Page last updated: 2024-08-24

topotecan and melphalan

topotecan has been researched along with melphalan in 90 studies

Research

Studies (90)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (4.44)	18.2507
2000's	13 (14.44)	29.6817
2010's	61 (67.78)	24.3611
2020's	12 (13.33)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Berger, NA; Chatterjee, S; Cheng, MF	1
Ali-Osman, F; Bigner, DD; Colvin, OM; Dolan, ME; Friedman, HS; Griffith, OW; Kaufmann, SH; Moschel, RC; Schold, SC	1
Bissery, MC; Cheshire, PJ; Hallman, JC; Houghton, JA; Houghton, PJ; Mathieu-Boué, A	1
Caserini, C; Orlandi, L; Silvestrini, R; Supino, R; Vaglini, M; Zaffaroni, N; Zunino, F	1
Aleman, AS; Bast, RC; Bevers, MW; Bodurka-Bevers, D; Burke, TW; Champlin, RE; Donato, ML; Freedman, RS; Gajewski, JL; Gershenson, DM; Ippoliti, CM; Levenback, CF; Wharton, JT; Wolf, JK	1
Anderson, JR; Barr, FG; Crist, WM; Donaldson, SS; Maurer, HM; Pappo, AS; Qualman, SJ; Raney, RB; Wiener, ES	1
Aleman, A; Alexanian, R; Anagnostopoulos, A; Champlin, RE; de Lima, M; Donato, ML; Giralt, S; Ippoliti, CM; Weber, D	1
Díaz, MA; González-Vicent, M; Lassaletta, A; Madero, L; Pérez-Martínez, A; Sevilla, J	1
Cheung, IY; Cheung, NK; Kramer, K; Kushner, BH; Modak, S	1
Al Harbi, T; Al-Faris, N; Doyle, J; Gassas, A; Goia, C; Pappo, A	1
Cheng, S; Evans, WK; Shepherd, FA; Stys-Norman, D	1
Barnhart, JR; Grigoryan, RS; Keshelava, N; Reynolds, CP; Yang, B	1
Aleman, A; Anderson, KO; Brown, J; Campagnaro, E; Cleeland, C; Giralt, S; Mendoza, F; Roden, L; Saliba, R; Weber, D	1
García-Sanz, R; González-López, TJ; Graciani, IF; Hermida, G; San Miguel, JF; Vázquez, L	1
Abramson, DH; Brodie, SE; Dunkel, IJ; Gobin, YP; Marr, B	2
Anderlini, P; Champlin, RE; Donato, M; Giralt, SA; Hosing, C; Kazmi, SM; Popat, U; Qazilbash, MH; Qureshi, S; Saliba, RM; Wang, M	1
Athanasopoulos, A; Daladimos, T; Karabelis, A; Kosmas, C; Mylonakis, N; Theotikos, E; Tsakonas, G	2
Castellano, A; De Ioris, MA; De Pasquale, MD; De Vito, R; Donfrancesco, A; Garganese, MC; Ilari, I; Inserra, A; Jenkner, A; Locatelli, F; Natali, G; Ravà, L	1
Kumabe, T; Niizuma, H; Osawa, S; Saito, R; Sonoda, Y; Tominaga, T; Watanabe, M	1
Glimelius, B; Lahn, M	1
Abramson, DH; Brodie, SE; Dunkel, IJ; Gobin, YP; Hung, C; Marr, BP	1
Abramson, DH; Brodie, SE; Dunkel, I; Gobin, YP; Marr, BP; Palioura, S	1
Abramson, DH; Brodie, SE; Dunkel, IJ; Gobin, YP; Marr, BP	1
Ceciliano, A; Chantada, GL; Dominguez, J; Fandino, AC; Millan, N; Schaiquevich, P; Taich, P; Villasante, F	1
Buitrago, E; Ceciliano, A; Chantada, GL; Fandino, A; Lucena, E; Romero, L; Sampor, C; Schaiquevich, P; Taich, P; Villasante, F	1
Abramson, DH; Brodie, SE; Dunkel, IJ; Francis, JH; Gobin, YP; Marr, BP; Riedel, ER	1
Arepalli, SA; Caywood, EH; Jabbour, P; Lally, SE; Manjandavida, FP; Pieretti, G; Shields, CL; Shields, JA	1
Ghadimi, H; Ghassemi, F; Khodabandeh, A; Roohipoor, R; Shields, CL	1
Maidana, DE; Pellegrini, M; Shields, CL; Shields, JA	1
Kamimura, S; Moritake, H; Nunoi, H; Takeshima, H; Yamada, A; Yamashita, S	1
Palanivelu, MS; Ramanjulu, R	1
Ghassemi, F; Khodabande, A; Shields, CL	1
Brennan, R; Kaste, SC; Orr, B; Tse, BC; Wilson, MW	1
Belmar, Á; Ossandón, D; Pérez, V; Shields, CL; Varas, M; Zanolli, M; Zúñiga, P	1
Lawson, BM; Saktanasate, J; Say, EA; Shields, CL	1
Dolz-Marco, R; Ferenczy, SR; Hasanreisoglu, M; Shields, CL; Shields, JA	1
Cao, C; Jabbour, PM; Pointdujour-Lim, R; Say, EA; Shields, CL; Shields, JA	1
Bansal, N; Koundanya, V; Ramamurthy, S; Ravikumar, R; Rishi, P; Saravanan, M; Sharma, T	1
Bertelli, E; Bracco, S; Cioni, S; De Francesco, S; Galluzzi, P; Gennari, P; Guglielmucci, D; Hadjistilianou, T; Leonini, S; Romano, DG; Tarantino, F; Vallone, IM; Venturi, C	1
Bracco, S; De Francesco, S; Galluzzi, P; Hadjistilianou, T; Menicacci, F; Motolese, E	1
Abruzzo, TA; Augsburger, JJ; Corrêa, ZM; Geller, JI; Lane, A; Michaels, ST	1
Beggache, M; Douglass, AM; Say, EA; Shields, CL; Shields, JA	1
Aisenbrey, S; Hagemann, U; Januschowski, K; Schnichels, S; Schrader, M; Süsskind, D	1
Abramson, DH; Brodie, SE; Dunkel, IJ; Fabius, AW; Francis, JH; Gobin, YP; Marr, BP; Mondesire-Crump, I	1
Hasanreisoglu, M; Iyer, PG; Jabbour, P; Lally, SE; Say, EA; Shields, CL; Shields, JA	1
Alset, AE; Caywood, E; Jabbour, P; Say, EA; Shields, CL; Shields, JA	1
Fuller, DG; Jabbour, PM; Khoo, CT; Magan, T; Shields, CL	1
Abramson, DH; Chantada, GL; Fabius, AW; Francis, JH; Schaiquevich, P	1
Abramson, DH; Brodie, SE; Francis, JH; Marr, B; Mondesire-Crump, I; Zabor, EC	1
Abramson, DH; Francis, JH; Iyer, S; Karl, MD; Marr, B	1
Beck-Popovic, M; Fabian, ID; Gaillard, MC; Munier, FL; Puccinelli, F	1
Chan, H; Gallie, BL; Halliday, W; Hèon, E; Shaikh, F; Soliman, SE	1
Aggarwal, V; Dhami, A; Maitray, A; Munusamy, S; Ramamurthy, S; Ravikumar, R; Rishi, P; Sharma, M; Sharma, T	1
Abramson, DH; Brodie, SE; Francis, JH; Gobin, YP; Iyer, S	1
Abramson, DH; Berry, JL; Cassoux, N; Francis, JH; Frenkel, S; Hadjistilianou, D; Ji, X; Munier, FL; Schefler, AC; Shields, CL; Teixeira, LF	1
