tranylcypromine has been researched along with isomethyleugenol in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (36.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 13 (52.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Frye, K; Schatz, RA; Sellinger, OZ | 1 |
| Fuentes, JA; Neff, NH; Oleshansky, MA | 1 |
| Leitz, FH; Stefano, FJ | 1 |
| Akin, FJ; Tobia, AJ | 1 |
| Ban, TA; Klingner, A; Lehmann, HE | 1 |
| Kalsner, S | 1 |
| Radouco-Thomas, S | 1 |
| Eade, NR; Renton, KW | 1 |
| Baker, GB; Baker, JM; Coutts, RT; LeGatt, DF | 1 |
| Lee, MG; McCafferty, DG; Schmidt, DM; Shiekhattar, R; Wynder, C | 1 |
| McCafferty, DG; Schmidt, DM | 1 |
| Belakavadi, M; Dell, J; Fondell, JD; Grover, GJ | 1 |
| Mao, C; Pan, D; Wang, YX | 1 |
| Chen, Z; He, Y; Li, H; Liu, I; Sun, S; Wang, Y; Yu, H | 1 |
| Chase, K; Sharma, RP | 1 |
| Afif, H; Benderdour, M; El Mansouri, FE; Fahmi, H; Kapoor, M; Martel-Pelletier, J; Nebbaki, SS; Pelletier, JP | 1 |
| Sun, Y; Xu, D; Xu, Z; Yuan, L; Zhang, F | 1 |
| DeSimone, J; Ibanez, V; Jagadeeswaran, R; Kouznetsova, T; Lavelle, D; Rivers, A; Ruiz, MA; Vaitkus, K | 1 |
| Deng, CY; Li, FR; Li, Y; Qi, H; Yan, HJ; Zhang, H; Zhou, SY | 1 |
| Ding, D; Guo, SW; Liu, X; Sun, Q | 1 |
| Chen, ZS; Liu, HM; Liu, Y; Yu, B; Zheng, YC | 1 |
| Ding, LN; Duan, YC; Guan, YY; Ma, CY; Ma, YC; Qin, WP; Yang, J; Zhai, XY; Zheng, YC; Zhu, YL | 1 |
| Chen, L; Deng, R; Jin, Y; Lavillette, D; Li, B; Li, D; Liang, R; Lui, K; Nie, J; Pan, W; Qian, Z; Shan, J; Shan, Z; Sun, B; Tsun, A; Xiong, R; Xu, K; Zhao, B; Zhao, H | 1 |
| Itoh, Y; Kakizawa, T; Ota, Y; Suzuki, T | 1 |
| Berthelet, J; Calegari-Silva, T; Cheeseman, K; Hamroune, J; Jannot, G; Letourneur, F; Lourenço, N; Rodrigues-Lima, F; Villares, M; Weitzman, JB | 1 |
2 review(s) available for tranylcypromine and isomethyleugenol
| Article | Year |
|---|---|
Epigenetic developmental programs and adipogenesis: implications for psychotropic induced obesity.
Topics: Adipogenesis; Animals; Antidepressive Agents; Cell Differentiation; Cell Proliferation; Energy Metabolism; Epigenesis, Genetic; Humans; Mental Disorders; Methylation; Obesity; Psychotropic Drugs; Tranylcypromine; Wnt Signaling Pathway | 2013 |
TCPs: privileged scaffolds for identifying potent LSD1 inhibitors for cancer therapy.
Topics: Animals; Antineoplastic Agents; Drug Design; Gene Expression Regulation, Neoplastic; Histone Demethylases; Humans; Methylation; Molecular Targeted Therapy; Neoplasms; Protein Processing, Post-Translational; Structure-Activity Relationship; Tranylcypromine | 2016 |
1 trial(s) available for tranylcypromine and isomethyleugenol
| Article | Year |
|---|---|
Nicotinic acid and catechol-O-methyl-transferase activity in schizophrenia.
Topics: Catechol O-Methyltransferase; Drug Interactions; Hallucinogens; Humans; Methionine; Methylation; Methyltransferases; Monoamine Oxidase Inhibitors; Nicotinic Acids; Placebos; Psychiatric Status Rating Scales; Schizophrenia; Tranylcypromine | 1973 |
22 other study(ies) available for tranylcypromine and isomethyleugenol
| Article | Year |
|---|---|
Increased in vivo methylation of [3H]histamine in the methionine sulfoximine epileptogenic mouse brain.
Topics: Animals; Brain; Deamination; Histamine; Histidine; Histidine Decarboxylase; Male; Methionine Sulfoximine; Methylation; Mice; Seizures; Tranylcypromine | 1978 |
A sensitive enzymatic assay for dextro- or levo-tranylcypromine in brain.
Topics: Amines; Animals; Brain Chemistry; In Vitro Techniques; Lung; Male; Methods; Methylation; Methyltransferases; Rabbits; Rats; S-Adenosylmethionine; Stereoisomerism; Tranylcypromine | 1975 |
The effect of tyramine, amphetamine and metaraminol on the metabolic disposition of 3 H-norepinephrine released from the adrenergic neuron.
