Page last updated: 2024-08-23

tramadol and codeine

tramadol has been researched along with codeine in 170 studies

Research

Studies (170)

TimeframeStudies, this research(%)All Research%
pre-19903 (1.76)18.7374
1990's19 (11.18)18.2507
2000's32 (18.82)29.6817
2010's72 (42.35)24.3611
2020's44 (25.88)2.80

Authors

AuthorsStudies
Brockmöller, J; Friesacher, HR; Meyer, MJ; Neumann, VE; Tzvetkov, MV; Zdrazil, B1
Szekely, SM; Vickers, MD1
Korpás, J; Nosál'ová, G; Strapková, A1
Jakovlev, V; Nickel, B; Szelenyi, I1
Aledter, A; Nickel, B1
Friderichs, E; Hennies, HH; Schneider, J1
Bernatzky, G; Jurna, I1
Breivik, H; Grimstad, J; Stubhaug, A1
Hepper, M; Hummel, T; Kobal, G; Kraetsch, HG; Liefhold, J; Lötsch, J1
Olligs, J1
Brown, K; Knight, LC; Krevsky, B; Maurer, AH1
McQuay, JH; Moore, AR1
Collart, L; Dayer, P; Desmeules, J1
Crighton, IM; Hobbs, GJ; Wrench, IJ1
Alvarez Requejo, A; Caro-Patón, T; Carvajal, A; García del Pozo, J; Martín Arias, LH; Martín de Diego, I; Rueda, AM1
Bakos, L; Crout, RJ; Graves, RW; Jackson, DL; Moore, PA; Schneider, LG1
Cobby, TF; Crighton, IM; Fletcher, AJ; Hobbs, GJ; Martin, PH; Stewart, PD1
Djian, MC; Donnadieu, S1
McQuay, HJ; Moore, RA1
Moore, PA1
Pluim, MA; Rupreht, J; Vulto, AG; Wegener, JT1
Charlton, P; Jeffrey, HM; Mellor, DJ; Moss, E; Vucevic, M1
Coulthard, P; Dobson, M; Pleuvry, BJ; Price, M1
Arcuri, E; Centulio, F; Ciocca, F; D'Angiolino, G; Ginobbi, P; Marcelli, ME; Pelagalli, L; Tirelli, W1
Hill, L; Kalla, A; Spargo, K; Wilder-Smith, CH1
Lacy, JR; Mullican, WS1
Benítez Del Rosario, MA; Cabrejas Sánchez, A; Fernández Díaz, R; Pérez Suárez, MC1
Becker, D; Phero, JC1
Cobby, TF; Crighton, IM; Fletcher, AJP; Hobbs, GJ; Knaggs, RD1
Cha, IH; Jung, YS; Kim, DK; Kim, HJ; Kim, MK; Lee, EW1
Laine, K; Tirkkonen, T1
Brunelli, C; De Conno, F; Ripamonti, C1
Sachdeva, DK; Stadnyk, JM1
Abolin, C; Hewitt, MC; Koch, P; Shao, L; Varney, M1
Dubray, C; Estrade, M; Pickering, G1
Bourne, MH; Jordan, D; Kamin, M; Rosenthal, NR; Xiang, J1
Bachmann, MS; Kairaluoma, PM; Pere, PJ; Rosenberg, PH1
Bertin, P1
Bravo, LE; Castillo, JM; Castillo, MP; Castro, F; Daza, P; Montoya, O; Restrepo, JM; Rodriguez, MF; Rodriguez, RF1
Guo, B; He, MM; Li, C; Liu, H; Shen, H; Wang, L; Wrighton, SA1
Ateleanu, B; Hall, JE; Logan, SW; Sudheer, PS; Terblanche, C1
Stamer, UM; Stüber, F2
Raffa, RB; Stone, DJ1
Adam, F1
Bachs, LC; Engeland, A; Mørland, JG; Skurtveit, S1
Berrocoso, E; Mico, JA1
Calon, B; Collange, O; Pottecher, T; Pourtalès, MC; Ravaz, T; Samin, J1
Lapeyre-Mestre, M; Montastruc, JL; Sommet, A; Tavassoli, N1
Boquete, M; Carballada, F; Carballas, C; Orjales, RN1
Gallagher, AM; Leighton-Scott, J; van Staa, TP1
Bertens, D; Dorhout Mees, SM; Rinkel, GJ; van den Bergh, WM; van der Worp, HB1
Barroso, M; Dias, M; López-Rivadulla, M; Queiroz, JA; Vieira, DN1
Barbaud, A; Schmutz, JL; Trechot, P1
Fantoni, DT; Kahvegian, MA; Leon-Román, MA; Martins, TL; Noel-Morgan, J; Otsuki, DA1
Leppert, W; Majkowicz, M1
Leppert, W; Mikolajczak, P1
Garneau, K; Glynn, RJ; Lee, J; Levin, R; Rassen, JA; Schneeweiss, S; Solomon, DH1
Dubin, RE1
Davidson, AJ; Palmer, GM; Teo, JH1
Alfano, G; Forino, A; Grieco, M; Iannotti, M; Meglio, G; Pace, MC1
Auerbach, AD; Maselli, JH; Rosenbluth, G; Wilson, SD1
Kim, MH; Park, EC; Park, H; Park, K1
Drudi, F; Maltoni, M; Rosati, M; Sartori, S; Tassinari, D; Tombesi, P1
Kahan, M; Mailis-Gagnon, A; Srivastava, A; Wilson, L1
Cobianchi, MR; Colini Baldeschi, G1
Häkkinen, M; Launiainen, T; Ojanperä, I; Vuori, E1
Auriche, P; Bourne, C; Daveluy, A; Descotes, J; Gouraud, A; Grandvuillemin, A; Vial, T1
Babalonis, S; Lofwall, MR; Nuzzo, PA; Siegel, AJ; Walsh, SL1
Bertin, P; Taieb, C1
Davey, J1
Ismail, R; Zahari, Z1
Ahmedzai, SH; Boland, JW; Foulds, GA; Pockley, AG1
Chatterton, C; Kintz, P1
Laflamme, L; Möller, J; Söderberg Löfdal, K1
Barbi, E; Calligaris, L; Marzuillo, P1
dePont Christensen, R; Gagne, JJ; Hallas, J; Larsen, TB; Pottegård, A; Wang, SV1
Chavoshi, S; Chevalier, P; LoCasale, R; Smulders, M; Sostek, M1
Azoulay, L; Fournier, JP; Montastruc, JL; Nessim, SJ; Yin, H1
Azoulay, L; Fournier, JP; Montastruc, JL; Suissa, S; Yin, H1
Higashi, T; Iwamoto, M; Kawaguchi, T; Matoba, M; Miura, H; Tanaka, S; Yamashita, I; Yoshida, S; Yoshimoto, T1
Akkaya, T; Ergil, J; Gülöksüz, ÇT; Peker, K; Polat, R1
Caraballo, PJ; Nicholson, WT; Rohrer Vitek, CR; Schultz, C1
Basedow, M; Esterman, A; Runciman, WB; Shanahan, EM; Williams, H1
Forrester, MB; Haynes, A; Kleinschmidt, K; Young, A1
Conaghan, PG; Dickerson, S; Junor, R; McSkimming, P; Serpell, M1
Dalen, I; Eide, GE; Lid, TG; Meland, E1
Cunha, RR; Muñoz, RAA; Ribeiro, MMAC; Richter, EM1
Karaman, E; Karaman, H; Tokgoz, O; Tufek, A1
Baker, O; Garner, C; Nelson, LS; Poon, SJ; Rodgers, AF; Schuur, JD; Weiner, SG1
Bell, RF; Derry, S; Moore, RA; Wee, B; Wiffen, PJ1
Anderson, BJ; Chalkiadis, GA; Ottaway, K; Thomas, J1
Aschenbrenner, DS1
Jin, J1
Islur, A; Izadpanah, A; Peters, B1
Bernhardt, MB; Chumpitazi, CE; Fox, KA; Glover, C; Hagan, JL; Patel, N; Taylor, RS1
Broome, ME; Carpenter, JS; Draucker, CB; Holmes, AM; Knisely, MR; Skaar, T; Von Ah, D1
Robinson-Lane, SG; Vallerand, AH1
Bertol, E; D'Errico, S; Fais, P; Furlanetto, S; Palumbo, D; Pascali, JP; Pigaiani, N; Vaiano, F1
Aubrun, F; Belhassen, M; Chrétien, E; Cornu, C; Ecoffey, C; Ginoux, M; Van Ganse, E1
Ekelin, E; Hansson, A1
Cavallari, LH; Elsey, AR; Schmidt, SO; Smith, DM; Weitzel, KW1
Bennett, K; Byrne, CJ; Cahir, C; Ryan, C; Walsh, C; Williams, DJ1
Ashkezari, MD; Farahmand, B; Mohammadpour, A; Shokrzadeh, M1
Ardid, D; Authier, N; Chenaf, C; Delage, N; Delorme, J; Eschalier, A; Kaboré, JL; Mulliez, A; Pereira, B; Zenut, M1
Benevent, J; Chebane, L; Durrieu, G; Montastruc, F; Montastruc, JL; Rousseau, V; Sommet, A1
Bouillet, L; Gibod, IB; Greco, C; Khouri, C; Lepelley, M; Pralong, P; Rossignol, J1
Baldacchino, A; Balfour, DJ; Matthews, K; Tolomeo, S1
Crowder, J; Fortenberry, M; So, TY1
Saggese, NP1
D'Alton, ME; Duffy, CR; Friedman, AM; Kern-Goldberger, AR; Landau, R; Mourad, M; Siddiq, Z; Wright, JD1
Agüera, A; Campos-Mañas, MC; Ferrer, I; Sánchez Pérez, JA; Thurman, EM1
Decker, BS; Desta, Z; Dexter, PR; Eadon, MT; Fulton, CR; Gufford, BT; Holmes, AM; Levy, KD; Pratt, VM; Rosenman, MB; Skaar, TC; T Callaghan, J; Zang, Y; Zhang, Y1
Choi, HK; Dubreuil, M; LaRochelle, MR; Lei, G; Lu, N; Wei, J; Zeng, C; Zhang, Y1
Dormuth, CR; Gomes, T; Juurlink, DN; Mamdani, MM; Morrow, RL; Paterson, M1
Andersson, ML; Bilén, K; Broström, O; Järnbert-Pettersson, H; Lindh, JD; Mannheimer, B1
Brás, M; Fragoso, M; Vieira, C1
Calissendorff, J; Falhammar, H; Lindh, JD; Mannheimer, B; Nathanson, D; Skov, J1
Abreu, MHNG; Lino, PA; Martins, MAP; Silva, MESE; Singhal, A; Sohn, W1
Bell, J; Buckley, NA; Collins, J; Nassar, N; Nielsen, TC; Paget, SP; Pearson, SA1
Choi, HK; Dubreuil, M; LaRochelle, MR; Lei, G; Lin, J; Lu, N; Tomasson, G; Wei, J; Wood, MJ; Zeng, C; Zhang, Y1
Abrams, R; Ambardekar, A; Kandil, E; Khan, A; Minhajuddin, A; Parikh, M; Williams, T1
Fernandez, I; Klahs, KJ; Nguyen, MP; Reich, MS1
Johansen, SS; Linnet, K; Nedahl, M1
Ajayi, AI; Somefun, OD1
Batistaki, C; Chrona, E; Gazouli, M; Kostopanagiotou, G; Kostroglou, A1
Cartmill, RS; Kalbfell, E; Kohler, JE; Schumacher, J1
Apollonio, DE; Lewis, J; Nguyen, KC; Phan, C; Quindoy, M; Wu, A1
Black, JC; Dart, RC; Iwanicki, JL; May, KP; Schwarz, J1
Grucza, R; Salas, J; Scherrer, JF; Tucker, J; Zhang, Z2
Buunk, AM; de Boer-Veger, NJ; Deneer, VHM; Guchelaar, HJ; Houwink, EJF; Matic, M; Mulder, H; Nijenhuis, M; Rongen, GAPJM; Soree, B; Swen, JJ; van Schaik, RHN; Weide, JV; Wilffert, B1
Berecki-Gisolf, J; Hayman, J; Lam, T; Lubman, DI; Nielsen, S; Sanfilippo, P1
Cuypers, E; Pajk, S; Van de Voorde, W; Van Den Bogaert, W; Vandenbosch, M; Wuestenbergs, J1
Hu, TX; Kim, J; Lin, AY; Livhits, MJ; Nguyen, DT; Schumm, MA; Tseng, CH; Wu, JX; Yeh, MW; Zhu, CY1
Azoulay, L; Filion, KB; Grad, R; Ou, LB; Platt, RW; Reynier, P; Yoon, S1
Carbonell-Abella, C; Collins, GS; Delmestri, A; Diez-Perez, A; Englund, M; Khalid, S; Martinez-Laguna, D; Nogues, X; Prieto-Alhambra, D; Reyes, C; Strauss, VY; Tadrous, M; Turkiewicz, A; Xie, J1
Kim, HS; Lank, PM; McCarthy, DM1
Authier, N; Chenaf, C; Choufi, S; Delorme, J; Merlin, E; Mounier, S; Rochette, E1
Prieto-Alhambra, D; Reyes, C; Xie, J1
Lee, YH; Shu, HY; Wei, J1
Chen, CH; Lai, CC; Wang, CY1
Ding, X; Li, X; Lu, N; Wang, Y; Wu, Z1
Aviña-Zubieta, JA; Cibere, J; Esdaile, JM; Kopec, JA; Li, L; Lu, N; Marozoff, S; Xie, H1
He, H; Li, W; Wu, Z; Xie, D; Yang, Z1
Coulter, C; Garnier, M; Moore, C1
Aldy, K; Brent, J; Calello, DP; Jefri, M; Krotulski, A; Logan, B; Manini, AF; Nguyen, TT; Walton, S; Wax, P1
Calip, GS; Evans, CT; Gellad, WF; Hubbard, CC; Lee, TA; McGregor, JC; Rowan, SA; Sharp, LK; Suda, KJ; Yan, CH1
Chau, A; Krausz, MR; Maclure, M; Nabavi, N; Polderman, S; Preston, R; Schwarz, SKW; Ziafat, K1
Ali, SR; Fife, D; Rijnbeek, PR; Schuemie, MJ; Singh, A; Voss, EA1
Abosi, AJ; Awogbindin, IO; Eneanya, SU; Folarin, OR; Ishola, IO; Okubadejo, NU; Olopade, JO1
Asiyanbola, B; Baye, JF; Blake, KV; Bronson, WH; Cavallari, LH; Chakraborty, H; Cicali, E; Cook, KJ; Dexter, PR; Elwood, EN; Fillingim, RB; Gong, Y; Gray, CF; Hines, L; Horowitz, CR; Johnson, JA; Kannry, J; Kucher, N; Lynch, S; Myers, RA; Nguyen, KA; Obeng, AO; Orlando, LA; Parvataneni, HK; Peterson, JF; Pratt, VM; Prieto, HA; Ramos, M; Rosenman, M; Sadeghpour, A; Singh, R; Skaar, TC; Starostik, P; Thomas, CD; Tillman, E; Van Driest, SL; Volpi, S; Voora, D; Wiisanen, K1
Philip, J; Rubio, J; Somogyi, AA; Wong, AK1
Bateman, BT; Esposito, DB; Hernández-Díaz, S; Huybrechts, KF; Mogun, H; Straub, L; Werler, MM1
Ali, E; Aljazzar, SO; Alrbyawi, H; Alzahrani, E; Dera, AA; Elkaeed, EB; Farouk, AE; Iqbal, MM; Iqbal, S; Javed, M; Pashameah, RA; Yasien, S1
Cerdá, M; Jent, V; Renny, MH; Townsend, T1
Bamidele, R; Enya, JI; Feyisike Johnson, O; Hamzat, EO; Johnson, BS; Olanrewaju, I; Olanrewaju, JA; Osuoya, Q; Owolabi, JO; Udekwu, MO1
Fouilhé Sam-Laï, N; Jouanjus, E; Khouri, C; Revol, B; Robert, M1
Habibollahi, S; Salamat, A; Soltani, N1
Caré, W; Dufayet, L; Langrand, J; Micallef, J; Pinel, S; Vodovar, D1
Jia, L; Tan, HL; Veldkamp, MW; Verkerk, AO1
Albertsen, TL; Bliddal, M; Broe, A; Damkier, P; Ibsen, IO; Nohr, EA; Rausgaard, NLK; Ravn, P1
Alvarez-Mon, M; Alvarez-Mon, MA; Carabot, F; Donat-Vargas, C; Fraile-Martínez, O; García-Montero, C; Monserrat, J; Ortega, MA; Santoma-Vilaclara, J; Zaragoza, C1

