Page last updated: 2024-08-24

torbafylline and pentoxifylline

torbafylline has been researched along with pentoxifylline in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19903 (9.68)18.7374
1990's24 (77.42)18.2507
2000's3 (9.68)29.6817
2010's1 (3.23)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Egginton, S; Hudlicka, O2
Aboudrar, S; Desplanches, D; Favier, R; Graber-von Bergen, F; Hoppeler, H; Okyayuz-Baklouti, I1
Emeis, JJ; Tranquille, N1
Schmid-Schönbein, GW; Wong, PM1
Bergren, DR; Bergren, VA; Bewtra, AK; Eda, R; Gang, W; Hopp, RJ; Sugiyama, H; Townley, RG1
Berens, KL; Langston, JD; Luke, DR; Wasan, KM1
Berens, KL; Brunner, LJ; Lopez-Berestein, G; Luke, DR; Vadiei, K; Verani, RR; Wasan, KM1
Dawson, JM; Hudlickà, O; Okyayuz-Baklouti, I1
Hudlická, O; Price, S1
Hudlicka, O; Torres, SH1
Dinn, RF; Terjung, RL; Yang, HT1
Schade, UF; Schönharting, M; von der Bosch, J1
Schade, UF1
Okyayuz-Baklouti, I1
Blöhmer, A; Hänel, H; Heidemann, HT; Inselmann, G; Kottny, W; Nellessen, U1
Hand, DL; Hand, WL1
Covington, SJ; Ford, DM; Lamp, CA; Molitoris, BA; Thieme, RE1
Brown, MD; Egginton, S; Hudlicka, O; Okyayuz-Baklouti, I1
Lagarde, M; Meskini, N; Némoz, G; Okyayuz-Baklouti, I; Prigent, AF1
Lucas-Héron, B; Ollivier, B; Schmitt, N1
Alléra, A; Eisenhut, T; Endres, S; Gebert, U; Moeller, J; Schönharting, MM; Semmler, J1
Egginton, S; Glover, M; Hudlicka, O1
Koch, H; Kogler, H; Leibfritz, D; Norris, D; Okyayuz-Baklouti, I1
Bendtzen, K; Jakobsen, PH; Koch, C1
Berens, KL; Luke, DR; Verani, RR1
Kelleher, DK; Thews, O; Vaupel, P1
Attaix, D; Claustre, A; Combaret, L; Obled, C; Taillandier, D; Tanaka, K; Tilignac, T; Voisin, L1
Ellmén, J; Hakulinen, P; Hayes, DF; Partanen, A1
Booth, FW; Lees, SJ; Steffen, BT1
Balasubramaniam, A; Friend, LA; James, JH; Joshi, R; Kadeer, N; Sheriff, S1

Trials

1 trial(s) available for torbafylline and pentoxifylline

ArticleYear
Estrogenic effects of toremifene and tamoxifen in postmenopausal breast cancer patients.
    Breast cancer research and treatment, 2003, Volume: 82, Issue:2

    Topics: Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Antithrombin III; Aspartate Aminotransferases; Breast Neoplasms; Central Nervous System Diseases; Estradiol; Female; Follicle Stimulating Hormone; Humans; Hypercalcemia; Luteinizing Hormone; Middle Aged; Pentoxifylline; Postmenopause; Sex Hormone-Binding Globulin; Tamoxifen; Treatment Outcome; Vagina

2003

Other Studies

30 other study(ies) available for torbafylline and pentoxifylline

ArticleYear
Regional capillary perfusion in muscles with limited blood supply: effects of torbafylline.
    Pflugers Archiv : European journal of physiology, 1992, Volume: 421, Issue:4

    Topics: Animals; Blood Pressure; Capillaries; Ligation; Microcirculation; Muscles; Pentoxifylline; Perfusion; Rats; Rats, Sprague-Dawley; Regional Blood Flow

1992
Effects of torbafylline on muscle atrophy: prevention and recovery.
    Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:6

    Topics: Animals; Female; Hindlimb; Immobilization; Mitochondria, Muscle; Muscle Contraction; Muscles; Muscular Atrophy; Myofibrils; Organ Size; Pentoxifylline; Rats; Rats, Wistar

