toxoflavin has been researched along with pyrimidinones in 63 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (11.11) | 18.7374 |
| 1990's | 5 (7.94) | 18.2507 |
| 2000's | 6 (9.52) | 29.6817 |
| 2010's | 35 (55.56) | 24.3611 |
| 2020's | 10 (15.87) | 2.80 |
| Authors | Studies |
|---|---|
| Yue, QA | 2 |
| Lin, LM; Zhao, NX | 1 |
| Buckle, KA; Kartadarma, EK | 1 |
| Aleksandrov, GG; Chernyshev, AI; Dovzhenko, SA; Esipov, SE; Kliuev, NA | 1 |
| Aleksandrov, GG; Esipov, SE | 1 |
| Antonovskiĭ, VL; Chernyshev, AI; Esipov, SE; Iakushkina, NI; Shorshnev, SV | 1 |
| Akimenko, VK; Esipov, SE; Golovchenko, NP; Medentsev, AG | 1 |
| Hirota, T; Kido, Y; Nagamatsu, T; Shibata, M; Yamasaki, H; Yamato, M; Yoneda, F | 1 |
| Ma, M; Wang, R; Wang, Z | 1 |
| BERENDS, W; LATUASAN, HE | 1 |
| Hwang, I; Jang, JY; Jog, GJ; Kang, Y; Kim, J; Kim, JG; Kim, S; Lim, JY; Nagamatsu, T; Suga, H | 1 |
| Li, J; Li, S; Liu, D; Sun, Y; Wang, S; Zhang, L; Zhang, X; Zhou, Y | 1 |
| Bigirimana, J; Cabrio, L; Degrassi, G; Devescovi, G; Hwang, I; Kim, J; LiPuma, JJ; Venturi, V | 1 |
| Chen, G; Liu, BR; Xie, L | 1 |
| Choi, O; Chun, H; Goo, E; Hwang, I; Kang, Y; Kim, H; Kim, J; Kim, N; Moon, JS | 1 |
| Choi, O; Goo, E; Hwang, I; Kang, Y; Kim, H; Kim, J; Ma, J; Moon, JS; Nagamatsu, T; Oh, J | 1 |
| Chua, MS; Grepper, S; So, S; Wei, W | 1 |
| Ee, PL; Leow, PC; Ong, ZY; Tian, Q; Yang, Z | 1 |
| Choi, O; Goo, E; Hwang, I; Jwa, NS; Kim, H; Kim, J; Kim, YJ; Koh, S; Ma, J; Moon, JS; Nagamatsu, T | 1 |
| Kim, YC; Lee, YH; Park, JY; Yang, KY | 1 |
| Begley, TP; Ealick, SE; Fenwick, MK; Philmus, B | 2 |
| Goo, E; Han, J; Hwang, I; Jung, WS; Kim, H; Kim, MI; Lee, J; Ma, J; Nagamatsu, T; Rhee, S | 1 |
| Abdelwahed, S; Begley, TP; Ealick, SE; Fenwick, MK; Philmus, B; Williams, HJ | 1 |
| Giacomelli, AO; Girgis-Gabardo, A; Hallett, RM; Hassell, JA; Ilieva, D; Kondratyev, MK; Nixon, AM | 1 |
| Barphagha, IK; Groth, DE; Ham, JH; Han, JW; Karki, HS; Kim, BS; Melanson, RA; Rush, MC; Shrestha, BK | 1 |
| Hwang, I; Jeon, JH; Joung, H; Kim, H; Kim, MS; Moon, JS | 1 |
| Barphagha, IK; Chen, R; Ham, JH; Karki, HS | 1 |
| Akan, H; Beyer, C; Dees, C; Distler, A; Distler, JH; Distler, O; Gelse, K; Lin, NY; Mallano, T; Palumbo-Zerr, K; Reichert, H; Schett, G; Schramm, A; Varga, J | 1 |
| Depledge, P; Hamilton, NM; Hamilton, NS; Hitchin, JR; Hopkins, GV; Jordan, AM; Maguire, LA; McGonagle, AE; Mould, DP; Ogilvie, DJ; Raoof, A; Rushbrooke, M; Small, HF; Smith, KM; Thomson, GJ; Turlais, F; Waddell, ID; Waszkowycz, B; Watson, AJ | 1 |
| Choi, O; Goo, E; Han, I; Hwang, I; Kim, H; Kim, J; Lee, Y | 1 |
| Cho, SY; Choi, G; Ha, JD; Han, SY; Ji, JY; Kang, NS; Kim, HR; Lee, J; Woo, J | 1 |
