Page last updated: 2024-08-21

toyocamycin and nsc 65346

toyocamycin has been researched along with nsc 65346 in 30 studies

Research

Studies (30)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (33.33)	18.7374
1990's	6 (20.00)	18.2507
2000's	8 (26.67)	29.6817
2010's	6 (20.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bernier-Rodriguez, M; Drach, JC; Kern, ER; Krawczyk, SH; Nassiri, MR; Townsend, LB; Wotring, LL	1
Daunert, S; Drach, JC; Gupta, PK; Nassiri, MR; Townsend, LB; Wotring, LL	1
Balzarini, J; De Clercq, E; Hansske, F; Madej, D; Robins, MJ	1
Balzarini, J; Bergstrom, DE; Brattesani, AJ; De Clercq, E; Ogawa, MK; Reddy, PA; Schweickert, MJ	1
Drach, JC; Renau, TE; Townsend, LB; Wotring, LL	1
Browne, CE; DaRe, JM; Erion, MD; Kopcho, JJ; Schanzer, JM; Ugarkar, BG; Wiesner, JB	1
Debnath, B; Jha, T; Srikanth, K	1
González, MP; Moldes del Carmen Terán, M	1
Caballero, J; Fernández, M; González-Nilo, FD	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Feng, Y; Hooper, JN; Mellick, G; Murtaza, M; Quinn, RJ; Wang, D; Wood, S	1
Barbeau, O; Burke, R; Cheeseman, MD; Collins, I; Dobson, S; Jeganathan, F; Jones, AM; Jones, K; Kadi, N; Rowlands, M; van Montfort, RL; Westwood, IM; Workman, P	1
Bayle, ED; Fish, PV; Li, F; Schapira, M; Spurr, SS; Tempel, W; Vedadi, M; Yu, W	1
Coleman, LA; Drach, JC; Saxena, NK; Townsend, LB	1
Hargrave, PA; Kahn, N; Palczewski, K	1
Coleman, LA; Drach, JC; Gupta, PK; Nassiri, MR; Townsend, LB; Wotring, LL	1
Cohen, MB; Glazer, RI	2
Bojarska, E; Czochralska, B; Pawlicki, K	1
Cheng, HW; Rice, A; Verham, R; Wang, AL; Wang, CC	1
Gupta, RS; Mehta, KD	1
Glazer, RI; Saffer, JD	1
Drach, JC; Kern, ER; Krawczyk, SH; Kucera, LS; Nassiri, MR; Ptak, RG; Townsend, LB; Wotring, LL	1
Breitenbach, JM; Drach, JC; Kennedy, C; Ptak, RG; Renau, TE; Townsend, LB	1
Kato, A; Maeba, I; Nishimura, N	1
An, H; Ding, Y; Girardet, JL; Hong, Z	1
Bandarian, V; McCarty, RM	1
Kang, J; Lee, CH; Lee, DK	1
Bandarian, V; Nelp, MT; Song, Y; Wysocki, VH	1
Bai, J; Ding, H; Dong, X; Hu, C; Tang, J; Xiao, Q	1

