Page last updated: 2024-08-23

tramadol and dextromethorphan

tramadol has been researched along with dextromethorphan in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (35.71)29.6817
2010's7 (50.00)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Brockmöller, J; Friesacher, HR; Meyer, MJ; Neumann, VE; Tzvetkov, MV; Zdrazil, B1
Abdel-Rahman, SM; Gaedigk, A; Gotschall, RR; Kearns, GL; Leeder, JS; Liao, S; Medve, R; Spielberg, SP; Wilson, JT1
Hou, YN; Liu, HC; Wang, N; Yu, Y1
Abdel-Rahman, SM; Alander, SW; Bhathena, A; Bradford, LD; Gaedigk, A; Leeder, JS; Ndjountché, L; Pearce, RE; Rogan, PK1
Guo, B; He, MM; Li, C; Liu, H; Shen, H; Wang, L; Wrighton, SA1
Ali, SM; Shahrbano, S; Ulhaq, TS1
Mullins, ME; Rengarajan, A1
El-Kady, E; El-Sadek, M; Heneedak, HM; Mostafa, S; Salama, I1
Zhang, N1
Allegaert, K; Annaert, P; Boussery, K; De Bock, L; Mannens, G; Snoeys, J; T'jollyn, H; Van Bocxlaer, J; Van Peer, A; Vermeulen, A1
Daali, Y; Desmeules, J; Lenglet, S; Matthey, A; Storelli, F; Thomas, A1
Bertol, E; D'Errico, S; Fais, P; Furlanetto, S; Palumbo, D; Pascali, JP; Pigaiani, N; Vaiano, F1
Hardy, M; Panikkar, G1
Ali, E; Aljazzar, SO; Alrbyawi, H; Alzahrani, E; Dera, AA; Elkaeed, EB; Farouk, AE; Iqbal, MM; Iqbal, S; Javed, M; Pashameah, RA; Yasien, S1

Trials

1 trial(s) available for tramadol and dextromethorphan

ArticleYear
Tramadol for pain relief in children undergoing adenotonsillectomy: a comparison with dextromethorphan.
    The Laryngoscope, 2008, Volume: 118, Issue:9

    Topics: Adenoidectomy; Administration, Oral; Analgesics, Opioid; Child; Child, Preschool; Dextromethorphan; Dose-Response Relationship, Drug; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Follow-Up Studies; Humans; Injections, Intravenous; Male; Pain Measurement; Pain, Postoperative; Prospective Studies; Tonsillectomy; Tramadol; Treatment Outcome

2008

Other Studies

13 other study(ies) available for tramadol and dextromethorphan

ArticleYear
Opioids as Substrates and Inhibitors of the Genetically Highly Variable Organic Cation Transporter OCT1.
    Journal of medicinal chemistry, 2019, 11-14, Volume: 62, Issue:21

    Topics: Analgesics, Opioid; HEK293 Cells; Humans; Inhibitory Concentration 50; Models, Molecular; Organic Cation Transporter 1; Permeability; Protein Conformation

2019
Concordance between tramadol and dextromethorphan parent/metabolite ratios: the influence of CYP2D6 and non-CYP2D6 pathways on biotransformation.
    Journal of clinical pharmacology, 2002, Volume: 42, Issue:1

    Topics: Adolescent; Analgesics, Opioid; Area Under Curve; Biotransformation; Child; Cytochrome P-450 CYP2D6; Dextromethorphan; Excitatory Amino Acid Antagonists; Humans; Least-Squares Analysis; Pilot Projects; Tramadol

2002
Stereoselectivity in trans-tramadol metabolism and trans-O-demethyltramadol formation in rat liver microsomes.
    Acta pharmacologica Sinica, 2003, Volume: 24, Issue:1

    Topics: Analgesics, Opioid; Animals; Dextromethorphan; Fluoxetine; Male; Microsomes, Liver; Propafenone; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tramadol

2003
Identification and characterization of novel sequence variations in the cytochrome P4502D6 (CYP2D6) gene in African Americans.
    The pharmacogenomics journal, 2005, Volume: 5, Issue:3

    Topics: Alleles; Black or African American; Cloning, Molecular; Cytochrome P-450 CYP2D6; Dextromethorphan; Ethanolamines; Female; Gene Expression; Gene Frequency; Genes, Reporter; Genetic Variation; Genotype; Haplotypes; Humans; Liver; Luciferases; Phenotype; Polymorphism, Single Nucleotide; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA Splicing; Tramadol; Transcription, Genetic

