Compounds > trans-1,4-bis(2-chlorobenzaminomethyl)cyclohexane dihydrochloride
Page last updated: 2024-08-21

trans-1,4-bis(2-chlorobenzaminomethyl)cyclohexane dihydrochloride and triparanol

trans-1,4-bis(2-chlorobenzaminomethyl)cyclohexane dihydrochloride has been researched along with triparanol in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19908 (61.54)18.7374
1990's2 (15.38)18.2507
2000's2 (15.38)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Balogh, I; Kim, HY; Koczok, K; Korade, Z; Liu, W; Mirnics, K; Porter, NA; Tallman, KA; Xu, L1
Andiman, RM; Bowman, RL; Campion, DS; Dromgoole, SH; Nagatomo, T; Peter, JB; Stempel, KE1
Fischer, VW; Ramsey, RB2
Ramsey, RB2
Dupuis, R; Giroud, A; Horvath, C; Roux, C1
Kacew, S; Reasor, MJ1
Glossmann, H; Hanner, M; Moebius, FF; Reiter, RJ1
Beachy, PA; Cooper, MK; Porter, JA; Young, KE1
Chevy, F; Citadelle, D; Cormier, V; Gaoua, W; Mulliez, N; Roux, C; Wolf, C1
DVORNIK, D; GIVNER, ML1
Busto, R; Cano, S; Dávalos, A; de la Peña, G; Giera, M; Herrera, E; Lasunción, MA; Sánchez-Wandelmer, J1

Reviews

1 review(s) available for trans-1,4-bis(2-chlorobenzaminomethyl)cyclohexane dihydrochloride and triparanol

ArticleYear
Role of cholesterol in embryonic development.
    The American journal of clinical nutrition, 2000, Volume: 71, Issue:5 Suppl

    Topics: Animals; Anticholesteremic Agents; Cholesterol; Dehydrocholesterols; Disease Models, Animal; Embryonic and Fetal Development; Fetus; Piperazines; Rats; Smith-Lemli-Opitz Syndrome; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride; Triparanol

2000

Other Studies

12 other study(ies) available for trans-1,4-bis(2-chlorobenzaminomethyl)cyclohexane dihydrochloride and triparanol

ArticleYear
The Effect of Small Molecules on Sterol Homeostasis: Measuring 7-Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts.
    Journal of medicinal chemistry, 2016, Feb-11, Volume: 59, Issue:3

    Topics: Animals; Cell Line; Dehydrocholesterols; Dose-Response Relationship, Drug; Fibroblasts; Homeostasis; Humans; Mice; Molecular Conformation; Neurons; Oxidoreductases Acting on CH-CH Group Donors; Small Molecule Libraries; Sterols; Structure-Activity Relationship

2016
Experimental myotonia and hypocholesterolemic agents.
    Experimental neurology, 1975, Volume: 49, Issue:1 Pt 1

    Topics: Adenosine Triphosphatases; Animals; Anticholesteremic Agents; Cell Membrane; Cholesterol; Electromyography; Erythrocytes; Male; Muscles; Myotonia; Rats; Sterols; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride; Triparanol

1975
Effects of zuclomiphene in combination with triparanol and ay-9944 on developing rat CNS morphology and biochemistry.
    Acta neuropathologica, 1977, Jul-15, Volume: 39, Issue:1

    Topics: Animals; Axons; Brain; Brain Chemistry; Cholesterol; Clomiphene; Cyclohexanes; Desmosterol; Enclomiphene; Female; Inclusion Bodies; Male; Microscopy, Electron; Rats; Spinal Cord; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride; Triparanol

1977
Effect of extended hypocholesterolemic drug treatment on peripheral and central nervous system sterol content of the rat.
    Lipids, 1977, Volume: 12, Issue:10

    Topics: Animals; Anticholesteremic Agents; Azacosterol; Central Nervous System; Clomiphene; Desmosterol; Female; Isomerism; Male; Peripheral Nerves; Rats; Sterols; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride; Triparanol

1977
Effect of hypocholesterolemic agents on central nervous system cholesterol biosynthesis III. Zuclomiphene in combination with AY9944 and triparanol.
    Biochemical pharmacology, 1978, Volume: 27, Issue:12