Reviews

17 review(s) available for tramadol and codeine

ArticleYear
Single-patient data meta-analysis of 3453 postoperative patients: oral tramadol versus placebo, codeine and combination analgesics.
    Pain, 1997, Volume: 69, Issue:3

    Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Codeine; Dextropropoxyphene; Double-Blind Method; Drug Therapy, Combination; Humans; Middle Aged; Pain, Postoperative; Randomized Controlled Trials as Topic; Risk Assessment; Tramadol; Treatment Outcome

1997
[Pharmacology of tramadol].
    Drugs, 1997, Volume: 53 Suppl 2

    Topics: Administration, Oral; Administration, Rectal; Analgesics, Opioid; Animals; Codeine; Humans; Injections, Intramuscular; Injections, Intravenous; Structure-Activity Relationship; Tramadol

1997
Postoperative analgesia and vomiting, with special reference to day-case surgery: a systematic review.
    Health technology assessment (Winchester, England), 1998, Volume: 2, Issue:12

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Codeine; Dextropropoxyphene; Diclofenac; Humans; Ibuprofen; Morphine; Ondansetron; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Randomized Controlled Trials as Topic; Reproducibility of Results; Tramadol; Transcutaneous Electric Nerve Stimulation; Treatment Outcome

1998
Pain management in dental practice: tramadol vs. codeine combinations.
    Journal of the American Dental Association (1939), 1999, Volume: 130, Issue:7

    Topics: Acetaminophen; Adrenergic Uptake Inhibitors; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Codeine; Drug Combinations; Drug Evaluation; Facial Pain; Humans; Pain, Postoperative; Tramadol

1999
Rational use of analgesic combinations.
    Dental clinics of North America, 2002, Volume: 46, Issue:4

    Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Anxiety; Clinical Protocols; Codeine; Contraindications; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dental Care; Dose-Response Relationship, Drug; Drug Combinations; Humans; Hydrocodone; Isoenzymes; Membrane Proteins; Oxycodone; Pain; Prostaglandin-Endoperoxide Synthases; Stress, Physiological; Tramadol

2002
Are one or two dangerous? Opioid exposure in toddlers.
    The Journal of emergency medicine, 2005, Volume: 29, Issue:1

    Topics: Analgesics, Opioid; Child, Preschool; Codeine; Dose-Response Relationship, Drug; Drug Overdose; Emergency Medicine; Fentanyl; Humans; Infant; Methadone; Pediatrics; Poisoning; Tramadol

2005
[What are the cardiovascular complications of the analgesics and glucocorticoids?].
    Presse medicale (Paris, France : 1983), 2006, Volume: 35, Issue:9 Spec No

    Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Buprenorphine; Cardiovascular Diseases; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Glucocorticoids; Humans; Morphine; Nalbuphine; Nefopam; Risk Assessment; Risk Factors; Time Factors; Tramadol

2006
Genetic factors in pain and its treatment.
    Current opinion in anaesthesiology, 2007, Volume: 20, Issue:5

    Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Catechol O-Methyltransferase; Codeine; Cytochrome P-450 Enzyme System; Ethnicity; Forecasting; Gene Frequency; Genetic Predisposition to Disease; Humans; Pain; Pain Management; Pain Threshold; Pharmacogenetics; Receptor, Melanocortin, Type 1; Receptors, Opioid, mu; Tramadol

2007
[Weak opioids. Pain and Locoregional Anesthesia Committee and the Standards Committee of the French Society of Anesthesia and Intensive Care].
    Annales francaises d'anesthesie et de reanimation, 2009, Volume: 28, Issue:2

    Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; Codeine; Dextropropoxyphene; Drug Therapy, Combination; Evidence-Based Medicine; Gastrointestinal Diseases; Humans; Infusions, Intravenous; Injections, Intravenous; Meta-Analysis as Topic; Narcotics; Pain, Postoperative; Randomized Controlled Trials as Topic; Respiratory Insufficiency; Tramadol

2009
The second step of the analgesic ladder and oral tramadol in the treatment of mild to moderate cancer pain: a systematic review.
    Palliative medicine, 2011, Volume: 25, Issue:5

    Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Codeine; Humans; Neoplasms; Pain; Pain Measurement; Practice Guidelines as Topic; Severity of Illness Index; Tramadol

2011
Influence of Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) polymorphisms on pain sensitivity and clinical response to weak opioid analgesics.
    Drug metabolism and pharmacokinetics, 2014, Volume: 29, Issue:1

    Topics: Analgesics, Opioid; Codeine; Cytochrome P-450 CYP2D6; Humans; Pain; Pain Threshold; Polymorphism, Genetic; Tramadol

2014
Tramadol can selectively manage moderate pain in children following European advice limiting codeine use.
    Acta paediatrica (Oslo, Norway : 1992), 2014, Volume: 103, Issue:11

    Topics: Analgesics, Opioid; Child; Codeine; Europe; Humans; Pain; Pain Measurement; Severity of Illness Index; Tramadol

2014
"Weak" opioid analgesics. Codeine, dihydrocodeine and tramadol: no less risky than morphine.
    Prescrire international, 2016, Volume: 25, Issue:168

    Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Codeine; Dose-Response Relationship, Drug; Humans; Morphine; Respiration; Tramadol

2016
Opioids for cancer pain - an overview of Cochrane reviews.
    The Cochrane database of systematic reviews, 2017, 07-06, Volume: 7

    Topics: Acetaminophen; Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Buprenorphine; Cancer Pain; Codeine; Fentanyl; Humans; Hydromorphone; Methadone; Oxycodone; Phenols; Review Literature as Topic; Tapentadol; Tramadol

2017
[Opioids for Cancer Pain and its Use under Particular Conditions: A Narrative Review].
    Acta medica portuguesa, 2019, May-31, Volume: 32, Issue:5

    Topics: Administration, Oral; Analgesics, Opioid; Buprenorphine; Cancer Pain; Codeine; Deglutition Disorders; Fentanyl; Humans; Hydromorphone; Liver Failure; Morphine; Oxycodone; Renal Dialysis; Renal Insufficiency; Tapentadol; Tramadol

2019
Comparative risk-benefit profiles of weak opioids in the treatment of osteoarthritis: a network meta-analysis of randomized controlled trials.
    Postgraduate medicine, 2022, Volume: 134, Issue:8

    Topics: Analgesics, Opioid; Codeine; Dextropropoxyphene; Humans; Network Meta-Analysis; Osteoarthritis; Pain; Randomized Controlled Trials as Topic; Tramadol

2022
The Role of Pharmacogenomics in Opioid Prescribing.
    Current treatment options in oncology, 2022, Volume: 23, Issue:10

    Topics: Analgesics, Opioid; Codeine; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2D6; Humans; Methadone; Oxycodone; Pharmacogenetics; Practice Patterns, Physicians'; Tramadol

2022

Trials

28 trial(s) available for tramadol and codeine

ArticleYear
A comparison of the effects of codeine and tramadol on laryngeal reactivity.
    European journal of anaesthesiology, 1992, Volume: 9, Issue:2

    Topics: Adult; Codeine; Double-Blind Method; Female; Humans; Larynx; Male; Reference Values; Reflex; Tramadol

1992
Lack of analgesic effect of 50 and 100 mg oral tramadol after orthopaedic surgery: a randomized, double-blind, placebo and standard active drug comparison.
    Pain, 1995, Volume: 62, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Bone and Bones; Bupivacaine; Codeine; Double-Blind Method; Hip Prosthesis; Humans; Middle Aged; Pain Measurement; Pain, Postoperative; Tramadol

1995
Analgesic effects of dihydrocodeine and tramadol when administered either in the morning or evening.
    Chronobiology international, 1995, Volume: 12, Issue:1

    Topics: Acoustic Stimulation; Adult; Circadian Rhythm; Codeine; Female; Humans; Male; Pain; Randomized Controlled Trials as Topic; Stimulation, Chemical; Tramadol

1995
Opioid and opioid-like drug effects on whole-gut transit measured by scintigraphy.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1996, Volume: 37, Issue:5

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; Colon; Cross-Over Studies; Double-Blind Method; Drug Combinations; Gastric Emptying; Gastrointestinal Transit; Humans; Indium Radioisotopes; Intestine, Small; Male; Pentetic Acid; Radionuclide Imaging; Stomach; Technetium Tc 99m Sulfur Colloid; Tramadol

1996
Analgesia after day case laparoscopic sterilisation. A comparison of tramadol with paracetamol/dextropropoxyphene and paracetamol/codeine combinations.
    Anaesthesia, 1997, Volume: 52, Issue:7

    Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Analgesia; Analgesics, Opioid; Codeine; Dextropropoxyphene; Double-Blind Method; Drug Combinations; Female; Humans; Laparoscopy; Pain, Postoperative; Sterilization, Tubal; Tramadol

1997
Tramadol hydrochloride: analgesic efficacy compared with codeine, aspirin with codeine, and placebo after dental extraction.
    Journal of clinical pharmacology, 1998, Volume: 38, Issue:6

    Topics: Adolescent; Adult; Aged; Analgesia; Analgesics, Opioid; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Codeine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pain, Postoperative; Tooth Extraction; Tramadol

1998
A comparison of the effects of intravenous tramadol, codeine, and morphine on gastric emptying in human volunteers.
    Anesthesia and analgesia, 1998, Volume: 87, Issue:2

    Topics: Acetaminophen; Adult; Analgesics, Opioid; Codeine; Cross-Over Studies; Double-Blind Method; Female; Gastric Emptying; Humans; Infusions, Intravenous; Male; Morphine; Tramadol

1998
Tramadol suppositories are less suitable for post-operative pain relief than rectal acetaminophen/codeine.
    European journal of anaesthesiology, 1999, Volume: 16, Issue:7

    Topics: Acetaminophen; Administration, Rectal; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; Confidence Intervals; Drug Combinations; Female; Humans; Incidence; Male; Middle Aged; Movement; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Rest; Suppositories; Tramadol

1999
Analgesia after intracranial surgery: a double-blind, prospective comparison of codeine and tramadol.
    British journal of anaesthesia, 1999, Volume: 83, Issue:2

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Codeine; Craniotomy; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Nausea; Pain Measurement; Pain, Postoperative; Prospective Studies; Tramadol; Vomiting

1999
Behavioural measurement of postoperative pain after oral surgery.
    The British journal of oral & maxillofacial surgery, 2000, Volume: 38, Issue:2

    Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Alveolectomy; Analgesia; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Behavior; Citrates; Codeine; Drug Combinations; Female; Humans; Male; Middle Aged; Molar, Third; Oral Surgical Procedures; Pain Measurement; Pain, Postoperative; Reproducibility of Results; Self-Assessment; Sex Factors; Tooth Extraction; Tramadol

2000
Treatment of severe pain from osteoarthritis with slow-release tramadol or dihydrocodeine in combination with NSAID's: a randomised study comparing analgesia, antinociception and gastrointestinal effects.
    Pain, 2001, Volume: 91, Issue:1-2

    Topics: Adult; Aged; Analgesia; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Codeine; Delayed-Action Preparations; Digestive System; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gastrointestinal Transit; Humans; Male; Middle Aged; Nociceptors; Osteoarthritis; Pain; Pain Measurement; Pain Threshold; Palliative Care; Severity of Illness Index; Sleep; Tramadol

2001
Tramadol/acetaminophen combination tablets and codeine/acetaminophen combination capsules for the management of chronic pain: a comparative trial.
    Clinical therapeutics, 2001, Volume: 23, Issue:9

    Topics: Acetaminophen; Administration, Oral; Adult; Aged; Analgesics; Analgesics, Opioid; Codeine; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pain; Pain Measurement; Tramadol; Treatment Outcome

2001
The pupillary effects of intravenous morphine, codeine, and tramadol in volunteers.
    Anesthesia and analgesia, 2004, Volume: 99, Issue:1

    Topics: Adult; Analgesics, Opioid; Codeine; Cross-Over Studies; Double-Blind Method; Female; Humans; Injections, Intravenous; Male; Morphine; Pupil; Tramadol

2004
Onset of analgesia and analgesic efficacy of tramadol/acetaminophen and codeine/acetaminophen/ibuprofen in acute postoperative pain: a single-center, single-dose, randomized, active-controlled, parallel-group study in a dental surgery pain model.
    Clinical therapeutics, 2004, Volume: 26, Issue:7

    Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Opioid; Codeine; Drug Combinations; Female; Humans; Ibuprofen; Male; Pain, Postoperative; Time Factors; Tooth Extraction; Tramadol

2004
Comparative trial of tramadol/paracetamol and codeine/paracetamol combination tablets on the vigilance of healthy volunteers.
    Fundamental & clinical pharmacology, 2005, Volume: 19, Issue:6

    Topics: Acetaminophen; Attention; Codeine; Double-Blind Method; Drug Combinations; Humans; Reaction Time; Reference Values; Tablets; Tramadol

2005
Tramadol/acetaminophen tablets in the treatment of postsurgical orthopedic pain.
    American journal of orthopedics (Belle Mead, N.J.), 2005, Volume: 34, Issue:12

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Codeine; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Orthopedics; Pain Measurement; Pain, Postoperative; Tramadol; Treatment Outcome

2005
Preincisional paravertebral block reduces the prevalence of chronic pain after breast surgery.
    Anesthesia and analgesia, 2006, Volume: 103, Issue:3

    Topics: Acetaminophen; Analgesia, Epidural; Breast Neoplasms; Bupivacaine; Codeine; Follow-Up Studies; Humans; Ibuprofen; Nerve Block; Pain; Pain, Postoperative; Placebos; Single-Blind Method; Tramadol; Treatment Outcome

2006
Incidence of weak opioids adverse events in the management of cancer pain: a double-blind comparative trial.
    Journal of palliative medicine, 2007, Volume: 10, Issue:1

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Codeine; Double-Blind Method; Female; Humans; Hydrocodone; Incidence; Male; Middle Aged; Neoplasms; Pain; Pain Measurement; Palliative Care; Quality of Life; Tramadol; Treatment Outcome

2007
Comparison of the analgesic efficacy and respiratory effects of morphine, tramadol and codeine after craniotomy.
    Anaesthesia, 2007, Volume: 62, Issue:6

    Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Carbon Dioxide; Codeine; Conscious Sedation; Craniotomy; Female; Humans; Injections, Intramuscular; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Partial Pressure; Postoperative Nausea and Vomiting; Respiration; Tramadol

2007
[Assessment of quality in day-case hand surgery].
    Annales francaises d'anesthesie et de reanimation, 2009, Volume: 28, Issue:9

    Topics: Acetaminophen; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Local; Carpal Tunnel Syndrome; Codeine; Cohort Studies; Dextropropoxyphene; Drug Therapy, Combination; Female; Hand; Humans; Ketoprofen; Male; Middle Aged; Pain, Postoperative; Patient Satisfaction; Periosteum; Quality Assurance, Health Care; Time Factors; Tramadol

2009
Magnesium and headache after aneurysmal subarachnoid haemorrhage.
    Journal of neurology, neurosurgery, and psychiatry, 2010, Volume: 81, Issue:5

    Topics: Analgesics; Analgesics, Opioid; Codeine; Female; Headache; Humans; Injections, Intravenous; Logistic Models; Magnesium Sulfate; Male; Middle Aged; Pain Measurement; Pirinitramide; Stroke; Subarachnoid Hemorrhage; Tramadol

2010
The impact of tramadol and dihydrocodeine treatment on quality of life of patients with cancer pain.
    International journal of clinical practice, 2010, Volume: 64, Issue:12

    Topics: Aged; Analgesics, Opioid; Analysis of Variance; Codeine; Cross-Over Studies; Delayed-Action Preparations; Female; Humans; Karnofsky Performance Status; Male; Neoplasms; Nociceptive Pain; Pain Measurement; Patient Satisfaction; Tramadol; Treatment Outcome

