tranexamic acid has been researched along with pksi 527 in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (55.56) | 18.2507 |
| 2000's | 4 (22.22) | 29.6817 |
| 2010's | 4 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hijikata-Okunomiya, A; Okada, Y; Okamoto, S; Okamoto, U; Tsuda, Y; Wanaka, K | 1 |
| Hijikata-Okunomiya, A; Katsuura, Y; Okada, Y; Okamoto, S; Wanaka, K | 1 |
| Bohgaki, M; Hijikata-Okunomiya, A; Naito, T; Okada, Y; Okamoto, S; Wanaka, K | 1 |
| Fujimori, Y; Katsuura, Y; Nakamura, T; Okamoto, S; Shimizu, K; Wanaka, K; Yamamuro, T | 1 |
| Hijikata-Okunomiya, A; Okada, Y; Okamoto, S; Okamoto, U; Taguchi, H; Teno, N; Wanaka, K | 1 |
| Katsuura, Y; Ohno, N; Okamoto, S; Wanaka, K | 1 |
| Murakami, K; Okabe, H; Okada, Y; Okajima, K; Okamoto, S; Uchiba, M | 1 |
| Hijikata-Okunomiya, A; Okada, Y; Okamoto, S; Tada, M; Tsuda, Y; Wanaka, K | 1 |
| Hijikata-Okunomiya, A; Okada, Y; Okamoto, S; Okamoto, U; Tada, M; Tsuda, Y; Wanaka, K | 1 |
| Fukumizu, A; Hijikata-Okunomiya, A; Okada, Y; Okamoto, S; Tada, M; Tsuda, Y; Wanaka, K | 1 |
| Hijikata-Okunomiya, A; Ishida, T; Okada, Y; Okamoto, S; Satoh, K; Tomoo, K; Tsuda, Y; Wanaka, K | 1 |
| Giddings, JC; Hashimoto, M; Matsuo, O; Oiwa, K; Okada, K; Okada, Y; Okamoto, S; Ueshima, S; Yamamoto, J | 1 |
| Ikarugi, H; Inoue, A; Ishii, H; Okada, Y; Tsuda, Y; Yamamoto, J; Yamashita, T | 1 |
| Akira, T; Egi, Y; Maruyama, T; Matsumura, Y; Ohkita, M; Sasaoka, T; Takaoka, M; Tawa, M; Yamamoto, A | 1 |
| Halls, C; Jones, RG; Liu, Y; Longstaff, C; Matejtschuk, P; Sesardic, D; Thorpe, SJ | 1 |
| Gohda, K; Teno, N; Tsuda, Y; Wanaka, K | 1 |
| Li, S; Wang, F; Wang, H; Zha, W; Zhang, J; Zhu, Q | 1 |
| Huang, J; Liu, M; Yang, P; Zang, DD; Zhang, C; Zhang, JX; Zhu, QX | 1 |
18 other study(ies) available for tranexamic acid and pksi 527
| Article | Year |
|---|---|
Synthesis of trans-4-aminomethylcyclohexanecarbonyl-L- and -D-phenylalanine-4-carboxymethylanilide and examination of their inhibitory activity against plasma kallikrein.
Topics: Animals; Cattle; Humans; Kallikreins; Phenylalanine; Stereoisomerism; Tranexamic Acid | 1992 |
A finding of highly selective synthetic inhibitor of plasma kallikrein; its action to bradykinin generation, intrinsic coagulation and experimental DIC.
Topics: Animals; Blood Coagulation; Bradykinin; Disease Models, Animal; Disseminated Intravascular Coagulation; Endotoxins; Fibrinogen; Humans; In Vitro Techniques; Kallikreins; Kaolin; Kinetics; Mice; Partial Thromboplastin Time; Phenylalanine; Rats; Tranexamic Acid | 1992 |
Effect of a highly selective plasma-kallikrein synthetic inhibitor on contact activation relating to kinin generation, coagulation and fibrinolysis.
Topics: Blood Coagulation; Bradykinin; Carrageenan; Cyclohexanecarboxylic Acids; Fibrinolysis; Humans; Kallikreins; Kaolin; Kinetics; Phenylalanine; Tranexamic Acid | 1990 |
Effects of a highly selective plasma kallikrein inhibitor on collagen-induced arthritis in mice.
Topics: Animals; Arthritis, Experimental; Collagen; Indomethacin; Kallikreins; Kininogens; Male; Mice; Mice, Inbred DBA; Phenylalanine; Prekallikrein; Tranexamic Acid | 1993 |
Development of active center-directed plasmin and plasma kallikrein inhibitors and studies on the structure-inhibitory activity relationship.
Topics: Amino Acid Sequence; Amino Acids; Animals; Fibrinolysin; Humans; Kallikreins; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Phenylalanine; Structure-Activity Relationship; Tranexamic Acid; Tyrosine | 1993 |
Effects of a highly selective synthetic inhibitor of plasma kallikrein on disseminated intravascular coagulation in rats.
Topics: Animals; Blood Coagulation; Fibrin Fibrinogen Degradation Products; Fibrinogen; Infusions, Intravenous; Kallikreins; Male; Phenylalanine; Platelet Count; Rats; Rats, Sprague-Dawley; Serine Proteinase Inhibitors; Tranexamic Acid | 1996 |
Effects of plasma kallikrein specific inhibitor and active-site blocked factor VIIa on the pulmonary vascular injury induced by endotoxin in rats.
