topotecan has been researched along with melphalan in 90 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (4.44) | 18.2507 |
2000's | 13 (14.44) | 29.6817 |
2010's | 61 (67.78) | 24.3611 |
2020's | 12 (13.33) | 2.80 |
Authors | Studies |
---|---|
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Berger, NA; Chatterjee, S; Cheng, MF | 1 |
Ali-Osman, F; Bigner, DD; Colvin, OM; Dolan, ME; Friedman, HS; Griffith, OW; Kaufmann, SH; Moschel, RC; Schold, SC | 1 |
Bissery, MC; Cheshire, PJ; Hallman, JC; Houghton, JA; Houghton, PJ; Mathieu-Boué, A | 1 |
Caserini, C; Orlandi, L; Silvestrini, R; Supino, R; Vaglini, M; Zaffaroni, N; Zunino, F | 1 |
Aleman, AS; Bast, RC; Bevers, MW; Bodurka-Bevers, D; Burke, TW; Champlin, RE; Donato, ML; Freedman, RS; Gajewski, JL; Gershenson, DM; Ippoliti, CM; Levenback, CF; Wharton, JT; Wolf, JK | 1 |
Anderson, JR; Barr, FG; Crist, WM; Donaldson, SS; Maurer, HM; Pappo, AS; Qualman, SJ; Raney, RB; Wiener, ES | 1 |
Aleman, A; Alexanian, R; Anagnostopoulos, A; Champlin, RE; de Lima, M; Donato, ML; Giralt, S; Ippoliti, CM; Weber, D | 1 |
Díaz, MA; González-Vicent, M; Lassaletta, A; Madero, L; Pérez-Martínez, A; Sevilla, J | 1 |
Cheung, IY; Cheung, NK; Kramer, K; Kushner, BH; Modak, S | 1 |
Al Harbi, T; Al-Faris, N; Doyle, J; Gassas, A; Goia, C; Pappo, A | 1 |
Cheng, S; Evans, WK; Shepherd, FA; Stys-Norman, D | 1 |
Barnhart, JR; Grigoryan, RS; Keshelava, N; Reynolds, CP; Yang, B | 1 |
Aleman, A; Anderson, KO; Brown, J; Campagnaro, E; Cleeland, C; Giralt, S; Mendoza, F; Roden, L; Saliba, R; Weber, D | 1 |
García-Sanz, R; González-López, TJ; Graciani, IF; Hermida, G; San Miguel, JF; Vázquez, L | 1 |
Abramson, DH; Brodie, SE; Dunkel, IJ; Gobin, YP; Marr, B | 2 |
Anderlini, P; Champlin, RE; Donato, M; Giralt, SA; Hosing, C; Kazmi, SM; Popat, U; Qazilbash, MH; Qureshi, S; Saliba, RM; Wang, M | 1 |
Athanasopoulos, A; Daladimos, T; Karabelis, A; Kosmas, C; Mylonakis, N; Theotikos, E; Tsakonas, G | 2 |
Castellano, A; De Ioris, MA; De Pasquale, MD; De Vito, R; Donfrancesco, A; Garganese, MC; Ilari, I; Inserra, A; Jenkner, A; Locatelli, F; Natali, G; Ravà, L | 1 |
Kumabe, T; Niizuma, H; Osawa, S; Saito, R; Sonoda, Y; Tominaga, T; Watanabe, M | 1 |
Glimelius, B; Lahn, M | 1 |
Abramson, DH; Brodie, SE; Dunkel, IJ; Gobin, YP; Hung, C; Marr, BP | 1 |
Abramson, DH; Brodie, SE; Dunkel, I; Gobin, YP; Marr, BP; Palioura, S | 1 |
Abramson, DH; Brodie, SE; Dunkel, IJ; Gobin, YP; Marr, BP | 1 |
Ceciliano, A; Chantada, GL; Dominguez, J; Fandino, AC; Millan, N; Schaiquevich, P; Taich, P; Villasante, F | 1 |
Buitrago, E; Ceciliano, A; Chantada, GL; Fandino, A; Lucena, E; Romero, L; Sampor, C; Schaiquevich, P; Taich, P; Villasante, F | 1 |
Abramson, DH; Brodie, SE; Dunkel, IJ; Francis, JH; Gobin, YP; Marr, BP; Riedel, ER | 1 |
Arepalli, SA; Caywood, EH; Jabbour, P; Lally, SE; Manjandavida, FP; Pieretti, G; Shields, CL; Shields, JA | 1 |
Ghadimi, H; Ghassemi, F; Khodabandeh, A; Roohipoor, R; Shields, CL | 1 |
Maidana, DE; Pellegrini, M; Shields, CL; Shields, JA | 1 |
Kamimura, S; Moritake, H; Nunoi, H; Takeshima, H; Yamada, A; Yamashita, S | 1 |
Palanivelu, MS; Ramanjulu, R | 1 |
Ghassemi, F; Khodabande, A; Shields, CL | 1 |
Brennan, R; Kaste, SC; Orr, B; Tse, BC; Wilson, MW | 1 |
Belmar, Á; Ossandón, D; Pérez, V; Shields, CL; Varas, M; Zanolli, M; Zúñiga, P | 1 |
Lawson, BM; Saktanasate, J; Say, EA; Shields, CL | 1 |
Dolz-Marco, R; Ferenczy, SR; Hasanreisoglu, M; Shields, CL; Shields, JA | 1 |
Cao, C; Jabbour, PM; Pointdujour-Lim, R; Say, EA; Shields, CL; Shields, JA | 1 |
Bansal, N; Koundanya, V; Ramamurthy, S; Ravikumar, R; Rishi, P; Saravanan, M; Sharma, T | 1 |
Bertelli, E; Bracco, S; Cioni, S; De Francesco, S; Galluzzi, P; Gennari, P; Guglielmucci, D; Hadjistilianou, T; Leonini, S; Romano, DG; Tarantino, F; Vallone, IM; Venturi, C | 1 |
Bracco, S; De Francesco, S; Galluzzi, P; Hadjistilianou, T; Menicacci, F; Motolese, E | 1 |
Abruzzo, TA; Augsburger, JJ; Corrêa, ZM; Geller, JI; Lane, A; Michaels, ST | 1 |
Beggache, M; Douglass, AM; Say, EA; Shields, CL; Shields, JA | 1 |
Aisenbrey, S; Hagemann, U; Januschowski, K; Schnichels, S; Schrader, M; Süsskind, D | 1 |
Abramson, DH; Brodie, SE; Dunkel, IJ; Fabius, AW; Francis, JH; Gobin, YP; Marr, BP; Mondesire-Crump, I | 1 |
