Page last updated: 2024-08-23

tramadol and tapentadol

tramadol has been researched along with tapentadol in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (3.13)29.6817
2010's25 (78.13)24.3611
2020's6 (18.75)2.80

Authors

AuthorsStudies
Brockmöller, J; Friesacher, HR; Meyer, MJ; Neumann, VE; Tzvetkov, MV; Zdrazil, B1
Guay, DR1
Kadowitz, PJ; Nossaman, BD; Nossaman, VE; Ramadhyani, U1
Moyo, J; Rashiq, S1
Buschmann, H; Christoph, T; Eichenbaum, G; Englberger, W; Flores, CM; Hertrampf, T; Kögel, B; Raffa, RB; Schiene, K; Straßburger, W; Terlinden, R; Tzschentke, TM1
Glaser, PE; Rush, CR; Stoops, WW1
Kögel, B; Schneider, J; Terlinden, R1
Kanbara, T; Kanemasa, T; Minami, K; Nakamura, A; Ono, H; Sakaguchi, G; Shinohara, S1
Pergolizzi, JV; Raffa, RB; Smith, HS; Tallarida, RJ; Taylor, R1
Lehmann, U; Richter, U; Waldmann-Rex, S1
Bernardy, K; Häuser, W; Maier, C1
Chang, S; Mehta, V; Ramaswamy, S1
Fung, SM; Ho, RY; Kearney, TE; Tsutaoka, BT1
Dogan, C; Eerdekens, M; Etropolski, M; Karcher, K; Koch, ED; Kosturski, H; Kress, HG; Steup, A1
Barbosa, J; Carvalho, F; Dinis-Oliveira, RJ; Faria, J; Moreira, R; Queirós, O3
Crow, JM1
Gibbs, LM; Lindsay, TJ; Snyder, MJ1
Johnson-Davis, KL; Slawson, MH; Wu, F1
Afonso, LP; Barbosa, J; Carvalho, F; Dinis-Oliveira, RJ; Faria, J; Leal, S; Lobo, J; Moreira, R; Queirós, O2
Bang, D; Bordelon, GJ; Chang, D; Helander, EM; Hsu, D; Julka, I; Kai, A; Kaye, AD; Vadivelu, N1
Bell, RF; Derry, S; Moore, RA; Wee, B; Wiffen, PJ1
Cardona-Carballo, C; de la Casa-Resino, C; Guillén-Astete, CA1
Brás, M; Fragoso, M; Vieira, C1
Desmeules, J; Piguet, V; Rollason, V; Roulet, L2
Alam, U; Selvarajah, D; Sloan, G; Tesfaye, S1
Atayee, RS; Edmonds, KP; Wen, RY1
Buckley, NA; Chan, BS; Chiew, AL; Mirabella, J; Ravi, D1
Alshehri, FS1

Reviews

14 review(s) available for tramadol and tapentadol

ArticleYear
Is tapentadol an advance on tramadol?
    The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists, 2009, Volume: 24, Issue:11

    Topics: Adrenergic Uptake Inhibitors; Analgesics, Opioid; Animals; Clinical Trials as Topic; Humans; Pain; Phenols; Receptors, Opioid, mu; Tapentadol; Tramadol

2009
Advances in perioperative pain management: use of medications with dual analgesic mechanisms, tramadol & tapentadol.
    Anesthesiology clinics, 2010, Volume: 28, Issue:4

    Topics: Analgesics; Animals; Cytochrome P-450 CYP2D6; Humans; Injections, Spinal; Pain, Postoperative; Perioperative Care; Phenols; Receptors, Opioid, mu; Serotonin Syndrome; Tapentadol; Tramadol

2010
Mechanistic and functional differentiation of tapentadol and tramadol.
    Expert opinion on pharmacotherapy, 2012, Volume: 13, Issue:10

    Topics: Analgesics, Opioid; Animals; Humans; Pain; Phenols; Receptors, Opioid, mu; Tapentadol; Tramadol