Topics: Amino Acid Chloromethyl Ketones; Animals; Binding Sites; Bronchoalveolar Lavage Fluid; Capillary Permeability; Dansyl Compounds; Disseminated Intravascular Coagulation; Endotoxemia; Endotoxins; Factor VIIa; Factor Xa Inhibitors; Kallikreins; Lung; Male; Phenylalanine; Pulmonary Artery; Pulmonary Veins; Rats; Rats, Wistar; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Specific Pathogen-Free Organisms; Tranexamic Acid | 1997 |
Design of plasma kallikrein inhibitors: functional and structural requirements of plasma kallikrein inhibitors.
Topics: Drug Design; Kallikreins; Phenylalanine; Serine Proteinase Inhibitors; Tranexamic Acid | 1998 |
Development of plasma kallikrein selective inhibitors.
Topics: Binding Sites; Drug Design; Fibrinolysin; Humans; Kallikreins; Kinetics; Molecular Structure; Oligopeptides; Phenylalanine; Serine Proteinase Inhibitors; Thrombin; Tranexamic Acid; Urokinase-Type Plasminogen Activator | 1999 |
Amino acids and peptides. LIII. Synthesis and biological activities of some pseudo-peptide analogs of PKSI-527, a plasma kallikrein selective inhibitor: the importance of the peptide backbone.
Topics: Animals; Fibrinolysin; Fibrinolytic Agents; Humans; Kallikreins; Phenylalanine; Plasminogen Activators; Serine Proteinase Inhibitors; Thrombin; Tranexamic Acid; Trypsin Inhibitors; Urokinase-Type Plasminogen Activator | 1999 |
Binding diversity of a noncovalent-type low-molecular-weight serine protease inhibitor and function of a catalytic water molecule: X-ray crystal structure of PKSI-527--inhibited trypsin.
Topics: Animals; Binding Sites; Catalysis; Cattle; Crystallography, X-Ray; Hydrogen Bonding; Models, Molecular; Molecular Weight; Phenylalanine; Protein Binding; Protein Conformation; Serine Proteinase Inhibitors; Tranexamic Acid; Trypsin; Water | 2001 |
Suppression of argatroban-induced endogenous thrombolysis by PKSI-527, and antibodies to TPA and UPA, evaluated in a rat arterial thrombolysis model.
Topics: Animals; Antibodies; Arginine; Drug Antagonism; Fibrinolysin; Fibrinolysis; Fibrinolytic Agents; Kallikreins; Male; Mesenteric Arteries; Phenylalanine; Pipecolic Acids; Plasma Kallikrein; Rats; Rats, Wistar; Sulfonamides; Thrombolytic Therapy; Thrombosis; Tissue Plasminogen Activator; Tranexamic Acid; Urokinase-Type Plasminogen Activator | 2003 |
Synergistic antithrombotic effect of a combination of NO donor and plasma kallikrein inhibitor.
Topics: Adult; Aged; Blood Platelets; Drug Synergism; Female; Fibrinolytic Agents; Humans; In Vitro Techniques; Kallikreins; Male; Middle Aged; Nitric Oxide Donors; Phenylalanine; S-Nitrosoglutathione; Thrombosis; Tranexamic Acid | 2005 |
Angiotensin II type 2 receptor-mediated inhibition of norepinephrine release in isolated rat hearts.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Bradykinin; Heart; Imidazoles; In Vitro Techniques; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Oligopeptides; Phenylalanine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sympathetic Nervous System; Tranexamic Acid; Vasoconstrictor Agents | 2008 |
Release of proteolytic activity following reduction in therapeutic human serum albumin containing products: detection with a new neoepitope endopeptidase immunoassay.
Topics: Albumins; Botulinum Toxins; Cysteine; Dose-Response Relationship, Drug; Endopeptidases; Epitopes; Humans; Immunoassay; Neurotoxins; Peptides; Phenylalanine; Serum Albumin; Synaptosomal-Associated Protein 25; Tissue Kallikreins; Tranexamic Acid; Zinc | 2011 |
Predicting subsite interactions of plasmin with substrates and inhibitors through computational docking analysis.
Topics: Computational Biology; Dipeptides; Dose-Response Relationship, Drug; Fibrinolysin; Models, Molecular; Molecular Structure; Oligopeptides; Phenylalanine; Serine Proteinase Inhibitors; Structure-Activity Relationship; Substrate Specificity; Tranexamic Acid | 2012 |
[Study on the expression of bradykinin and its receptors B1R and B2R in the kidney immune injury in trichloroethylene-sensitized mouse].
Topics: Administration, Cutaneous; Animals; Bradykinin; Kidney; Mice; Phenylalanine; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Solvents; Tranexamic Acid; Trichloroethylene | 2015 |
[Role of kallikrein kinin system activation in kidney injury induced by trichloroethylene sensitized mice].
Topics: Animals; Complement System Proteins; Female; Kallikrein-Kinin System; Kidney; Mice; Mice, Inbred BALB C; Phenylalanine; Solvents; Tranexamic Acid; Trichloroethylene | 2016 |