| Aretz, S; Büttner, R; Friedrichs, N; Hartmann, W; Huss, S; Kawai, A; Kindler, D; Kirfel, J; Koch, A; Larsson, O; Mechtersheimer, G; Michels, S; Penzel, R; Renner, M; Schirmacher, P; Sievers, E; Sonobe, H; Steiner, S; Tanaka, S; Trautmann, M; Waha, A; Wardelmann, E | 1 |
| CHARNEY, J; FISHER, WP; MACHLOWITZ, RA; McKAY, BS; TYTELL, AA | 1 |
| Ham, JH; Karki, HS | 1 |
| Barphagha, IK; Chen, R; Ham, JH | 1 |
| Kim, S; Lee, J; Park, I; Park, J; Seo, YS | 1 |
| Ayadi, M; Bouygues, A; Chouaib, S; Ferrand, N; Larsen, AK; Muchardt, C; Ouaret, D; Sabbah, M; Thiery, JP | 1 |
| Begley, TP; Kidarsa, TA; Loper, JE; Philmus, B; Raaijmakers, JM; Shaffer, BT; Yan, Q | 1 |
| Cui, HY; Jing, MD; Li, WM; Liu, ZL; Lu, B; Wang, DY; Wang, X | 1 |
| Altucci, L; Franci, G; Nebbioso, A; Sarno, F | 1 |
| Barphagha, I; Chen, R; Ham, JH; Karki, HS; Lelis, TP; Melanson, RA; Osti, S; Shrestha, BK | 1 |
| Alemany, R; Calabuig-Fariñas, S; Felipe-Abrio, I; Martín-Broto, J; Martinez-Font, E; Obrador-Hevia, A; Ramos, R; Terrasa, J; Vögler, O | 1 |
| Almonte, V; Chinnasamy, P; Egaña-Gorroño, L; Gross, JN; Guo, L; Jayakumar, S; Parikh, D; Riascos-Bernal, DF; Sibinga, NES | 1 |
| Flórez, LV; Gaube, P; Hermes, C; Hertweck, C; Kaltenpoth, M; Rodrigues, A; Ross, C; Scherlach, K; Sitte, E | 1 |
| Almabruk, KH; Begley, TP; Ealick, SE; Fenwick, MK; Philmus, B | 1 |
| Flórez, LV; Kaltenpoth, M | 1 |
| Choi, JE; Choi, JS; Kim, JC; Lee, B; Nguyen, CM; Oh, JY; Park, JH; Song, JK | 1 |
| Bartley, LE; Choi, Y; Ji, S; Jung, B; Kang, Y; Kim, BY; Kim, I; Kim, J; Kim, N; Kim, S; Kim, WC; Lee, HH; Lee, J; Lee, KS; Li, T; Liu, KH; Park, J; Seo, YS; Shon, JC; Yoon, D; Yun, K | 1 |
| Hendriks, J; Huang, X; Karperien, M; Post, JN; Zhong, L | 1 |
| Guo, X; Huang, SX; Liu, C; Luo, J; Su, C; Xiang, WS; Yan, Y; Zhang, Z | 1 |
| Jung, H; Lee, HH; Park, J; Seo, YS | 1 |
| Bokulić, A; Jelić, D; Koštrun, S; Letfus, V; Petrinić Grba, A | 1 |
| Bin, L; Bo, Z; Hong, X; Hussain, A; Ibrahim, M; Khalid, Z; Naeem, F; Raza, HMZ; Shahbaz, M; Tariq, M | 1 |
| Choi, O; Kang, B; Kim, J; Lee, Y | 2 |
| Choi, O; Chun, HJ; Kang, B; Kim, J; Kim, MC; Lee, Y; Park, J | 1 |
| Bruno, J; Doerrler, WT; Ham, JH; Iqbal, A; Ontoy, J; Panta, PR | 1 |
| Bédard, É; Déziel, E; Faucher, SP; Matthews, S; Nickzad, A; Paranjape, K; Prévost, M; Shetty, D; Vounba, P | 1 |
| Meirelles, LA; Newman, DK | 1 |
| Chang, X; Cui, X; Hu, L; Hu, Y; Wang, H; Zhang, Y; Zhou, P | 1 |
| Du, YL; He, HY; Li, H; Li, W; Liu, Y; Song, K; Zhao, G; Zhao, Z | 1 |
1 review(s) available for toxoflavin and pyrimidinones
| Article | Year |
|---|---|
[Stem cell-targeted therapy--a new strategy for cancer treatment].