2012
Combining opioid and adrenergic mechanisms for chronic pain.
    Postgraduate medicine, 2014, Volume: 126, Issue:4

    Topics: Analgesics, Opioid; Chronic Pain; Drug Combinations; Female; Humans; Middle Aged; Nociceptive Pain; Phenols; Selective Serotonin Reuptake Inhibitors; Tapentadol; Tramadol

2014
[Long-term opioid therapy in chronic noncancer pain. A systematic review and meta-analysis of efficacy, tolerability and safety in open-label extension trials with study duration of at least 26 weeks].
    Schmerz (Berlin, Germany), 2015, Volume: 29, Issue:1

    Topics: Analgesics, Opioid; Buprenorphine; Chronic Pain; Hydromorphone; Long-Term Care; Morphine; Oxycodone; Oxymorphone; Pain Measurement; Phenols; Randomized Controlled Trials as Topic; Tapentadol; Tramadol; Treatment Outcome

2015
Treating Painful Diabetic Peripheral Neuropathy: An Update.
    American family physician, 2016, Aug-01, Volume: 94, Issue:3

    Topics: Administration, Topical; Amines; Amitriptyline; Analgesics; Analgesics, Opioid; Anesthetics, Local; Capsaicin; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Isosorbide Dinitrate; Lidocaine; Phenols; Pregabalin; Selective Serotonin Reuptake Inhibitors; Sensory System Agents; Serotonin and Noradrenaline Reuptake Inhibitors; Tapentadol; Tramadol; Transcutaneous Electric Nerve Stimulation; Vasodilator Agents; Venlafaxine Hydrochloride

2016
Comparative metabolism of tramadol and tapentadol: a toxicological perspective.
    Drug metabolism reviews, 2016, Volume: 48, Issue:4

    Topics: Animals; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Membrane Transport Proteins; Metabolomics; Phenols; Tapentadol; Tramadol

2016
Ketorolac, Oxymorphone, Tapentadol, and Tramadol: A Comprehensive Review.
    Anesthesiology clinics, 2017, Volume: 35, Issue:2

    Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ketorolac; Oxymorphone; Pain; Pain Measurement; Phenols; Tapentadol; Tramadol

2017
Opioids for cancer pain - an overview of Cochrane reviews.
    The Cochrane database of systematic reviews, 2017, 07-06, Volume: 7

    Topics: Acetaminophen; Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Buprenorphine; Cancer Pain; Codeine; Fentanyl; Humans; Hydromorphone; Methadone; Oxycodone; Phenols; Review Literature as Topic; Tapentadol; Tramadol

2017
Comparative pharmacology and toxicology of tramadol and tapentadol.
    European journal of pain (London, England), 2018, Volume: 22, Issue:5

    Topics: Analgesics, Opioid; Humans; Pain; Quality of Life; Tapentadol; Tramadol

2018
[Opioids for Cancer Pain and its Use under Particular Conditions: A Narrative Review].
    Acta medica portuguesa, 2019, May-31, Volume: 32, Issue:5

    Topics: Administration, Oral; Analgesics, Opioid; Buprenorphine; Cancer Pain; Codeine; Deglutition Disorders; Fentanyl; Humans; Hydromorphone; Liver Failure; Morphine; Oxycodone; Renal Dialysis; Renal Insufficiency; Tapentadol; Tramadol

2019
Tapentadol Versus Tramadol: A Narrative and Comparative Review of Their Pharmacological, Efficacy and Safety Profiles in Adult Patients.
    Drugs, 2021, Volume: 81, Issue:11

    Topics: Analgesics, Opioid; Cytochrome P-450 CYP2D6; Dose-Response Relationship, Drug; Humans; Liver Failure; Pain; Renal Insufficiency; Tapentadol; Tramadol

2021
The Treatment of Painful Diabetic Neuropathy.
    Current diabetes reviews, 2022, Volume: 18, Issue:5

    Topics: Analgesics, Opioid; Diabetes Mellitus; Diabetic Neuropathies; Humans; Ligands; Pain; Quality of Life; Serotonin and Noradrenaline Reuptake Inhibitors; Tapentadol; Tramadol