2010
Analgesia with paracetamol/tramadol vs. paracetamol/codeine in one day-surgery: a randomized open study.
    European review for medical and pharmacological sciences, 2011, Volume: 15, Issue:2

    Topics: Acetaminophen; Adult; Aged; Ambulatory Surgical Procedures; Analgesia; Codeine; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pain, Postoperative; Tramadol

2011
Abuse liability and reinforcing efficacy of oral tramadol in humans.
    Drug and alcohol dependence, 2013, Apr-01, Volume: 129, Issue:1-2

    Topics: Administration, Oral; Adolescent; Adult; Analgesics, Opioid; Carbon Dioxide; Codeine; Cohort Studies; Double-Blind Method; Female; Flicker Fusion; Hemodynamics; Humans; Male; Middle Aged; Oxycodone; Oxygen; Psychomotor Performance; Pupil; Receptors, Opioid, mu; Reinforcement, Psychology; Self Administration; Substance-Related Disorders; Tramadol; Young Adult

2013
Comparison of the postoperative analgesic effects of paracetamol-codeine phosphate and naproxen sodium-codeine phosphate for lumbar disk surgery.
    The Kaohsiung journal of medical sciences, 2015, Volume: 31, Issue:9

    Topics: Acetaminophen; Adult; Analgesics, Opioid; Codeine; Female; Humans; Lumbar Vertebrae; Male; Middle Aged; Naproxen; Pain, Postoperative; Postoperative Period; Tramadol

2015
Drug-gene and drug-drug interactions associated with tramadol and codeine therapy in the INGENIOUS trial.
    Pharmacogenomics, 2019, Volume: 20, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Codeine; Cytochrome P-450 CYP2D6; Drug Interactions; Female; Humans; Male; Middle Aged; Pharmacogenetics; Tramadol; Young Adult

2019
Is tramadol associated to bleeding peptic ulcer? A nationwide case-control study in hospitalized Swedish patients.
    PloS one, 2019, Volume: 14, Issue:4

    Topics: Aged; Aged, 80 and over; Case-Control Studies; Codeine; Female; Humans; Male; Middle Aged; Peptic Ulcer; Peptic Ulcer Hemorrhage; Registries; Sweden; Tramadol

2019
Implementing a pragmatic clinical trial to tailor opioids for acute pain on behalf of the IGNITE ADOPT PGx investigators.
    Clinical and translational science, 2022, Volume: 15, Issue:10

    Topics: Acute Pain; Analgesics, Opioid; Codeine; Cytochrome P-450 CYP2D6; Humans; Hydrocodone; Pain, Postoperative; Practice Patterns, Physicians'; Prospective Studies; Tramadol

2022

Other Studies

125 other study(ies) available for tramadol and codeine

ArticleYear
Opioids as Substrates and Inhibitors of the Genetically Highly Variable Organic Cation Transporter OCT1.
    Journal of medicinal chemistry, 2019, 11-14, Volume: 62, Issue:21

    Topics: Analgesics, Opioid; HEK293 Cells; Humans; Inhibitory Concentration 50; Models, Molecular; Organic Cation Transporter 1; Permeability; Protein Conformation

2019
Relationship between the antitussic and analgesic activity of substances.
    Acta physiologica Hungarica, 1991, Volume: 77, Issue:2

    Topics: Analgesia; Analgesics; Animals; Antitussive Agents; Cats; Codeine; Cough; Female; Male; Naloxone; Pentazocine; Tilidine; Tramadol

1991
[The effect of flupirtine, various analgesics and muscle relaxants on skeletal muscle tone in the conscious rat].
    Arzneimittel-Forschung, 1990, Volume: 40, Issue:8

    Topics: Aminopyridines; Analgesics; Animals; Anti-Anxiety Agents; Baclofen; Benzodiazepines; Benzodiazepinones; Codeine; Dantrolene; Diazepam; Female; Mephenesin; Morphine; Motor Activity; Muscle Relaxants, Central; Muscle Tonus; Rats; Rats, Inbred Strains; Tramadol

1990
Comparative physical dependence studies in rats with flupirtine and opiate receptor stimulating analgesics.
    Postgraduate medical journal, 1987, Volume: 63 Suppl 3

    Topics: Aminopyridines; Analgesics; Animals; Body Weight; Buprenorphine; Codeine; Female; Rats; Rats, Inbred Strains; Receptors, Opioid; Substance-Related Disorders; Tramadol

1987
Receptor binding, analgesic and antitussive potency of tramadol and other selected opioids.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:7

    Topics: Animals; Antitussive Agents; Brain Chemistry; Codeine; Cyclohexanols; Dose-Response Relationship, Drug; Male; Membranes; Naloxone; Narcotics; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid; Tramadol

1988
Intrathecal injection of codeine, buprenorphine, tilidine, tramadol and nefopam depresses the tail-flick response in rats.
    European journal of pharmacology, 1986, Jan-14, Volume: 120, Issue:1

    Topics: Analgesics; Animals; Buprenorphine; Codeine; Depression, Chemical; Female; Injections, Spinal; Male; Naloxone; Nefopam; Rats; Reaction Time; Tilidine; Tramadol

1986
[Therapy of chronic pancreatitis].
    Deutsche medizinische Wochenschrift (1946), 1996, May-24, Volume: 121, Issue:21

    Topics: Analgesics, Opioid; Bile Ducts; Buprenorphine; Chronic Disease; Codeine; Humans; Morphine; Pain; Pancreatitis; Pentazocine; Sphincter of Oddi; Tramadol

1996
[Changes in the pattern of opioid analgesic consumption in Spain].
    Medicina clinica, 1997, Sep-13, Volume: 109, Issue:8

    Topics: Administration, Oral; Administration, Rectal; Analgesics, Opioid; Buprenorphine; Codeine; Databases as Topic; Dextropropoxyphene; Drug Prescriptions; Humans; Injections, Intravenous; Linear Models; Meperidine; Methadone; Morphine; Pentazocine; Spain; Tilidine; Tramadol

1997
[Pain therapy].
    Presse medicale (Paris, France : 1983), 1998, Dec-12, Volume: 27, Issue:39

    Topics: Adult; Age Factors; Analgesics; Analgesics, Opioid; Child; Codeine; Humans; Methadone; Neurosurgery; Pain Management; Pain, Intractable; Pain, Postoperative; Tramadol

1998
Tramadol: new preparation. Capsules: central analgesic; step 2 on the WHO scale.
    Prescrire international, 1998, Volume: 7, Issue:33

    Topics: Acetaminophen; Aged; Analgesics, Opioid; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Double-Blind Method; France; Humans; Meta-Analysis as Topic; Morphine; Pain; Patient Compliance; Substance-Related Disorders; Tramadol; Treatment Outcome; World Health Organization

1998
[Opioids. Pharmacology, clinic, prospectives for an extensive use].
    Recenti progressi in medicina, 2000, Volume: 91, Issue:12

    Topics: Analgesics, Opioid; Codeine; Drug Tolerance; Fentanyl; Humans; Hydromorphone; Methadone; Morphine; Oxycodone; Receptors, Opioid; Tramadol

2000
[Paliative treatment: Treatment of chronic cancer pain (ii): the use of opiates].
    Atencion primaria, 2002, May-15, Volume: 29, Issue:8

    Topics: Administration, Cutaneous; Administration, Oral; Age Factors; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Disease; Codeine; Fentanyl; Humans; Morphine; Narcotics; Neoplasms; Pain; Palliative Care; Time Factors; Tramadol

2002
Paracetamol + tramadol: new preparation. No advance.
    Prescrire international, 2003, Volume: 12, Issue:68

    Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Codeine; Drug Therapy, Combination; France; Humans; Ibuprofen; Pain; Tramadol; Treatment Outcome

2003
Weak opiate analgesics: modest practical merits.
    Prescrire international, 2004, Volume: 13, Issue:69

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Drug Combinations; Humans; Ibuprofen; Meta-Analysis as Topic; Pain; Pain Measurement; Tramadol

2004
Drug interactions with the potential to prevent prodrug activation as a common source of irrational prescribing in hospital inpatients.
    Clinical pharmacology and therapeutics, 2004, Volume: 76, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Biotransformation; Codeine; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6 Inhibitors; Databases, Nucleic Acid; Drug Interactions; Drug Prescriptions; Enzyme Inhibitors; Female; Humans; Losartan; Male; Medication Errors; Medication Systems, Hospital; Middle Aged; Prodrugs; Sex Factors; Tramadol

2004
Opioid purchases and expenditure in nine western European countries: 'are we killing off morphine?'.
    Palliative medicine, 2005, Volume: 19, Issue:3

    Topics: Codeine; Europe; Fentanyl; Health Expenditures; Humans; Morphine; Narcotics; Pharmacies; Tramadol

2005
Tramadol oral solution: new drug. Poorly evaluated and potentially dangerous in children.
    Prescrire international, 2005, Volume: 14, Issue:77

    Topics: Analgesics, Opioid; Child; Child, Preschool; Clinical Trials as Topic; Codeine; Drug Approval; France; Humans; Pain, Postoperative; Tramadol; Treatment Outcome

2005
Derivatives of tramadol for increased duration of effect.
    Bioorganic & medicinal chemistry letters, 2006, Volume: 16, Issue:3

    Topics: Analgesics, Opioid; Animals; Binding Sites; Codeine; Models, Chemical; Morphine; Pain; Rats; Time Factors; Tramadol

2006
Comparative metabolic capabilities and inhibitory profiles of CYP2D6.1, CYP2D6.10, and CYP2D6.17.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:8

    Topics: Atomoxetine Hydrochloride; Cocaine; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Debrisoquin; Dextromethorphan; Enzyme Inhibitors; Ethanolamines; Fluoxetine; Humans; Hydroxylation; Imipramine; Kinetics; Microsomes; Molecular Structure; Nortriptyline; Polymorphism, Single Nucleotide; Propylamines; Quinidine; Recombinant Proteins; Thioridazine; Tramadol

2007
Codeine and tramadol analgesic efficacy and respiratory effects are influenced by CYP2D6 genotype.
    Anaesthesia, 2007, Volume: 62, Issue:12

    Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Codeine; Cytochrome P-450 CYP2D6; Drug Administration Schedule; Genotype; Humans; Pain, Postoperative; Tramadol

2007
Unexceptional seizure potential of tramadol or its enantiomers or metabolites in mice.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 325, Issue:2

    Topics: Analgesics, Opioid; Animals; Codeine; Cytochrome P-450 CYP2D6 Inhibitors; Drug Interactions; Hot Temperature; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Narcotic Antagonists; Oxycodone; Pain; Quinidine; Reserpine; Seizures; Stereoisomerism; Tramadol

2008
The risk of motor vehicle accidents involving drivers with prescriptions for codeine or tramadol.
    Clinical pharmacology and therapeutics, 2009, Volume: 85, Issue:6