Beck-Popovic, M; Gaillard, MC; Hadjistilianou, D; Maeder, P; Munier, FL; Puccinelli, F; Stathopoulos, C	1
Bogart, E; Chastagner, P; Cougnenc, O; Defachelles, AS; Ferry, I; Kolesnikov-Gauthier, H; Michon, J; Oudoux, A; Proust, S; Schleiermacher, G; Valteau-Couanet, D	1
Ceciliano, A; Chantada, GL; Fandiño, A; Funes, S; Lagomarsino, E; Manzitti, J; Neira, P; Peralta, L; Sampor, C; Schaiquevich, P; Sgroi, M; Villasante, F	1
Abramson, DH; Brodie, SE; Dunkel, IJ; Francis, JH; Gobin, YP; Levin, A; Mauguen, A; Mondesire-Crump, I; Rowlands, MA	1
Ancona-Lezama, D; Dalvin, LA; Jabbour, P; Lucio-Alvarez, JA; Masoomian, B; Shields, CL	1
Bosaleh, A; Chantada, G; Deu, A; Fandiño, A; Requejo, F; Rodriguez, A; Sampor, C; Schaiquevich, P; Sgroi, M; Zugbi, S	1
Ancona-Lezama, D; Dalvin, LA; Jabbour, P; Lucio-Alvarez, JA; Shields, CL	1
Beck-Popovic, M; Gaillard, MC; Moulin, A; Munier, FL; Puccinelli, F; Stathopoulos, C	1
Guo, L; Han, M; Li, J; Song, D; Wang, C; Wang, L; Wang, Z; Wu, C; Yang, Y; Zhao, J	1
Aroonroch, R; Boontawon, T; Chaitankar, V; Chittavanich, P; Hongeng, S; Jinawath, N; Kaewkhaw, R; Rojanaporn, D; Saengwimol, D; Thammachote, W	1
Abramson, DH; Brodie, S; Francis, JH; Gobin, YP; Levin, AM; McFadden, M	1
Blair, M; Kotlyar, B; Shapiro, M	1
Camp, DA; Lally, SE; Shields, CL	1
Cheon, JE; Choi, JY; Choi, YH; Hong, CR; Hong, KT; Kang, HJ; Kim, IH; Kim, SK; Lee, YJ; Park, JD; Park, KD; Park, SH; Phi, JH; Shin, HY; Wang, KC	1
Jabbour, P; Leahey, AM; Selzer, EB; Shields, CL; Welch, RJ	1
Akyüz, C; Kiratli, H; Koç, I; Öztürk, E; Varan, A	1
Ancona-Lezama, D; Baldassari, MP; Dalvin, LA; Das, S; Hammoud, B; Jabbour, P; Lim, LS; Ramesh, S; Shields, CL; Shivashankar, K; Sweid, A; Texakalidis, P; Tjoumakaris, S; Weinberg, JH; Xu, V	1
Abramson, DH; Brodie, SE; Francis, JH; Muca, E; Nadelmann, J	1
Daniels, AB; Friedman, DL; Froehler, MT; Zheng, Y	1
Borri, M; De Francesco, S; Hadjistilianou, T; Stacey, AW	1
Acosta, G; Fiani, B; Haynes, M; Nikolaidis, D; Rose, A; Runnels, J; Wong, A	1
Abramson, DH; Bogan, CM; Boyd, KL; Bridges, TM; Calcutt, MW; Chen, SC; Daniels, AB; Francis, JH; Friedman, DL; Hsieh, T; Kaczmarek, JV; Liao, A; Lindsley, CW; Nadelmann, JB; Pierce, JM; Richmond, A	1
Kıratlı, H; Koç, İ; Lotfisadigh, S; Taylan Şekeroğlu, H	1
Abramson, DH; Francis, JH; Gobin, YP	1
Abramson, DH; Antal, Z; Dunkel, IJ; Francis, JH; Friedman, DN; Gobin, YP; Marathe, PH	1
Beck, E; Dahmane, N; Garman, T; Hagen, N; Holland, D; Klumpp-Thomas, C; Laramee, M; Martin, B; McKnight, C; Souweidane, M; Thomas, CJ; Wang, A; Wilson, K; Xu, X; Zhang, X	1
Badel, JN; Bogart, E; Corradini, N; Cougnenc, O; Courbon, F; Defachelles, AS; Deley, MCL; Gambart, M; Giraudet, AL; Kolesnikov-Gauthier, H; Oudoux, A; Rault, E; Schleiermacher, G; Sevrin, F; Valteau-Couanet, D	1

Reviews

7 review(s) available for topotecan and melphalan

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Rhabdomyosarcoma and undifferentiated sarcoma in the first two decades of life: a selective review of intergroup rhabdomyosarcoma study group experience and rationale for Intergroup Rhabdomyosarcoma Study V. Journal of pediatric hematology/oncology, 2001, Volume: 23, Issue:4 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Disease-Free Survival; Doxorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Ifosfamide; Infant; Male; Melphalan; Multicenter Studies as Topic; Neoplasm Recurrence, Local; Neoplasm Staging; Pilot Projects; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Rhabdomyosarcoma; Salvage Therapy; Sarcoma; Soft Tissue Neoplasms; Survival Rate; Topotecan; Treatment Outcome; Vincristine	2001
Chemotherapy for relapsed small cell lung cancer: a systematic review and practice guideline. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2007, Volume: 2, Issue:4 Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials, Phase III as Topic; Etoposide; Female; Humans; Infusions, Intravenous; Lomustine; Lung Neoplasms; Male; Maximum Tolerated Dose; Melphalan; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Ontario; Practice Guidelines as Topic; Prognosis; Randomized Controlled Trials as Topic; Salvage Therapy; Survival Analysis; Topotecan	2007
Double high-dose chemotherapy and stem cell transplantation in adult Wilms' tumor. Future oncology (London, England), 2010, Volume: 6, Issue:11 Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carboplatin; Cyclophosphamide; Etoposide; Fatal Outcome; Hematopoietic Stem Cell Transplantation; Humans; Ifosfamide; Male; Melphalan; Paclitaxel; Radiography; Salvage Therapy; Topotecan; Transplantation, Autologous; Wilms Tumor; Young Adult	2010
Window-of-opportunity trials to evaluate clinical activity of new molecular entities in oncology. Annals of oncology : official journal of the European Society for Medical Oncology, 2011, Volume: 22, Issue:8 Topics: Adult; Antineoplastic Agents; Child; Clinical Trials as Topic; Epirubicin; Etoposide; Humans; Melphalan; Molecular Targeted Therapy; Neoplasms; Topotecan	2011