2022
Tapentadol: A Review of Experimental Pharmacology Studies, Clinical Trials, and Recent Findings.
    Drug design, development and therapy, 2023, Volume: 17

    Topics: Analgesics; Analgesics, Opioid; Drug-Related Side Effects and Adverse Reactions; Humans; Neuralgia; Phenols; Tapentadol; Tramadol

2023

Trials

4 trial(s) available for tramadol and tapentadol

ArticleYear
Miotic and subject-rated effects of therapeutic doses of tapentadol, tramadol, and hydromorphone in occasional opioid users.
    Psychopharmacology, 2013, Volume: 228, Issue:2

    Topics: Administration, Oral; Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hydromorphone; Male; Miosis; Phenols; Pupil; Receptors, Opioid, mu; Tapentadol; Time Factors; Tramadol; Young Adult

2013
Characterisation of tramadol, morphine and tapentadol in an acute pain model in Beagle dogs.
    Veterinary anaesthesia and analgesia, 2014, Volume: 41, Issue:3

    Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Male; Morphine; Pain; Pain Measurement; Phenols; Receptors, Opioid, mu; Tapentadol; Tramadol

2014
[Conversion to tapentadol PR improves analgesia and quality of life in patients with severe and chronic pain despite using tramadol > 300 mg/d].
    Wiener klinische Wochenschrift, 2015, Volume: 127, Issue:11-12

    Topics: Aged; Analgesics, Opioid; Chronic Pain; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pain Measurement; Phenols; Quality of Life; Receptors, Opioid, mu; Tapentadol; Tramadol; Treatment Outcome

2015
Direct conversion from tramadol to tapentadol prolonged release for moderate to severe, chronic malignant tumour-related pain.
    European journal of pain (London, England), 2016, Volume: 20, Issue:9

    Topics: Aged; Analgesics, Opioid; Cancer Pain; Chronic Pain; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Middle Aged; Phenols; Tapentadol; Tramadol; Treatment Outcome

2016

Other Studies

14 other study(ies) available for tramadol and tapentadol

ArticleYear
Opioids as Substrates and Inhibitors of the Genetically Highly Variable Organic Cation Transporter OCT1.
    Journal of medicinal chemistry, 2019, 11-14, Volume: 62, Issue:21

    Topics: Analgesics, Opioid; HEK293 Cells; Humans; Inhibitory Concentration 50; Models, Molecular; Organic Cation Transporter 1; Permeability; Protein Conformation

2019
Perioperative considerations for "new" kids on the opioid block.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2011, Volume: 58, Issue:5

    Topics: Analgesics, Opioid; Buprenorphine; Humans; Pain; Perioperative Care; Phenols; Tapentadol; Tramadol

2011
Effect of the norepinephrine transporter (NET) inhibition on μ-opioid receptor (MOR)-induced anti-nociception in a bone cancer pain model.
    Journal of pharmacological sciences, 2014, Volume: 125, Issue:3

    Topics: Analgesics, Opioid; Animals; Bone Neoplasms; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice, Inbred C3H; Morphine; Neoplasm Transplantation; Norepinephrine Plasma Membrane Transport Proteins; Oxycodone; Pain; Phenols; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Tapentadol; Tramadol; Tumor Cells, Cultured

2014
Tapentadol--the evidence so far.
    Anaesthesia, 2015, Volume: 70, Issue:5

    Topics: Analgesics, Opioid; Clinical Trials as Topic; Evidence-Based Medicine; Guidelines as Topic; Humans; Peripheral Nervous System Diseases; Phenols; Tapentadol; Tramadol

2015
Comparative Toxicity of Tapentadol and Tramadol Utilizing Data Reported to the National Poison Data System.
    The Annals of pharmacotherapy, 2015, Volume: 49, Issue:12

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Analgesics, Opioid; Child; Child, Preschool; Drug Overdose; Female; Humans; Infant; Male; Middle Aged; Phenols; Poison Control Centers; Retrospective Studies; Risk; Seizures; Tapentadol; Tramadol; Vomiting; Young Adult