Topics: Adrenergic Agents; Amphetamine; Animals; Benzene Derivatives; Guanethidine; Guanidines; Heart; In Vitro Techniques; Male; Metaraminol; Methylation; Monoamine Oxidase Inhibitors; Myocardium; Neurons; Norepinephrine; Normetanephrine; Perfusion; Quinolizines; Rats; Stimulation, Chemical; Sympathetic Nervous System; Tranylcypromine; Tritium; Tyramine | 1971 |
Drug-induced modification of ( 3 H)-histamine catabolism in the rat hypothalamus in vivo.
Topics: Acetates; Amines; Animals; Biodegradation, Environmental; Deamination; Guanidines; Histamine; Hypothalamus; Imidazoles; Iproniazid; Male; Methylation; Perfusion; Rats; Rats, Inbred Strains; Stereotaxic Techniques; Tranylcypromine; Tritium | 1972 |
Effects of tyramine on responses to and inactivation of histamine in aortic strips.
Topics: Amine Oxidase (Copper-Containing); Amodiaquine; Animals; Aorta; Catecholamines; Chlorpheniramine; Cocaine; Diffusion; Histamine; Imidazoles; In Vitro Techniques; Iproniazid; Methylation; Muscle Contraction; Muscles; Oils; Phentolamine; Quinidine; Rabbits; Reserpine; Semicarbazides; Tranylcypromine; Tyramine | 1970 |
[Extrapyramidal syndrome in animal experiments: rôle of calcium and o-methylated derivatives].
Topics: Animals; Calcium; Calcium Metabolism Disorders; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Extrapyramidal Tracts; Guinea Pigs; Hydrogen-Ion Concentration; Methylation; Movement Disorders; Norepinephrine; Parkinson Disease; Pyrogallol; Rats; Reserpine; Serotonin Antagonists; Stimulation, Chemical; Synapses; Tranylcypromine | 1970 |
Effect of monoamine oxidase inhibitors on the N-demethylation and hydrolysis of meperidine.
Topics: Amphetamine; Animals; Dealkylation; Dextroamphetamine; Ethanol; Hydrolysis; In Vitro Techniques; Iproniazid; Kinetics; Male; Meperidine; Methylation; Microsomes, Liver; Monoamine Oxidase Inhibitors; Pargyline; Phenelzine; Proadifen; Rats; Statistics as Topic; Stereoisomerism; Tranylcypromine | 1970 |
A comparison of the effects of chronic administration of tranylcypromine and phenelzine on rat brain levels of the catecholamines and their O-methylated metabolites.
Topics: Animals; Brain Chemistry; Catecholamines; Male; Methylation; Phenelzine; Rats; Rats, Inbred Strains; Tranylcypromine | 1983 |
Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications.
Topics: Amidohydrolases; Antidepressive Agents; Cell Line; Enzyme Inhibitors; Histones; Humans; Lysine; Methylation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nucleosomes; Tranylcypromine | 2006 |
trans-2-Phenylcyclopropylamine is a mechanism-based inactivator of the histone demethylase LSD1.
Topics: Amino Acid Sequence; Catalytic Domain; Enzyme Inhibitors; Escherichia coli; Flavins; Histone Demethylases; Humans; Hydrogen-Ion Concentration; Kinetics; Lysine; Mass Spectrometry; Methylation; Models, Biological; Molecular Sequence Data; Molecular Structure; Monoamine Oxidase Inhibitors; Oxidoreductases, N-Demethylating; Protein Structure, Tertiary; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Temperature; Tranylcypromine | 2007 |
Thyroid hormone suppression of β-amyloid precursor protein gene expression in the brain involves multiple epigenetic regulatory events.
Topics: Acetylation; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Cell Line, Tumor; Epigenesis, Genetic; Gene Expression Regulation; Histone Deacetylase Inhibitors; Histone Demethylases; Histones; Humans; Hydroxamic Acids; Male; Methylation; Promoter Regions, Genetic; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Receptors, Thyroid Hormone; Tranylcypromine; Triiodothyronine | 2011 |
Suppression of gluconeogenic gene expression by LSD1-mediated histone demethylation.
Topics: DNA Helicases; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression; Gene Knockdown Techniques; Gluconeogenesis; Glucose; Glucose-6-Phosphatase; Hep G2 Cells; Histone Demethylases; Histones; Humans; Methylation; Promoter Regions, Genetic; Protein Processing, Post-Translational; RNA-Binding Proteins; Transcriptional Activation; Tranylcypromine | 2013 |
Trans-2-phenylcyclopropylamine regulates zebrafish lateral line neuromast development mediated by depression of LSD1 activity.
