Compounds > tramadol
Page last updated: 2024-08-23

tramadol and quinidine

tramadol has been researched along with quinidine in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Collart, L; Dayer, P; Favario-Constantin, C; Luthy, C1
Hou, YN; Liu, CS; Liu, HC; Wang, N1
Guo, B; He, MM; Li, C; Liu, H; Shen, H; Wang, L; Wrighton, SA1
Raffa, RB; Stone, DJ1
Cui, D; Liu, S; Lu, J; Mi, L; Qian, J; Xu, X1
Benzi, JRL; de Moraes, NV; Godoy, ALPC; Lanchote, VL1
Cicali, B; Cristofoletti, R; Dow, P; Long, T; Michaud, V; Schmidt, S; Turgeon, J1

Trials

1 trial(s) available for tramadol and quinidine

ArticleYear
[Duality of the analgesic effect of tramadol in humans].
    Schweizerische medizinische Wochenschrift, 1993, Nov-27, Volume: 123, Issue:47

    Topics: Adult; Double-Blind Method; Humans; Male; Naloxone; Pupil; Quinidine; Reflex; Tramadol

1993

Other Studies

6 other study(ies) available for tramadol and quinidine

ArticleYear
[Stereoselectivity in O-demethylation of trans tramadol in rat liver microsomes in vitro].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2002, Volume: 37, Issue:3

    Topics: Analgesics, Opioid; Animals; Cell Separation; Male; Microsomes, Liver; Quinidine; Quinine; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tramadol

2002
Comparative metabolic capabilities and inhibitory profiles of CYP2D6.1, CYP2D6.10, and CYP2D6.17.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:8

    Topics: Atomoxetine Hydrochloride; Cocaine; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Debrisoquin; Dextromethorphan; Enzyme Inhibitors; Ethanolamines; Fluoxetine; Humans; Hydroxylation; Imipramine; Kinetics; Microsomes; Molecular Structure; Nortriptyline; Polymorphism, Single Nucleotide; Propylamines; Quinidine; Recombinant Proteins; Thioridazine; Tramadol

2007
Unexceptional seizure potential of tramadol or its enantiomers or metabolites in mice.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 325, Issue:2

    Topics: Analgesics, Opioid; Animals; Codeine; Cytochrome P-450 CYP2D6 Inhibitors; Drug Interactions; Hot Temperature; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Narcotic Antagonists; Oxycodone; Pain; Quinidine; Reserpine; Seizures; Stereoisomerism; Tramadol

2008
Nanocomposites of graphene and cytochrome P450 2D6 isozyme for electrochemical-driven tramadol metabolism.
    Langmuir : the ACS journal of surfaces and colloids, 2014, Oct-07, Volume: 30, Issue:39

    Topics: Biocatalysis; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Electrochemistry; Electrodes; Electron Transport; Enzymes, Immobilized; Graphite; Isoenzymes; Models, Molecular; Nanocomposites; Polyethyleneimine; Protein Conformation; Quinidine; Tramadol

2014
Changes in tramadol enantioselective pharmacokinetics and metabolism in rats with experimental diabetes treated or not with insulin.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2019, Feb-01, Volume: 128

    Topics: Analgesics, Opioid; Animals; Area Under Curve; Blood Glucose; Diabetes Mellitus, Experimental; Gene Expression Regulation; Insulin; Male; Quinidine; Rats; Rats, Wistar; Tramadol

2019
Physiologically Based Pharmacokinetic Modeling to Assess the Impact of CYP2D6-Mediated Drug-Drug Interactions on Tramadol and O-Desmethyltramadol Exposures via Allosteric and Competitive Inhibition.
    Journal of clinical pharmacology, 2022, Volume: 62, Issue:1

    Topics: Analgesics, Opioid; Area Under Curve; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Drug Interactions; Half-Life; Humans; Metabolic Clearance Rate; Metoprolol; Models, Biological; Quinidine; Tramadol

2022