tram-34 and candesartan

tram-34 has been researched along with candesartan* in 1 studies

Other Studies

1 other study(ies) available for tram-34 and candesartan

Article	Year
Inhibitory effects of candesartan on KCa3.1 potassium channel expression and cell culture and proliferation in peripheral blood CD4 Clinical and experimental hypertension (New York, N.Y. : 1993), 2018, Volume: 40, Issue:4 Increasing evidence confirms that potassium channels are essential for lymphocyte activation, suggesting an involvement in the development of hypertension. Moreover, chronic inflammation is regarded as a direct or indirect manifestation of hypertension, highlighting the theoretical mechanisms. In this study, we investigated changes in KCa3.1 potassium channel expression in the blood of hypertensive and healthy Kazakh people in north-west China.. Flow cytometry technology was used for T-lymphocyte subtype analysis. Changes in the messenger RNA and protein expression of the KCa3.1 potassium channel in CD4. Expression of KCa3.1 was significantly higher in the hypertensive patients than in the controls (p < 0.05). Compared with the healthy group, Kazakh hypertensive patients had a reduced proportion of CD4. Increase in functional KCa3.1 channels expressed in CD4 Topics: Adult; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Case-Control Studies; CD4-Positive T-Lymphocytes; Cell Culture Techniques; Cell Proliferation; China; Female; Humans; Hypertension; Intermediate-Conductance Calcium-Activated Potassium Channels; Kazakhstan; Kv1.3 Potassium Channel; Male; Middle Aged; Protein Biosynthesis; Pyrazoles; RNA, Messenger; Tetrazoles; Transcription, Genetic	2018

Article

Year

Inhibitory effects of candesartan on KCa3.1 potassium channel expression and cell culture and proliferation in peripheral blood CD4

Clinical and experimental hypertension (New York, N.Y. : 1993), 2018, Volume: 40, Issue:4

Increasing evidence confirms that potassium channels are essential for lymphocyte activation, suggesting an involvement in the development of hypertension. Moreover, chronic inflammation is regarded as a direct or indirect manifestation of hypertension, highlighting the theoretical mechanisms. In this study, we investigated changes in KCa3.1 potassium channel expression in the blood of hypertensive and healthy Kazakh people in north-west China.. Flow cytometry technology was used for T-lymphocyte subtype analysis. Changes in the messenger RNA and protein expression of the KCa3.1 potassium channel in CD4. Expression of KCa3.1 was significantly higher in the hypertensive patients than in the controls (p < 0.05). Compared with the healthy group, Kazakh hypertensive patients had a reduced proportion of CD4. Increase in functional KCa3.1 channels expressed in CD4

Topics: Adult; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Case-Control Studies; CD4-Positive T-Lymphocytes; Cell Culture Techniques; Cell Proliferation; China; Female; Humans; Hypertension; Intermediate-Conductance Calcium-Activated Potassium Channels; Kazakhstan; Kv1.3 Potassium Channel; Male; Middle Aged; Protein Biosynthesis; Pyrazoles; RNA, Messenger; Tetrazoles; Transcription, Genetic

2018