Topics: Adenosine; Animals; Antineoplastic Agents; ATP-Binding Cassette Transporters; Biomarkers, Tumor; Cell Differentiation; Diketopiperazines; Heterocyclic Compounds, 4 or More Rings; Humans; Lapatinib; Neoplasms; Neoplastic Stem Cells; Protein Kinase Inhibitors; Pyrimidinones; Quinazolines; Signal Transduction; Triazines; Wnt Proteins | 2008 |
62 other study(ies) available for toxoflavin and pyrimidinones
| Article | Year |
|---|---|
[Study of toxication of toxoflavin from Pseudomonas cocovenenans to immunocyte and detoxication].
Topics: Animals; Antidotes; Cell Division; Cytochrome c Group; Glutathione; Lymphocytes; Pseudomonas; Pyrimidinones; Rabbits; Superoxide Dismutase; Triazines | 1992 |
Simultaneous determination of toxic metabolites by linear combination derivative spectrophotometry.
Topics: Bongkrekic Acid; Food Contamination; Pseudomonas; Pyrimidinones; Spectrophotometry, Ultraviolet; Triazines | 1991 |
Inhibition of bongkrek acid and toxoflavin production in tempe bongkrek containing Pseudomonas cocovenenans.
Topics: Acetates; Acetic Acid; Anti-Bacterial Agents; Bacterial Toxins; Bongkrekic Acid; Chromatography, High Pressure Liquid; Cocos; Fermentation; Food Microbiology; Hydrogen-Ion Concentration; Pseudomonas; Pyrimidinones; Rhizopus; Sodium Chloride; Triazines | 1990 |
[Study on mutagenicity of Toxoflavin from Pseudomonas farinofermentans].
Topics: Animals; Anti-Bacterial Agents; Bongkrekic Acid; Female; Fermentation; Flour; Male; Mice; Micronucleus Tests; Pseudomonas; Pyrimidinones; Triazines | 1989 |
[Structure of the reaction adduct of xanthothricin with acetone].
Topics: Acetone; Chromatography, Thin Layer; Drug Interactions; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylation; Pyrimidinones; Triazines; X-Ray Diffraction | 1988 |
[X-ray structural study of the pyrimido-[5,4-e]-1,2,4-triazine antibiotics xanthothricin and fervenulin].
Topics: Chemical Phenomena; Chemistry; Pyrimidinones; Triazines; X-Ray Diffraction | 1986 |
[Study of the stability of pyrimido-[5,4-e]-1,2,4-triazine antibiotics in acid-base media by NMR spectroscopy].
Topics: Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Drug Stability; Hydrogen-Ion Concentration; In Vitro Techniques; Magnetic Resonance Spectroscopy; Pyrimidinones; Spectrum Analysis; Triazines | 1985 |
Effect of xanthothricin on the respiratory chain.
Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antimycin A; Candida; Carcinoma, Ehrlich Tumor; Cyanides; Electron Transport; Hydrogen-Ion Concentration; Ketoglutaric Acids; Malonates; Mitochondria; Mitochondria, Liver; NAD; Oxidation-Reduction; Oxygen Consumption; Phenylhydrazines; Polarography; Potentiometry; Pyrimidinones; Rats; Rotenone; Species Specificity; Spectrometry, Fluorescence; Succinates; Triazines | 1974 |
Syntheses of 3-substituted 1-methyl-6-phenylpyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-diones (6-phenyl analogs of toxoflavin) and their 4-oxides, and evaluation of antimicrobial activity of toxoflavins and their analogs.
Topics: Anti-Bacterial Agents; Bacteria; Fungi; Microbial Sensitivity Tests; Pyrimidinones; Triazines | 1993 |
Enhanced vasocontraction of rat tail arteries by toxoflavin.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arteries; Caffeine; Calcium; Calcium Channels; Free Radical Scavengers; In Vitro Techniques; Isometric Contraction; Male; Muscle, Smooth, Vascular; Phenylephrine; Potassium Chloride; Prostaglandin Endoperoxides, Synthetic; Pyrimidinones; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Tail; Thromboxane A2; Triazines; Vasoconstriction; Vasoconstrictor Agents | 1996 |
On the origin of the toxicity of toxoflavin.
Topics: Anti-Bacterial Agents; Dermatologic Agents; Heterocyclic Compounds; Pseudomonas; Pyrimidinones; Triazines | 1961 |
Quorum sensing and the LysR-type transcriptional activator ToxR regulate toxoflavin biosynthesis and transport in Burkholderia glumae.
Topics: Bacterial Proteins; Biological Transport; Burkholderia; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Genes, Reporter; Multiprotein Complexes; Operon; Oryza; Pyrimidinones; Recombinant Fusion Proteins; Signal Transduction; Transcription Factors; Triazines | 2004 |
Study on glycosylated prodrugs of toxoflavins for antibody-directed enzyme tumor therapy.
Topics: Antibodies; beta-Galactosidase; Glycosides; Immunotherapy; Magnetic Resonance Spectroscopy; Neoplasms; Prodrugs; Pyrimidinones; Triazines | 2007 |
Involvement of a quorum-sensing-regulated lipase secreted by a clinical isolate of Burkholderia glumae in severe disease symptoms in rice.
Topics: Bacterial Proteins; Burkholderia; Burkholderia Infections; Gene Expression Regulation, Bacterial; Humans; Lipase; Molecular Sequence Data; Oryza; Plant Diseases; Pyrimidinones; Quorum Sensing; Sequence Analysis, DNA; Triazines | 2007 |
The quorum sensing-dependent gene katG of Burkholderia glumae is important for protection from visible light.
Topics: Bacterial Proteins; Burkholderia; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Bacterial; Light; Microbial Viability; Mutation; Oryza; Pyrimidinones; Quorum Sensing; Triazines | 2009 |
Biochemical evidence for ToxR and ToxJ binding to the tox operons of Burkholderia glumae and mutational analysis of ToxR.
Topics: Bacterial Proteins; Binding Sites; Burkholderia; Chromatography, Gel; DNA Footprinting; DNA Mutational Analysis; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Bacterial; Molecular Structure; Mutagenesis; Operon; Protein Binding; Protein Multimerization; Pyrimidinones; Quorum Sensing; Transcription Factors; Triazines | 2009 |
Small molecule antagonists of Tcf4/beta-catenin complex inhibit the growth of HCC cells in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; beta Catenin; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cyclin D1; Dose-Response Relationship, Drug; Down-Regulation; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Genes, myc; Hepatocytes; Humans; Immunohistochemistry; Inhibitor of Apoptosis Proteins; Liver Neoplasms; Mice; Mice, Nude; Microtubule-Associated Proteins; Perylene; Pyrimidinones; Random Allocation; Signal Transduction; Survivin; Transcription Factor 4; Transcription Factors; Triazines; Wnt Proteins; Xenograft Model Antitumor Assays | 2010 |
Antitumor activity of natural compounds, curcumin and PKF118-310, as Wnt/β-catenin antagonists against human osteosarcoma cells.