Hasanreisoglu, M; Iyer, PG; Jabbour, P; Lally, SE; Say, EA; Shields, CL; Shields, JA | 1 |
Alset, AE; Caywood, E; Jabbour, P; Say, EA; Shields, CL; Shields, JA | 1 |
Fuller, DG; Jabbour, PM; Khoo, CT; Magan, T; Shields, CL | 1 |
Abramson, DH; Chantada, GL; Fabius, AW; Francis, JH; Schaiquevich, P | 1 |
Abramson, DH; Brodie, SE; Francis, JH; Marr, B; Mondesire-Crump, I; Zabor, EC | 1 |
Abramson, DH; Francis, JH; Iyer, S; Karl, MD; Marr, B | 1 |
Beck-Popovic, M; Fabian, ID; Gaillard, MC; Munier, FL; Puccinelli, F | 1 |
Chan, H; Gallie, BL; Halliday, W; Hèon, E; Shaikh, F; Soliman, SE | 1 |
Aggarwal, V; Dhami, A; Maitray, A; Munusamy, S; Ramamurthy, S; Ravikumar, R; Rishi, P; Sharma, M; Sharma, T | 1 |
Abramson, DH; Brodie, SE; Francis, JH; Gobin, YP; Iyer, S | 1 |
Abramson, DH; Berry, JL; Cassoux, N; Francis, JH; Frenkel, S; Hadjistilianou, D; Ji, X; Munier, FL; Schefler, AC; Shields, CL; Teixeira, LF | 1 |
Beck-Popovic, M; Gaillard, MC; Hadjistilianou, D; Maeder, P; Munier, FL; Puccinelli, F; Stathopoulos, C | 1 |
Bogart, E; Chastagner, P; Cougnenc, O; Defachelles, AS; Ferry, I; Kolesnikov-Gauthier, H; Michon, J; Oudoux, A; Proust, S; Schleiermacher, G; Valteau-Couanet, D | 1 |
Ceciliano, A; Chantada, GL; Fandiño, A; Funes, S; Lagomarsino, E; Manzitti, J; Neira, P; Peralta, L; Sampor, C; Schaiquevich, P; Sgroi, M; Villasante, F | 1 |
Abramson, DH; Brodie, SE; Dunkel, IJ; Francis, JH; Gobin, YP; Levin, A; Mauguen, A; Mondesire-Crump, I; Rowlands, MA | 1 |
Ancona-Lezama, D; Dalvin, LA; Jabbour, P; Lucio-Alvarez, JA; Masoomian, B; Shields, CL | 1 |
Bosaleh, A; Chantada, G; Deu, A; Fandiño, A; Requejo, F; Rodriguez, A; Sampor, C; Schaiquevich, P; Sgroi, M; Zugbi, S | 1 |
Ancona-Lezama, D; Dalvin, LA; Jabbour, P; Lucio-Alvarez, JA; Shields, CL | 1 |
Beck-Popovic, M; Gaillard, MC; Moulin, A; Munier, FL; Puccinelli, F; Stathopoulos, C | 1 |
Guo, L; Han, M; Li, J; Song, D; Wang, C; Wang, L; Wang, Z; Wu, C; Yang, Y; Zhao, J | 1 |
Aroonroch, R; Boontawon, T; Chaitankar, V; Chittavanich, P; Hongeng, S; Jinawath, N; Kaewkhaw, R; Rojanaporn, D; Saengwimol, D; Thammachote, W | 1 |
Abramson, DH; Brodie, S; Francis, JH; Gobin, YP; Levin, AM; McFadden, M | 1 |
Blair, M; Kotlyar, B; Shapiro, M | 1 |
Camp, DA; Lally, SE; Shields, CL | 1 |
Cheon, JE; Choi, JY; Choi, YH; Hong, CR; Hong, KT; Kang, HJ; Kim, IH; Kim, SK; Lee, YJ; Park, JD; Park, KD; Park, SH; Phi, JH; Shin, HY; Wang, KC | 1 |
Jabbour, P; Leahey, AM; Selzer, EB; Shields, CL; Welch, RJ | 1 |
Akyüz, C; Kiratli, H; Koç, I; Öztürk, E; Varan, A | 1 |
Ancona-Lezama, D; Baldassari, MP; Dalvin, LA; Das, S; Hammoud, B; Jabbour, P; Lim, LS; Ramesh, S; Shields, CL; Shivashankar, K; Sweid, A; Texakalidis, P; Tjoumakaris, S; Weinberg, JH; Xu, V | 1 |
Abramson, DH; Brodie, SE; Francis, JH; Muca, E; Nadelmann, J | 1 |
Daniels, AB; Friedman, DL; Froehler, MT; Zheng, Y | 1 |
Borri, M; De Francesco, S; Hadjistilianou, T; Stacey, AW | 1 |
Acosta, G; Fiani, B; Haynes, M; Nikolaidis, D; Rose, A; Runnels, J; Wong, A | 1 |
Abramson, DH; Bogan, CM; Boyd, KL; Bridges, TM; Calcutt, MW; Chen, SC; Daniels, AB; Francis, JH; Friedman, DL; Hsieh, T; Kaczmarek, JV; Liao, A; Lindsley, CW; Nadelmann, JB; Pierce, JM; Richmond, A | 1 |
Kıratlı, H; Koç, İ; Lotfisadigh, S; Taylan Şekeroğlu, H | 1 |
Abramson, DH; Francis, JH; Gobin, YP | 1 |
Abramson, DH; Antal, Z; Dunkel, IJ; Francis, JH; Friedman, DN; Gobin, YP; Marathe, PH | 1 |
Beck, E; Dahmane, N; Garman, T; Hagen, N; Holland, D; Klumpp-Thomas, C; Laramee, M; Martin, B; McKnight, C; Souweidane, M; Thomas, CJ; Wang, A; Wilson, K; Xu, X; Zhang, X | 1 |
Badel, JN; Bogart, E; Corradini, N; Cougnenc, O; Courbon, F; Defachelles, AS; Deley, MCL; Gambart, M; Giraudet, AL; Kolesnikov-Gauthier, H; Oudoux, A; Rault, E; Schleiermacher, G; Sevrin, F; Valteau-Couanet, D | 1 |
7 review(s) available for topotecan and melphalan
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Rhabdomyosarcoma and undifferentiated sarcoma in the first two decades of life: a selective review of intergroup rhabdomyosarcoma study group experience and rationale for Intergroup Rhabdomyosarcoma Study V.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Disease-Free Survival; Doxorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Ifosfamide; Infant; Male; Melphalan; Multicenter Studies as Topic; Neoplasm Recurrence, Local; Neoplasm Staging; Pilot Projects; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Rhabdomyosarcoma; Salvage Therapy; Sarcoma; Soft Tissue Neoplasms; Survival Rate; Topotecan; Treatment Outcome; Vincristine | 2001 |