    Topics: Accidents, Traffic; Adolescent; Adult; Aged; Analgesics, Opioid; Automobile Driving; Codeine; Drug Utilization; Female; Humans; Male; Middle Aged; Polypharmacy; Prescription Drugs; Tramadol; Young Adult

2009
Cooperative opioid and serotonergic mechanisms generate superior antidepressant-like effects in a mice model of depression.
    The international journal of neuropsychopharmacology, 2009, Volume: 12, Issue:8

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Behavior, Animal; Codeine; Depression; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Duloxetine Hydrochloride; Enzyme Inhibitors; Hindlimb Suspension; Male; Mice; Motor Activity; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes; Tramadol

2009
Reporting rate of adverse drug reactions to the French pharmacovigilance system with three step 2 analgesic drugs: dextropropoxyphene, tramadol and codeine (in combination with paracetamol).
    British journal of clinical pharmacology, 2009, Volume: 68, Issue:3

    Topics: Acetaminophen; Adverse Drug Reaction Reporting Systems; Analgesics, Opioid; Codeine; Databases, Factual; Dextropropoxyphene; Drug Therapy, Combination; France; Humans; Tramadol

2009
Codeine-induced generalized dermatitis and tolerance to other opioids.
    Allergy, 2009, Volume: 64, Issue:11

    Topics: Administration, Oral; Adult; Analgesics, Opioid; Codeine; Dermatitis; Drug Hypersensitivity; Female; Fentanyl; Humans; Skin Tests; Tramadol

2009
Utilization characteristics and treatment persistence in patients prescribed low-dose buprenorphine patches in primary care in the United Kingdom: a retrospective cohort study.
    Clinical therapeutics, 2009, Volume: 31, Issue:8

    Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Buprenorphine; Chronic Disease; Codeine; Cohort Studies; Databases, Factual; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Male; Medication Adherence; Middle Aged; Pain; Primary Health Care; Proportional Hazards Models; Retrospective Studies; Time Factors; Tramadol; United Kingdom; Young Adult

2009
Simultaneous quantitation of morphine, 6-acetylmorphine, codeine, 6-acetylcodeine and tramadol in hair using mixed-mode solid-phase extraction and gas chromatography-mass spectrometry.
    Analytical and bioanalytical chemistry, 2010, Volume: 396, Issue:8

    Topics: Calibration; Codeine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Limit of Detection; Morphine; Morphine Derivatives; Solid Phase Extraction; Tramadol

2010
[Codeine and cutaneous drug reactions: Absence of cross-allergy with tramadol and fentanyl].
    Annales de dermatologie et de venereologie, 2010, Volume: 137, Issue:5

    Topics: Adult; Bromhexine; Codeine; Cross Reactions; Drug Eruptions; Edema; Expectorants; Female; Fentanyl; Humans; Patch Tests; Pruritus; Tramadol

2010
Comparison of the effects of tramadol, codeine, and ketoprofen alone or in combination on postoperative pain and on concentrations of blood glucose, serum cortisol, and serum interleukin-6 in dogs undergoing maxillectomy or mandibulectomy.
    American journal of veterinary research, 2010, Volume: 71, Issue:9

    Topics: Analgesics, Opioid; Animals; Blood Glucose; Codeine; Dog Diseases; Dogs; Drug Therapy, Combination; Female; Hydrocortisone; Ketoprofen; Male; Mandible; Mandibular Diseases; Mandibular Neoplasms; Maxilla; Maxillary Diseases; Maxillary Neoplasms; Pain, Postoperative; Tramadol

2010
Analgesic effects and assays of controlled-release tramadol and o-desmethyltramadol in cancer patients with pain.
    Current pharmaceutical biotechnology, 2011, Feb-01, Volume: 12, Issue:2

    Topics: Aged; Aged, 80 and over; Analgesia; Analgesics, Opioid; Codeine; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Middle Aged; Neoplasms; Pain; Pain Measurement; Tramadol

2011
The comparative safety of opioids for nonmalignant pain in older adults.
    Archives of internal medicine, 2010, Dec-13, Volume: 170, Issue:22

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Codeine; Cohort Studies; Cyclooxygenase 2 Inhibitors; Dextropropoxyphene; Female; Fractures, Bone; Gastrointestinal Hemorrhage; Hospitalization; Humans; Hydrocodone; Incidence; Male; Medicare; Odds Ratio; Oxycodone; Pain; Pain Measurement; Tramadol; United States

2010
Codeine v. morphine.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2011, Jan-11, Volume: 183, Issue:1

    Topics: Analgesics, Opioid; Codeine; Humans; Tramadol

2011
Post-craniotomy pain in a paediatric population.
    Anaesthesia and intensive care, 2011, Volume: 39, Issue:1

    Topics: Acetaminophen; Adolescent; Age Factors; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; Codeine; Craniotomy; Female; Humans; Ibuprofen; Infant; Male; Morphine; Oxycodone; Pain Measurement; Pain, Postoperative; Pediatrics; Time Factors; Tramadol

2011
Analgesic prescribing practices can be improved by low-cost point-of-care decision support.
    Journal of pain and symptom management, 2011, Volume: 42, Issue:4

    Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Codeine; Decision Support Techniques; Drug Prescriptions; Female; Humans; Hydrocodone; Infant; Infant, Newborn; Male; Pain; Pain Management; Pain Measurement; Practice Patterns, Physicians'; Tramadol

2011
Attitude and knowledge of physicians about cancer pain management: young doctors of South Korea in their early career.
    Japanese journal of clinical oncology, 2011, Volume: 41, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Attitude of Health Personnel; Benzodiazepines; Codeine; Drug Prescriptions; Drug Therapy, Combination; Drug Tolerance; Female; Fentanyl; Health Knowledge, Attitudes, Practice; Humans; Male; Medicine; Meperidine; Neoplasms; Pain; Pain Measurement; Physicians; Practice Patterns, Physicians'; Republic of Korea; Research Design; Self Concept; Substance-Related Disorders; Surveys and Questionnaires; Tramadol

2011
Canadian guideline for safe and effective use of opioids for chronic noncancer pain: clinical summary for family physicians. Part 1: general population.
    Canadian family physician Medecin de famille canadien, 2011, Volume: 57, Issue:11

    Topics: Analgesics, Opioid; Benzodiazepines; Canada; Chronic Pain; Codeine; Humans; Hydromorphone; Mass Screening; Opioid-Related Disorders; Oxycodone; Patient Education as Topic; Sleep Apnea Syndromes; Tramadol

2011
[Study of codeine-paracetamol combination treatment compared with tramadol-paracetamol in the control of moderate-to-severe low back pain].
    Minerva medica, 2012, Volume: 103, Issue:3

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; Drug Therapy, Combination; Female; Humans; Low Back Pain; Male; Middle Aged; Osteoarthritis, Spine; Pain Management; Tramadol

2012
Comparison of fatal poisonings by prescription opioids.
    Forensic science international, 2012, Oct-10, Volume: 222, Issue:1-3

    Topics: Accidents; Adolescent; Adult; Analgesics, Opioid; Buprenorphine; Central Nervous System Depressants; Codeine; Dextropropoxyphene; Drug Overdose; Ethanol; Fentanyl; Finland; Forensic Toxicology; Humans; Hypnotics and Sedatives; Methadone; Morphine; Opioid-Related Disorders; Oxycodone; Poisoning; Prescription Drug Misuse; Suicide; Tramadol; Young Adult

2012
Tramadol and hypoglycaemia: comparison with other step 2 analgesic drugs.
    British journal of clinical pharmacology, 2013, Volume: 75, Issue:4

    Topics: Aged; Analgesics; Blood Glucose; Codeine; Databases, Factual; Dextropropoxyphene; Female; France; Humans; Hypoglycemia; Male; Risk Factors; Tramadol

2013
Semiological evaluation of pain according to its origin: a prospective, observational, and national study of current French medical practice.
    Current medical research and opinion, 2013, Volume: 29, Issue:6

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; Drug Combinations; Female; France; Humans; Male; Middle Aged; Pain; Pain Measurement; Prospective Studies; Surveys and Questionnaires; Tramadol; Treatment Outcome

2013
The advantages and limitations of the analgesics available for control of postoperative pain after a dental procedure.
    SAAD digest, 2013, Volume: 29

    Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Codeine; Cyclooxygenase 2 Inhibitors; Dental Care; Diclofenac; Diflunisal; Drug Combinations; Humans; Ibuprofen; Narcotics; Oral Surgical Procedures; Pain, Postoperative; Tramadol

2013
A preliminary evaluation of the effects of opioids on innate and adaptive human in vitro immune function.
    BMJ supportive & palliative care, 2014, Volume: 4, Issue:4

    Topics: Adaptive Immunity; Adult; Analgesics, Opioid; Buprenorphine; Codeine; Fentanyl; Humans; Immunity, Innate; Interleukin-2; Interleukin-6; Leukocytes, Mononuclear; Methadone; Monocytes; Morphine; Neutrophils; Oxycodone; Phagocytosis; Respiratory Burst; Tramadol

2014
Hair analysis to demonstrate administration of amitriptyline, temazepam, tramadol and dihydrocodeine to a child in a case of kidnap and false imprisonment.
    Journal of forensic and legal medicine, 2014, Volume: 23

    Topics: Amitriptyline; Analgesics, Opioid; Antidepressive Agents; Child; Chromatography, Liquid; Codeine; Crime; Forensic Toxicology; Hair; Humans; Hypnotics and Sedatives; Tandem Mass Spectrometry; Temazepam; Tramadol

2014
CYP2D6-inhibiting drugs and the increased risk of fall-related injuries due to newly initiated opioid treatment--a Swedish, register-based case-crossover study.
    Basic & clinical pharmacology & toxicology, 2015, Volume: 116, Issue:2

    Topics: Accidental Falls; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Case-Control Studies; Codeine; Cross-Over Studies; Cytochrome P-450 CYP2D6 Inhibitors; Drug Interactions; Humans; Male; Middle Aged; Oxycodone; Registries; Risk; Sweden; Tramadol; Young Adult

2015
Pharmacoepidemiological assessment of drug interactions with vitamin K antagonists.
    Pharmacoepidemiology and drug safety, 2014, Volume: 23, Issue:11

    Topics: Age Factors; Aged; Aged, 80 and over; Analgesics, Opioid; Anticoagulants; Cardiovascular Diseases; Codeine; Denmark; Drug Interactions; Female; Humans; Insurance Claim Review; International Normalized Ratio; Male; Pharmacoepidemiology; Phenprocoumon; Prescription Drugs; Sex Factors; Tramadol; Vitamin K; Warfarin

2014
Rescheduling of hydrocodone combination products.
    The Medical letter on drugs and therapeutics, 2014, Oct-13, Volume: 56, Issue:1453

    Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Codeine; Controlled Substances; Drug and Narcotic Control; Drug Therapy, Combination; Humans; Hydrocodone; Ibuprofen; Pain; Tramadol

2014
A description of clinical characteristics and treatment patterns observed within prescribed opioid users in Germany and the UK.
    Pain management, 2014, Volume: 4, Issue:4