OCULAR PHARMACOLOGY OF CHEMOTHERAPY FOR RETINOBLASTOMA. Retina (Philadelphia, Pa.), 2017, Volume: 37, Issue:1 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Clinical Trials as Topic; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Infusions, Intra-Arterial; Injections, Intraocular; Melphalan; Retinal Neoplasms; Retinoblastoma; Topotecan	2017
The role for intra-arterial chemotherapy for refractory retinoblastoma: a systematic review. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2021, Volume: 23, Issue:10 Topics: Antineoplastic Agents; Bronchial Spasm; Carboplatin; Drug Resistance, Neoplasm; Edema; Eyelashes; Febrile Neutropenia; Humans; Infusions, Intra-Arterial; Melphalan; Methotrexate; Nausea; Retinal Neoplasms; Retinoblastoma; Salvage Therapy; Topotecan; Vitreous Hemorrhage; Vomiting	2021

Trials

7 trial(s) available for topotecan and melphalan

Article	Year
High-dose topotecan, melphalan, and cyclophosphamide (TMC) with stem cell support: a new regimen for the treatment of advanced ovarian cancer. Gynecologic oncology, 2001, Volume: 82, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Melphalan; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms; Survival Rate; Topotecan	2001
High-dose topotecan, melphalan and cyclophosphamide (TMC) with stem cell support: a new regimen for the treatment of multiple myeloma. Leukemia & lymphoma, 2004, Volume: 45, Issue:4 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Melphalan; Middle Aged; Multiple Myeloma; Pilot Projects; Remission Induction; Survival Rate; Topotecan; Transplantation, Autologous; Treatment Outcome	2004
High-dose chemotherapy with autologous stem cell rescue for children with high risk and recurrent medulloblastoma and supratentorial primitive neuroectodermal tumors. Journal of neuro-oncology, 2005, Volume: 71, Issue:1 Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cerebellar Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Male; Medulloblastoma; Melphalan; Neoplasm Recurrence, Local; Neuroectodermal Tumors, Primitive; Peripheral Blood Stem Cell Transplantation; Radiotherapy, Adjuvant; Supratentorial Neoplasms; Thiotepa; Topotecan; Transplantation, Autologous; Treatment Outcome	2005
Superselective ophthalmic artery chemotherapy as primary treatment for retinoblastoma (chemosurgery). Ophthalmology, 2010, Volume: 117, Issue:8 Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Electroretinography; Female; Fluorescein Angiography; Follow-Up Studies; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Ophthalmic Artery; Prospective Studies; Retinal Neoplasms; Retinoblastoma; Topotecan; Treatment Outcome; Visual Acuity	2010
Phase II trial of high-dose topotecan, melphalan and CY with autologous stem cell support for multiple myeloma. Bone marrow transplantation, 2011, Volume: 46, Issue:4 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disease-Free Survival; Female; Graft Survival; Hematopoietic Stem Cell Transplantation; Humans; Male; Melphalan; Middle Aged; Multiple Myeloma; Recurrence; Remission Induction; Topotecan; Transplantation, Autologous; Treatment Outcome	2011
Feasibility of Busulfan Melphalan and Stem Cell Rescue After 131I-MIBG and Topotecan Therapy for Refractory or Relapsed Metastatic Neuroblastoma: The French Experience. Journal of pediatric hematology/oncology, 2018, Volume: 40, Issue:6 Topics: 3-Iodobenzylguanidine; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool; Female; France; Hematopoietic Stem Cell Transplantation; Humans; Male; Melphalan; Neoplasm Metastasis; Neuroblastoma; Risk Factors; Topotecan	2018
Phase II study of Pediatric blood & cancer, 2023, Volume: 70, Issue:11 Topics: 3-Iodobenzylguanidine; Adolescent; Busulfan; Child; Child, Preschool; Chronic Disease; Humans; Melphalan; Neoplasm Recurrence, Local; Neuroblastoma; Topotecan; Young Adult	2023

Other Studies

76 other study(ies) available for topotecan and melphalan

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations. European journal of medicinal chemistry, 2010, Volume: 45, Issue:4 Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water	2010
Schedule-dependent cytotoxicity of topotecan alone and in combination chemotherapy regimens. Oncology research, 1994, Volume: 6, Issue:6 Topics: Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Aphidicolin; Camptothecin; Carmustine; Cell Cycle; Cell Death; Cell Line; Cisplatin; Cricetinae; Cricetulus; DNA Damage; DNA Repair; DNA, Neoplasm; Doxorubicin; Drug Synergism; Etoposide; Fibroblasts; Hydroxyurea; Lung; Melphalan; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topotecan	1994
Elevated DNA polymerase alpha, DNA polymerase beta, and DNA topoisomerase II in a melphalan-resistant rhabdomyosarcoma xenograft that is cross-resistant to nitrosoureas and topotecan. Cancer research, 1994, Jul-01, Volume: 54, Issue:13 Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Camptothecin; Carmustine; DNA Polymerase I; DNA Polymerase II; DNA Topoisomerases, Type II; Drug Resistance; Drug Screening Assays, Antitumor; Female; Humans; Male; Melphalan; Mice; Mice, Inbred BALB C; Mice, Nude; Rhabdomyosarcoma; Topotecan; Transferases; Transplantation, Heterologous	1994