Chemotherapy for relapsed small cell lung cancer: a systematic review and practice guideline.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials, Phase III as Topic; Etoposide; Female; Humans; Infusions, Intravenous; Lomustine; Lung Neoplasms; Male; Maximum Tolerated Dose; Melphalan; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Ontario; Practice Guidelines as Topic; Prognosis; Randomized Controlled Trials as Topic; Salvage Therapy; Survival Analysis; Topotecan | 2007 |
Double high-dose chemotherapy and stem cell transplantation in adult Wilms' tumor.
Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carboplatin; Cyclophosphamide; Etoposide; Fatal Outcome; Hematopoietic Stem Cell Transplantation; Humans; Ifosfamide; Male; Melphalan; Paclitaxel; Radiography; Salvage Therapy; Topotecan; Transplantation, Autologous; Wilms Tumor; Young Adult | 2010 |
Window-of-opportunity trials to evaluate clinical activity of new molecular entities in oncology.
Topics: Adult; Antineoplastic Agents; Child; Clinical Trials as Topic; Epirubicin; Etoposide; Humans; Melphalan; Molecular Targeted Therapy; Neoplasms; Topotecan | 2011 |
OCULAR PHARMACOLOGY OF CHEMOTHERAPY FOR RETINOBLASTOMA.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Clinical Trials as Topic; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Infusions, Intra-Arterial; Injections, Intraocular; Melphalan; Retinal Neoplasms; Retinoblastoma; Topotecan | 2017 |
The role for intra-arterial chemotherapy for refractory retinoblastoma: a systematic review.
Topics: Antineoplastic Agents; Bronchial Spasm; Carboplatin; Drug Resistance, Neoplasm; Edema; Eyelashes; Febrile Neutropenia; Humans; Infusions, Intra-Arterial; Melphalan; Methotrexate; Nausea; Retinal Neoplasms; Retinoblastoma; Salvage Therapy; Topotecan; Vitreous Hemorrhage; Vomiting | 2021 |
7 trial(s) available for topotecan and melphalan
Article | Year |
---|---|
High-dose topotecan, melphalan, and cyclophosphamide (TMC) with stem cell support: a new regimen for the treatment of advanced ovarian cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Melphalan; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms; Survival Rate; Topotecan | 2001 |
High-dose topotecan, melphalan and cyclophosphamide (TMC) with stem cell support: a new regimen for the treatment of multiple myeloma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Melphalan; Middle Aged; Multiple Myeloma; Pilot Projects; Remission Induction; Survival Rate; Topotecan; Transplantation, Autologous; Treatment Outcome | 2004 |
High-dose chemotherapy with autologous stem cell rescue for children with high risk and recurrent medulloblastoma and supratentorial primitive neuroectodermal tumors.
Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cerebellar Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Male; Medulloblastoma; Melphalan; Neoplasm Recurrence, Local; Neuroectodermal Tumors, Primitive; Peripheral Blood Stem Cell Transplantation; Radiotherapy, Adjuvant; Supratentorial Neoplasms; Thiotepa; Topotecan; Transplantation, Autologous; Treatment Outcome | 2005 |
Superselective ophthalmic artery chemotherapy as primary treatment for retinoblastoma (chemosurgery).
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Electroretinography; Female; Fluorescein Angiography; Follow-Up Studies; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Ophthalmic Artery; Prospective Studies; Retinal Neoplasms; Retinoblastoma; Topotecan; Treatment Outcome; Visual Acuity | 2010 |
Phase II trial of high-dose topotecan, melphalan and CY with autologous stem cell support for multiple myeloma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disease-Free Survival; Female; Graft Survival; Hematopoietic Stem Cell Transplantation; Humans; Male; Melphalan; Middle Aged; Multiple Myeloma; Recurrence; Remission Induction; Topotecan; Transplantation, Autologous; Treatment Outcome | 2011 |
Feasibility of Busulfan Melphalan and Stem Cell Rescue After 131I-MIBG and Topotecan Therapy for Refractory or Relapsed Metastatic Neuroblastoma: The French Experience.
