Page last updated: 2024-08-24

topotecan and st 1481

topotecan has been researched along with st 1481 in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (92.31)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beretta, G; Biasotti, B; Carenini, N; Carminati, P; Dallavalle, S; De Cesare, M; Ferrari, A; Gallo, G; Martinelli, R; Marzi, M; Merlini, L; Penco, S; Perego, P; Pisano, C; Pratesi, G; Tinti, MO; Zunino, F1
Battistuzzi, G; Beretta, GL; Cabri, W; De Cesare, M; Giannini, G; Marastoni, E; Marzi, M; Pisano, C; Vesci, L; Zunino, F1
Beretta, GL; Dallavalle, S; Merlini, L; Morini, G; Musso, L; Penco, S; Rocchetta, DG; Tinelli, S; Zunino, F1
Beggiolin, G; Carenini, N; Carminati, P; De Cesare, M; De Isabella, P; Palumbo, M; Perego, P; Pezzoni, G; Pisano, C; Pratesi, G; Scheffer, GL; Tartaglia, L; Zunino, F1
Carenini, N; Carminati, P; Cucco, C; De Cesare, M; Merlini, L; Penco, S; Perego, P; Pisano, C; Pratesi, G; Righetti, SC; Vesci, L; Zunino, F1
Bucci, F; Carenini, N; Carminati, P; De Cesare, M; Gatti, L; Martinelli, R; Perego, P; Pisano, C; Pratesi, G; Supino, R; Zanier, R; Zuco, V; Zunino, F1
Bottiroli, G; Croce, AC; Favini, E; Supino, R; Zuco, V; Zunino, F1
Beretta, GL; Brigliadori, G; Corna, E; De Cesare, M; Fabbri, F; Ricotti, L; Rosetti, M; Supino, R; Tesei, A; Ulivi, P; Zoli, W; Zunino, F1
Barone, G; Carminati, P; D'Incalci, M; Di Francesco, AM; Frapolli, R; Meco, D; Pisano, C; Riccardi, A; Riccardi, AS; Riccardi, R; Rutella, S; Zucchetti, M1
Carenini, N; Ciusani, E; Corna, E; Gatti, L; Perego, P; Zunino, F1
Gounder, MK; Kulkarni, D; Nazar, AS; Pungaliya, P; Rubin, EH; Saleem, A; Versace, R1
Balsari, A; Carenini, N; De Cesare, M; Perego, P; Petrangolini, G; Pratesi, G; Tortoreto, M; Zunino, F1
Beijnen, JH; Iusuf, D; Lin, F; Marchetti, S; Mazzanti, R; Pluim, D; Schellens, JH; van Tellingen, O1

Other Studies

13 other study(ies) available for topotecan and st 1481

ArticleYear
Novel 7-oxyiminomethyl derivatives of camptothecin with potent in vitro and in vivo antitumor activity.
    Journal of medicinal chemistry, 2001, Sep-27, Volume: 44, Issue:20

    Topics: Animals; Antineoplastic Agents; Camptothecin; DNA; DNA Topoisomerases, Type I; Drug Screening Assays, Antitumor; Humans; Imines; Immunoblotting; Inhibitory Concentration 50; Mice; Mice, Nude; Quantitative Structure-Activity Relationship; Transplantation, Heterologous; Tumor Cells, Cultured

2001
E-ring-modified 7-oxyiminomethyl camptothecins: Synthesis and preliminary in vitro and in vivo biological evaluation.
    Bioorganic & medicinal chemistry letters, 2008, May-01, Volume: 18, Issue:9

    Topics: Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type I; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Stereoisomerism; Structure-Activity Relationship; Xenograft Model Antitumor Assays

2008
Synthesis and cytotoxic activity of new 9-substituted camptothecins.
    Bioorganic & medicinal chemistry letters, 2008, May-01, Volume: 18, Issue:9

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Survival; DNA Topoisomerases, Type I; Drug Screening Assays, Antitumor; Humans; Structure-Activity Relationship; Tumor Cells, Cultured

2008
A novel 7-modified camptothecin analog overcomes breast cancer resistance protein-associated resistance in a mitoxantrone-selected colon carcinoma cell line.
    Cancer research, 2001, Aug-15, Volume: 61, Issue:16

