Compounds > topotecan
Page last updated: 2024-08-24

topotecan and rucaparib

topotecan has been researched along with rucaparib in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Batey, MA; Calabrese, CR; Canan, S; Curtin, NJ; Hostomsky, Z; Kyle, S; Maegley, KA; Newell, DR; Skalitzky, D; Thomas, HD; Wang, LZ; Webber, SE1
Boddy, AV; Castelbuono, DJ; Clifford, SC; Curtin, NJ; Daniel, RA; Drew, Y; Hostomsky, Z; Mulligan, EA; Plummer, ER; Rozanska, AL; Thomas, HD; Tweddle, DA1
Anderson, L; Chalukya, M; Dandekar, S; Dering, J; Ginther, C; Ihnen, M; Jänicke, F; Jones, S; Kolarova, T; Konecny, GE; Los, G; Manivong, K; Meuter, A; Qi, JW; Rong, HM; Slamon, DJ; Udar, N; Velculescu, VE; Venkatesan, N; Winterhoff, B; zu Eulenburg, C1

Other Studies

4 other study(ies) available for topotecan and rucaparib

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial.
    Molecular cancer therapeutics, 2007, Volume: 6, Issue:3

    Topics: Animals; Antineoplastic Agents; Benzodiazepines; Cell Line, Tumor; Colorectal Neoplasms; Dacarbazine; DNA Repair; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Gamma Rays; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 3-Ring; Humans; Maximum Tolerated Dose; Mice; Mice, Nude; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Structure-Activity Relationship; Temozolomide; Topoisomerase I Inhibitors; Topotecan

2007
Inhibition of poly(ADP-ribose) polymerase-1 enhances temozolomide and topotecan activity against childhood neuroblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Feb-15, Volume: 15, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Drug Synergism; Enzyme Inhibitors; Humans; Indoles; Mice; Neuroblastoma; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Temozolomide; Topotecan; Xenograft Model Antitumor Assays

2009
Therapeutic potential of the poly(ADP-ribose) polymerase inhibitor rucaparib for the treatment of sporadic human ovarian cancer.
    Molecular cancer therapeutics, 2013, Volume: 12, Issue:6

    Topics: Apoptosis; BRCA2 Protein; Cell Line, Tumor; DNA Fragmentation; Drug Synergism; Female; Histones; Humans; Indoles; Mutation; Ovarian Neoplasms; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Topotecan; Ubiquitin-Protein Ligases

2013