Topics: 3-Iodobenzylguanidine; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool; Female; France; Hematopoietic Stem Cell Transplantation; Humans; Male; Melphalan; Neoplasm Metastasis; Neuroblastoma; Risk Factors; Topotecan | 2018 |
Phase II study of
Topics: 3-Iodobenzylguanidine; Adolescent; Busulfan; Child; Child, Preschool; Chronic Disease; Humans; Melphalan; Neoplasm Recurrence, Local; Neuroblastoma; Topotecan; Young Adult | 2023 |
76 other study(ies) available for topotecan and melphalan
Article | Year |
---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water | 2010 |
Schedule-dependent cytotoxicity of topotecan alone and in combination chemotherapy regimens.
Topics: Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Aphidicolin; Camptothecin; Carmustine; Cell Cycle; Cell Death; Cell Line; Cisplatin; Cricetinae; Cricetulus; DNA Damage; DNA Repair; DNA, Neoplasm; Doxorubicin; Drug Synergism; Etoposide; Fibroblasts; Hydroxyurea; Lung; Melphalan; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topotecan | 1994 |
Elevated DNA polymerase alpha, DNA polymerase beta, and DNA topoisomerase II in a melphalan-resistant rhabdomyosarcoma xenograft that is cross-resistant to nitrosoureas and topotecan.
Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Camptothecin; Carmustine; DNA Polymerase I; DNA Polymerase II; DNA Topoisomerases, Type II; Drug Resistance; Drug Screening Assays, Antitumor; Female; Humans; Male; Melphalan; Mice; Mice, Inbred BALB C; Mice, Nude; Rhabdomyosarcoma; Topotecan; Transferases; Transplantation, Heterologous | 1994 |
Therapeutic efficacy of the topoisomerase I inhibitor 7-ethyl-10-(4-[1-piperidino]-1-piperidino)-carbonyloxy-camptothecin against human tumor xenografts: lack of cross-resistance in vivo in tumors with acquired resistance to the topoisomerase I inhibitor
Topics: Adolescent; Adult; Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Child; Colonic Neoplasms; Drug Administration Schedule; Drug Resistance; Drug Screening Assays, Antitumor; Female; Humans; Irinotecan; Male; Melphalan; Mice; Mice, Inbred CBA; Neoplasm Transplantation; Rhabdomyosarcoma; Topotecan; Transplantation, Heterologous; Tumor Cells, Cultured; Vincristine | 1993 |
Modulation of melphalan cytotoxic activity in human melanoma cell lines.
Topics: Antineoplastic Agents, Alkylating; Blotting, Northern; Camptothecin; Drug Interactions; Enzyme Inhibitors; Ethacrynic Acid; Humans; Melanoma; Melphalan; Temperature; Topoisomerase I Inhibitors; Topotecan; Tumor Cells, Cultured | 1996 |
High-dose cyclophosphamide inhibition of humoral immune response to murine monoclonal antibody 3F8 in neuroblastoma patients: broad implications for immunotherapy.
Topics: Adolescent; Adult; Animals; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antibody Formation; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunoglobulin G; Immunosuppressive Agents; Immunotherapy; Infant; Male; Melphalan; Mice; Neuroblastoma; Retrospective Studies; Thiotepa; Topotecan; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome; Vincristine; Whole-Body Irradiation | 2007 |
Does consolidation with autologous stem cell transplantation improve the outcome of children with metastatic or relapsed Ewing sarcoma?
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Carboplatin; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Epirubicin; Etoposide; Follow-Up Studies; Humans; Ifosfamide; Infection Control; Kaplan-Meier Estimate; Melphalan; Neoplasm Recurrence, Local; Peripheral Blood Stem Cell Transplantation; Postoperative Care; Retrospective Studies; Risk; Salvage Therapy; Sarcoma, Ewing; Topotecan; Transplantation Conditioning; Transplantation, Autologous; Treatment Failure; Vincristine | 2007 |
Flow cytometry analysis of single-strand DNA damage in neuroblastoma cell lines using the F7-26 monoclonal antibody.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Apoptosis; Benzyl Compounds; Cell Line, Tumor; Child; DNA Damage; DNA, Single-Stranded; Enzyme Inhibitors; Fenretinide; Flow Cytometry; Gamma Rays; Humans; Hydrocarbons, Fluorinated; Hydrogen Peroxide; In Situ Nick-End Labeling; Melphalan; Neuroblastoma; Oxidants; Reactive Oxygen Species; Topotecan | 2007 |
Symptom burden after autologous stem cell transplantation for multiple myeloma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Combined Modality Therapy; Female; Hematopoietic Stem Cell Transplantation; Humans; Melphalan; Middle Aged; Multiple Myeloma; Prospective Studies; Remission Induction; Severity of Illness Index; Survival Rate; Thiotepa; Topotecan; Transplantation, Autologous; Tumor Burden | 2008 |
The combination of thalidomide, cyclophosphamide and dexamethasone is potentially useful in highly resistant Hodgkin's lymphoma.
Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dacarbazine; Deoxycytidine; Dexamethasone; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Hodgkin Disease; Humans; Male; Mechlorethamine; Melphalan; Organoplatinum Compounds; Paclitaxel; Peripheral Blood Stem Cell Transplantation; Prednisolone; Prednisone; Procarbazine; Remission Induction; Rituximab; Salvage Therapy; Thalidomide; Topotecan; Transplantation, Autologous; Vidarabine; Vinblastine; Vincristine | 2010 |
Bilateral superselective ophthalmic artery chemotherapy for bilateral retinoblastoma: tandem therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Catheters, Indwelling; Electroretinography; Evoked Potentials, Visual; Female; Follow-Up Studies; Functional Laterality; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Ophthalmic Artery; Retina; Retinal Neoplasms; Retinoblastoma; Topotecan; Treatment Outcome | 2010 |
Second high-dose chemotherapy intensification followed by hematopoietic stem cell transplantation applying a novel high-dose topotecan-based regimen in an adult Wilms' tumor patient: case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chemotherapy, Adjuvant; Cyclophosphamide; Dose-Response Relationship, Drug; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Kidney Neoplasms; Male; Melphalan; Nephrectomy; Topotecan; Wilms Tumor; Young Adult | 2011 |
Short topotecan-based induction regimen in newly diagnosed high-risk neuroblastoma.