Topics: Antineoplastic Agents; beta Catenin; Biological Products; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Cell Survival; Curcumin; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Humans; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Osteosarcoma; Pyrimidinones; Signal Transduction; Triazines; Wnt Proteins | 2010 |
A novel light-dependent selection marker system in plants.
Topics: Arabidopsis; Biomarkers; Cinnamates; Genes, Bacterial; Genetic Techniques; Hygromycin B; Light; Oryza; Paenibacillus; Phosphotransferases (Alcohol Group Acceptor); Plant Leaves; Plants; Plants, Genetically Modified; Pyrimidinones; Recombinant Fusion Proteins; Transformation, Genetic; Triazines | 2011 |
AiiA-mediated quorum quenching does not affect virulence or toxoflavin expression in Burkholderia glumae SL2376.
Topics: Bacterial Proteins; Burkholderia; Carboxylic Ester Hydrolases; Cloning, Molecular; Gene Expression Regulation, Bacterial; Metalloendopeptidases; Operon; Oryza; Pectobacterium carotovorum; Plant Diseases; Promoter Regions, Genetic; Pyrimidinones; Quorum Sensing; Seedlings; Transformation, Genetic; Triazines; Virulence; Virulence Factors | 2010 |
Toxoflavin lyase requires a novel 1-His-2-carboxylate facial triad.
Topics: Bacterial Proteins; Binding Sites; Carboxylic Acids; Catalysis; Crystallography, X-Ray; Histidine; Hydrogen Bonding; Ligands; Lyases; Models, Molecular; Oxygen; Pyrimidinones; Triazines | 2011 |
Structural and functional analysis of phytotoxin toxoflavin-degrading enzyme.
Topics: Amino Acid Sequence; Bacterial Proteins; Biocatalysis; Catalytic Domain; Crystallography, X-Ray; Models, Molecular; Molecular Sequence Data; Paenibacillus; Pyrimidinones; Toxins, Biological; Triazines | 2011 |
Identification of the product of toxoflavin lyase: degradation via a Baeyer-Villiger oxidation.
Topics: Lyases; Manganese; Models, Molecular; Molecular Structure; Oxidation-Reduction; Oxygen; Pyrimidinones; Triazines | 2012 |
Small molecule antagonists of the Wnt/β-catenin signaling pathway target breast tumor-initiating cells in a Her2/Neu mouse model of breast cancer.
Topics: Animals; beta Catenin; Breast Neoplasms; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Epithelial Cells; Female; Gene Expression Profiling; Mammary Glands, Animal; Mice; Neoplastic Stem Cells; Pyrimidinones; Receptor, ErbB-2; Triazines; Wnt Proteins; Wnt Signaling Pathway | 2012 |
Diversities in virulence, antifungal activity, pigmentation and DNA fingerprint among strains of Burkholderia glumae.
Topics: Antifungal Agents; Burkholderia; DNA Fingerprinting; Onions; Pigmentation; Pyrimidinones; Rhizoctonia; Triazines; Virulence | 2012 |
Toxoflavin lyase enzyme as a marker for selecting potato plant transformants.
Topics: Genetic Engineering; Genetic Markers; Lyases; Pyrimidinones; Solanum tuberosum; Transformation, Genetic; Triazines | 2012 |
Dissection of quorum-sensing genes in Burkholderia glumae reveals non-canonical regulation and the new regulatory gene tofM for toxoflavin production.
Topics: Burkholderia; Gene Expression Regulation, Bacterial; Pyrimidinones; Quorum Sensing; Triazines | 2012 |
Blockade of canonical Wnt signalling ameliorates experimental dermal fibrosis.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Fibrosis; Mice; Mice, Inbred DBA; Pyrimidinones; Scleroderma, Systemic; Signal Transduction; Skin; Skin Diseases; Treatment Outcome; Triazines; Wnt Signaling Pathway | 2013 |
Toxoflavins and deazaflavins as the first reported selective small molecule inhibitors of tyrosyl-DNA phosphodiesterase II.