2015
Comparative study of the neurotoxicological effects of tramadol and tapentadol in SH-SY5Y cells.
    Toxicology, 2016, 06-01, Volume: 359-360

    Topics: Adenosine Triphosphate; Analgesics, Opioid; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Survival; Cytochromes c; Glucose; Humans; Lactic Acid; Membrane Potential, Mitochondrial; Necrosis; Phenols; Tapentadol; Thiobarbituric Acid Reactive Substances; Tramadol

2016
Biomedicine: Move over, morphine.
    Nature, 2016, 07-14, Volume: 535, Issue:7611

    Topics: Acute Pain; Adult; Chronic Pain; Drug Tolerance; Early Medical Intervention; Humans; Male; Morphine; Morphine Derivatives; Neural Inhibition; Oligopeptides; Opioid-Related Disorders; Pain Management; Peptides, Cyclic; Phenols; Receptors, Opioid, mu; Spinal Cord Stimulation; Tapentadol; Tramadol; Young Adult

2016
Metabolic Patterns of Fentanyl, Meperidine, Methylphenidate, Tapentadol and Tramadol Observed in Urine, Serum or Plasma.
    Journal of analytical toxicology, 2017, May-01, Volume: 41, Issue:4

    Topics: Analgesics, Opioid; Fentanyl; Humans; Meperidine; Methylphenidate; Phenols; Plasma; Prescription Drugs; Substance Abuse Detection; Tapentadol; Tramadol

2017
Effective analgesic doses of tramadol or tapentadol induce brain, lung and heart toxicity in Wistar rats.
    Toxicology, 2017, 06-15, Volume: 385

    Topics: Alanine Transaminase; Analgesics, Opioid; Animals; Aspartate Aminotransferases; Blood Glucose; Brain; Caspase 3; Creatine Kinase; Heart; L-Lactate Dehydrogenase; Lactic Acid; Lipid Peroxidation; Lung; Male; Myocardium; Phenols; Protein Carbonylation; Rats, Wistar; Tapentadol; Tramadol

2017
Acute administration of tramadol and tapentadol at effective analgesic and maximum tolerated doses causes hepato- and nephrotoxic effects in Wistar rats.
    Toxicology, 2017, 08-15, Volume: 389

    Topics: Analgesics, Opioid; Animals; Biomarkers; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Injections, Intraperitoneal; Kidney; Kidney Diseases; Liver; Male; Maximum Tolerated Dose; Oxidative Stress; Phenols; Proteinuria; Rats, Wistar; Risk Assessment; Tapentadol; Time Factors; Tramadol

2017
Tapentadol versus tramadol in the management of low back pain in the emergency department: Impact of use on the need for reassessments.
    Medicine, 2017, Volume: 96, Issue:45

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Emergency Service, Hospital; Female; Humans; Low Back Pain; Male; Middle Aged; Odds Ratio; Phenols; Retrospective Studies; Tapentadol; Tramadol

2017
[Monoaminergic opioids: which one should we choose?]
    Revue medicale suisse, 2021, Jun-23, Volume: 17, Issue:744

    Topics: Analgesics, Opioid; Chronic Pain; Constipation; Humans; Tapentadol; Tramadol

2021
A Comparison of Institutional Opioid Equianalgesia Tools: A National Study.
    Journal of palliative medicine, 2022, Volume: 25, Issue:11

    Topics: Administration, Oral; Analgesics, Opioid; Fentanyl; Humans; Hydrocodone; Hydromorphone; Levorphanol; Morphine; Oxycodone; Tapentadol; Tramadol

2022
Prescribing trend of tapentadol in a Sydney local health district.
    British journal of clinical pharmacology, 2022, Volume: 88, Issue:9

    Topics: Analgesics, Opioid; Australia; Delayed-Action Preparations; Humans; Morphine; Oxycodone; Pain, Postoperative; Phenols; Tapentadol; Tramadol

2022