Topics: Abdominal Neoplasms; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Etoposide; Female; Humans; Ifosfamide; Infant; Kaplan-Meier Estimate; Lomustine; Male; Melphalan; Mesna; Neuroblastoma; Pilot Projects; Risk Factors; Thoracic Neoplasms; Topotecan; Treatment Outcome | 2011 |
Infratentorial brain metastases of pediatric non-epithelial malignant tumors: three case reports.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Carboplatin; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Dactinomycin; Doxorubicin; Etoposide; Humans; Ifosfamide; Infant; Infratentorial Neoplasms; Irinotecan; Melphalan; Neoplasm Metastasis; Neuroblastoma; Rhabdomyosarcoma; Thiotepa; Topotecan; Vincristine | 2011 |
Success of intra-arterial chemotherapy (chemosurgery) for retinoblastoma: effect of orbitovascular anatomy.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Blood Flow Velocity; Carboplatin; Child; Child, Preschool; Female; Fluorescein Angiography; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Ophthalmic Artery; Orbit; Regional Blood Flow; Retinal Neoplasms; Retinoblastoma; Topotecan; Young Adult | 2012 |
Ophthalmic artery chemosurgery for less advanced intraocular retinoblastoma: five year review.
Topics: Adolescent; Adult; Antineoplastic Agents; Child; Child, Preschool; Disease-Free Survival; Eye; Follow-Up Studies; Humans; Infant; Melphalan; Ophthalmic Artery; Ophthalmologic Surgical Procedures; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan; Young Adult | 2012 |
Three-drug intra-arterial chemotherapy using simultaneous carboplatin, topotecan and melphalan for intraocular retinoblastoma: preliminary results.
Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Infusions, Intra-Arterial; Male; Melphalan; Middle Aged; Pilot Projects; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topoisomerase I Inhibitors; Topotecan; Treatment Outcome; Young Adult | 2012 |
Intra-arterial chemotherapy is more effective than sequential periocular and intravenous chemotherapy as salvage treatment for relapsed retinoblastoma.
Topics: Administration, Intravenous; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; Humans; Injections, Intra-Arterial; Injections, Intraocular; Male; Melphalan; Middle Aged; Neoplasm Recurrence, Local; Ophthalmic Artery; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Salvage Therapy; Topotecan; Treatment Outcome; Vincristine; Young Adult | 2013 |
Clinical pharmacokinetics of intra-arterial melphalan and topotecan combination in patients with retinoblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromatography, High Pressure Liquid; Female; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Ophthalmic Artery; Prospective Studies; Retinal Neoplasms; Retinoblastoma; Topotecan | 2014 |
Electroretinogram monitoring of dose-dependent toxicity after ophthalmic artery chemosurgery in retinoblastoma eyes: six year review.
Topics: Carboplatin; Electroretinography; Humans; Melphalan; Ophthalmic Artery; Retinal Neoplasms; Retinoblastoma; Topotecan; Treatment Outcome | 2014 |
Intra-arterial chemotherapy for retinoblastoma in 70 eyes: outcomes based on the international classification of retinoblastoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Female; Fluorescein Angiography; Follow-Up Studies; Humans; Infant; Infusions, Intra-Arterial; International Classification of Diseases; Male; Melphalan; Microscopy, Acoustic; Ophthalmic Artery; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan; Treatment Outcome; Young Adult | 2014 |
Combined intravitreal melphalan and topotecan for refractory or recurrent vitreous seeding from retinoblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Female; Humans; Infant; Intravitreal Injections; Male; Melphalan; Neoplasm Seeding; Recurrence; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan; Vitreous Body | 2014 |
Choroidal thickness after intraarterial chemotherapy for retinoblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Atrophy; Case-Control Studies; Child; Child, Preschool; Choroid; Female; Fluorescein Angiography; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Organ Size; Retinal Neoplasms; Retinoblastoma; Tomography, Optical Coherence; Topotecan | 2014 |
Proposed strategy for the use of high-dose chemotherapy with stem cell rescue and intrathecal topotecan without whole-brain irradiation for infantile classic medulloblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Female; Humans; Infant; Injections, Spinal; Medulloblastoma; Melphalan; Neoplasm Recurrence, Local; Prognosis; Stem Cell Transplantation; Topotecan; Transplantation, Autologous | 2014 |
Is combination therapy for resistant vitreous seeds really essential?
Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Male; Melphalan; Neoplasm Seeding; Retinal Neoplasms; Topotecan; Vitreous Body | 2015 |
Is combination therapy for resistant vitreous seeds really essential? - reply.
Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Male; Melphalan; Neoplasm Seeding; Retinal Neoplasms; Topotecan; Vitreous Body | 2015 |
Enophthalmos and choroidal atrophy after intraophthalmic artery chemotherapy for retinoblastoma.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Atrophy; Chemotherapy, Cancer, Regional Perfusion; Choroid; Choroid Diseases; Combined Modality Therapy; Diseases in Twins; Enophthalmos; Female; Fluorescein Angiography; Humans; Infant; Laser Coagulation; Magnetic Resonance Imaging; Melphalan; Ophthalmic Artery; Retinal Neoplasms; Retinoblastoma; Scleritis; Topoisomerase I Inhibitors; Topotecan; Twins, Monozygotic | 2015 |
Using cost-effective intra-arterial chemotherapy to treat retinoblastoma in Chile.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chile; Cost-Benefit Analysis; Developing Countries; Drug Costs; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Retinal Neoplasms; Retinoblastoma; Topotecan | 2014 |
Intravitreal chemotherapy provides control for massive vitreous seeding from retinoblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Eye Neoplasms; Female; Humans; Intravitreal Injections; Melphalan; Neoplasm Seeding; Retinal Neoplasms; Retinoblastoma; Topotecan; Vitreous Body | 2014 |
Spectral Domain Optical Coherence Tomography Reveals Hidden Fovea Beneath Extensive Vitreous Seeding From Retinoblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Eye Neoplasms; Female; Fovea Centralis; Humans; Infusions, Intra-Arterial; Intravitreal Injections; Melphalan; Neoplasm Seeding; Retinal Neoplasms; Retinoblastoma; Tomography, Optical Coherence; Topotecan; Vitreous Body | 2015 |
Rescue intra-arterial chemotherapy following retinoblastoma recurrence after initial intra-arterial chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Child, Preschool; Eye Enucleation; Female; Follow-Up Studies; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Neoplasm Recurrence, Local; Retinal Neoplasms; Retinoblastoma; Retinoscopy; Retreatment; Salvage Therapy; Topotecan; Treatment Failure; Treatment Outcome | 2015 |
Intra-arterial chemotherapy for retinoblastoma: First Indian report.
Topics: Antineoplastic Agents; Carboplatin; Child, Preschool; Dose-Response Relationship, Drug; Female; Fluorescein Angiography; Follow-Up Studies; Fundus Oculi; Humans; Incidence; India; Infant; Injections, Intra-Arterial; Male; Melphalan; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Time Factors; Topoisomerase I Inhibitors; Topotecan | 2015 |
Identification of Intraorbital Arteries in Pediatric Age by High Resolution Superselective Angiography.
Topics: Angiography, Digital Subtraction; Antineoplastic Combined Chemotherapy Protocols; Carotid Artery, Internal; Child, Preschool; Humans; Infusions, Intra-Arterial; Melphalan; Ophthalmic Artery; Orbit; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan | 2015 |
Alternated intra-arterial and intravitreal chemotherapy for advanced intraocular retinoblastoma: preliminary successful results without systemic chemotherapy.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Female; Humans; Infant; Injections, Intra-Arterial; Intravitreal Injections; Male; Melphalan; Neoplasm Seeding; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan | 2015 |
Selective Ophthalmic Artery Infusion Chemotherapy for Advanced Intraocular Retinoblastoma: CCHMC Early Experience.
Topics: Adolescent; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Female; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Ophthalmic Artery; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan | 2016 |
INTRAVITREOUS CHEMOTHERAPY FOR ACTIVE VITREOUS SEEDING FROM RETINOBLASTOMA: Outcomes After 192 Consecutive Injections. The 2015 Howard Naquin Lecture.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Eye Neoplasms; Female; Follow-Up Studies; Humans; Infant; Intravitreal Injections; Male; Melphalan; Neoplasm Seeding; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan; Vitreous Body | 2016 |
Toxic effects of melphalan, topotecan and carboplatin on retinal pigment epithelial cells.
Topics: Antineoplastic Agents; Apoptosis; Carboplatin; Caspase 3; Caspase 7; Cell Count; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Melphalan; Microscopy, Phase-Contrast; Retinal Pigment Epithelium; Topoisomerase I Inhibitors; Topotecan | 2016 |
Simultaneous Bilateral Ophthalmic Artery Chemosurgery for Bilateral Retinoblastoma (Tandem Therapy).
Topics: Carboplatin; Child; Child, Preschool; Electroretinography; Female; Humans; Kaplan-Meier Estimate; Male; Melphalan; Ophthalmic Artery; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan | 2016 |
Secondary and tertiary intra-arterial chemotherapy for massive persistent or recurrent subretinal retinoblastoma seeds following previous chemotherapy exposure: long-term tumor control and globe salvage in 30 eyes.
Topics: Antineoplastic Agents; Carboplatin; Child, Preschool; Female; Humans; Infant; Male; Melphalan; Neoplasm Recurrence, Local; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan | 2016 |
Retinoblastoma Control With Primary Intra-arterial Chemotherapy: Outcomes Before and During the Intravitreal Chemotherapy Era.
Topics: Antineoplastic Agents, Alkylating; Child; Child, Preschool; Eye Enucleation; Female; Humans; Infant; Infusions, Intra-Arterial; Intravitreal Injections; Male; Melphalan; Neoplasm Seeding; Ophthalmic Artery; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topoisomerase I Inhibitors; Topotecan | 2016 |
Intra-arterial Chemotherapy for Adult Onset Retinoblastoma in a 32-Year-Old Man.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Combined Modality Therapy; Humans; Infusions, Intra-Arterial; Male; Melphalan; Neoplasm Recurrence, Local; Neoplasm Seeding; Retinal Neoplasms; Retinoblastoma; Topotecan; Ultrasonography; Visual Acuity; Vitreous Body | 2016 |
Efficacy and Toxicity of Intravitreous Chemotherapy for Retinoblastoma: Four-Year Experience.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cohort Studies; Disease-Free Survival; Electroretinography; Female; Humans; Infant; Injections, Intraocular; Intravitreal Injections; Male; Melphalan; Neoplasm Seeding; Ophthalmic Artery; Ophthalmoscopy; Retina; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topoisomerase I Inhibitors; Topotecan; Treatment Outcome; Vitreous Body | 2017 |
Intraocular Pressure Changes Following Intravitreal Melphalan and Topotecan for the Treatment of Retinoblastoma With Vitreous Seeding.
Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Intravitreal Injections; Male; Melphalan; Neoplasm Seeding; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topoisomerase I Inhibitors; Topotecan; Treatment Outcome; Vitreous Body; Young Adult | 2017 |
Diagnosis and management of secondary epipapillary retinoblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carboplatin; Child, Preschool; Cryotherapy; Female; Humans; Hyperthermia, Induced; Infant; Infusions, Intra-Arterial; Male; Melphalan; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Tomography, Optical Coherence; Topotecan | 2017 |
White orbital mass after enucleation for retinoblastoma: The power of illusion.