Topics: Phosphoric Diester Hydrolases; Pyrimidinones; Structure-Activity Relationship; Topoisomerase II Inhibitors; Triazines | 2013 |
A simple and sensitive biosensor strain for detecting toxoflavin using β-galactosidase activity.
Topics: beta-Galactosidase; Biosensing Techniques; Burkholderia; Lac Operon; Oryza; Pyrimidinones; Quorum Sensing; Triazines | 2013 |
Discovery of a potent small molecule SIRT1/2 inhibitor with anticancer effects.
Topics: Acetylation; Antineoplastic Agents; Benzamides; Cell Line, Tumor; Humans; Neoplasms; Pyrimidinones; Sirtuin 1; Sirtuin 2; Small Molecule Libraries; Structure-Activity Relationship; Triazines; Tubulin | 2013 |
SS18-SSX fusion protein-induced Wnt/β-catenin signaling is a therapeutic target in synovial sarcoma.
Topics: Animals; Antineoplastic Agents; beta Catenin; Cell Line, Tumor; Cell Nucleus; Cell Survival; Gene Expression; HEK293 Cells; Humans; Male; Mice, Inbred BALB C; Mice, Nude; Oncogene Proteins, Fusion; Perylene; Pyrimidinones; Sarcoma, Synovial; Triazines; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2014 |
Xanthothricin, a new antibiotic.
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Dermatologic Agents; Humans; Pyrimidinones; Triazines | 1954 |
The roles of the shikimate pathway genes, aroA and aroB, in virulence, growth and UV tolerance of Burkholderia glumae strain 411gr-6.
Topics: Adaptation, Physiological; Burkholderia; Genes, Bacterial; Glycine; Glyphosate; Metabolic Networks and Pathways; Microbial Viability; Mutation; Onions; Oryza; Pigments, Biological; Plant Diseases; Pyrimidinones; Shikimic Acid; Triazines; Ultraviolet Rays; Virulence | 2014 |
Identification of potential genetic components involved in the deviant quorum-sensing signaling pathways of Burkholderia glumae through a functional genomics approach.
Topics: Bacterial Proteins; Burkholderia; Gene Expression Regulation, Bacterial; Genomics; Onions; Plant Diseases; Pyrimidinones; Quorum Sensing; Signal Transduction; Triazines; Virulence | 2015 |
Differential regulation of toxoflavin production and its role in the enhanced virulence of Burkholderia gladioli.
Topics: Biosynthetic Pathways; Burkholderia gladioli; Genes, Bacterial; Genetic Complementation Test; Movement; Onions; Operon; Pyrimidinones; Reproducibility of Results; Triazines; Virulence | 2016 |
Chronic chemotherapeutic stress promotes evolution of stemness and WNT/beta-catenin signaling in colorectal cancer cells: implications for clinical use of WNT-signaling inhibitors.
Topics: Antineoplastic Agents; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Camptothecin; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Hyaluronan Receptors; Irinotecan; Neoplastic Stem Cells; Organoplatinum Compounds; Oxaliplatin; Protein Isoforms; Pyrimidinones; Reverse Transcriptase Polymerase Chain Reaction; Triazines; Wnt Signaling Pathway | 2015 |
Investigations into the Biosynthesis, Regulation, and Self-Resistance of Toxoflavin in Pseudomonas protegens Pf-5.
Topics: Biosynthetic Pathways; Chromatography, Liquid; Cloning, Molecular; Molecular Structure; Multigene Family; Pseudomonas; Pyrimidinones; Triazines | 2015 |
[Effect of PKF118-310 on Cell Cycle and Proliferation of K562 Cells and Its Mechanism].
Topics: beta Catenin; Caspase 3; Cell Cycle; Cell Proliferation; Humans; K562 Cells; Pyrimidinones; Triazines | 2015 |
Burkholderia glumae ToxA Is a Dual-Specificity Methyltransferase That Catalyzes the Last Two Steps of Toxoflavin Biosynthesis.