Therapeutic efficacy of the topoisomerase I inhibitor 7-ethyl-10-(4-[1-piperidino]-1-piperidino)-carbonyloxy-camptothecin against human tumor xenografts: lack of cross-resistance in vivo in tumors with acquired resistance to the topoisomerase I inhibitor Cancer research, 1993, Jun-15, Volume: 53, Issue:12 Topics: Adolescent; Adult; Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Child; Colonic Neoplasms; Drug Administration Schedule; Drug Resistance; Drug Screening Assays, Antitumor; Female; Humans; Irinotecan; Male; Melphalan; Mice; Mice, Inbred CBA; Neoplasm Transplantation; Rhabdomyosarcoma; Topotecan; Transplantation, Heterologous; Tumor Cells, Cultured; Vincristine	1993
Modulation of melphalan cytotoxic activity in human melanoma cell lines. Anti-cancer drugs, 1996, Volume: 7, Issue:5 Topics: Antineoplastic Agents, Alkylating; Blotting, Northern; Camptothecin; Drug Interactions; Enzyme Inhibitors; Ethacrynic Acid; Humans; Melanoma; Melphalan; Temperature; Topoisomerase I Inhibitors; Topotecan; Tumor Cells, Cultured	1996
High-dose cyclophosphamide inhibition of humoral immune response to murine monoclonal antibody 3F8 in neuroblastoma patients: broad implications for immunotherapy. Pediatric blood & cancer, 2007, Volume: 48, Issue:4 Topics: Adolescent; Adult; Animals; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antibody Formation; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunoglobulin G; Immunosuppressive Agents; Immunotherapy; Infant; Male; Melphalan; Mice; Neuroblastoma; Retrospective Studies; Thiotepa; Topotecan; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome; Vincristine; Whole-Body Irradiation	2007
Does consolidation with autologous stem cell transplantation improve the outcome of children with metastatic or relapsed Ewing sarcoma? Pediatric blood & cancer, 2007, Volume: 49, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Carboplatin; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Epirubicin; Etoposide; Follow-Up Studies; Humans; Ifosfamide; Infection Control; Kaplan-Meier Estimate; Melphalan; Neoplasm Recurrence, Local; Peripheral Blood Stem Cell Transplantation; Postoperative Care; Retrospective Studies; Risk; Salvage Therapy; Sarcoma, Ewing; Topotecan; Transplantation Conditioning; Transplantation, Autologous; Treatment Failure; Vincristine	2007
Flow cytometry analysis of single-strand DNA damage in neuroblastoma cell lines using the F7-26 monoclonal antibody. Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2007, Volume: 71, Issue:11 Topics: Antibodies, Monoclonal; Antineoplastic Agents; Apoptosis; Benzyl Compounds; Cell Line, Tumor; Child; DNA Damage; DNA, Single-Stranded; Enzyme Inhibitors; Fenretinide; Flow Cytometry; Gamma Rays; Humans; Hydrocarbons, Fluorinated; Hydrogen Peroxide; In Situ Nick-End Labeling; Melphalan; Neuroblastoma; Oxidants; Reactive Oxygen Species; Topotecan	2007
Symptom burden after autologous stem cell transplantation for multiple myeloma. Cancer, 2008, Apr-01, Volume: 112, Issue:7 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Combined Modality Therapy; Female; Hematopoietic Stem Cell Transplantation; Humans; Melphalan; Middle Aged; Multiple Myeloma; Prospective Studies; Remission Induction; Severity of Illness Index; Survival Rate; Thiotepa; Topotecan; Transplantation, Autologous; Tumor Burden	2008
The combination of thalidomide, cyclophosphamide and dexamethasone is potentially useful in highly resistant Hodgkin's lymphoma. European journal of haematology, 2010, Volume: 84, Issue:3 Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dacarbazine; Deoxycytidine; Dexamethasone; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Hodgkin Disease; Humans; Male; Mechlorethamine; Melphalan; Organoplatinum Compounds; Paclitaxel; Peripheral Blood Stem Cell Transplantation; Prednisolone; Prednisone; Procarbazine; Remission Induction; Rituximab; Salvage Therapy; Thalidomide; Topotecan; Transplantation, Autologous; Vidarabine; Vinblastine; Vincristine	2010
Bilateral superselective ophthalmic artery chemotherapy for bilateral retinoblastoma: tandem therapy. Archives of ophthalmology (Chicago, Ill. : 1960), 2010, Volume: 128, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Catheters, Indwelling; Electroretinography; Evoked Potentials, Visual; Female; Follow-Up Studies; Functional Laterality; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Ophthalmic Artery; Retina; Retinal Neoplasms; Retinoblastoma; Topotecan; Treatment Outcome	2010
Second high-dose chemotherapy intensification followed by hematopoietic stem cell transplantation applying a novel high-dose topotecan-based regimen in an adult Wilms' tumor patient: case report. Anti-cancer drugs, 2011, Volume: 22, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chemotherapy, Adjuvant; Cyclophosphamide; Dose-Response Relationship, Drug; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Kidney Neoplasms; Male; Melphalan; Nephrectomy; Topotecan; Wilms Tumor; Young Adult	2011
