Compounds > trans-1,4-bis(2-chlorobenzaminomethyl)cyclohexane dihydrochloride
Page last updated: 2024-08-21

trans-1,4-bis(2-chlorobenzaminomethyl)cyclohexane dihydrochloride and lovastatin

trans-1,4-bis(2-chlorobenzaminomethyl)cyclohexane dihydrochloride has been researched along with lovastatin in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Balogh, I; Kim, HY; Koczok, K; Korade, Z; Liu, W; Mirnics, K; Porter, NA; Tallman, KA; Xu, L1
Gaylor, JL; Jeon, KI; Johng, TN; Kim, CK; Lim, DM; Paik, YK; Trzaskos, JM1
De Luca, F; Wu, S1
Cortez, MA; Cunnane, SC; Ryan, MA; Serbanescu, I; Shukla, R; Snead, OC1
Charish, J; Farhani, N; Feng, J; Koeberle, PD; Monnier, PP; Mothe, AJ; Qin, X; Shabanzadeh, AP; Sugita, S; Tassew, NG; Wälchli, T1

Other Studies

5 other study(ies) available for trans-1,4-bis(2-chlorobenzaminomethyl)cyclohexane dihydrochloride and lovastatin

ArticleYear
The Effect of Small Molecules on Sterol Homeostasis: Measuring 7-Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts.
    Journal of medicinal chemistry, 2016, Feb-11, Volume: 59, Issue:3

    Topics: Animals; Cell Line; Dehydrocholesterols; Dose-Response Relationship, Drug; Fibroblasts; Homeostasis; Humans; Mice; Molecular Conformation; Neurons; Oxidoreductases Acting on CH-CH Group Donors; Small Molecule Libraries; Sterols; Structure-Activity Relationship

2016
Cholesterol biosynthesis from lanosterol: regulation and purification of rat hepatic sterol 14-reductase.
    Biochimica et biophysica acta, 1995, Oct-26, Volume: 1259, Issue:1

    Topics: Animals; Anticholesteremic Agents; Cholesterol; Cholesterol, Dietary; Cholestyramine Resin; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Homeostasis; Kinetics; Lanosterol; Lovastatin; Male; Microsomes, Liver; Oxidoreductases; Rats; Rats, Sprague-Dawley; Time Factors; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride

1995
Role of cholesterol in the regulation of growth plate chondrogenesis and longitudinal bone growth.
    The Journal of biological chemistry, 2004, Feb-06, Volume: 279, Issue:6

    Topics: Animals; Anticholesteremic Agents; Bone Development; Cholesterol; Chondrogenesis; Growth Plate; Hedgehog Proteins; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Lovastatin; Rats; Rats, Sprague-Dawley; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride; Trans-Activators

2004
Lovastatin exacerbates atypical absence seizures with only minimal effects on brain sterols.
    Journal of lipid research, 2004, Volume: 45, Issue:11

    Topics: Animals; Body Weight; Brain; Cholesterol; Dehydrocholesterols; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Inhibitors; Epilepsy, Absence; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Models, Biological; Rats; Rats, Long-Evans; Sterols; Time Factors; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride

2004
Cholesterol synthesis inhibition promotes axonal regeneration in the injured central nervous system.
    Neurobiology of disease, 2021, Volume: 150

    Topics: Animals; Anticholesteremic Agents; Axons; Cell Survival; Chick Embryo; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Membrane Microdomains; Membrane Proteins; Myelin Sheath; Nerve Regeneration; Neurons; Optic Nerve; Optic Nerve Injuries; Photoreceptor Cells; Prenylation; Prodrugs; Rats; Retina; Retinitis Pigmentosa; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride

2021