Other Studies

30 other study(ies) available for toyocamycin and nsc 65346

Article	Year
Arabinofuranosylpyrrolo[2,3-d]pyrimidines as potential agents for human cytomegalovirus infections. Journal of medicinal chemistry, 1990, Volume: 33, Issue:12 Topics: Animals; Antiviral Agents; Arabinonucleosides; Cell Division; Chemical Phenomena; Chemistry; Cytomegalovirus; Cytomegalovirus Infections; Humans; Leukemia L1210; Mice; Molecular Structure; Pyrimidine Nucleosides; Simplexvirus; Structure-Activity Relationship; Toyocamycin; Tumor Cells, Cultured	1990
Synthesis, cytotoxicity, and antiviral activity of some acyclic analogues of the pyrrolo[2,3-d]pyrimidine nucleoside antibiotics tubercidin, toyocamycin, and sangivamycin. Journal of medicinal chemistry, 1989, Volume: 32, Issue:2 Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antiviral Agents; Cell Division; Humans; Mice; Pyrimidine Nucleosides; Structure-Activity Relationship; Toyocamycin; Tubercidin	1989
Nucleic acid related compounds. 51. Synthesis and biological properties of sugar-modified analogues of the nucleoside antibiotics tubercidin, toyocamycin, sangivamycin, and formycin. Journal of medicinal chemistry, 1987, Volume: 30, Issue:3 Topics: Animals; Antibiotics, Antineoplastic; Antiviral Agents; Formycins; Leukemia L1210; Mice; Microbial Sensitivity Tests; Pyrimidine Nucleosides; Ribonucleosides; Structure-Activity Relationship; Toyocamycin; Tubercidin	1987
Antiviral activity of C-5 substituted tubercidin analogues. Journal of medicinal chemistry, 1984, Volume: 27, Issue:3 Topics: Animals; Antibiotics, Antineoplastic; Antiviral Agents; Chlorocebus aethiops; DNA Viruses; HeLa Cells; Humans; Mice; Pyrimidine Nucleosides; Rabbits; Ribonucleosides; RNA Viruses; Toyocamycin; Tubercidin	1984
Synthesis of non-nucleoside analogs of toyocamycin, sangivamycin, and ++thiosangivamycin: influence of various 7-substituents on antiviral activity. Journal of medicinal chemistry, 1996, Feb-16, Volume: 39, Issue:4 Topics: Antiviral Agents; Cell Survival; Cells, Cultured; Cytomegalovirus; Fibroblasts; Herpesvirus 1, Human; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Microbial Sensitivity Tests; Molecular Structure; Pyrimidine Nucleosides; Pyrimidines; Skin; Structure-Activity Relationship; Thionucleosides; Toyocamycin; Viral Plaque Assay	1996
Adenosine kinase inhibitors. 1. Synthesis, enzyme inhibition, and antiseizure activity of 5-iodotubercidin analogues. Journal of medicinal chemistry, 2000, Jul-27, Volume: 43, Issue:15 Topics: Adenosine Kinase; Animals; Anticonvulsants; Electroshock; Enzyme Inhibitors; Humans; Male; Rats; Recombinant Proteins; Seizures; Structure-Activity Relationship; Tubercidin	2000
QSAR study on adenosine kinase inhibition of pyrrolo[2,3-d]pyrimidine nucleoside analogues using the hansch approach. Bioorganic & medicinal chemistry letters, 2002, Mar-25, Volume: 12, Issue:6 Topics: Adenosine Kinase; Biodegradation, Environmental; Hydrophobic and Hydrophilic Interactions; Ligands; Pyrimidines; Pyrroles; Quantitative Structure-Activity Relationship	2002
A TOPS-MODE approach to predict adenosine kinase inhibition. Bioorganic & medicinal chemistry letters, 2004, Jun-21, Volume: 14, Issue:12 Topics: Adenosine Kinase; Enzyme Inhibitors; Models, Molecular; Predictive Value of Tests; Quantitative Structure-Activity Relationship	2004
A CoMSIA study on the adenosine kinase inhibition of pyrrolo[2,3-d]pyrimidine nucleoside analogues. Bioorganic & medicinal chemistry, 2008, May-01, Volume: 16, Issue:9 Topics: Adenosine Kinase; Computer Simulation; Databases, Factual; Enzyme Inhibitors; Models, Chemical; Models, Molecular; Molecular Structure; Nucleosides; Pyrimidines; Pyrroles; Quantitative Structure-Activity Relationship; Reproducibility of Results; Stereoisomerism	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
