Page last updated: 2024-08-22

tranylcypromine and levodopa

tranylcypromine has been researched along with levodopa in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199025 (83.33)18.7374
1990's3 (10.00)18.2507
2000's1 (3.33)29.6817
2010's1 (3.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Evans, JP; Grahame-Smith, DG; Green, AR; Tordoff, AF1
Boullin, DJ; Grahame-Smith, DG; Green, AR; Heal, DJ1
Murphy, DL1
Bloomfield, MR; Grahame-Smith, DG; Green, AR; Heal, DJ1
Barchas, JD; Watson, SJ1
Blalock, JA; Feldman, JM; Foster, LB; Zern, RT1
Corder, CN; Gray, JL; Kanefsky, TM; McDonald, RH; Redmond, DP1
Green, AR1
Connor, JD; Drust, EG; Sloviter, RS1
Deakin, JF; Green, AR1
Grahame-Smith, DG; Green, AR; Heal, DJ; Kelly, PH1
Green, AR; Mitchell, BD; Tordoff, AF; Youdim, MB1
Chapman, B; Feldman, JM2
Calne, DB; Findley, LJ; Lewis, PJ; Teychenne, PF1
Creese, I; Iversen, SD1
Green, AR; Kelly, PH1
Meltzer, HY; Parsa, MA; Ramirez, LF; Rohr, T1
Buckett, WR; Frankland, AT; Heal, DJ1
Davies, CL; Heal, DJ1
Buu, NT1
Cross, AJ; Dashwood, MJ; Deakin, JF; Owen, F1
Green, AR; Heal, DJ; Sabbagh, A; Youdim, MB1
Jones, RS1
Bird, JL; Feldman, JM; Zern, RT1
Grahame-Smith, DG; Green, AR; Nutt, DJ1
Chouinard, S; Fahn, S1
Driguès, N; Sagi, Y; Youdim, MB1
Gillman, PK1

Reviews

2 review(s) available for tranylcypromine and levodopa

ArticleYear
The behavioral toxicity of monoamine oxidase-inhibiting antidepressants.
    Advances in pharmacology and chemotherapy, 1977, Volume: 14

    Topics: Animals; Antidepressive Agents, Tricyclic; Behavior; Behavior, Animal; Dextroamphetamine; Humans; Hydrazines; Iproniazid; Isocarboxazid; Levodopa; Lithium; Monoamine Oxidase Inhibitors; Nialamide; Pargyline; Phenelzine; Procarbazine; Rats; Tranylcypromine; Tryptophan

1977
Advances pertaining to the pharmacology and interactions of irreversible nonselective monoamine oxidase inhibitors.
    Journal of clinical psychopharmacology, 2011, Volume: 31, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Drug Interactions; Humans; Levodopa; Monoamine Oxidase Inhibitors; Tranylcypromine

2011

Trials

1 trial(s) available for tranylcypromine and levodopa

ArticleYear
Experience with tranylcypromine in early Parkinson's disease.
    Journal of neural transmission. Supplementum, 1998, Volume: 52

    Topics: Adult; Aged; Aged, 80 and over; Antiparkinson Agents; Depression; Erectile Dysfunction; Female; Follow-Up Studies; Humans; Levodopa; Male; Middle Aged; Monoamine Oxidase Inhibitors; Parkinson Disease; Selegiline; Sleep Initiation and Maintenance Disorders; Time Factors; Tranylcypromine; Tyramine

1998

Other Studies

27 other study(ies) available for tranylcypromine and levodopa

ArticleYear
Electroconvulsive shock increases the behavioural responses of rats to brain 5-hydroxytryptamine accumulation and central nervous system stimulant drugs.
    British journal of pharmacology, 1976, Volume: 56, Issue:2

    Topics: Animals; Behavior, Animal; Brain; Central Nervous System Stimulants; Hydroxyindoleacetic Acid; Levodopa; Male; Motor Activity; Pentylenetetrazole; Rats; Serotonin; Stimulation, Chemical; Time Factors; Tranylcypromine; Tryptophan

1976
Single and repeated administration of neuroleptic drugs to rats: effects on striatal dopamine-sensitive adenylate cyclase and locomotor activity produced by tranylcypromine and L-tryptophan or L-Dopa.
    Psychopharmacology, 1976, Sep-29, Volume: 49, Issue:3