Topics: Antineoplastic Combined Chemotherapy Protocols; Catgut; Eye Enucleation; Fluorescein Angiography; Foreign-Body Reaction; Granuloma, Foreign-Body; Humans; Infant; Intravitreal Injections; Magnetic Resonance Imaging; Male; Melphalan; Neoplasm Staging; Orbital Diseases; Orbital Implants; Retinal Neoplasms; Retinoblastoma; Suture Techniques; Topotecan | 2017 |
Intra-arterial chemotherapy for retinoblastoma: Two-year results from tertiary eye-care center in India.
Topics: Antineoplastic Agents, Alkylating; Child, Preschool; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Incidence; India; Infant; Injections, Intra-Arterial; Male; Melphalan; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Time Factors; Topoisomerase I Inhibitors; Topotecan; Treatment Outcome; Ultrasonography | 2017 |
Retinoblastoma Vitreous Seed Clouds (Class 3): A Comparison of Treatment with Ophthalmic Artery Chemosurgery with or without Intravitreous and Periocular Chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child, Preschool; Cohort Studies; Disease-Free Survival; Electroretinography; Female; Humans; Infusions, Intra-Arterial; Intravitreal Injections; Kaplan-Meier Estimate; Male; Melphalan; Neoplasm Seeding; Ophthalmic Artery; Retina; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan; Vitreous Body | 2017 |
Risk of Extraocular Extension in Eyes With Retinoblastoma Receiving Intravitreous Chemotherapy.
Topics: Antineoplastic Agents; Child, Preschool; Cryotherapy; Female; Humans; Infant; Intravitreal Injections; Male; Melphalan; Methotrexate; Microscopy, Acoustic; Neoplasm Seeding; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Risk Factors; Topotecan | 2017 |
Successful conservative treatment of massive choroidal relapse in 2 retinoblastoma patients monitored by ultrasound biomicroscopy and/or spectral domain optic coherence tomography.
Topics: Antineoplastic Combined Chemotherapy Protocols; Choroid Neoplasms; Conservative Treatment; Fatal Outcome; Female; Fluorescein Angiography; Humans; Infant; Infusions, Intra-Arterial; Magnetic Resonance Imaging; Melphalan; Microscopy, Acoustic; Neoplasm Recurrence, Local; Retinal Neoplasms; Retinoblastoma; Tomography, Optical Coherence; Topotecan | 2018 |
Feasibility and results of an intraarterial chemotherapy program for the conservative treatment of retinoblastoma in Argentina.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Argentina; Carboplatin; Child; Child, Preschool; Conservative Treatment; Disease-Free Survival; Feasibility Studies; Female; Humans; Infusions, Intra-Arterial; Male; Melphalan; Middle Aged; Neoplasm Recurrence, Local; Ophthalmic Artery; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan; Young Adult | 2018 |
Total retinal detachments due to retinoblastoma: Outcomes following intra-arterial chemotherapy/ophthalmic artery chemosurgery.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child, Preschool; Electroretinography; Female; Follow-Up Studies; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Ophthalmic Artery; Retina; Retinal Detachment; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Survival Analysis; Topotecan; Treatment Outcome | 2018 |
Ophthalmic Vascular Events after Primary Unilateral Intra-arterial Chemotherapy for Retinoblastoma in Early and Recent Eras.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Female; Fluorescein Angiography; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Ophthalmoscopy; Retinal Diseases; Retinal Neoplasms; Retinal Vessels; Retinoblastoma; Retrospective Studies; Risk Factors; Topotecan; Ultrasonography; Young Adult | 2018 |
Combined high-dose intra-arterial and intrathecal chemotherapy for the treatment of a case of extraocular retinoblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Central Nervous System Neoplasms; Child, Preschool; Humans; Infusions, Intra-Arterial; Injections, Spinal; Male; Melphalan; Retinal Neoplasms; Retinoblastoma; Topotecan | 2018 |
OPHTHALMIC VASCULAR EVENTS AFTER INTRA-ARTERIAL CHEMOTHERAPY FOR RETINOBLASTOMA: Real-World Comparison Between Primary and Secondary Treatments.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Choroid; Female; Fluorescein Angiography; Humans; Infant; Infant, Newborn; Infusions, Intra-Arterial; Male; Melphalan; Ophthalmic Artery; Retinal Diseases; Retinal Neoplasms; Retinal Vessels; Retinoblastoma; Retrospective Studies; Topotecan; Young Adult | 2019 |
INTRAVITREAL ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR FOR THE MANAGEMENT OF NEOVASCULARIZATION IN RETINOBLASTOMA AFTER INTRAVENOUS AND/OR INTRAARTERIAL CHEMOTHERAPY: Long-Term Outcomes in a Series of 35 Eyes.
Topics: Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Female; Fluorescein Angiography; Humans; Infant; Infusions, Intra-Arterial; Infusions, Intravenous; Intravitreal Injections; Male; Melphalan; Microscopy, Acoustic; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Retinal Neoplasms; Retinal Neovascularization; Retinoblastoma; Retrospective Studies; Topotecan; Vascular Endothelial Growth Factor A | 2019 |
Intra-arterial chemotherapy for unilateral advanced intraocular retinoblastoma: Results and short-term complications.
Topics: Antineoplastic Agents; Child, Preschool; Eye; Female; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Meningeal Arteries; Ophthalmic Artery; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan; Treatment Outcome | 2018 |
A three-dimensional organoid model recapitulates tumorigenic aspects and drug responses of advanced human retinoblastoma.