Topics: Bacterial Proteins; Burkholderia; Catalysis; Catalytic Domain; Crystallography, X-Ray; Methylation; Methyltransferases; Protein Structure, Secondary; Pyrimidinones; Triazines | 2016 |
Identification and characterization of PKF118-310 as a KDM4A inhibitor.
Topics: Apoptosis; beta Catenin; Cell Proliferation; Colorectal Neoplasms; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; HCT116 Cells; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Molecular Docking Simulation; Pyrimidinones; Triazines | 2017 |
Identification of new regulatory genes involved in the pathogenic functions of the rice-pathogenic bacterium Burkholderia glumae.
Topics: Base Sequence; Burkholderia; DNA Transposable Elements; DNA, Bacterial; Gene Expression Regulation, Bacterial; Genes, Regulator; Lipase; Mutagenesis; Mutation; Oryza; Phenotype; Plant Diseases; Polysaccharides, Bacterial; Pyrimidinones; Quorum Sensing; Sequence Analysis, DNA; Triazines; Virulence Factors | 2017 |
Disruption of TCF/β-Catenin Binding Impairs Wnt Signaling and Induces Apoptosis in Soft Tissue Sarcoma Cells.
Topics: Antineoplastic Agents; Apoptosis; beta Catenin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Doxorubicin; Drug Synergism; Humans; Protein Binding; Pyrimidinones; Sarcoma; TCF Transcription Factors; Triazines; Wnt Signaling Pathway | 2017 |
Inhibition of Smooth Muscle β-Catenin Hinders Neointima Formation After Vascular Injury.
Topics: Animals; Apoptosis; beta Catenin; Bridged Bicyclo Compounds, Heterocyclic; Carotid Arteries; Carotid Artery Injuries; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Genotype; Humans; Male; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; Phenotype; Pyrimidinones; Signal Transduction; Time Factors; Triazines; Vascular Remodeling | 2017 |
Antibiotic-producing symbionts dynamically transition between plant pathogenicity and insect-defensive mutualism.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Burkholderia gladioli; Coleoptera; Fungi; Glycine max; In Situ Hybridization, Fluorescence; Pyrimidinones; Symbiosis; Triazines | 2017 |
Biochemical Characterization and Structural Basis of Reactivity and Regioselectivity Differences between Burkholderia thailandensis and Burkholderia glumae 1,6-Didesmethyltoxoflavin N-Methyltransferase.
Topics: Bacterial Proteins; Binding Sites; Burkholderia; Catalytic Domain; Crystallography, X-Ray; Histidine; Hydrogen Bonding; Methylation; Methyltransferases; Models, Molecular; Multigene Family; Oxidation-Reduction; Phylogeny; Protein Conformation; Pyrimidinones; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Species Specificity; Stereoisomerism; Triazines | 2017 |
Symbiont dynamics and strain diversity in the defensive mutualism between Lagria beetles and Burkholderia.
Topics: Animals; Antibiosis; Biological Evolution; Burkholderia; Coleoptera; Female; Fungi; Larva; Male; Phylogeny; Pyrimidinones; Symbiosis; Triazines | 2017 |
Isolation and characterization of a novel metagenomic enzyme capable of degrading bacterial phytotoxin toxoflavin.
Topics: Amino Acid Sequence; Bacterial Toxins; Burkholderia; Enzymes; Metagenomics; Pyrimidinones; Sequence Homology, Amino Acid; Triazines | 2018 |
Cooperative interactions between seed-borne bacterial and air-borne fungal pathogens on rice.
Topics: Air Microbiology; Burkholderia; Drug Resistance, Fungal; Fusarium; Gene Expression Profiling; Gene Expression Regulation, Fungal; Host-Pathogen Interactions; Microbial Interactions; Mutation; Oryza; Phylogeny; Plant Diseases; Pyrimidinones; Seeds; Triazines | 2018 |
The Effects of the WNT-Signaling Modulators BIO and PKF118-310 on the Chondrogenic Differentiation of Human Mesenchymal Stem Cells.