Short topotecan-based induction regimen in newly diagnosed high-risk neuroblastoma. European journal of cancer (Oxford, England : 1990), 2011, Volume: 47, Issue:4 Topics: Abdominal Neoplasms; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Etoposide; Female; Humans; Ifosfamide; Infant; Kaplan-Meier Estimate; Lomustine; Male; Melphalan; Mesna; Neuroblastoma; Pilot Projects; Risk Factors; Thoracic Neoplasms; Topotecan; Treatment Outcome	2011
Infratentorial brain metastases of pediatric non-epithelial malignant tumors: three case reports. Brain tumor pathology, 2011, Volume: 28, Issue:2 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Carboplatin; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Dactinomycin; Doxorubicin; Etoposide; Humans; Ifosfamide; Infant; Infratentorial Neoplasms; Irinotecan; Melphalan; Neoplasm Metastasis; Neuroblastoma; Rhabdomyosarcoma; Thiotepa; Topotecan; Vincristine	2011
Success of intra-arterial chemotherapy (chemosurgery) for retinoblastoma: effect of orbitovascular anatomy. Archives of ophthalmology (Chicago, Ill. : 1960), 2012, Volume: 130, Issue:2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Blood Flow Velocity; Carboplatin; Child; Child, Preschool; Female; Fluorescein Angiography; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Ophthalmic Artery; Orbit; Regional Blood Flow; Retinal Neoplasms; Retinoblastoma; Topotecan; Young Adult	2012
Ophthalmic artery chemosurgery for less advanced intraocular retinoblastoma: five year review. PloS one, 2012, Volume: 7, Issue:4 Topics: Adolescent; Adult; Antineoplastic Agents; Child; Child, Preschool; Disease-Free Survival; Eye; Follow-Up Studies; Humans; Infant; Melphalan; Ophthalmic Artery; Ophthalmologic Surgical Procedures; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan; Young Adult	2012
Three-drug intra-arterial chemotherapy using simultaneous carboplatin, topotecan and melphalan for intraocular retinoblastoma: preliminary results. The British journal of ophthalmology, 2012, Volume: 96, Issue:10 Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Infusions, Intra-Arterial; Male; Melphalan; Middle Aged; Pilot Projects; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topoisomerase I Inhibitors; Topotecan; Treatment Outcome; Young Adult	2012
Intra-arterial chemotherapy is more effective than sequential periocular and intravenous chemotherapy as salvage treatment for relapsed retinoblastoma. Pediatric blood & cancer, 2013, Volume: 60, Issue:5 Topics: Administration, Intravenous; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; Humans; Injections, Intra-Arterial; Injections, Intraocular; Male; Melphalan; Middle Aged; Neoplasm Recurrence, Local; Ophthalmic Artery; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Salvage Therapy; Topotecan; Treatment Outcome; Vincristine; Young Adult	2013
Clinical pharmacokinetics of intra-arterial melphalan and topotecan combination in patients with retinoblastoma. Ophthalmology, 2014, Volume: 121, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromatography, High Pressure Liquid; Female; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Ophthalmic Artery; Prospective Studies; Retinal Neoplasms; Retinoblastoma; Topotecan	2014
Electroretinogram monitoring of dose-dependent toxicity after ophthalmic artery chemosurgery in retinoblastoma eyes: six year review. PloS one, 2014, Volume: 9, Issue:1 Topics: Carboplatin; Electroretinography; Humans; Melphalan; Ophthalmic Artery; Retinal Neoplasms; Retinoblastoma; Topotecan; Treatment Outcome	2014
Intra-arterial chemotherapy for retinoblastoma in 70 eyes: outcomes based on the international classification of retinoblastoma. Ophthalmology, 2014, Volume: 121, Issue:7 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Female; Fluorescein Angiography; Follow-Up Studies; Humans; Infant; Infusions, Intra-Arterial; International Classification of Diseases; Male; Melphalan; Microscopy, Acoustic; Ophthalmic Artery; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan; Treatment Outcome; Young Adult	2014
Combined intravitreal melphalan and topotecan for refractory or recurrent vitreous seeding from retinoblastoma. JAMA ophthalmology, 2014, Volume: 132, Issue:8 Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Female; Humans; Infant; Intravitreal Injections; Male; Melphalan; Neoplasm Seeding; Recurrence; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan; Vitreous Body	2014
Choroidal thickness after intraarterial chemotherapy for retinoblastoma. Retina (Philadelphia, Pa.), 2014, Volume: 34, Issue:10 Topics: Antineoplastic Combined Chemotherapy Protocols; Atrophy; Case-Control Studies; Child; Child, Preschool; Choroid; Female; Fluorescein Angiography; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Organ Size; Retinal Neoplasms; Retinoblastoma; Tomography, Optical Coherence; Topotecan	2014