    Topics: Animals; Anticholesteremic Agents; Brain; Cholesterol; Clomiphene; Drug Interactions; Female; Male; Rats; Sterols; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride; Triparanol

1978
Interpretation of isolated agenesis of the pituitary.
    Teratology, 1979, Volume: 19, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Brain; Cyclohexanes; Female; Humans; Pituitary Gland; Pregnancy; Rats; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride; Triparanol

1979
Newborn response to cationic amphiphilic drugs.
    Federation proceedings, 1985, Volume: 44, Issue:7

    Topics: Animals; Animals, Newborn; Chlorphentermine; Dexamethasone; Drug Interactions; Female; Fetus; Gentamicins; Lipidoses; Lung; Phenobarbital; Phentermine; Phospholipids; Piperazines; Pregnancy; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride; Triparanol

1985
The biochemical and morphological response of hydrolytic enzymes in the developing brain to hypocholesterolemic agents.
    Acta neuropathologica, 1980, Volume: 49, Issue:2

    Topics: Acetylglucosaminidase; Acid Phosphatase; Alkaline Phosphatase; Animals; Anticholesteremic Agents; Brain; Brain Chemistry; Female; Glucuronidase; Hydrolases; Male; Proteins; Rats; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride; Triparanol

1980
High affinity of sigma 1-binding sites for sterol isomerization inhibitors: evidence for a pharmacological relationship with the yeast sterol C8-C7 isomerase.
    British journal of pharmacology, 1997, Volume: 121, Issue:1

    Topics: Animals; Binding Sites; Brain; Calcium Channel Blockers; Clomiphene; Estrogen Antagonists; Excitatory Amino Acid Antagonists; Fertility Agents, Female; Fungicides, Industrial; Guinea Pigs; Hypolipidemic Agents; Isoquinolines; Isotope Labeling; Microsomes; Microsomes, Liver; Morpholines; Pentazocine; Piperidines; Receptors, sigma; Saccharomyces cerevisiae; Stereoisomerism; Steroid Isomerases; Tamoxifen; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride; Triparanol; Verapamil

1997
Teratogen-mediated inhibition of target tissue response to Shh signaling.
    Science (New York, N.Y.), 1998, Jun-05, Volume: 280, Issue:5369

    Topics: Abnormalities, Drug-Induced; Animals; Cell Membrane; Central Nervous System; Chick Embryo; Cholesterol; Culture Techniques; DNA-Binding Proteins; Endoplasmic Reticulum; Hedgehog Proteins; Hepatocyte Nuclear Factor 3-beta; Holoprosencephaly; Homeodomain Proteins; LIM-Homeodomain Proteins; Membrane Proteins; Muscle Proteins; Nerve Tissue Proteins; Nuclear Proteins; Patched Receptors; PAX7 Transcription Factor; Proteins; Receptors, Cell Surface; Signal Transduction; Teratogens; Tomatine; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride; Trans-Activators; Transcription Factors; Triparanol; Veratrum Alkaloids

1998
INHIBITION OF ADRENAL CHOLESTEROGENESIS IN VITRO BY AY-9944, 22,25-DIAZACHOLESTANOL AND BY TRIPARANOL.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 117

    Topics: Acetates; Adrenal Glands; Animals; Anticholesteremic Agents; Cattle; Cholestanols; Cholesterol; Glucose; In Vitro Techniques; Lipid Metabolism; Oxidoreductases; Pharmacology; Research; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride; Triparanol

1964
Inhibition of cholesterol biosynthesis disrupts lipid raft/caveolae and affects insulin receptor activation in 3T3-L1 preadipocytes.
    Biochimica et biophysica acta, 2009, Volume: 1788, Issue:9

    Topics: 3T3-L1 Cells; Animals; Caveolae; Caveolin 1; Cell Membrane; Cholesterol; Dehydrocholesterols; Enzyme Inhibitors; G(M1) Ganglioside; Lanosterol; Membrane Microdomains; Mice; Receptor, Insulin; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride; Triparanol

2009