Topics: Cell Differentiation; Cells, Cultured; Chondrocytes; Collagen; HEK293 Cells; Humans; Indoles; Matrix Metalloproteinases; Mesenchymal Stem Cells; Oximes; Pyrimidinones; Transcription Factors; Triazines; Wnt Signaling Pathway | 2018 |
Characterization of the N-methyltransferases involved in the biosynthesis of toxoflavin, fervenulin and reumycin from Streptomyces hiroshimensis ATCC53615.
Topics: Biocatalysis; Dose-Response Relationship, Drug; Methyltransferases; Molecular Structure; Pyrimidinones; Streptomyces; Structure-Activity Relationship; Triazines | 2019 |
Transcriptome analysis to understand the effects of the toxoflavin and tropolone produced by phytopathogenic Burkholderia on Escherichia coli.
Topics: Anti-Bacterial Agents; Burkholderia; Escherichia coli; Escherichia coli Proteins; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Oryza; Plant Diseases; Pyrimidinones; Transcriptome; Triazines; Tropolone | 2019 |
Rational design, synthesis and biological profiling of new KDM4C inhibitors.
Topics: A549 Cells; Animals; Dogs; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Humans; Jumonji Domain-Containing Histone Demethylases; Madin Darby Canine Kidney Cells; Mice; Microsomes, Liver; Molecular Structure; Pyrimidinones; Quantum Theory; Structure-Activity Relationship; Triazines | 2020 |
Genome re-seqeunce and analysis of Burkholderia glumae strain AU6208 and evidence of toxoflavin: A potential bacterial toxin.
Topics: Bacterial Proteins; Bacterial Toxins; Burkholderia; Genome, Bacterial; Pyrimidinones; Triazines | 2020 |
Pantoea ananatis carotenoid production confers toxoflavin tolerance and is regulated by Hfq-controlled quorum sensing.
Topics: Bacterial Proteins; Carotenoids; Endopeptidase Clp; Escherichia coli; Escherichia coli Proteins; Host Factor 1 Protein; Multigene Family; Pantoea; Plasmids; Pyrimidinones; Quorum Sensing; Sigma Factor; Triazines; Ultraviolet Rays | 2021 |
A novel toxoflavin-quenching regulation in bacteria and its application to resistance cultivars.
Topics: Burkholderia; Ecosystem; Gene Expression Regulation, Bacterial; Oryza; Pyrimidinones; Quorum Sensing; Sphingomonas; Triazines | 2021 |
Chemical or Genetic Alteration of Proton Motive Force Results in Loss of Virulence of Burkholderia glumae, the Cause of Rice Bacterial Panicle Blight.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Burkholderia; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Onions; Oryza; Plant Diseases; Proton-Motive Force; Pyrimidinones; Sodium Bicarbonate; Triazines; Virulence; Virulence Factors | 2021 |
Toxoflavin secreted by Pseudomonas alcaliphila inhibits the growth of Legionella pneumophila and Vermamoeba vermiformis.
Topics: Humans; Legionella; Legionella pneumophila; Phylogeny; Pseudomonas; Pyrimidinones; RNA, Ribosomal, 16S; Triazines; Water; Water Microbiology | 2022 |
Phenazines and toxoflavin act as interspecies modulators of resilience to diverse antibiotics.
Topics: Anti-Bacterial Agents; Burkholderia cepacia complex; Humans; Phenazines; Pseudomonas aeruginosa; Pyocyanine; Pyrimidinones; Triazines | 2022 |
Determination of bacterial toxin toxoflavin and fervenulin in food and identification of their degradation products.
Topics: Bacterial Toxins; Chromatography, High Pressure Liquid; Pyrimidinones; Tandem Mass Spectrometry; Triazines | 2023 |
Toxoflavin contamination in rice samples from rice processing complexes in South Korea.
Topics: Oryza; Pyrimidinones; Quorum Sensing; RNA, Ribosomal, 16S | 2023 |
Heterologous Reconstitution of Toxoflavin Biosynthesis Reveals Key Pathway Intermediates and a Cofactor-Independent Oxidase.
Topics: Escherichia coli; Oxidoreductases; Pyrimidinones; Triazines | 2023 |