Proposed strategy for the use of high-dose chemotherapy with stem cell rescue and intrathecal topotecan without whole-brain irradiation for infantile classic medulloblastoma. Pediatric blood & cancer, 2014, Volume: 61, Issue:12 Topics: Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Female; Humans; Infant; Injections, Spinal; Medulloblastoma; Melphalan; Neoplasm Recurrence, Local; Prognosis; Stem Cell Transplantation; Topotecan; Transplantation, Autologous	2014
Is combination therapy for resistant vitreous seeds really essential? JAMA ophthalmology, 2015, Volume: 133, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Male; Melphalan; Neoplasm Seeding; Retinal Neoplasms; Topotecan; Vitreous Body	2015
Is combination therapy for resistant vitreous seeds really essential? - reply. JAMA ophthalmology, 2015, Volume: 133, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Male; Melphalan; Neoplasm Seeding; Retinal Neoplasms; Topotecan; Vitreous Body	2015
Enophthalmos and choroidal atrophy after intraophthalmic artery chemotherapy for retinoblastoma. Ophthalmology, 2015, Volume: 122, Issue:2 Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Atrophy; Chemotherapy, Cancer, Regional Perfusion; Choroid; Choroid Diseases; Combined Modality Therapy; Diseases in Twins; Enophthalmos; Female; Fluorescein Angiography; Humans; Infant; Laser Coagulation; Magnetic Resonance Imaging; Melphalan; Ophthalmic Artery; Retinal Neoplasms; Retinoblastoma; Scleritis; Topoisomerase I Inhibitors; Topotecan; Twins, Monozygotic	2015
Using cost-effective intra-arterial chemotherapy to treat retinoblastoma in Chile. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2014, Volume: 18, Issue:6 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chile; Cost-Benefit Analysis; Developing Countries; Drug Costs; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Retinal Neoplasms; Retinoblastoma; Topotecan	2014
Intravitreal chemotherapy provides control for massive vitreous seeding from retinoblastoma. Journal of pediatric ophthalmology and strabismus, 2014, Dec-12, Volume: 51 Online Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Eye Neoplasms; Female; Humans; Intravitreal Injections; Melphalan; Neoplasm Seeding; Retinal Neoplasms; Retinoblastoma; Topotecan; Vitreous Body	2014
Spectral Domain Optical Coherence Tomography Reveals Hidden Fovea Beneath Extensive Vitreous Seeding From Retinoblastoma. Retina (Philadelphia, Pa.), 2015, Volume: 35, Issue:7 Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Eye Neoplasms; Female; Fovea Centralis; Humans; Infusions, Intra-Arterial; Intravitreal Injections; Melphalan; Neoplasm Seeding; Retinal Neoplasms; Retinoblastoma; Tomography, Optical Coherence; Topotecan; Vitreous Body	2015
Rescue intra-arterial chemotherapy following retinoblastoma recurrence after initial intra-arterial chemotherapy. Journal francais d'ophtalmologie, 2015, Volume: 38, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Child, Preschool; Eye Enucleation; Female; Follow-Up Studies; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Neoplasm Recurrence, Local; Retinal Neoplasms; Retinoblastoma; Retinoscopy; Retreatment; Salvage Therapy; Topotecan; Treatment Failure; Treatment Outcome	2015
Intra-arterial chemotherapy for retinoblastoma: First Indian report. Indian journal of ophthalmology, 2015, Volume: 63, Issue:4 Topics: Antineoplastic Agents; Carboplatin; Child, Preschool; Dose-Response Relationship, Drug; Female; Fluorescein Angiography; Follow-Up Studies; Fundus Oculi; Humans; Incidence; India; Infant; Injections, Intra-Arterial; Male; Melphalan; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Time Factors; Topoisomerase I Inhibitors; Topotecan	2015
Identification of Intraorbital Arteries in Pediatric Age by High Resolution Superselective Angiography. Orbit (Amsterdam, Netherlands), 2015, Volume: 34, Issue:5 Topics: Angiography, Digital Subtraction; Antineoplastic Combined Chemotherapy Protocols; Carotid Artery, Internal; Child, Preschool; Humans; Infusions, Intra-Arterial; Melphalan; Ophthalmic Artery; Orbit; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan	2015
Alternated intra-arterial and intravitreal chemotherapy for advanced intraocular retinoblastoma: preliminary successful results without systemic chemotherapy. International ophthalmology, 2015, Volume: 35, Issue:6 Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Female; Humans; Infant; Injections, Intra-Arterial; Intravitreal Injections; Male; Melphalan; Neoplasm Seeding; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan	2015
Selective Ophthalmic Artery Infusion Chemotherapy for Advanced Intraocular Retinoblastoma: CCHMC Early Experience. Journal of pediatric hematology/oncology, 2016, Volume: 38, Issue:1 Topics: Adolescent; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Female; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Ophthalmic Artery; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan	2016