Topics: Antineoplastic Agents; Carcinogenesis; Child, Preschool; DNA Copy Number Variations; Gene Expression Regulation, Neoplastic; Humans; Infant; Melphalan; Models, Biological; Neoplasm Staging; Organoids; Retinal Neoplasms; Retinoblastoma; Topotecan | 2018 |
Association of electroretinography with visual outcomes after ophthalmic artery chemosurgery for retinoblastoma in ICRb D and E eyes.
Topics: Carboplatin; Case-Control Studies; Child; Child, Preschool; Electroretinography; Female; Humans; Infant; Infant, Newborn; Male; Melphalan; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan; Visual Acuity | 2019 |
Exudative Retinal Detachment Following Intravitreal Chemotherapeutic Treatment for Retinoblastoma.
Topics: Antineoplastic Agents, Alkylating; Child, Preschool; Drug Therapy, Combination; Fluorescein Angiography; Follow-Up Studies; Fundus Oculi; Humans; Injections, Intraocular; Intravitreal Injections; Macula Lutea; Male; Melphalan; Retinal Detachment; Retinal Neoplasms; Retinoblastoma; Topoisomerase I Inhibitors; Topotecan; Triamcinolone Acetonide; Ultrasonography | 2019 |
Heterochromia following intravitreal chemotherapy in two cases.
Topics: Diagnosis, Differential; Drug Therapy, Combination; Female; Humans; Infant; Intravitreal Injections; Iris Diseases; Melphalan; Pigmentation Disorders; Retinal Neoplasms; Retinoblastoma; Tomography, Optical Coherence; Topotecan | 2019 |
Tandem high-dose chemotherapy with topotecan-thiotepa-carboplatin and melphalan-etoposide-carboplatin regimens for pediatric high-risk brain tumors.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Child; Child, Preschool; Etoposide; Female; Humans; Infant; Male; Melphalan; Retrospective Studies; Stem Cell Transplantation; Survival Rate; Thiotepa; Topotecan; Transplantation, Autologous; Treatment Outcome | 2019 |
Management of retinoblastoma in older children (>5 years) using intra-arterial chemotherapy: Comparison of outcomes to prechemotherapy and intravenous chemotherapy eras.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Carboplatin; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Intravitreal Injections; Male; Melphalan; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topoisomerase I Inhibitors; Topotecan; Treatment Outcome; Young Adult | 2019 |
Comparison of intravitreal melphalan with and without topotecan in the management of vitreous disease in retinoblastoma.
Topics: Antineoplastic Agents, Alkylating; Child, Preschool; Drug Therapy, Combination; Eye Diseases; Eye Enucleation; Female; Follow-Up Studies; Humans; Infant; Intravitreal Injections; Kaplan-Meier Estimate; Male; Melphalan; Neoplasm Seeding; Proportional Hazards Models; Retinal Diseases; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topoisomerase I Inhibitors; Topotecan; Treatment Outcome; Vitreous Body | 2020 |
Intra-Arterial Chemotherapy for Retinoblastoma in Infants ≤10 kg: 74 Treated Eyes with 222 IAC Sessions.
Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan; Treatment Outcome | 2020 |
Is intravitreal topotecan toxic to retinal function?
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Electroretinography; Female; Follow-Up Studies; Humans; Infant; Intravitreal Injections; Male; Melphalan; Retina; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topoisomerase I Inhibitors; Topotecan | 2021 |
Intra-arterial Chemotherapy as Primary Treatment for Cavitary Retinoblastoma: Excellent Response in Eight Tumors.
Topics: Antineoplastic Agents; Carboplatin; Female; Fluorescein Angiography; Follow-Up Studies; Fundus Oculi; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Time Factors; Topoisomerase I Inhibitors; Topotecan; Treatment Outcome; Ultrasonography | 2021 |
The Addition of Topotecan to Melphalan in the Treatment of Retinoblastoma with Intra-arterial Chemotherapy.
Topics: Antineoplastic Agents, Alkylating; Child, Preschool; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluorescein Angiography; Follow-Up Studies; Fundus Oculi; Humans; Infant; Injections, Intra-Arterial; Male; Melphalan; Prospective Studies; Retina; Retinal Neoplasms; Retinoblastoma; Topoisomerase I Inhibitors; Topotecan; Treatment Outcome | 2021 |
Evaluation of intravitreal topotecan dose levels, toxicity and efficacy for retinoblastoma vitreous seeds: a preclinical and clinical study.
Topics: Animals; Antineoplastic Agents, Alkylating; Humans; Intravitreal Injections; Melphalan; Neoplasm Seeding; Rabbits; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan; Vitreous Body | 2022 |
Management of cataracts secondary to intravitreal chemotherapy injections for retinoblastoma seeding.
Topics: Antineoplastic Agents, Alkylating; Cataract; Child; Child, Preschool; Humans; Infant; Intravitreal Injections; Melphalan; Neoplasm Seeding; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan; Vitreous Body | 2022 |
Orbital Retinoblastoma Treated with Intra-arterial Chemotherapy.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Carboplatin; Child, Preschool; Drug Therapy, Combination; Humans; Infusions, Intra-Arterial; Magnetic Resonance Imaging; Male; Melphalan; Ophthalmic Artery; Orbital Neoplasms; Retinal Neoplasms; Retinoblastoma; Topoisomerase I Inhibitors; Topotecan | 2021 |
Biochemical measures of ovarian function in female survivors of retinoblastoma treated with intra-arterial melphalan: an initial report.
Topics: Carboplatin; Child; Electroretinography; Female; Humans; Infant; Infusions, Intra-Arterial; Melphalan; Ophthalmic Artery; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Survivors; Topotecan; Treatment Outcome | 2022 |
Preclinical validation of a novel therapeutic strategy for choroid plexus carcinoma.
Topics: Animals; Carcinoma; Child; Choroid Plexus Neoplasms; Humans; Mammals; Melphalan; Mice; Topotecan | 2023 |