A Grand Challenge: Unbiased Phenotypic Function of Metabolites from Jaspis splendens against Parkinson's Disease. Journal of natural products, 2016, Feb-26, Volume: 79, Issue:2 Topics: Animals; Depsipeptides; Drug Screening Assays, Antitumor; Humans; Indole Alkaloids; Molecular Structure; Parkinson Disease; Porifera	2016
Exploiting Protein Conformational Change to Optimize Adenosine-Derived Inhibitors of HSP70. Journal of medicinal chemistry, 2016, 05-26, Volume: 59, Issue:10 Topics: Adenosine; Crystallography, X-Ray; Dose-Response Relationship, Drug; HSP70 Heat-Shock Proteins; Humans; Models, Molecular; Molecular Conformation; Structure-Activity Relationship	2016
New small molecule inhibitors of histone methyl transferase DOT1L with a nitrile as a non-traditional replacement for heavy halogen atoms. Bioorganic & medicinal chemistry letters, 2016, 09-15, Volume: 26, Issue:18 Topics: Crystallography; Enzyme Inhibitors; Halogens; Histone-Lysine N-Methyltransferase; Methyltransferases; Nitriles; Small Molecule Libraries; Structure-Activity Relationship	2016
Synthesis and antiviral activity of some 7-[(2-hydroxyethoxy)methyl]pyrazolo[3,4-d]pyrimidine analogues of sangivamycin and toyocamycin. Journal of medicinal chemistry, 1990, Volume: 33, Issue:7 Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Antiviral Agents; Cell Line; Cell Survival; Cytomegalovirus; Dose-Response Relationship, Drug; Humans; Indicators and Reagents; KB Cells; Molecular Structure; Pyrimidine Nucleosides; Simplexvirus; Structure-Activity Relationship; Toyocamycin; Viral Plaque Assay	1990
Nucleoside inhibitors of rhodopsin kinase. Biochemistry, 1990, Jul-03, Volume: 29, Issue:26 Topics: Adenosine; Animals; Binding Sites; Cattle; Eye Proteins; G-Protein-Coupled Receptor Kinase 1; Molecular Conformation; Nucleosides; Protein Kinase Inhibitors; Protein Kinases; Pyrimidine Nucleosides; Toyocamycin	1990
Synthesis, cytotoxicity, and antiviral activity of certain 7-[(2-hydroxyethoxy)methyl]pyrrolo[2,3-d]pyrimidine nucleosides related to toyocamycin and sangivamycin. Journal of medicinal chemistry, 1989, Volume: 32, Issue:7 Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Antiviral Agents; Cell Survival; Cells, Cultured; Chemical Phenomena; Chemistry; Haplorhini; Humans; Mice; Pyrimidine Nucleosides; Pyrroles; Toyocamycin	1989
Cytotoxicity and the inhibition of ribosomal RNA processing in human colon carcinoma cells. Molecular pharmacology, 1985, Volume: 27, Issue:2 Topics: Azacitidine; Azaguanine; Cell Survival; Cells, Cultured; Colonic Neoplasms; Fluorouracil; Humans; Protein Biosynthesis; Pyrimidine Nucleosides; RNA, Ribosomal; Toyocamycin; Tubercidin	1985
Comparison of the cellular and RNA-dependent effects of sangivamycin and toyocamycin in human colon carcinoma cells. Molecular pharmacology, 1985, Volume: 27, Issue:3 Topics: Antibiotics, Antineoplastic; Cell Survival; Colonic Neoplasms; Humans; In Vitro Techniques; Leucine; Methylation; Protein Biosynthesis; Pyrimidine Nucleosides; Ribonucleosides; RNA; RNA, Ribosomal; Time Factors; Toyocamycin; Uridine	1985
Electrochemical study of the reduction of toyocamycin and sangivamycin in aqueous media. Acta biochimica Polonica, 1987, Volume: 34, Issue:2 Topics: Aminoglycosides; Anti-Bacterial Agents; Electrolysis; Horseradish Peroxidase; Oxidation-Reduction; Photochemistry; Polarography; Pyrimidine Nucleosides; Toyocamycin	1987
Differential effects of inhibitors of purine metabolism on two trichomonad species. Biochemical pharmacology, 1984, Apr-15, Volume: 33, Issue:8 Topics: Alanine; Animals; Chromatography, High Pressure Liquid; Formycins; Glycine; Mycophenolic Acid; Purine Nucleotides; Purines; Pyrimidine Nucleosides; Species Specificity; Toyocamycin; Trichomonas vaginalis; Tritrichomonas; Tubercidin; Vidarabine	1984
