Page last updated: 2024-09-02

trans-1,2-dihydro-1,2-naphthalenediol and benzo(a)pyrene

trans-1,2-dihydro-1,2-naphthalenediol has been researched along with benzo(a)pyrene in 4 studies

Compound Research Comparison

Studies
(trans-1,2-dihydro-1,2-naphthalenediol)
Trials
(trans-1,2-dihydro-1,2-naphthalenediol)
Recent Studies (post-2010)
(trans-1,2-dihydro-1,2-naphthalenediol)
Studies
(benzo(a)pyrene)
Trials
(benzo(a)pyrene)
Recent Studies (post-2010) (benzo(a)pyrene)
290157,311172,154

Protein Interaction Comparison

ProteinTaxonomytrans-1,2-dihydro-1,2-naphthalenediol (IC50)benzo(a)pyrene (IC50)
Cytochrome P450 1A2Homo sapiens (human)0.04
Amine oxidase [flavin-containing] AHomo sapiens (human)5.972

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Doehmer, J; Jacob, J; Kabler, SL; Morrow, CS; Seidel, A; Townsend, AJ1
García de Llasera, MP; Hernández Blanco, FJ1
Mor, G; Wang, R; Wang, W; Zhang, H; Zhang, Q1
Guo, CC; Li, ZF; Lyu, Y; Ren, XK; Zheng, JP1

Other Studies

4 other study(ies) available for trans-1,2-dihydro-1,2-naphthalenediol and benzo(a)pyrene

ArticleYear
Differential protection by human glutathione S-transferase P1 against cytotoxicity of benzo[a]pyrene, dibenzo[a,l]pyrene, or their dihydrodiol metabolites, in bi-transgenic cell lines that co-express rat versus human cytochrome P4501A1.
    Chemico-biological interactions, 2009, May-15, Volume: 179, Issue:2-3

    Topics: Animals; Benzo(a)pyrene; Cell Proliferation; Cells, Cultured; Cytochrome P-450 CYP1A1; Dihydroxydihydrobenzopyrenes; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Glutathione S-Transferase pi; Humans; Naphthalenes; Rats; Transgenes

2009
Monitoring dihydrodiol polyaromatic hydrocarbon metabolites produced by the freshwater microalgae Selenastrum capricornutum.
    Chemosphere, 2016, Volume: 158

    Topics: Benzo(a)pyrene; Biodegradation, Environmental; Biological Assay; Biomass; Chlorophyta; Chromatography, High Pressure Liquid; Environmental Monitoring; Fluorenes; Fresh Water; Microalgae; Naphthalenes; Polycyclic Aromatic Hydrocarbons; Reproducibility of Results; Water Microbiology

2016
Benzo(a)pyren-7,8-dihydrodiol-9,10-epoxide induces human trophoblast Swan 71 cell dysfunctions due to cell apoptosis through disorder of mitochondrial fission/fusion.
    Environmental pollution (Barking, Essex : 1987), 2018, Volume: 233

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Apoptosis; Benzo(a)pyrene; Carcinogens; Cell Line; Cytochromes c; Drosophila Proteins; Epoxy Compounds; Humans; Mitochondria; Mitochondrial Dynamics; Naphthalenes; Nerve Tissue Proteins; Nuclear Proteins; Toxicity Tests; Transcription Factors; Trophoblasts

2018
Benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide induces ferroptosis in neuroblastoma cells through redox imbalance.
    The Journal of toxicological sciences, 2022, Volume: 47, Issue:12

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzo(a)pyrene; Epoxy Compounds; Ferroptosis; Humans; Lipid Peroxides; Neuroblastoma; Neurotoxicity Syndromes; NF-E2-Related Factor 2; Oxidation-Reduction

2022