INTRAVITREOUS CHEMOTHERAPY FOR ACTIVE VITREOUS SEEDING FROM RETINOBLASTOMA: Outcomes After 192 Consecutive Injections. The 2015 Howard Naquin Lecture. Retina (Philadelphia, Pa.), 2016, Volume: 36, Issue:6 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Eye Neoplasms; Female; Follow-Up Studies; Humans; Infant; Intravitreal Injections; Male; Melphalan; Neoplasm Seeding; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan; Vitreous Body	2016
Toxic effects of melphalan, topotecan and carboplatin on retinal pigment epithelial cells. Acta ophthalmologica, 2016, Volume: 94, Issue:5 Topics: Antineoplastic Agents; Apoptosis; Carboplatin; Caspase 3; Caspase 7; Cell Count; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Melphalan; Microscopy, Phase-Contrast; Retinal Pigment Epithelium; Topoisomerase I Inhibitors; Topotecan	2016
Simultaneous Bilateral Ophthalmic Artery Chemosurgery for Bilateral Retinoblastoma (Tandem Therapy). PloS one, 2016, Volume: 11, Issue:6 Topics: Carboplatin; Child; Child, Preschool; Electroretinography; Female; Humans; Kaplan-Meier Estimate; Male; Melphalan; Ophthalmic Artery; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan	2016
Secondary and tertiary intra-arterial chemotherapy for massive persistent or recurrent subretinal retinoblastoma seeds following previous chemotherapy exposure: long-term tumor control and globe salvage in 30 eyes. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2016, Volume: 20, Issue:4 Topics: Antineoplastic Agents; Carboplatin; Child, Preschool; Female; Humans; Infant; Male; Melphalan; Neoplasm Recurrence, Local; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan	2016
Retinoblastoma Control With Primary Intra-arterial Chemotherapy: Outcomes Before and During the Intravitreal Chemotherapy Era. Journal of pediatric ophthalmology and strabismus, 2016, Sep-01, Volume: 53, Issue:5 Topics: Antineoplastic Agents, Alkylating; Child; Child, Preschool; Eye Enucleation; Female; Humans; Infant; Infusions, Intra-Arterial; Intravitreal Injections; Male; Melphalan; Neoplasm Seeding; Ophthalmic Artery; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topoisomerase I Inhibitors; Topotecan	2016
Intra-arterial Chemotherapy for Adult Onset Retinoblastoma in a 32-Year-Old Man. Journal of pediatric ophthalmology and strabismus, 2016, Jul-30, Volume: 53 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Combined Modality Therapy; Humans; Infusions, Intra-Arterial; Male; Melphalan; Neoplasm Recurrence, Local; Neoplasm Seeding; Retinal Neoplasms; Retinoblastoma; Topotecan; Ultrasonography; Visual Acuity; Vitreous Body	2016
Efficacy and Toxicity of Intravitreous Chemotherapy for Retinoblastoma: Four-Year Experience. Ophthalmology, 2017, Volume: 124, Issue:4 Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cohort Studies; Disease-Free Survival; Electroretinography; Female; Humans; Infant; Injections, Intraocular; Intravitreal Injections; Male; Melphalan; Neoplasm Seeding; Ophthalmic Artery; Ophthalmoscopy; Retina; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topoisomerase I Inhibitors; Topotecan; Treatment Outcome; Vitreous Body	2017
Intraocular Pressure Changes Following Intravitreal Melphalan and Topotecan for the Treatment of Retinoblastoma With Vitreous Seeding. Journal of pediatric ophthalmology and strabismus, 2017, May-01, Volume: 54, Issue:3 Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Intravitreal Injections; Male; Melphalan; Neoplasm Seeding; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topoisomerase I Inhibitors; Topotecan; Treatment Outcome; Vitreous Body; Young Adult	2017
Diagnosis and management of secondary epipapillary retinoblastoma. The British journal of ophthalmology, 2017, Volume: 101, Issue:10 Topics: Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carboplatin; Child, Preschool; Cryotherapy; Female; Humans; Hyperthermia, Induced; Infant; Infusions, Intra-Arterial; Male; Melphalan; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Tomography, Optical Coherence; Topotecan	2017
White orbital mass after enucleation for retinoblastoma: The power of illusion. Ophthalmic genetics, 2017, Volume: 38, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Catgut; Eye Enucleation; Fluorescein Angiography; Foreign-Body Reaction; Granuloma, Foreign-Body; Humans; Infant; Intravitreal Injections; Magnetic Resonance Imaging; Male; Melphalan; Neoplasm Staging; Orbital Diseases; Orbital Implants; Retinal Neoplasms; Retinoblastoma; Suture Techniques; Topotecan	2017
Intra-arterial chemotherapy for retinoblastoma: Two-year results from tertiary eye-care center in India. Indian journal of ophthalmology, 2017, Volume: 65, Issue:4 Topics: Antineoplastic Agents, Alkylating; Child, Preschool; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Incidence; India; Infant; Injections, Intra-Arterial; Male; Melphalan; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Time Factors; Topoisomerase I Inhibitors; Topotecan; Treatment Outcome; Ultrasonography	2017