2005
Comparative metabolic capabilities and inhibitory profiles of CYP2D6.1, CYP2D6.10, and CYP2D6.17.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:8

    Topics: Atomoxetine Hydrochloride; Cocaine; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Debrisoquin; Dextromethorphan; Enzyme Inhibitors; Ethanolamines; Fluoxetine; Humans; Hydroxylation; Imipramine; Kinetics; Microsomes; Molecular Structure; Nortriptyline; Polymorphism, Single Nucleotide; Propylamines; Quinidine; Recombinant Proteins; Thioridazine; Tramadol

2007
How often do false-positive phencyclidine urine screens occur with use of common medications?
    Clinical toxicology (Philadelphia, Pa.), 2013, Volume: 51, Issue:6

    Topics: Alprazolam; Carbazoles; Carvedilol; Clonazepam; Dextromethorphan; Diphenhydramine; Drug Interactions; False Positive Reactions; Gas Chromatography-Mass Spectrometry; Humans; Phencyclidine; Propanolamines; Retrospective Studies; Substance-Related Disorders; Tramadol

2013
Development and validation of a sensitive UHPLC-MS/MS method for the simultaneous analysis of tramadol, dextromethorphan chlorpheniramine and their major metabolites in human plasma in forensic context: application to pharmacokinetics.
    Biomedical chromatography : BMC, 2015, Volume: 29, Issue:7

    Topics: Chlorpheniramine; Chromatography, High Pressure Liquid; Dextromethorphan; Drug Stability; Humans; Limit of Detection; Linear Models; Reproducibility of Results; Tandem Mass Spectrometry; Tramadol

2015
Letter to the editor regarding 'Development and validation of a sensitive UHPLC-MS/MS method for simultaneous analysis of tramadol, dextromethorphan chlorpheniramine and their major metabolites in human plasma in forensic context: application to pharmacok
    Biomedical chromatography : BMC, 2016, Volume: 30, Issue:4

    Topics: Chlorpheniramine; Chromatography, High Pressure Liquid; Dextromethorphan; Humans; Tandem Mass Spectrometry; Tramadol

2016
Strategies for Determining Correct Cytochrome P450 Contributions in Hepatic Clearance Predictions: In Vitro-In Vivo Extrapolation as Modelling Approach and Tramadol as Proof-of Concept Compound.
    European journal of drug metabolism and pharmacokinetics, 2017, Volume: 42, Issue:3

    Topics: Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Dextromethorphan; Humans; Kinetics; Liver; Metabolic Clearance Rate; Microsomes, Liver; Midazolam; Tramadol

2017
Impact of CYP2D6 Functional Allelic Variations on Phenoconversion and Drug-Drug Interactions.
    Clinical pharmacology and therapeutics, 2018, Volume: 104, Issue:1

    Topics: Adolescent; Adult; Alleles; Analgesics, Opioid; Antitussive Agents; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Dextromethorphan; Drug Interactions; Duloxetine Hydrochloride; Female; Genotype; Heterozygote; Homozygote; Humans; Male; Paroxetine; Pharmacogenomic Variants; Phenotype; Tramadol; Young Adult

2018
Internet pseudoscience: Testing opioid containing formulations with tampering potential.
    Journal of pharmaceutical and biomedical analysis, 2018, May-10, Volume: 153

    Topics: Acetaminophen; Analgesics, Opioid; Chemistry, Pharmaceutical; Chromatography, Liquid; Codeine; Dextromethorphan; Internet; Tablets; Tandem Mass Spectrometry; Tramadol

2018
A Case of Serotonin Syndrome in the Setting of Dextromethorphan-Based Cough Medicine, Tramadol, and Multiple Antidepressants.
    The primary care companion for CNS disorders, 2020, 03-05, Volume: 22, Issue:2

    Topics: Aged; Analgesics, Opioid; Antitussive Agents; Dextromethorphan; Female; Humans; Serotonin Agents; Serotonin Syndrome; Tramadol

2020
Simultaneous Quantification of Opioids in Blood and Urine by Gas Chromatography-Mass Spectrometer with Modified Dispersive Solid-Phase Extraction Technique.
    Molecules (Basel, Switzerland), 2022, Oct-10, Volume: 27, Issue:19

    Topics: Acetonitriles; Analgesics, Opioid; Codeine; Dextromethorphan; Gas Chromatography-Mass Spectrometry; Humans; Morphine; Morphine Derivatives; Nalbuphine; Solid Phase Extraction; Solvents; Substance Abuse Detection; Tramadol

2022