1992
The effect of torbafylline on enzyme activities in fast and slow muscles with limited blood supply.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1991, Volume: 99, Issue:1-2

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Animals; Citrate (si)-Synthase; Iliac Artery; Ischemia; L-Lactate Dehydrogenase; Ligation; Male; Muscles; Pentoxifylline; Rats; Rats, Inbred Strains

1991
The effect of pentoxifylline (Trental) and two analogues, BL 194 and HWA 448, on the release of plasminogen activators and von Willebrand factor in rats.
    Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bradykinin; Endotoxins; Enzyme-Linked Immunosorbent Assay; Fibrinolysis; Hindlimb; In Vitro Techniques; Male; Pentoxifylline; Rats; Rats, Inbred Strains; Regional Blood Flow; Tissue Plasminogen Activator; von Willebrand Factor

1991
Attenuation of spontaneous pseudopod formation in human neutrophils by pentoxifylline.
    Cell biophysics, 1991, Volume: 18, Issue:3

    Topics: Actins; Adult; Complement C5a; Cytoplasm; Dose-Response Relationship, Drug; Endotoxins; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Pseudopodia; Receptors, Purinergic; Theophylline; Time Factors

1991
Attenuation of antigen-induced bronchoconstriction in guinea pigs by a new xanthine derivative (HWA448).
    International archives of allergy and applied immunology, 1991, Volume: 96, Issue:3

    Topics: Aminophylline; Animals; Antigens; Bronchial Provocation Tests; Bronchoconstriction; Bronchodilator Agents; Guinea Pigs; Histamine; In Vitro Techniques; Muscle Contraction; Pentoxifylline; Serum Albumin, Bovine; Trachea

1991
Influence of pentoxifylline and related analogues in endotoxemic renal failure.
    Circulatory shock, 1991, Volume: 34, Issue:3

    Topics: Acute Kidney Injury; Animals; Dose-Response Relationship, Drug; Endotoxins; Escherichia coli; Kidney; Male; Pentoxifylline; Rats; Rats, Inbred Strains

1991
Attenuation of amphotericin-B nephrotoxicity in the candidiasis rat model.
    Nephron, 1991, Volume: 59, Issue:1

    Topics: Amphotericin B; Animals; Candidiasis; Dose-Response Relationship, Drug; Kidney; Male; Pentoxifylline; Rats; Rats, Inbred Strains

1991
Skeletal muscle microcirculation: the effects of limited blood supply and treatment with torbafylline.
    International journal of microcirculation, clinical and experimental, 1990, Volume: 9, Issue:4

    Topics: Animals; Arterioles; Capillaries; Glycolysis; Iliac Artery; Ischemia; Ligation; Male; Microcirculation; Muscle Contraction; Muscles; Oxygen; Pentoxifylline; Rats; Rats, Inbred Strains; Regional Blood Flow; Vasodilation

1990
Effects of torbafylline, pentoxifylline and buflomedil on vascularisation and fibre type of rat skeletal muscles subjected to limited blood supply.
    British journal of pharmacology, 1990, Volume: 99, Issue:4

    Topics: Animals; Blood Pressure; Body Weight; Capillaries; In Vitro Techniques; Male; Muscle Contraction; Muscles; Nerve Fibers; Organ Size; Pentoxifylline; Pyrrolidines; Rats; Rats, Inbred Strains; Regional Blood Flow; Theobromine

1990
Collateral circulation in skeletal muscles: effect of pentoxifylline and torbafylline.
    Journal of medicine, 1990, Volume: 21, Issue:3-4

    Topics: Animals; Collateral Circulation; Iliac Artery; Ligation; Muscles; Organ Size; Pentoxifylline; Rats; Rats, Inbred Strains; Theobromine

1990
The influence of pentoxifylline and torbafylline on muscle blood flow in animals with peripheral arterial insufficiency.
    Journal of clinical pharmacology, 1990, Volume: 30, Issue:8

