Page last updated: 2024-08-24

topotecan and n-desmethyltopotecan

topotecan has been researched along with n-desmethyltopotecan in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beijnen, JH; Herben, VM; Hop, E; Kettenes-van den Bosch, JJ; Rosing, H; ten Bokkel Huinink, WW; van Gortel-van Zomeren, DM1
Beijnen, JH; Gajjar, AJ; Heideman, RL; Houghton, PJ; Rosing, H; Stewart, CF; Zamboni, WC1
Beijnen, JH; Bult, A; Doyle, E; Rosing, H; van Zomeren, DM1
Beijnen, JH; Bult, A; Doyle, E; Rosing, H; Schellens, JH; ten Bokkel, WW; van Zomeren, DM1
Bai, F; Hanna, SK; Iacono, LC; Johnston, B; Kirstein, MN; Stewart, CF1

Other Studies

5 other study(ies) available for topotecan and n-desmethyltopotecan

ArticleYear
Isolation and structural confirmation of N-desmethyl topotecan, a metabolite of topotecan.
    Cancer chemotherapy and pharmacology, 1997, Volume: 39, Issue:6

    Topics: Antineoplastic Agents; Camptothecin; Chromatography, High Pressure Liquid; Humans; Mass Spectrometry; Spectrometry, Fluorescence; Topotecan

1997
Phenytoin alters the disposition of topotecan and N-desmethyl topotecan in a patient with medulloblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:3

    Topics: Anticonvulsants; Antineoplastic Agents; Cerebellar Neoplasms; Child, Preschool; Drug Interactions; Humans; Lactones; Male; Medulloblastoma; Metabolic Clearance Rate; Models, Biological; Phenytoin; Topotecan

1998
O-glucuronidation, a newly identified metabolic pathway for topotecan and N-desmethyl topotecan.
    Anti-cancer drugs, 1998, Volume: 9, Issue:7

    Topics: Antineoplastic Agents; Female; Glucuronates; Humans; Ovarian Neoplasms; Topotecan

1998
Quantification of topotecan and its metabolite N-desmethyltopotecan in human plasma, urine and faeces by high-performance liquid chromatographic methods.
    Journal of chromatography. B, Biomedical sciences and applications, 1999, Apr-30, Volume: 727, Issue:1-2

    Topics: Antineoplastic Agents; Calibration; Chromatography, High Pressure Liquid; Feces; Humans; Neoplasms; Reproducibility of Results; Spectrometry, Fluorescence; Topotecan

1999
Determination of plasma topotecan and its metabolite N-desmethyl topotecan as both lactone and total form by reversed-phase liquid chromatography with fluorescence detection.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003, Feb-05, Volume: 784, Issue:2

    Topics: Antineoplastic Agents; Calibration; Chromatography, High Pressure Liquid; Reproducibility of Results; Spectrometry, Fluorescence; Topotecan

2003