Page last updated: 2024-08-23

torpedo and galantamine

torpedo has been researched along with galantamine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's5 (45.45)29.6817
2010's5 (45.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Greenblatt, HM; Kryger, G; Lewis, T; Silman, I; Sussman, JL1
Bartolucci, C; Fels, G; Lamba, D; Perola, E; Pilger, C1
Bartolucci, C; Fels, G; Lamba, D; Pilger, C; Tropsha, A1
Argaman, A; Badet, B; Botti, S; Greenblatt, HM; Guénard, D; Guillou, C; Silman, I; Sussman, JL; Thal, C1
Aleu, J; López, S; Marsal, J; Martín-Satué, M; Ros, E; Solsona, C; Texidó, L1
Bamba, el HS; Galland, N; Koné, S; Le Questel, JY1
Bartolucci, C; Fels, G; Haller, LA; Jordis, U; Lamba, D1
Shan, WG; Wang, ZL; Yu, Q; Zhan, ZJ1
Cohen, JB; Hamouda, AK; Kimm, T1
Ali, MA; Basiri, A; Kia, Y; Kumar, RS; Murugaiyah, V; Osman, H1
Ali, MR; Boutajangout, A; Mezei, M; Møller, SG; Sadoqi, M1

Other Studies

11 other study(ies) available for torpedo and galantamine

ArticleYear
Structure of acetylcholinesterase complexed with (-)-galanthamine at 2.3 A resolution.
    FEBS letters, 1999, Dec-17, Volume: 463, Issue:3

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Binding Sites; Cholinesterase Inhibitors; Drug Design; Galantamine; Galanthus; Hydrogen Bonding; Molecular Structure; Stereoisomerism; Torpedo; X-Ray Diffraction

1999
Three-dimensional structure of a complex of galanthamine (Nivalin) with acetylcholinesterase from Torpedo californica: implications for the design of new anti-Alzheimer drugs.
    Proteins, 2001, Feb-01, Volume: 42, Issue:2

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Binding Sites; Cholinesterase Inhibitors; Crystallization; Crystallography, X-Ray; Cyclohexanes; Cyclohexenes; Drug Design; Galantamine; Models, Molecular; Nootropic Agents; Protein Conformation; Structure-Activity Relationship; Torpedo

2001
Accurate prediction of the bound conformation of galanthamine in the active site of Torpedo californica acetylcholinesterase using molecular docking.
    Journal of molecular graphics & modelling, 2001, Volume: 19, Issue:3-4

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Catalytic Domain; Cholinesterase Inhibitors; Computer Simulation; Crystallography, X-Ray; Galantamine; Humans; Models, Molecular; Molecular Conformation; Nootropic Agents; Protein Conformation; Software; Torpedo

2001
The complex of a bivalent derivative of galanthamine with torpedo acetylcholinesterase displays drastic deformation of the active-site gorge: implications for structure-based drug design.
    Journal of the American Chemical Society, 2004, Dec-01, Volume: 126, Issue:47

    Topics: Acetylcholinesterase; Animals; Binding Sites; Cholinesterase Inhibitors; Crystallography, X-Ray; Electrophorus; Galantamine; Inhibitory Concentration 50; Kinetics; Models, Molecular; Structure-Activity Relationship; Torpedo

2004
Effect of galantamine on the human alpha7 neuronal nicotinic acetylcholine receptor, the Torpedo nicotinic acetylcholine receptor and spontaneous cholinergic synaptic activity.
    British journal of pharmacology, 2005, Volume: 145, Issue:5

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Cholinesterase Inhibitors; Female; Galantamine; Humans; In Vitro Techniques; Membrane Potentials; Nootropic Agents; Oocytes; Parasympathetic Nervous System; Patch-Clamp Techniques; Receptors, Nicotinic; Synapses; Synaptic Transmission; Torpedo; Xenopus laevis

2005
Hydrogen-bonding properties of galanthamine: an investigation through crystallographic database observations and computational chemistry.
    Acta crystallographica. Section B, Structural science, 2008, Volume: 64, Issue:Pt 3

    Topics: Animals; Computer Simulation; Crystallography, X-Ray; Databases, Protein; Galantamine; Hydrogen Bonding; Models, Chemical; Models, Molecular; Models, Theoretical; Molecular Conformation; Quaternary Ammonium Compounds; Software; Static Electricity; Thermodynamics; Torpedo

2008
Probing Torpedo californica acetylcholinesterase catalytic gorge with two novel bis-functional galanthamine derivatives.
    Journal of medicinal chemistry, 2010, Jan-28, Volume: 53, Issue:2

    Topics: Acetylcholinesterase; Animals; Catalytic Domain; Crystallography, X-Ray; Galantamine; Molecular Probes; Piperidines; Protein Binding; Structure-Activity Relationship; Torpedo

2010
Indole alkaloids from Ervatamia hainanensis with potent acetylcholinesterase inhibition activities.
    Bioorganic & medicinal chemistry letters, 2010, Nov-01, Volume: 20, Issue:21

    Topics: Acetylcholinesterase; Alkaloids; Animals; Apocynaceae; Cholinesterase Inhibitors; Galantamine; Hydrogen Bonding; Indoles; Models, Molecular; Molecular Conformation; Torpedo; X-Ray Diffraction

2010
Physostigmine and galanthamine bind in the presence of agonist at the canonical and noncanonical subunit interfaces of a nicotinic acetylcholine receptor.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Jan-09, Volume: 33, Issue:2

    Topics: Algorithms; Animals; Binding Sites; Cholinergic Agonists; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Galantamine; Hydrolysis; In Vitro Techniques; Ion Channels; Models, Molecular; Peptide Hydrolases; Photochemistry; Physostigmine; Polymerase Chain Reaction; Radioligand Assay; Receptors, GABA-A; Receptors, Nicotinic; Torpedo

2013
Microwave assisted synthesis, cholinesterase enzymes inhibitory activities and molecular docking studies of new pyridopyrimidine derivatives.
    Bioorganic & medicinal chemistry, 2013, Jun-01, Volume: 21, Issue:11

    Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Galantamine; Humans; Microwaves; Molecular Docking Simulation; Pyrimidines; Structure-Activity Relationship; Torpedo

2013
Assessing the binding of cholinesterase inhibitors by docking and molecular dynamics studies.
    Journal of molecular graphics & modelling, 2017, Volume: 76

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Hydrogen Bonding; Indans; Molecular Conformation; Molecular Dynamics Simulation; Piperidines; Rivastigmine; Torpedo

2017