Page last updated: 2024-09-04

torcetrapib and 3-((3-(4-chloro-3-ethylphenoxy)phenyl)(3-(1,1,2,2-tetrafluoroethoxy)benzyl)amino)-1,1,1-trifluoropropan-2-ol

torcetrapib has been researched along with 3-((3-(4-chloro-3-ethylphenoxy)phenyl)(3-(1,1,2,2-tetrafluoroethoxy)benzyl)amino)-1,1,1-trifluoropropan-2-ol in 2 studies

Compound Research Comparison

Studies (torcetrapib)	Trials (torcetrapib)	Recent Studies (post-2010) (torcetrapib)	Studies (3-((3-(4-chloro-3-ethylphenoxy)phenyl)(3-(1,1,2,2-tetrafluoroethoxy)benzyl)amino)-1,1,1-trifluoropropan-2-ol)	Trials (3-((3-(4-chloro-3-ethylphenoxy)phenyl)(3-(1,1,2,2-tetrafluoroethoxy)benzyl)amino)-1,1,1-trifluoropropan-2-ol)	Recent Studies (post-2010) (3-((3-(4-chloro-3-ethylphenoxy)phenyl)(3-(1,1,2,2-tetrafluoroethoxy)benzyl)amino)-1,1,1-trifluoropropan-2-ol)
273	28	83	5	0	1

Protein Interaction Comparison

Protein	Taxonomy	torcetrapib (IC50)	3-((3-(4-chloro-3-ethylphenoxy)phenyl)(3-(1,1,2,2-tetrafluoroethoxy)benzyl)amino)-1,1,1-trifluoropropan-2-ol (IC50)
Cholesteryl ester transfer protein	Homo sapiens (human)		0.0213
Cholesteryl ester transfer protein	Oryctolagus cuniculus (rabbit)		0.03

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Connelly, MA; Damiano, BP; Demarest, KT; Gibbs, AC; Kuo, GH; Murray, WV; Pelton, P; Rano, T	1
Garda, HA; Gonzalez, MC; Tárraga, WA; Toledo, JD	1

Other Studies

2 other study(ies) available for torcetrapib and 3-((3-(4-chloro-3-ethylphenoxy)phenyl)(3-(1,1,2,2-tetrafluoroethoxy)benzyl)amino)-1,1,1-trifluoropropan-2-ol

Article	Year
Design, synthesis, and biological evaluation of (2R,alphaS)-3,4-dihydro-2-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]-5-[3-(trifluoromethoxy)-phenyl]-alpha-(trifluoromethyl)-1(2H)-quinolineethanol as potent and orally active cholesteryl ester transfer protein i Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Administration, Oral; Animals; Cholesterol Ester Transfer Proteins; Cricetinae; Dietary Fats; Drug Design; Humans; Macaca fascicularis; Magnetic Resonance Spectroscopy; Mice; Quinolines; Spectrometry, Mass, Electrospray Ionization	2009
Potential Inhibitors of the Activity of the Cholesterol-Ester Transfer Protein. Journal of computational biology : a journal of computational molecular cell biology, 2019, Volume: 26, Issue:12 Topics: Aniline Compounds; Area Under Curve; Buffers; Cholesterol Ester Transfer Proteins; Crystallization; Databases, Chemical; Humans; Inhibitory Concentration 50; Ligands; Molecular Docking Simulation; Propanolamines; Quinolines; ROC Curve; Serum	2019

Article

Year

Design, synthesis, and biological evaluation of (2R,alphaS)-3,4-dihydro-2-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]-5-[3-(trifluoromethoxy)-phenyl]-alpha-(trifluoromethyl)-1(2H)-quinolineethanol as potent and orally active cholesteryl ester transfer protein i

Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

Topics: Administration, Oral; Animals; Cholesterol Ester Transfer Proteins; Cricetinae; Dietary Fats; Drug Design; Humans; Macaca fascicularis; Magnetic Resonance Spectroscopy; Mice; Quinolines; Spectrometry, Mass, Electrospray Ionization

2009

Potential Inhibitors of the Activity of the Cholesterol-Ester Transfer Protein.

Journal of computational biology : a journal of computational molecular cell biology, 2019, Volume: 26, Issue:12

Topics: Aniline Compounds; Area Under Curve; Buffers; Cholesterol Ester Transfer Proteins; Crystallization; Databases, Chemical; Humans; Inhibitory Concentration 50; Ligands; Molecular Docking Simulation; Propanolamines; Quinolines; ROC Curve; Serum

2019