Page last updated: 2024-08-23

tramadol and ticlopidine

tramadol has been researched along with ticlopidine in 1 studies

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hagelberg, NM; Laine, K; Neuvonen, M; Neuvonen, PJ; Olkkola, KT; Saari, TI; Saarikoski, T; Scheinin, M; Turpeinen, M	1

Trials

1 trial(s) available for tramadol and ticlopidine

Article	Year
Ticlopidine inhibits both O-demethylation and renal clearance of tramadol, increasing the exposure to it, but itraconazole has no marked effect on the ticlopidine-tramadol interaction. European journal of clinical pharmacology, 2013, Volume: 69, Issue:4 Topics: Adult; Analgesics, Opioid; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cross-Over Studies; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; Humans; Itraconazole; Kidney; Male; Metabolic Clearance Rate; Oxidoreductases, N-Demethylating; Ticlopidine; Tramadol; Young Adult	2013

Article

Year

Ticlopidine inhibits both O-demethylation and renal clearance of tramadol, increasing the exposure to it, but itraconazole has no marked effect on the ticlopidine-tramadol interaction.

European journal of clinical pharmacology, 2013, Volume: 69, Issue:4

Topics: Adult; Analgesics, Opioid; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cross-Over Studies; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; Humans; Itraconazole; Kidney; Male; Metabolic Clearance Rate; Oxidoreductases, N-Demethylating; Ticlopidine; Tramadol; Young Adult

2013