Genetic and biochemical studies on mutants of CHO cells resistant to 7-deazapurine nucleosides: differences in the mechanisms of action of toyocamycin and tubercidin. Biochemical and biophysical research communications, 1984, Apr-16, Volume: 120, Issue:1 Topics: Animals; Cell Line; Cricetinae; Cricetulus; Drug Resistance; Female; Macromolecular Substances; Mutation; Ovary; Pyrimidine Nucleosides; Ribonucleosides; Toyocamycin; Tubercidin	1984
Inhibition of histone H1 phosphorylation by sangivamycin and other pyrrolopyrimidine analogues. Molecular pharmacology, 1981, Volume: 20, Issue:1 Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Nucleus; Histones; In Vitro Techniques; Mice; Phosphorylation; Protein Kinase Inhibitors; Pyrimidine Nucleosides; RNA, Neoplasm; Toyocamycin	1981
Synthesis and antiproliferative and antiviral activity of 2'-deoxy-2'-fluoroarabinofuranosyl analogs of the nucleoside antibiotics toyocamycin and sangivamycin. Journal of medicinal chemistry, 1995, Sep-29, Volume: 38, Issue:20 Topics: Antibiotics, Antineoplastic; Antiviral Agents; Arabinonucleosides; Cytomegalovirus; Herpesvirus 1, Human; HIV; Humans; KB Cells; Pyrimidine Nucleosides; Toyocamycin	1995
Synthesis of non-nucleoside analogs of toyocamycin, sangivamycin, and thiosangivamycin: the effect of certain 4- and 4,6-substituents on the antiviral activity of pyrrolo[2,3-d]pyrimidines. Journal of medicinal chemistry, 1996, Aug-30, Volume: 39, Issue:18 Topics: Antiviral Agents; Cytomegalovirus; Herpesvirus 1, Human; Humans; Pyrimidine Nucleosides; Pyrimidines; Structure-Activity Relationship; Thionucleosides; Toyocamycin	1996
Synthesis of pyrrolo[2,1-f][1,2,4]triazine C-nucleosides. Isosteres of sangivamycin, tubercidin, and toyocamycin. Carbohydrate research, 2001, Mar-09, Volume: 331, Issue:1 Topics: Antibiotics, Antineoplastic; Indicators and Reagents; Pyrimidine Nucleosides; Ribonucleosides; Spectrometry, Mass, Fast Atom Bombardment; Stereoisomerism; Toyocamycin; Triazines; Tubercidin	2001
Synthesis of 2'-beta-C-methyl toyocamycin and sangivamycin analogues as potential HCV inhibitors. Bioorganic & medicinal chemistry letters, 2005, Feb-01, Volume: 15, Issue:3 Topics: Adenosine; Antiviral Agents; Hepacivirus; Pyrimidine Nucleosides; Replicon; Structure-Activity Relationship; Toyocamycin	2005
Deciphering deazapurine biosynthesis: pathway for pyrrolopyrimidine nucleosides toyocamycin and sangivamycin. Chemistry & biology, 2008, Aug-25, Volume: 15, Issue:8 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Gene Expression Regulation, Bacterial; GTP Cyclohydrolase; Hydro-Lyases; Molecular Sequence Data; Multigene Family; Purines; Pyrimidine Nucleosides; Pyrimidines; Pyrroles; Streptomyces; Toyocamycin	2008
Cell cycle arrest and cytochrome c-mediated apoptotic induction in human lung cancer A549 cells by MCS-C2, an analogue of sangivamycin. Journal of microbiology and biotechnology, 2010, Volume: 20, Issue:2 Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Cytochromes c; Humans; Lung Neoplasms; Pyrimidine Nucleosides; Toyocamycin	2010
A Protein-derived Oxygen Is the Source of the Amide Oxygen of Nitrile Hydratases. The Journal of biological chemistry, 2016, Apr-08, Volume: 291, Issue:15 Topics: Actinomycetales; Catalytic Domain; Crystallography, X-Ray; Hydro-Lyases; Models, Molecular; Oxygen; Pyrimidine Nucleosides; Toyocamycin	2016
An Expeditious Total Synthesis of 5'-Deoxy-toyocamycin and 5'-Deoxysangivamycin. Molecules (Basel, Switzerland), 2019, Feb-19, Volume: 24, Issue:4 Topics: Glycosylation; Models, Molecular; Molecular Structure; Pyrimidine Nucleosides; Toyocamycin	2019