    Topics: Analgesics, Opioid; Codeine; Cohort Studies; Drug Prescriptions; Female; Germany; Humans; Male; Pain Management; Prescription Drugs; Tramadol; Treatment Outcome; United Kingdom

2014
Tramadol for noncancer pain and the risk of hyponatremia.
    The American journal of medicine, 2015, Volume: 128, Issue:4

    Topics: Adult; Aged; Analgesics, Opioid; Codeine; Female; Hospitalization; Humans; Hyponatremia; Incidence; Male; Medical Records; Middle Aged; Odds Ratio; Pain; Propensity Score; Proportional Hazards Models; Retrospective Studies; Risk; Sodium; Tramadol; United Kingdom

2015
Tramadol use and the risk of hospitalization for hypoglycemia in patients with noncancer pain.
    JAMA internal medicine, 2015, Volume: 175, Issue:2

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Case-Control Studies; Codeine; Cohort Studies; Female; Hospitalization; Humans; Hypoglycemia; Male; Middle Aged; Pain; Tramadol

2015
Accuracy of using Diagnosis Procedure Combination administrative claims data for estimating the amount of opioid consumption among cancer patients in Japan.
    Japanese journal of clinical oncology, 2015, Volume: 45, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Codeine; Drug Prescriptions; Female; Fentanyl; Humans; Insurance Claim Review; Japan; Male; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain; Tramadol

2015
Evaluation of the use of clinical decision support and online resources for pharmacogenomics education.
    Pharmacogenomics, 2015, Volume: 16, Issue:14

    Topics: Analgesics, Opioid; Codeine; Cytochrome P-450 CYP2D6; Decision Support Systems, Clinical; Drug Combinations; Educational Measurement; Electronic Mail; Humans; Information Dissemination; Internet; Pharmacogenetics; Surveys and Questionnaires; Tramadol

2015
Australian GP management of osteoarthritis following the release of the RACGP guideline for the non-surgical management of hip and knee osteoarthritis.
    BMC research notes, 2015, Oct-05, Volume: 8

    Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Australia; Codeine; Disease Management; Drug Combinations; Female; General Practitioners; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteoarthritis, Knee; Practice Guidelines as Topic; Practice Patterns, Physicians'; Risk; Surveys and Questionnaires; Tramadol

2015
Trends in analgesic exposures reported to Texas Poison Centers following increased regulation of hydrocodone.
    Clinical toxicology (Philadelphia, Pa.), 2016, Volume: 54, Issue:5

    Topics: Analgesics; Analgesics, Opioid; Codeine; Drug and Narcotic Control; Government Regulation; Heroin; Humans; Hydrocodone; Opioid-Related Disorders; Oxycodone; Poison Control Centers; Prescription Drug Misuse; Texas; Tramadol

2016
Satisfaction, Adherence and Health-Related Quality of Life with Transdermal Buprenorphine Compared with Oral Opioid Medications in the Usual Care of Osteoarthritis Pain.
    The patient, 2016, Volume: 9, Issue:4

    Topics: Acetaminophen; Administration, Cutaneous; Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Buprenorphine; Codeine; Drug Combinations; Female; Humans; Male; Medication Adherence; Middle Aged; Osteoarthritis; Pain Measurement; Patient Satisfaction; Prospective Studies; Quality of Life; Severity of Illness Index; Surveys and Questionnaires; Tramadol; United Kingdom

2016
Can routine information from electronic patient records predict a future diagnosis of alcohol use disorder?
    Scandinavian journal of primary health care, 2016, Volume: 34, Issue:3

    Topics: Adult; Aged; Alcoholism; Analgesics, Opioid; Benzodiazepines; Codeine; Early Diagnosis; Electronic Health Records; Erythrocyte Indices; Ethylmorphine; Female; gamma-Glutamyltransferase; General Practice; Humans; Male; Middle Aged; Norway; Proportional Hazards Models; Risk Factors; Sick Leave; Tramadol; Young Adult

2016
Fast determination of codeine, orphenadrine, promethazine, scopolamine, tramadol, and paracetamol in pharmaceutical formulations by capillary electrophoresis.
    Journal of separation science, 2017, Volume: 40, Issue:8

    Topics: Acetaminophen; Codeine; Drug Compounding; Electrophoresis, Capillary; Orphenadrine; Promethazine; Scopolamine; Tramadol

2017
Opioids Inhibit Angiogenesis in a Chorioallantoic Membrane Model.
    Pain physician, 2017, Volume: 20, Issue:2S

    Topics: Analgesics, Opioid; Animals; Chickens; Chorioallantoic Membrane; Codeine; Female; Humans; Neovascularization, Pathologic; Prospective Studies; Tramadol

2017
FDA warns against use of codeine and tramadol in children and breastfeeding women.
    The Medical letter on drugs and therapeutics, 2017, 05-22, Volume: 59, Issue:1521

    Topics: Adolescent; Age Factors; Analgesics, Opioid; Breast Feeding; Child; Codeine; Female; Humans; Male; Respiratory Insufficiency; Risk Assessment; Risk Factors; Tramadol; United States; United States Food and Drug Administration

2017
The Effect of Opioid Prescribing Guidelines on Prescriptions by Emergency Physicians in Ohio.
    Annals of emergency medicine, 2017, Volume: 70, Issue:6

    Topics: Adult; Analgesics, Opioid; Codeine; Emergency Service, Hospital; Female; Guideline Adherence; Humans; Hydrocodone; Hydromorphone; Male; Middle Aged; Ohio; Oxycodone; Practice Guidelines as Topic; Practice Patterns, Physicians'; Tramadol

2017
Tramadol: keep calm and carry on.
    Paediatric anaesthesia, 2017, Volume: 27, Issue:8

    Topics: Analgesics, Opioid; Codeine; Cytochrome P-450 CYP2D6; Humans; Respiratory Insufficiency; Tramadol; United States; United States Food and Drug Administration

2017
Codeine and Tramadol Contraindicated for Pediatric Use.
    The American journal of nursing, 2017, Volume: 117, Issue:8

    Topics: Analgesics, Opioid; Breast Feeding; Child; Codeine; Contraindications, Drug; Humans; Pain; Tramadol

2017
Risks of Codeine and Tramadol in Children.
    JAMA, 2017, 10-17, Volume: 318, Issue:15

    Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; Codeine; Cough; Humans; Infant; Prescription Drug Misuse; Sleep Wake Disorders; Tramadol; United States; United States Food and Drug Administration

2017
Analgesic Consumption Following Outpatient Carpal Tunnel Release.
    The Journal of hand surgery, 2018, Volume: 43, Issue:2

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Analgesics; Carpal Tunnel Syndrome; Codeine; Drug Combinations; Female; Humans; Male; Middle Aged; Pain, Postoperative; Prospective Studies; Tablets; Tramadol; Young Adult

2018
Evaluation of opioid prescribing after rescheduling of hydrocodone-containing products.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2017, Dec-15, Volume: 74, Issue:24

    Topics: Adolescent; Adult; Analgesics, Opioid; Child; Child, Preschool; Codeine; Controlled Substances; Drug and Narcotic Control; Drug Prescriptions; Female; Humans; Hydrocodone; Inpatients; Male; Middle Aged; Outpatients; Oxycodone; Practice Patterns, Physicians'; Retrospective Studies; Tramadol; Young Adult

2017
CYP2D6 drug-gene and drug-drug-gene interactions among patients prescribed pharmacogenetically actionable opioids.
    Applied nursing research : ANR, 2017, Volume: 38

    Topics: Adult; Aged; Analgesics, Opioid; Codeine; Cytochrome P-450 CYP2D6; Female; Humans; Male; Middle Aged; Pharmacogenetics; Tramadol; Young Adult

2017
Pain Treatment Practices of Community-Dwelling Black Older Adults.
    Pain management nursing : official journal of the American Society of Pain Management Nurses, 2018, Volume: 19, Issue:1

    Topics: Aged; Anthropology, Cultural; Black or African American; Codeine; Exercise Therapy; Faith Healing; Female; Healthcare Disparities; Housing for the Elderly; Humans; Hydrocodone; Ibuprofen; Male; Medicine, Traditional; Middle Aged; Naproxen; Pain; Pain Management; Pain Measurement; Psychometrics; Qualitative Research; Surveys and Questionnaires; Tramadol

2018
Internet pseudoscience: Testing opioid containing formulations with tampering potential.
    Journal of pharmaceutical and biomedical analysis, 2018, May-10, Volume: 153

    Topics: Acetaminophen; Analgesics, Opioid; Chemistry, Pharmaceutical; Chromatography, Liquid; Codeine; Dextromethorphan; Internet; Tablets; Tandem Mass Spectrometry; Tramadol

2018
Use of analgesics in France, following dextropropoxyphene withdrawal.
    BMC health services research, 2018, 04-02, Volume: 18, Issue:1

    Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Codeine; Dextropropoxyphene; Drug Combinations; Drug Prescriptions; France; Humans; Pain; Pain Management; Safety-Based Drug Withdrawals; Tramadol

2018
The dilemma of repeat weak opioid prescriptions - experiences from swedish GPs.
    Scandinavian journal of primary health care, 2018, Volume: 36, Issue:2

    Topics: Adaptation, Psychological; Adult; Analgesics, Opioid; Attitude of Health Personnel; Chronic Pain; Codeine; Drug Prescriptions; Emotions; Ethics, Medical; Female; Focus Groups; General Practice; General Practitioners; Humans; Male; Middle Aged; Physician-Patient Relations; Practice Patterns, Physicians'; Qualitative Research; Stress, Psychological; Sweden; Tramadol

2018
Clinical application of pharmacogenetics in pain management.
    Personalized medicine, 2018, Volume: 15, Issue:2

    Topics: Analgesics, Opioid; Codeine; Cytochrome P-450 CYP2D6; Genomics; Genotype; Humans; Hydrocodone; Oxycodone; Pain Management; Pharmacogenetics; Polymorphism, Genetic; Precision Medicine; Tramadol

2018
Anticholinergic and sedative drug burden in community-dwelling older people: a national database study.
    BMJ open, 2018, 07-06, Volume: 8, Issue:7

    Topics: Acetaminophen; Aged; Aged, 80 and over; Alprazolam; Analgesics; Analgesics, Opioid; Azabicyclo Compounds; Cholinergic Antagonists; Codeine; Cross-Sectional Studies; Databases, Factual; Drug Combinations; Female; Humans; Hypnotics and Sedatives; Independent Living; Ireland; Male; Odds Ratio; Pharmacoepidemiology; Piperazines; Pregabalin; Sex Factors; Sleep Aids, Pharmaceutical; Tramadol; Zolpidem

2018
Demographic Characteristics and Functional Performance of the Kidneys and Hearts of Patients with Acute Tramadol Toxicity.
    Drug research, 2019, Volume: 69, Issue:4