    Topics: Adenylyl Cyclase Inhibitors; Animals; Antipsychotic Agents; Corpus Striatum; Dopamine; Levodopa; Male; Motor Activity; Rats; Receptors, Dopamine; Serotonin; Tranylcypromine; Tryptophan

1976
Neuroleptic drugs block both the hyperactivity and the increase in caudate nucleus cyclic AMP concentration produced by the administration of tranylcypromine and L-dopa to rats.
    Psychopharmacology, 1978, Apr-28, Volume: 57, Issue:2

    Topics: Animals; Antipsychotic Agents; Brain Chemistry; Caudate Nucleus; Cyclic AMP; Dopamine; Levodopa; Male; Motor Activity; Norepinephrine; Rats; Tranylcypromine

1978
Histofluorescence in the unperfused CNS by cryostat and glyoxylic acid: a preliminary report.
    Psychopharmacology communications, 1975, Volume: 1, Issue:5

    Topics: Animals; Brain; Catecholamines; Glyoxylates; Levodopa; Male; Methods; Perfusion; Rats; Reserpine; Staining and Labeling; Tranylcypromine

1975
Characteristics of the dopaminergic and noradrenergic systems of the pancreatic islets.
    Diabetes, 1979, Volume: 28, Issue:3

    Topics: Animals; Cerebral Cortex; Cricetinae; Dopamine; Islets of Langerhans; Levodopa; Male; Median Eminence; Mesocricetus; Norepinephrine; Tranylcypromine

1979
Postural hypotension: adrenergic responsivity and levodopa therapy.
    Neurology, 1977, Volume: 27, Issue:10

    Topics: Adrenergic Fibers; Adult; Aged; Blood Pressure; Dopamine beta-Hydroxylase; Drug Evaluation; Drug Therapy, Combination; Ephedrine; Female; Fludrocortisone; Humans; Hypotension, Orthostatic; Isoproterenol; Levodopa; Male; Methoxamine; Middle Aged; Renin; Sympathomimetics; Tranylcypromine; Vanilmandelic Acid

1977
Repeated exposure of rats to the convulsant agent flurothyl enhances 5-hydroxytryptamine- and dopamine-mediated behavioural responses.
    British journal of pharmacology, 1978, Volume: 62, Issue:3

    Topics: Animals; Apomorphine; Dopamine; Electroshock; Flurothyl; Levodopa; Male; Methamphetamine; Motor Activity; Rats; Serotonin; Stimulation, Chemical; Time Factors; Tranylcypromine

1978
Specificity of a rat behavioral model for serotonin receptor activation.
    The Journal of pharmacology and experimental therapeutics, 1978, Volume: 206, Issue:2

    Topics: Aminooxyacetic Acid; Animals; Behavior, Animal; Brain Chemistry; Dopamine; Levodopa; Male; Methysergide; Models, Psychological; Monoamine Oxidase Inhibitors; Rats; Receptors, Serotonin; Serotonin; Tranylcypromine; Tryptamines

1978
The effects of putative 5-hydroxytryptamine antagonists on the behaviour produced by administration of tranylcypromine and L-tryptophan or tranylcypromine and L-DOPA to rats.
    British journal of pharmacology, 1978, Volume: 64, Issue:2

    Topics: Animals; Behavior, Animal; Brain; Drug Interactions; Levodopa; Male; Methyltyrosines; p-Chloroamphetamine; Propranolol; Rats; Serotonin; Serotonin Antagonists; Spinal Cord; Tranylcypromine; Tryptamines; Tryptophan

1978
The contrasting actions of TRH and cycloheximide in altering the effects of centrally acting drugs: evidence for the non-involvement of dopamine sensitive adenylate cyclase.
    Neuropharmacology, 1976, Volume: 15, Issue:10

    Topics: Adenylyl Cyclases; Amphetamines; Animals; Apomorphine; Caudate Nucleus; Cycloheximide; Dopamine; Drug Interactions; Hydroxydopamines; In Vitro Techniques; Levodopa; Male; Methamphetamine; Motor Activity; Norepinephrine; Pentylenetetrazole; Poly I-C; Rats; Receptors, Dopamine; Sleep; Thyrotropin-Releasing Hormone; Tranylcypromine; Tryptophan