    Topics: Animals; Drug Evaluation, Preclinical; Hindlimb; Ischemia; Male; Pentoxifylline; Physical Exertion; Random Allocation; Rats; Rats, Inbred Strains; Regional Blood Flow; Theobromine

1990
Pentoxifylline increases survival of mice in endotoxic shock.
    Progress in clinical and biological research, 1989, Volume: 301

    Topics: Animals; Epoprostenol; Female; Indomethacin; Leukopenia; Lipopolysaccharides; Mice; Pentoxifylline; Prostaglandins, Synthetic; Shock, Septic; Theobromine

1989
The role of prostacyclin in the protective effects of pentoxifylline and other xanthine derivatives in endotoxin action in mice.
    Eicosanoids, 1989, Volume: 2, Issue:3

    Topics: Animals; Endotoxins; Epoprostenol; Female; Indomethacin; Leukopenia; Lipopolysaccharides; Mice; Pentoxifylline; Theobromine; Tumor Necrosis Factor-alpha

1989
The effects of torbafylline on blood flow, pO2 and function of rat ischaemic skeletal muscle.
    European journal of pharmacology, 1989, Jul-04, Volume: 166, Issue:1

    Topics: Acute Disease; Animals; Blood Pressure; Erythrocytes; Hindlimb; Ischemia; Lactates; Male; Microspheres; Muscles; Oxygen Consumption; Pentoxifylline; Physical Conditioning, Animal; Psychomotor Performance; Rats; Rats, Inbred Strains; Regional Blood Flow; Rheology; Theobromine; Time Factors; Vasodilator Agents

1989
Modification of cisplatin-induced renal p-aminohippurate uptake alteration and lipid peroxidation by thiols, Ginkgo biloba extract, deferoxamine and torbafylline.
    Nephron, 1995, Volume: 70, Issue:4

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Cisplatin; Deferoxamine; Glutathione; In Vitro Techniques; Kidney Cortex; Lipid Peroxidation; Male; p-Aminohippuric Acid; Pentoxifylline; Plant Extracts; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds

1995
Influence of pentoxifylline and its derivatives on antibiotic uptake and superoxide generation by human phagocytic cells.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:7

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Cells, Cultured; Clindamycin; Drug Interactions; Erythromycin; Humans; Macrolides; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Phagocytosis; Respiratory Burst; Roxithromycin; Superoxides

1995
HWA-448 reduces gentamicin toxicity in LLC-PK1 cells.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:1

    Topics: Animals; Drug Interactions; Gentamicins; LLC-PK1 Cells; Models, Biological; Pentoxifylline; Sodium-Potassium-Exchanging ATPase; Swine

1995
Effect of torbafylline on muscle blood flow, performance, and capillary supply in ischemic muscles subjected to varying levels of activity.
    Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:7

    Topics: Animals; Body Weight; Capillaries; Electric Stimulation; Electrodes, Implanted; Ischemia; Isometric Contraction; Male; Muscle Contraction; Muscle Fatigue; Muscle, Skeletal; Organ Size; Pentoxifylline; Rats; Rats, Sprague-Dawley; Regional Blood Flow

1994
Phosphodiesterase inhibitory profile of some related xanthine derivatives pharmacologically active on the peripheral microcirculation.
    Biochemical pharmacology, 1994, Mar-02, Volume: 47, Issue:5

    Topics: Animals; Heart Ventricles; Isoenzymes; Male; Microcirculation; Pentoxifylline; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats; Rats, Sprague-Dawley; Xanthines

1994
Effect of torbafylline on mitochondrial calmitine in mouse skeletal muscle regeneration after injection of a myotoxic drug.
    Journal of the neurological sciences, 1993, Volume: 118, Issue:1

    Topics: Animals; Calcium-Binding Proteins; Calsequestrin; Chlorpromazine; Electrophoresis, Polyacrylamide Gel; Immunohistochemistry; Male; Mice; Mitochondria, Muscle; Muscle Proteins; Muscles; Pentoxifylline; Regeneration

