Lysine-Specific Demethylase 1 (LSD1) Inhibitors: Peptides as an Emerging Class of Therapeutics.
Topics: Enzyme Inhibitors; Histone Demethylases; Lysine; Peptides; Tranylcypromine | 2023 |
11 other study(ies) available for tranylcypromine and lysine
| Article | Year |
|---|---|
Effect of monoamine oxidase inhibitors on qualitative alterations in enzymatic properties of mitochondrial monoamine oxidases.
Topics: Animals; Copper; Deamination; Histamine; Iproniazid; Lysine; Male; Mitochondria, Liver; Monoamine Oxidase; Oleic Acids; Pargyline; Polyamines; Protein Denaturation; Rats; Tranylcypromine; Tyramine | 1971 |
Receptor rigidity and ligand mobility in trypsin-ligand complexes.
Topics: Animals; Arginine; Benzamidines; Cattle; Crystallography, X-Ray; Electrons; Hydrogen Bonding; Hydrolysis; Ligands; Lysine; Models, Chemical; Models, Molecular; Oxygen; Protein Binding; Proteins; Proteomics; Thermodynamics; Tranylcypromine; Trypsin | 2005 |
Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications.
Topics: Amidohydrolases; Antidepressive Agents; Cell Line; Enzyme Inhibitors; Histones; Humans; Lysine; Methylation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nucleosomes; Tranylcypromine | 2006 |
trans-2-Phenylcyclopropylamine is a mechanism-based inactivator of the histone demethylase LSD1.
Topics: Amino Acid Sequence; Catalytic Domain; Enzyme Inhibitors; Escherichia coli; Flavins; Histone Demethylases; Humans; Hydrogen-Ion Concentration; Kinetics; Lysine; Mass Spectrometry; Methylation; Models, Biological; Molecular Sequence Data; Molecular Structure; Monoamine Oxidase Inhibitors; Oxidoreductases, N-Demethylating; Protein Structure, Tertiary; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Temperature; Tranylcypromine | 2007 |
Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia.
Topics: Animals; Antigens, CD34; Apoptosis; CD11b Antigen; Cell Differentiation; Cells, Cultured; Cytokines; Disease Models, Animal; Drug Interactions; Enzyme Inhibitors; Female; Flow Cytometry; Gene Expression Regulation; Histone Demethylases; Humans; Leukemia, Myeloid, Acute; Lysine; Mice; Mice, Inbred NOD; Mice, SCID; RNA, Small Interfering; Stem Cell Factor; Time Factors; Transplants; Tranylcypromine; Tretinoin | 2012 |
Lysine-specific demethylase 1-selective inactivators: protein-targeted drug delivery mechanism.
Topics: Catalytic Domain; Crystallography, X-Ray; Drug Delivery Systems; Enzyme Inhibitors; Flavin-Adenine Dinucleotide; Histone Demethylases; Humans; Lysine; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Peptide Fragments; Small Molecule Libraries; Tranylcypromine | 2013 |
Lysine-specific demethylase 1-mediated demethylation of histone H3 lysine 9 contributes to interleukin 1β-induced microsomal prostaglandin E synthase 1 expression in human osteoarthritic chondrocytes.
Topics: Adult; Aged; Aged, 80 and over; Blotting, Western; Cells, Cultured; Chondrocytes; Gene Expression; Histone Demethylases; Histones; Humans; Interleukin-1beta; Intramolecular Oxidoreductases; Lysine; Methylation; Middle Aged; Monoamine Oxidase Inhibitors; Osteoarthritis; Pargyline; Promoter Regions, Genetic; Prostaglandin-E Synthases; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tranylcypromine | 2014 |
Design, Synthesis, and In Vitro Evaluation of Novel Histone H3 Peptide-Based LSD1 Inactivators Incorporating α,α-Disubstituted Amino Acids with γ-Turn-Inducing Structures.
Topics: Amino Acids; Amino Acids, Cyclic; Catalytic Domain; Cyclohexanecarboxylic Acids; Drug Design; Enzyme Assays; Enzyme Inhibitors; Histone Demethylases; Histones; Humans; Hydrolysis; Isoenzymes; Lysine; Methylation; Molecular Docking Simulation; Monoamine Oxidase; Peptides; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Structure-Activity Relationship; Tranylcypromine | 2018 |
QSAR Modeling, Molecular Docking and Molecular Dynamics Simulations Studies of Lysine-Specific Demethylase 1 (LSD1) Inhibitors as Anticancer Agents.
Topics: Antineoplastic Agents; Binding Sites; Drug Design; Enzyme Inhibitors; Histone Demethylases; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Lysine; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Quantitative Structure-Activity Relationship; Static Electricity; Tranylcypromine | 2021 |
Dynamic methylation of histone H3K18 in differentiating Theileria parasites.
Topics: Acetylation; Animals; Cattle; Cell Line; Chickens; Chromatin Immunoprecipitation Sequencing; Epigenetic Repression; Gene Expression Regulation, Developmental; HEK293 Cells; Histones; Humans; Insect Proteins; Life Cycle Stages; Lysine; Methylation; Methyltransferases; Mutagenesis, Site-Directed; Peptides, Cyclic; Recombinant Proteins; RNA-Seq; Theileria; Theileriasis; Tranylcypromine | 2021 |
Design, synthesis and in vitro/in vivo anticancer activity of tranylcypromine-based triazolopyrimidine analogs as novel LSD1 inhibitors.
Topics: Animals; Antineoplastic Agents; Enzyme Inhibitors; Histone Demethylases; Histones; Humans; Lysine; Mice; Structure-Activity Relationship; Tranylcypromine | 2023 |