    Topics: Adolescent; Adult; Analgesics, Opioid; Codeine; Cross-Sectional Studies; Demography; Drug Overdose; Female; Heart; Humans; Iran; Kidney; Male; Physical Functional Performance; Receptors, Opioid, mu; Seizures; Single-Blind Method; Tramadol; Young Adult

2019
Prescription opioid analgesic use in France: Trends and impact on morbidity-mortality.
    European journal of pain (London, England), 2019, Volume: 23, Issue:1

    Topics: Adult; Aged; Analgesics, Opioid; Chronic Pain; Codeine; Databases, Factual; Dextropropoxyphene; Female; Fentanyl; France; Humans; Male; Middle Aged; Mortality; Opioid-Related Disorders; Opium; Oxycodone; Prevalence; Proportional Hazards Models; Tramadol

2019
Vomiting and constipation associated with tramadol and codeine: a comparative study in VigiBase®.
    European journal of clinical pharmacology, 2018, Volume: 74, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Codeine; Constipation; Databases, Factual; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Tramadol; Vomiting; Young Adult

2018
Which opioids in case of mast cell activation disorders?
    The journal of allergy and clinical immunology. In practice, 2019, Volume: 7, Issue:4

    Topics: Analgesics, Opioid; Codeine; Databases, Factual; Histamine Release; Humans; Hydromorphone; Mast Cells; Mastocytosis; Pharmacovigilance; Tramadol

2019
Profiles of visuospatial memory dysfunction in opioid-exposed and dependent populations.
    Psychological medicine, 2019, Volume: 49, Issue:7

    Topics: Adult; Agnosia; Analgesics, Opioid; Chronic Pain; Codeine; Female; Heroin Dependence; Humans; Male; Memory Disorders; Mental Recall; Methadone; Neuropsychological Tests; Risk Factors; Tramadol; United Kingdom

2019
The Use of Codeine and Tramadol in the Pediatric Population-What is the Verdict Now?
    Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners, 2019, Volume: 33, Issue:1

    Topics: Analgesics, Opioid; Child; Child, Preschool; Codeine; Contraindications, Drug; Cytochrome P-450 CYP2D6; Guideline Adherence; Humans; Pain Management; Respiratory Insufficiency; Tramadol; United States; United States Food and Drug Administration

2019
Think twice before prescribing certain drugs to children.
    The British journal of oral & maxillofacial surgery, 2019, Volume: 57, Issue:1

    Topics: Analgesics, Opioid; Child; Codeine; Humans; Hydrocodone; Morphine; Tramadol

2019
Oral Opioid Use during Vaginal Delivery Hospitalizations.
    American journal of perinatology, 2020, Volume: 37, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Analgesics, Opioid; Codeine; Databases, Factual; Delivery, Obstetric; Drug Utilization; Female; Hospitalization; Humans; Insurance, Health; Opioid-Related Disorders; Pain; Pregnancy; Tramadol; Young Adult

2020
Identification of opioids in surface and wastewaters by LC/QTOF-MS using retrospective data analysis.
    The Science of the total environment, 2019, May-10, Volume: 664

    Topics: Analgesics, Opioid; Chromatography, Liquid; Codeine; Data Analysis; Environmental Monitoring; Fentanyl; Heroin; Hydrocodone; Hydromorphone; Minnesota; Morphine; Morphine Derivatives; Oxycodone; Retrospective Studies; Substance Abuse Detection; Tandem Mass Spectrometry; Tramadol; Wastewater; Water Pollutants, Chemical

2019
Association of Tramadol With All-Cause Mortality Among Patients With Osteoarthritis.
    JAMA, 2019, 03-12, Volume: 321, Issue:10

    Topics: Age Factors; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Body Mass Index; Codeine; Cohort Studies; Comorbidity; Confounding Factors, Epidemiologic; Female; Humans; Male; Middle Aged; Mortality; Osteoarthritis; Propensity Score; Tramadol

2019
Tramadol and the risk of seizure: nested case-control study of US patients with employer-sponsored health benefits.
    BMJ open, 2019, 03-13, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Analgesics, Opioid; Case-Control Studies; Codeine; Female; Health Benefit Plans, Employee; Humans; Insurance, Health; Male; Middle Aged; Retrospective Studies; Seizures; Tramadol; United States; United States Food and Drug Administration; Young Adult

2019
Tramadol- and codeine-induced severe hyponatremia: A Swedish population-based case-control study.
    European journal of internal medicine, 2019, Volume: 69

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Case-Control Studies; Codeine; Female; Hospitalization; Humans; Hyponatremia; Male; Middle Aged; Retrospective Studies; Severity of Illness Index; Sweden; Tramadol; Young Adult

2019
A national study on the use of opioid analgesics in dentistry.
    Brazilian oral research, 2019, Aug-15, Volume: 33

    Topics: Acetaminophen; Analgesics, Opioid; Brazil; Codeine; Cross-Sectional Studies; Dental Care; Drug Prescriptions; Drug Utilization; Humans; Pharmacies; Practice Patterns, Dentists'; Reference Values; Socioeconomic Factors; Statistics, Nonparametric; Tramadol

2019
Prescription opioid dispensing in Australian children and adolescents: a national population-based study.
    The Lancet. Child & adolescent health, 2019, Volume: 3, Issue:12

    Topics: Adolescent; Analgesics, Opioid; Australia; Child; Child, Preschool; Codeine; Drug Prescriptions; Drug Utilization; Female; Humans; Infant; Infant, Newborn; Male; Oxycodone; Prevalence; Tramadol

2019
Association of tramadol with risk of myocardial infarction among patients with osteoarthritis.
    Osteoarthritis and cartilage, 2020, Volume: 28, Issue:2

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Codeine; Diclofenac; Female; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Naproxen; Osteoarthritis; Propensity Score; Proportional Hazards Models; Risk Factors; Tramadol

2020
Opioid prescribing practices in a pediatric burn tertiary care facility: Is it time to change?
    Burns : journal of the International Society for Burn Injuries, 2020, Volume: 46, Issue:1

    Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Adolescent; Ambulatory Care; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Burn Units; Burns; Child; Child, Preschool; Codeine; Drug Combinations; Female; Fentanyl; Hospitalization; Humans; Hydrocodone; Hydromorphone; Infant; Length of Stay; Male; Morphine; Pain Management; Patient Discharge; Practice Patterns, Physicians'; Retrospective Studies; Tertiary Care Centers; Tramadol

2020
Alleviation of Pain After Femur and Tibia Shaft Fractures Using Nothing Stronger Than Codeine and Tramadol.
    Journal of orthopaedic trauma, 2020, Volume: 34, Issue:2

    Topics: Adult; Codeine; Femur; Humans; Pain; Retrospective Studies; Tibia; Tibial Fractures; Tramadol

2020
Postmortem Brain-Blood Ratios of Codeine, Fentanyl, Oxycodone and Tramadol.
    Journal of analytical toxicology, 2021, Feb-06, Volume: 45, Issue:1

    Topics: Analgesics, Opioid; Autopsy; Codeine; Drug Overdose; Fentanyl; Forensic Toxicology; Humans; Oxycodone; Substance Abuse Detection; Tramadol

2021
Recreational drug use among Nigerian university students: Prevalence, correlates and frequency of use.
    PloS one, 2020, Volume: 15, Issue:5

    Topics: Adolescent; Adult; Amphetamine-Related Disorders; Codeine; Cross-Sectional Studies; Female; Humans; Illicit Drugs; Male; Marijuana Use; Nigeria; Prevalence; Risk Factors; Students; Substance-Related Disorders; Surveys and Questionnaires; Tramadol; Universities; Young Adult

2020
CYP2D6 Basic Genotyping of Patients with Chronic Pain Receiving Tramadol or Codeine. A Study in a Greek Cohort.
    Pain medicine (Malden, Mass.), 2020, 11-01, Volume: 21, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Pain; Codeine; Cohort Studies; Cytochrome P-450 CYP2D6; Female; Genotype; Greece; Humans; Male; Middle Aged; Prospective Studies; Tramadol; Young Adult

2020
Continued Prescribing of Periprocedural Codeine and Tramadol to Children after a Black Box Warning.
    The Journal of surgical research, 2020, Volume: 256

    Topics: Administrative Claims, Healthcare; Adolescent; Ambulatory Surgical Procedures; Child; Child, Preschool; Codeine; Drug Labeling; Drug Prescriptions; Female; Humans; Inappropriate Prescribing; Infant; Male; Pain, Postoperative; Perioperative Care; Practice Patterns, Physicians'; Retrospective Studies; Tramadol; Wisconsin

2020
Trends in hydrocodone combination product exposures reported to California Poison Control System (CPCS) following DEA rescheduling.
    Clinical toxicology (Philadelphia, Pa.), 2021, Volume: 59, Issue:4

    Topics: California; Codeine; Drug and Narcotic Control; Drug Overdose; Drug Prescriptions; Fentanyl; Heroin; Humans; Hydrocodone; Interrupted Time Series Analysis; Morphine; Oxycodone; Poison Control Centers; Tramadol

2021
Tramadol non-medical use in Four European countries: A comparative analysis.
    Drug and alcohol dependence, 2020, 12-01, Volume: 217

    Topics: Adult; Analgesics, Opioid; Codeine; Cross-Sectional Studies; Europe; Female; Germany; Humans; Italy; Male; Middle Aged; Morphine; Opioid-Related Disorders; Oxycodone; Prescription Drug Misuse; Prescription Drugs; Spain; Tramadol; United Kingdom; Young Adult

2020
Comparison of Opioids Prescribed for Patients at Risk for Opioid Misuse Before and After Publication of the Centers for Disease Control and Prevention's Opioid Prescribing Guidelines.
    JAMA network open, 2020, 12-01, Volume: 3, Issue:12

    Topics: Adult; Analgesics, Opioid; Centers for Disease Control and Prevention, U.S.; Codeine; Cross-Sectional Studies; Drug Prescriptions; Female; Guideline Adherence; Guidelines as Topic; Humans; Hydrocodone; Male; Middle Aged; Opioid-Related Disorders; Oxycodone; Practice Patterns, Physicians'; Tramadol; United States

2020
Provider specialty and odds of a new codeine, hydrocodone, oxycodone and tramadol prescription before and after the CDC opioid prescribing guideline publication.
    Preventive medicine, 2021, Volume: 146

    Topics: Analgesics, Opioid; Centers for Disease Control and Prevention, U.S.; Codeine; Drug Prescriptions; Humans; Hydrocodone; Oxycodone; Practice Patterns, Physicians'; Tramadol; United States

2021
Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between CYP2D6 and opioids (codeine, tramadol and oxycodone).
    European journal of human genetics : EJHG, 2022, Volume: 30, Issue:10

    Topics: Adult; Analgesics, Opioid; Child; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P450 Family 2; Drug Interactions; Humans; Oxycodone; Pharmacogenetics; Tramadol

2022
Pharmaceutical opioid poisonings in Victoria, Australia: Rates and characteristics of a decade of emergency department presentations among nine pharmaceutical opioids.
    Addiction (Abingdon, England), 2022, Volume: 117, Issue:3