1993
Xanthine derivatives: comparison between suppression of tumour necrosis factor-alpha production and inhibition of cAMP phosphodiesterase activity.
    Immunology, 1993, Volume: 78, Issue:4

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Pentoxifylline; Theophylline; Tumor Necrosis Factor-alpha; Xanthines

1993
Fine structure of capillaries in ischaemic and non ischaemic rat striated muscle. Effect of torbafylline.
    International journal of microcirculation, clinical and experimental, 1993, Volume: 12, Issue:1

    Topics: Animals; Capillaries; Electric Stimulation; Ischemia; Male; Muscles; Pentoxifylline; Rats; Rats, Sprague-Dawley; Reference Values

1993
Correlation of function and energy metabolism in rat ischemic skeletal muscle by 31P-NMR spectroscopy: effects of torbafylline.
    Journal of medicine, 1993, Volume: 24, Issue:1

    Topics: Animals; Disease Models, Animal; Electric Stimulation; Hydrogen-Ion Concentration; Ischemia; Magnetic Resonance Spectroscopy; Male; Muscle Contraction; Muscles; Pentoxifylline; Phosphates; Phosphocreatine; Rats; Rats, Wistar

1993
Inhibition of LPS and Plasmodium falciparum induced cytokine secretion by pentoxifylline and two analogues.
    Scandinavian journal of immunology, 1997, Volume: 45, Issue:5

    Topics: Adult; Animals; Cytokines; Female; Humans; In Vitro Techniques; Interleukin-1; Interleukin-6; Leukocytes, Mononuclear; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Pentoxifylline; Phosphodiesterase Inhibitors; Plasmodium falciparum; Tumor Necrosis Factor-alpha

1997
Role of neutrophils and macrophages in experimental nephrosis of the rat.
    Renal failure, 1998, Volume: 20, Issue:1

    Topics: Animals; Kidney; Kidney Function Tests; Macrophages; Male; Nephrotic Syndrome; Neutrophils; Pentoxifylline; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley

1998
Regional perfusion and oxygenation of tumors upon methylxanthine derivative administration.
    International journal of radiation oncology, biology, physics, 1998, Nov-01, Volume: 42, Issue:4

    Topics: Animals; Male; Neoplasms, Experimental; Oxygen Consumption; Pentoxifylline; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sarcoma, Experimental; Vasodilator Agents

1998
Torbafylline (HWA 448) inhibits enhanced skeletal muscle ubiquitin-proteasome-dependent proteolysis in cancer and septic rats.
    The Biochemical journal, 2002, Jan-15, Volume: 361, Issue:Pt 2

    Topics: Animals; Cysteine Endopeptidases; Down-Regulation; Hydrolysis; Male; Multienzyme Complexes; Muscle, Skeletal; Pentoxifylline; Proteasome Endopeptidase Complex; Rats; Rats, Wistar; RNA, Messenger; Sarcoma, Yoshida; Sepsis; Tumor Necrosis Factor-alpha; Ubiquitin

2002
Anti-TNF treatment reduces rat skeletal muscle wasting in monocrotaline-induced cardiac cachexia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2008, Volume: 105, Issue:6

    Topics: Animals; Anorexia; Blotting, Western; Body Weight; Cachexia; Eating; Enzyme-Linked Immunosorbent Assay; Gene Expression; Heart Diseases; Male; Monocrotaline; Muscle, Skeletal; Organ Size; Pentoxifylline; Poisons; Rats; Rats, Sprague-Dawley; Receptors, Tumor Necrosis Factor, Type I; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Tumor Necrosis Factor Inhibitors; Ubiquitin; Weight Loss

2008
Phosphodiesterase (PDE) inhibitor torbafylline (HWA 448) attenuates burn-induced rat skeletal muscle proteolysis through the PDE4/cAMP/EPAC/PI3K/Akt pathway.
    Molecular and cellular endocrinology, 2014, Aug-05, Volume: 393, Issue:1-2

    Topics: Animals; Burns; Cyclic Nucleotide Phosphodiesterases, Type 4; Male; Models, Biological; Muscle, Skeletal; Pentoxifylline; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Proteolysis; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction

2014