1976
Orthostatic hypotension.
    The New England journal of medicine, 1977, 05-19, Volume: 296, Issue:20

    Topics: Drug Therapy, Combination; Humans; Hypotension, Orthostatic; Levodopa; Tranylcypromine

1977
Evidence for dopamine deamination by both type A and type B monoamine oxidase in rat brain in vivo and for the degree of inhibition of enzyme necessary for increased functional activity of dopamine and 5-hydroxytryptamine.
    British journal of pharmacology, 1977, Volume: 60, Issue:3

    Topics: Animals; Behavior, Animal; Brain; Brain Chemistry; Clorgyline; Deamination; Dopamine; Drug Interactions; Levodopa; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Motor Activity; Norepinephrine; Rats; Serotonin; Time Factors; Tranylcypromine; Tryptophan

1977
Monoamine oxidase inhibitors: nature of their interaction with rabbit pancreatic islets to alter insluin secretion.
    Diabetologia, 1975, Volume: 11, Issue:6

    Topics: 5-Hydroxytryptophan; Animals; Dopamine; Dose-Response Relationship, Drug; Harmine; Hydrazines; Insulin; Insulin Secretion; Iproniazid; Islets of Langerhans; Levodopa; Liver; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nialamide; Pargyline; Phenelzine; Rabbits; Serotonin; Time Factors; Tranylcypromine; Tryptamines

1975
Interactions of levodopa with inhibitors of monoamine oxidase and L-aromatic amino acid decarboxylase.
    Clinical pharmacology and therapeutics, 1975, Volume: 18, Issue:3

    Topics: Adult; Amino Acids; Blood Pressure; Carbidopa; Carboxy-Lyases; Drug Interactions; Humans; Levodopa; Male; Middle Aged; Monoamine Oxidase Inhibitors; Parkinson Disease; Stimulation, Chemical; Time Factors; Tranylcypromine

1975
Behavioral correlates of dopaminergic supersensitivity.
    Advances in neurology, 1975, Volume: 9

    Topics: Animals; Animals, Newborn; Apomorphine; Behavior; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Humans; Hydroxydopamines; Hypothalamus; Levodopa; Motor Activity; Nerve Degeneration; Rats; Receptors, Drug; Stereotyped Behavior; Substantia Nigra; Tranylcypromine; Tyrosine

1975
Evidence concerning the involvement of 5-hydroxytryptamine in the locomotor activity produced by amphetamine or tranylcypromine plus L-DOPA.
    British journal of pharmacology, 1976, Volume: 57, Issue:1

    Topics: Amphetamines; Animals; Disulfiram; Drug Interactions; Levodopa; Male; Methamphetamine; Motor Activity; p-Chloroamphetamine; Rats; Serotonin; Tranylcypromine

1976
Neuroleptic malignant syndrome without neuroleptics.
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:6

    Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Carbidopa; Depressive Disorder; Drug Combinations; Drug Therapy, Combination; Female; Humans; Levodopa; Neuroleptic Malignant Syndrome; Parkinson Disease; Substance Withdrawal Syndrome; Tranylcypromine; Tryptophan

1990
A new and highly sensitive method for measuring 3-methoxytyramine using HPLC with electrochemical detection. Studies with drugs which alter dopamine metabolism in the brain.
    Neuropharmacology, 1990, Volume: 29, Issue:12

    Topics: alpha-Methyltyrosine; Animals; Antidepressive Agents; Brain; Chromatography, High Pressure Liquid; Corpus Striatum; Dextroamphetamine; Dopamine; Dopamine Antagonists; Electrochemistry; Levodopa; Male; Methamphetamine; Methyltyrosines; Nucleus Accumbens; Pargyline; Rats; Rats, Inbred Strains; Tranylcypromine

1990
Determination of 3-methoxytyramine in rat brain by HPLC with electrochemical detection and its correlation with dopamine function after administration of a monoamine oxidase inhibitor and L-3,4-dihydroxyphenylalanine.
    Journal of neurochemistry, 1986, Volume: 47, Issue:6