    Topics: Adolescent; Adult; Analgesics, Opioid; Child; Codeine; Drug Overdose; Emergency Service, Hospital; Female; Fentanyl; Humans; Morphine; Oxycodone; Pharmaceutical Preparations; Tramadol; Victoria; Young Adult

2022
Postmortem Analysis of Opioids and Metabolites in Skeletal Tissue.
    Journal of analytical toxicology, 2022, Aug-13, Volume: 46, Issue:7

    Topics: Analgesics, Opioid; Chromatography, Liquid; Codeine; Fentanyl; Morphine; Tramadol

2022
Patient-Centered Decision-making for Postoperative Narcotic-Free Endocrine Surgery: A Randomized Clinical Trial.
    JAMA surgery, 2021, 11-01, Volume: 156, Issue:11

    Topics: Acetaminophen; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; Female; Humans; Hydrocodone; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Parathyroidectomy; Patient Preference; Patient-Centered Care; Quality of Life; Thyroidectomy; Tramadol

2021
Tramadol versus codeine and the short-term risk of cardiovascular events in patients with non-cancer pain: A population-based cohort study.
    British journal of clinical pharmacology, 2022, Volume: 88, Issue:4

    Topics: Analgesics, Opioid; Angina, Unstable; Brain Ischemia; Codeine; Cohort Studies; Humans; Ischemic Stroke; Myocardial Infarction; Proportional Hazards Models; Retrospective Studies; Stroke; Tramadol

2022
Association of Tramadol vs Codeine Prescription Dispensation With Mortality and Other Adverse Clinical Outcomes.
    JAMA, 2021, 10-19, Volume: 326, Issue:15

    Topics: Accidental Falls; Ambulatory Care; Analgesics, Opioid; Cardiovascular Diseases; Cause of Death; Codeine; Databases, Factual; Delirium; Drug Prescriptions; Female; Fractures, Bone; Humans; Incidence; Male; Middle Aged; Opioid-Related Disorders; Propensity Score; Proportional Hazards Models; Retrospective Studies; Sleep Wake Disorders; Tramadol

2021
Tramadol, Codeine, and Risk of Adverse Outcomes.
    JAMA, 2021, 10-19, Volume: 326, Issue:15

    Topics: Analgesics, Opioid; Codeine; Tramadol

2021
Opioid Analgesic Prescription in French Children: A National Population-Based Study.
    International journal of environmental research and public health, 2021, 12-17, Volume: 18, Issue:24

    Topics: Analgesics, Opioid; Child; Codeine; Humans; Morphine; Practice Patterns, Physicians'; Prescriptions; Tramadol

2021
Association of Tramadol vs Codeine Prescriptions With Mortality and Other Adverse Clinical Outcomes-Reply.
    JAMA, 2022, 02-01, Volume: 327, Issue:5

    Topics: Analgesics, Opioid; Codeine; Prescriptions; Tramadol

2022
Association of Tramadol vs Codeine Prescription Dispensation With Mortality and Other Adverse Outcomes.
    JAMA, 2022, 02-01, Volume: 327, Issue:5

    Topics: Analgesics, Opioid; Codeine; Prescriptions; Tramadol

2022
Association of Tramadol vs Codeine Prescription Dispensation With Mortality and Other Adverse Outcomes.
    JAMA, 2022, 02-01, Volume: 327, Issue:5

    Topics: Analgesics, Opioid; Codeine; Prescriptions; Tramadol

2022
Association between tramadol use and risk of pneumonia in the middle-aged and elderly populations: a propensity-score matched cohort study.
    European journal of pain (London, England), 2022, Volume: 26, Issue:6

    Topics: Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Codeine; Cohort Studies; Diclofenac; Etoricoxib; Humans; Middle Aged; Naproxen; Pneumonia; Tramadol

2022
Association of tramadol with all-cause mortality, cardiovascular diseases, venous thromboembolism, and hip fractures among patients with osteoarthritis: a population-based study.
    Arthritis research & therapy, 2022, 04-11, Volume: 24, Issue:1

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Codeine; Cohort Studies; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Hip Fractures; Humans; Male; Osteoarthritis; Tramadol; Venous Thromboembolism

2022
Rapid Extraction and Qualitative Screening of 30 Drugs in Oral Fluid at Concentrations Recommended for the Investigation of DUID Cases.
    Journal of analytical toxicology, 2022, Oct-14, Volume: 46, Issue:8

    Topics: 2-Propanol; 3,4-Methylenedioxyamphetamine; Alprazolam; Amphetamines; Buprenorphine; Carisoprodol; Clonazepam; Cocaine; Codeine; Dronabinol; Fentanyl; Hexanes; Hydrocodone; Hydromorphone; Lorazepam; Meprobamate; Methadone; Methamphetamine; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Nordazepam; Oxazepam; Oxycodone; Oxymorphone; Pharmaceutical Preparations; Phencyclidine; Tandem Mass Spectrometry; Temazepam; Tramadol; Zolpidem

2022
Identification of a novel opioid,
    Clinical toxicology (Philadelphia, Pa.), 2022, Volume: 60, Issue:9

    Topics: Adult; Alprazolam; Analgesics, Opioid; Benzimidazoles; Cocaine; Codeine; Drug Overdose; Fentanyl; Heroin; Humans; Illicit Drugs; Levamisole; Middle Aged; Naloxone; Narcotic Antagonists; Opiate Overdose; Phenacetin; Prospective Studies; Tramadol

2022
Impact of Hydrocodone Rescheduling on Dental Prescribing of Opioids.
    JDR clinical and translational research, 2023, Volume: 8, Issue:4

    Topics: Analgesics, Opioid; Codeine; Cross-Sectional Studies; Drug Prescriptions; Hydrocodone; Oxycodone; Practice Patterns, Dentists'; Tramadol; United States

2023
Opioid dispensing after Cesarean delivery in British Columbia: a historical cohort analysis from 2004 to 2019.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2022, Volume: 69, Issue:8

    Topics: Aftercare; Analgesics, Opioid; British Columbia; Codeine; Cohort Studies; Humans; Hydromorphone; Patient Discharge; Practice Patterns, Physicians'; Tramadol

2022
Hip Fracture Risk After Treatment with Tramadol or Codeine: An Observational Study.
    Drug safety, 2022, Volume: 45, Issue:7

    Topics: Aged; Analgesics, Opioid; Codeine; Hip Fractures; Humans; Pain; Quality of Life; Tramadol

2022
Tramadol and Codeine Stacking/Boosting Dose Exposure Induced Neurotoxic Behaviors, Oxidative Stress, Mitochondrial Dysfunction, and Neurotoxic Genes in Adolescent Mice.
    Neurotoxicity research, 2022, Volume: 40, Issue:5

    Topics: Analgesics, Opioid; Animals; Codeine; Mice; Mitochondria; Nootropic Agents; Oxidative Stress; Pharmaceutical Preparations; Tramadol

2022
Characteristics of Prescription Opioid Analgesics in Pregnancy and Risk of Neonatal Opioid Withdrawal Syndrome in Newborns.
    JAMA network open, 2022, 08-01, Volume: 5, Issue:8

    Topics: Adult; Analgesics, Opioid; Codeine; Cohort Studies; Female; Humans; Hydrocodone; Hydromorphone; Infant, Newborn; Infant, Newborn, Diseases; Methadone; Morphine; Neonatal Abstinence Syndrome; Oxycodone; Pain; Pregnancy; Prescriptions; Substance Withdrawal Syndrome; Tramadol; United States

2022
Simultaneous Quantification of Opioids in Blood and Urine by Gas Chromatography-Mass Spectrometer with Modified Dispersive Solid-Phase Extraction Technique.
    Molecules (Basel, Switzerland), 2022, Oct-10, Volume: 27, Issue:19

    Topics: Acetonitriles; Analgesics, Opioid; Codeine; Dextromethorphan; Gas Chromatography-Mass Spectrometry; Humans; Morphine; Morphine Derivatives; Nalbuphine; Solid Phase Extraction; Solvents; Substance Abuse Detection; Tramadol

2022
Impact of the 2017 FDA Drug Safety Communication on Codeine and Tramadol Dispensing to Children.
    Pediatrics, 2022, 11-01, Volume: 150, Issue:5

    Topics: Analgesics, Opioid; Child; Codeine; Communication; Humans; Tramadol

2022
An assessment of drug and substance abuse prevalence: a cross-sectional study among undergraduates in selected southwestern universities in Nigeria.
    The Journal of international medical research, 2022, Volume: 50, Issue:10

    Topics: Codeine; Cross-Sectional Studies; Female; Humans; Male; Nigeria; Prevalence; Students; Substance-Related Disorders; Surveys and Questionnaires; Tramadol; Universities

2022
The opioid epidemic: A worldwide exploratory study using the WHO pharmacovigilance database.
    Addiction (Abingdon, England), 2023, Volume: 118, Issue:4

    Topics: Analgesics, Opioid; Bayes Theorem; Codeine; Fentanyl; Humans; Morphine; Opioid Epidemic; Opioid-Related Disorders; Oxycodone; Pharmacovigilance; Tramadol; World Health Organization

2023
Application of oxidized multi-walled carbon nanotubes and zeolite nanoparticles for simultaneous preconcentration of codeine and tramadol in saliva prior to HPLC determination.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2023, May-01, Volume: 1222

    Topics: Chromatography, High Pressure Liquid; Codeine; Humans; Nanotubes, Carbon; Saliva; Solid Phase Extraction; Tramadol; Zeolites

2023
Trends in adverse drug reactions related to oral weak opioid analgesics in therapeutic use in adults: A 10-year French vigilances retrospective study.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:6

    Topics: Acute Disease; Adult; Adverse Drug Reaction Reporting Systems; Analgesics, Opioid; Codeine; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Pancreatitis; Pharmacovigilance; Retrospective Studies; Tramadol; Young Adult

2023
The opioid tramadol blocks the cardiac sodium channel Nav1.5 in HEK293 cells.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2023, 08-02, Volume: 25, Issue:9

    Topics: Analgesics, Opioid; Animals; Codeine; Fentanyl; HEK293 Cells; Humans; Myocytes, Cardiac; Rabbits; Sodium Channel Blockers; Tramadol

2023
Use of opioids among pregnant women 1997-2016: A Danish drug utilization study.
    European journal of obstetrics, gynecology, and reproductive biology, 2023, Volume: 289

    Topics: Analgesics, Opioid; Codeine; Denmark; Drug Utilization; Female; Humans; Pregnancy; Pregnant Women; Tramadol

2023
Exploring Perceptions About Paracetamol, Tramadol, and Codeine on Twitter Using Machine Learning: Quantitative and Qualitative Observational Study.
    Journal of medical Internet research, 2023, 11-14, Volume: 25

    Topics: Acetaminophen; Codeine; Humans; Machine Learning; Pain; Social Media; Tramadol

2023