Topics: Animals; Apoptosis; Blotting, Western; Cell Proliferation; Gene Expression Regulation, Developmental; Hair Cells, Auditory; Histone Demethylases; Histones; Larva; Lateral Line System; Mechanoreceptors; Methylation; Monoamine Oxidase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Tranylcypromine; Zebrafish; Zebrafish Proteins | 2013 |
Lysine-specific demethylase 1-mediated demethylation of histone H3 lysine 9 contributes to interleukin 1β-induced microsomal prostaglandin E synthase 1 expression in human osteoarthritic chondrocytes.
Topics: Adult; Aged; Aged, 80 and over; Blotting, Western; Cells, Cultured; Chondrocytes; Gene Expression; Histone Demethylases; Histones; Humans; Interleukin-1beta; Intramolecular Oxidoreductases; Lysine; Methylation; Middle Aged; Monoamine Oxidase Inhibitors; Osteoarthritis; Pargyline; Promoter Regions, Genetic; Prostaglandin-E Synthases; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tranylcypromine | 2014 |
Epigenetic regulation of Atrophin1 by lysine-specific demethylase 1 is required for cortical progenitor maintenance.
Topics: Animals; Binding Sites; Cell Differentiation; Cell Line; Cell Proliferation; Cerebral Cortex; Embryo, Mammalian; Epigenesis, Genetic; Gene Expression Regulation, Developmental; HEK293 Cells; Histone Demethylases; Histones; Humans; Methylation; Monoamine Oxidase Inhibitors; Nerve Tissue Proteins; Neural Stem Cells; Primary Cell Culture; Protein Binding; Rats; RNA, Small Interfering; Tranylcypromine | 2014 |
RN-1, a potent and selective lysine-specific demethylase 1 inhibitor, increases γ-globin expression, F reticulocytes, and F cells in a sickle cell disease mouse model.
Topics: Anemia, Sickle Cell; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Erythroid Precursor Cells; Erythropoiesis; Fetal Hemoglobin; gamma-Globins; Gene Expression Regulation; Hematopoietic Stem Cells; Histone Demethylases; Histones; Humans; Hydroxyurea; Methylation; Mice; Mice, Transgenic; Papio; Protein Processing, Post-Translational; Reticulocytes; Transgenes; Tranylcypromine; Tretinoin; U937 Cells | 2015 |
The effects of LSD1 inhibition on self-renewal and differentiation of human induced pluripotent stem cells.
Topics: Cell Differentiation; Cell Line; Cell Proliferation; Cell Self Renewal; Histone Demethylases; Histones; Humans; Induced Pluripotent Stem Cells; Methylation; Phenelzine; RNA Interference; Tranylcypromine | 2016 |
Tranylcypromine, a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis.
Topics: Animals; Biomarkers; Cell Proliferation; Endometriosis; Female; Histone Code; Histone Demethylases; Histones; Hyperalgesia; Immunohistochemistry; Methylation; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Neovascularization, Pathologic; Tranylcypromine | 2016 |
Design and synthesis of tranylcypromine derivatives as novel LSD1/HDACs dual inhibitors for cancer treatment.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histone Demethylases; Humans; Methylation; Molecular Docking Simulation; Neoplasms; Tranylcypromine | 2017 |
Histone demethylase LSD1 restricts influenza A virus infection by erasing IFITM3-K88 monomethylation.
Topics: Animals; Binding Sites; Disease Progression; Enzyme Inhibitors; Female; HEK293 Cells; Histone Demethylases; Host-Pathogen Interactions; Humans; Influenza A virus; Membrane Proteins; Methylation; Mice; Mice, Inbred BALB C; Mice, Knockout; Models, Biological; Orthomyxoviridae Infections; RNA-Binding Proteins; Tranylcypromine; Vesicular stomatitis Indiana virus; Virus Replication; Zika Virus | 2017 |
Design, Synthesis, and In Vitro Evaluation of Novel Histone H3 Peptide-Based LSD1 Inactivators Incorporating α,α-Disubstituted Amino Acids with γ-Turn-Inducing Structures.
Topics: Amino Acids; Amino Acids, Cyclic; Catalytic Domain; Cyclohexanecarboxylic Acids; Drug Design; Enzyme Assays; Enzyme Inhibitors; Histone Demethylases; Histones; Humans; Hydrolysis; Isoenzymes; Lysine; Methylation; Molecular Docking Simulation; Monoamine Oxidase; Peptides; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Structure-Activity Relationship; Tranylcypromine | 2018 |
Dynamic methylation of histone H3K18 in differentiating Theileria parasites.
Topics: Acetylation; Animals; Cattle; Cell Line; Chickens; Chromatin Immunoprecipitation Sequencing; Epigenetic Repression; Gene Expression Regulation, Developmental; HEK293 Cells; Histones; Humans; Insect Proteins; Life Cycle Stages; Lysine; Methylation; Methyltransferases; Mutagenesis, Site-Directed; Peptides, Cyclic; Recombinant Proteins; RNA-Seq; Theileria; Theileriasis; Tranylcypromine | 2021 |