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Camptothecin; DNA Damage; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Gene Expression; HT29 Cells; Humans; Mice; Mice, Nude; Mitoxantrone; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Topotecan; Xenograft Model Antitumor Assays

2001
Pattern of antitumor activity of a novel camptothecin, ST1481, in a large panel of human tumor xenografts.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:12

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Cycle; Cell Division; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Humans; Mice; Mice, Nude; Neoplasms, Experimental; Topoisomerase I Inhibitors; Topotecan; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2002
Cellular bases of the antitumor activity of a 7-substituted camptothecin in hormone-refractory human prostate carcinoma models.
    Biochemical pharmacology, 2003, Apr-15, Volume: 65, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Cell Cycle; Cell Division; DNA Damage; DNA, Neoplasm; Humans; Male; Prostatic Neoplasms; Topotecan; Tumor Cells, Cultured

2003
Subcellular localization of the camptothecin analogues, topotecan and gimatecan.
    Biochemical pharmacology, 2004, Mar-15, Volume: 67, Issue:6

    Topics: Antineoplastic Agents; Camptothecin; DNA Damage; HT29 Cells; Humans; Spectrometry, Fluorescence; Subcellular Fractions; Topotecan; Tumor Cells, Cultured

2004
Cellular basis of antiproliferative and antitumor activity of the novel camptothecin derivative, gimatecan, in bladder carcinoma models.
    Neoplasia (New York, N.Y.), 2005, Volume: 7, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Camptothecin; Disease Models, Animal; DNA Topoisomerases, Type I; Down-Regulation; Female; Humans; Mice; Mice, Nude; Protease Inhibitors; Pyrazines; RNA, Messenger; S Phase; Topoisomerase I Inhibitors; Topotecan; Transplantation, Heterologous; Tumor Cells, Cultured; Urinary Bladder Neoplasms

2005
The novel lipophilic camptothecin analogue gimatecan is very active in vitro in human neuroblastoma: a comparative study with SN38 and topotecan.
    Biochemical pharmacology, 2005, Oct-15, Volume: 70, Issue:8

    Topics: Antineoplastic Agents; Camptothecin; Caspase 3; Caspases; Cell Cycle; Cell Line, Tumor; Comet Assay; Humans; In Situ Nick-End Labeling; In Vitro Techniques; Irinotecan; Neuroblastoma; Topotecan

2005
Sensitization to gimatecan-induced apoptosis by tumor necrosis factor-related apoptosis inducing ligand in prostate carcinoma cells.
    Biochemical pharmacology, 2006, Mar-14, Volume: 71, Issue:6

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Camptothecin; Caspase 8; Caspases; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Combinations; Drug Screening Assays, Antitumor; Drug Synergism; Gene Silencing; Genetic Vectors; Humans; Male; Membrane Glycoproteins; Prostatic Neoplasms; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; RNA, Small Interfering; TNF-Related Apoptosis-Inducing Ligand; Topotecan; Transfection; Tumor Necrosis Factor-alpha; Up-Regulation

2006
Effects of drug efflux proteins and topoisomerase I mutations on the camptothecin analogue gimatecan.
    Investigational new drugs, 2008, Volume: 26, Issue:3

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type I; Dogs; Drug Resistance, Neoplasm; Gene Expression; Humans; Irinotecan; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Mutation; Topotecan; Transfection

2008
Combination of metronomic gimatecan and CpG-oligodeoxynucleotides against an orthotopic pancreatic cancer xenograft.
    Cancer biology & therapy, 2008, Volume: 7, Issue:4

    Topics: Adjuvants, Immunologic; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Cell Line, Tumor; Female; Humans; Mice; Mice, Nude; Oligodeoxyribonucleotides; Pancreatic Neoplasms; Receptors, TNF-Related Apoptosis-Inducing Ligand; TNF-Related Apoptosis-Inducing Ligand; Topotecan; Xenograft Model Antitumor Assays

2008
Abcc4 together with abcb1 and abcg2 form a robust cooperative drug efflux system that restricts the brain entry of camptothecin analogues.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Apr-15, Volume: 19, Issue:8

    Topics: Acridines; Administration, Intravenous; Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Brain; Camptothecin; Chromatography, High Pressure Liquid; Irinotecan; Mice; Mice, Knockout; Multidrug Resistance-Associated Proteins; Tetrahydroisoquinolines; Topotecan

2013