topotecan has been researched along with tamoxifen in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (53.85) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Cho, H; Elkamhawy, A; Heo, JC; Kim, HY; Kim, KH; Lee, CO; Nam, DH; Pae, AN; Park, WK; Roh, EJ; Seol, HJ; Viswanath, AN; Yang, H | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Lichtman, SM; Skirvin, JA | 1 |
| Hensley, ML | 1 |
| Kim, R; Kocarek, TA; Lan, L; Schuetz, E; Schuetz, J; Strom, S; Yasuda, K | 1 |
| Imai, Y; Sugimoto, Y; Tsukahara, S; Tsuruo, T; Ueda, K | 1 |
| Asada, S; Imai, Y; Ishikawa, E; Sugimoto, Y | 1 |
| Hollingshead, MG | 1 |
| Al-Kadhimi, Z; Chow, W; Doroshow, JH; Frankel, P; Leong, L; Lim, D; Mamelak, A; Margolin, K; Morgan, RJ; Shibata, S; Somlo, G; Synold, T; Twardowski, P; Yen, Y | 1 |
| Iqbal, Z; Khuroo, T; Padhi, S; Panda, AK; Talegaonkar, S; Verma, D | 1 |
3 review(s) available for topotecan and tamoxifen
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Pharmacokinetic considerations of oral chemotherapy in elderly patients with cancer.
Topics: Administration, Oral; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Complementary Therapies; Cytochrome P-450 Enzyme System; Dacarbazine; Etoposide; Humans; Idarubicin; Neoplasms; Tamoxifen; Temozolomide; Thalidomide; Topotecan | 2002 |
Epithelial ovarian cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Combined Modality Therapy; Deoxycytidine; Docetaxel; Doxorubicin; Etoposide; Female; Gemcitabine; Humans; Ifosfamide; Neoplasm Recurrence, Local; Ovarian Neoplasms; Paclitaxel; Platinum Compounds; Practice Guidelines as Topic; Tamoxifen; Taxoids; Topotecan; Vinblastine; Vinorelbine | 2002 |
1 trial(s) available for topotecan and tamoxifen
| Article | Year |
|---|---|
Plasma and cerebrospinal fluid pharmacokinetics of topotecan in a phase I trial of topotecan, tamoxifen, and carboplatin, in the treatment of recurrent or refractory brain or spinal cord tumors.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Dose-Response Relationship, Drug; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Spinal Cord Neoplasms; Tamoxifen; Topotecan; Young Adult | 2010 |
9 other study(ies) available for topotecan and tamoxifen
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Discovery of potent and selective cytotoxic activity of new quinazoline-ureas against TMZ-resistant glioblastoma multiforme (GBM).
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Dose-Response Relationship, Drug; Drug Discovery; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Models, Molecular; Molecular Conformation; Quinazolines; Structure-Activity Relationship; Temozolomide; Urea | 2015 |
Development of a real-time in vivo transcription assay: application reveals pregnane X receptor-mediated induction of CYP3A4 by cancer chemotherapeutic agents.
Topics: Animals; Antineoplastic Agents; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Etoposide; Genes, Reporter; Humans; Male; Mice; Mice, Inbred C57BL; Mixed Function Oxygenases; Pregnane X Receptor; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger; Tamoxifen; Topotecan; Transcription, Genetic | 2002 |
Reversal of breast cancer resistance protein-mediated drug resistance by estrogen antagonists and agonists.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Breast Neoplasms; Cell Survival; Diethylstilbestrol; Drug Resistance, Neoplasm; Estrogen Antagonists; Estrogens; Estrone; Female; Humans; K562 Cells; Kinetics; Mitoxantrone; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Tamoxifen; Topotecan; Tumor Cells, Cultured | 2003 |
Estrogen-mediated post transcriptional down-regulation of breast cancer resistance protein/ABCG2.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blotting, Northern; Breast Neoplasms; Cell Line, Tumor; Down-Regulation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor alpha; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Tamoxifen; Topotecan; Transduction, Genetic | 2005 |
Antitumor efficacy testing in rodents.
Topics: Animals; Antineoplastic Agents; Biological Availability; Dacarbazine; Data Interpretation, Statistical; Drug Approval; Drug Design; Drug Screening Assays, Antitumor; Drugs, Investigational; Endpoint Determination; Humans; Kaplan-Meier Estimate; Mice; Neoplasms; Pharmaceutical Vehicles; Random Allocation; Rats; Research Design; Rodentia; Sample Size; Tamoxifen; Temozolomide; Topotecan; Transplantation, Heterologous; United States | 2008 |
Topotecan-tamoxifen duple PLGA polymeric nanoparticles: investigation of in vitro, in vivo and cellular uptake potential.
Topics: Animals; Antineoplastic Agents, Hormonal; Biological Transport; Drug Carriers; Female; Humans; Intestinal Absorption; Lactic Acid; MCF-7 Cells; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Wistar; Tamoxifen; Topoisomerase I Inhibitors; Topotecan | 2014 |