    Topics: Animals; Brain Chemistry; Caudate Nucleus; Chromatography, High Pressure Liquid; Dopamine; Dose-Response Relationship, Drug; Levodopa; Male; Methamphetamine; Monoamine Oxidase Inhibitors; Motor Activity; Nucleus Accumbens; Rats; Rats, Inbred Strains; Tranylcypromine

1986
Relationship between catechol-O-methyltransferase and phenolsulfotransferase in the metabolism of dopamine in the rat brain.
    Journal of neurochemistry, 1985, Volume: 45, Issue:5

    Topics: Animals; Arylsulfotransferase; Brain; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Dopamine; Hydroxydopamines; Kinetics; Levodopa; Male; Oxidopamine; Pargyline; Pyrogallol; Rats; Rats, Inbred Strains; Sulfurtransferases; Tranylcypromine; Tropolone

1985
Mechanisms of catecholamine inactivation by the endocrine pancreas.
    Diabetes, 1974, Volume: 23, Issue:9

    Topics: Animals; Catechol O-Methyltransferase Inhibitors; Catecholamines; Cells, Cultured; Cocaine; Cricetinae; Culture Media; Dopamine; Drug Synergism; Imipramine; Insulin; Insulin Secretion; Islets of Langerhans; Levodopa; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nortriptyline; Pargyline; Rabbits; Rats; Species Specificity; Stimulation, Chemical; Tranylcypromine

1974
Studies on possible mechanisms of action of electroconvulsive therapy; effects of repeated electrically induced seizures on rat brain receptors for monoamines and other neurotransmitters.
    Psychopharmacology, 1981, Volume: 73, Issue:4

    Topics: Animals; Brain Chemistry; Dihydroalprenolol; Electroconvulsive Therapy; gamma-Aminobutyric Acid; Levodopa; Norepinephrine; Rats; Receptors, Dopamine; Receptors, Neurotransmitter; Serotonin; Tranylcypromine

1981
Behavioural effects of central and peripheral injection of various analogues and metabolites of thyrotropin releasing hormone (TRH).
    Neuropharmacology, 1981, Volume: 20, Issue:10

    Topics: Animals; Behavior, Animal; Injections; Levodopa; Male; Motor Activity; Nucleus Accumbens; Pentobarbital; Rats; Rats, Inbred Strains; Thyrotropin-Releasing Hormone; Tranylcypromine

1981
In vivo pharmacological studies on the interactions between tryptamine and 5-hydroxytryptamine.
    British journal of pharmacology, 1981, Volume: 73, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Chickens; Deglutition; Female; Fluoxetine; Levodopa; Male; Mice; p-Chloroamphetamine; Rats; Serotonin; Tranylcypromine; Tryptamines

1981
Effect of increased pancreatic islet norepinephrine, dopamine and serotonin concentration on insulin secretion in the golden hamster.
    Diabetologia, 1980, Volume: 18, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Blood Glucose; Cricetinae; Dopamine; Droxidopa; Insulin; Insulin Secretion; Islets of Langerhans; Levodopa; Mesocricetus; Norepinephrine; Serotonin; Tranylcypromine

1980
Enhanced 5-hydroxytryptamine and dopamine-mediated behavioural responses following convulsions--I. The effects of single and repeated bicuculline-induced seizures.
    Neuropharmacology, 1980, Volume: 19, Issue:9

    Topics: Animals; Behavior, Animal; Bicuculline; Dopamine; Levodopa; Male; Rats; Seizures; Serotonin; Time Factors; Tranylcypromine

1980
The neurochemical and behavioral effects of the novel cholinesterase-monoamine oxidase inhibitor, ladostigil, in response to L-dopa and L-tryptophan, in rats.
    British journal of pharmacology, 2005, Volume: 146, Issue:4

    Topics: Animals; Basal Ganglia; Behavior, Animal; Carbamates; Cholinesterase Inhibitors; Dopamine; Hippocampus; Hyperkinesis; Indans; Levodopa; Lewy Body Disease; Male; Monoamine Oxidase Inhibitors; Motor Activity; Muscarinic Antagonists; Norepinephrine; Phenylcarbamates; Rats; Rats, Sprague-Dawley; Rivastigmine; Scopolamine; Serotonin; Time Factors; Tranylcypromine; Tryptophan

2005