Retinoblastoma Vitreous Seed Clouds (Class 3): A Comparison of Treatment with Ophthalmic Artery Chemosurgery with or without Intravitreous and Periocular Chemotherapy. Ophthalmology, 2017, Volume: 124, Issue:10 Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child, Preschool; Cohort Studies; Disease-Free Survival; Electroretinography; Female; Humans; Infusions, Intra-Arterial; Intravitreal Injections; Kaplan-Meier Estimate; Male; Melphalan; Neoplasm Seeding; Ophthalmic Artery; Retina; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan; Vitreous Body	2017
Risk of Extraocular Extension in Eyes With Retinoblastoma Receiving Intravitreous Chemotherapy. JAMA ophthalmology, 2017, 12-01, Volume: 135, Issue:12 Topics: Antineoplastic Agents; Child, Preschool; Cryotherapy; Female; Humans; Infant; Intravitreal Injections; Male; Melphalan; Methotrexate; Microscopy, Acoustic; Neoplasm Seeding; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Risk Factors; Topotecan	2017
Successful conservative treatment of massive choroidal relapse in 2 retinoblastoma patients monitored by ultrasound biomicroscopy and/or spectral domain optic coherence tomography. Ophthalmic genetics, 2018, Volume: 39, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Choroid Neoplasms; Conservative Treatment; Fatal Outcome; Female; Fluorescein Angiography; Humans; Infant; Infusions, Intra-Arterial; Magnetic Resonance Imaging; Melphalan; Microscopy, Acoustic; Neoplasm Recurrence, Local; Retinal Neoplasms; Retinoblastoma; Tomography, Optical Coherence; Topotecan	2018
Feasibility and results of an intraarterial chemotherapy program for the conservative treatment of retinoblastoma in Argentina. Pediatric blood & cancer, 2018, Volume: 65, Issue:8 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Argentina; Carboplatin; Child; Child, Preschool; Conservative Treatment; Disease-Free Survival; Feasibility Studies; Female; Humans; Infusions, Intra-Arterial; Male; Melphalan; Middle Aged; Neoplasm Recurrence, Local; Ophthalmic Artery; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan; Young Adult	2018
Total retinal detachments due to retinoblastoma: Outcomes following intra-arterial chemotherapy/ophthalmic artery chemosurgery. PloS one, 2018, Volume: 13, Issue:4 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child, Preschool; Electroretinography; Female; Follow-Up Studies; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Ophthalmic Artery; Retina; Retinal Detachment; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Survival Analysis; Topotecan; Treatment Outcome	2018
Ophthalmic Vascular Events after Primary Unilateral Intra-arterial Chemotherapy for Retinoblastoma in Early and Recent Eras. Ophthalmology, 2018, Volume: 125, Issue:11 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Female; Fluorescein Angiography; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Ophthalmoscopy; Retinal Diseases; Retinal Neoplasms; Retinal Vessels; Retinoblastoma; Retrospective Studies; Risk Factors; Topotecan; Ultrasonography; Young Adult	2018
Combined high-dose intra-arterial and intrathecal chemotherapy for the treatment of a case of extraocular retinoblastoma. Pediatric blood & cancer, 2018, Volume: 65, Issue:12 Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Central Nervous System Neoplasms; Child, Preschool; Humans; Infusions, Intra-Arterial; Injections, Spinal; Male; Melphalan; Retinal Neoplasms; Retinoblastoma; Topotecan	2018
OPHTHALMIC VASCULAR EVENTS AFTER INTRA-ARTERIAL CHEMOTHERAPY FOR RETINOBLASTOMA: Real-World Comparison Between Primary and Secondary Treatments. Retina (Philadelphia, Pa.), 2019, Volume: 39, Issue:12 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Choroid; Female; Fluorescein Angiography; Humans; Infant; Infant, Newborn; Infusions, Intra-Arterial; Male; Melphalan; Ophthalmic Artery; Retinal Diseases; Retinal Neoplasms; Retinal Vessels; Retinoblastoma; Retrospective Studies; Topotecan; Young Adult	2019
INTRAVITREAL ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR FOR THE MANAGEMENT OF NEOVASCULARIZATION IN RETINOBLASTOMA AFTER INTRAVENOUS AND/OR INTRAARTERIAL CHEMOTHERAPY: Long-Term Outcomes in a Series of 35 Eyes. Retina (Philadelphia, Pa.), 2019, Volume: 39, Issue:12 Topics: Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Female; Fluorescein Angiography; Humans; Infant; Infusions, Intra-Arterial; Infusions, Intravenous; Intravitreal Injections; Male; Melphalan; Microscopy, Acoustic; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Retinal Neoplasms; Retinal Neovascularization; Retinoblastoma; Retrospective Studies; Topotecan; Vascular Endothelial Growth Factor A	2019
Intra-arterial chemotherapy for unilateral advanced intraocular retinoblastoma: Results and short-term complications. Medicine, 2018, Volume: 97, Issue:42 Topics: Antineoplastic Agents; Child, Preschool; Eye; Female; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Meningeal Arteries; Ophthalmic Artery; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan; Treatment Outcome	2018
A three-dimensional organoid model recapitulates tumorigenic aspects and drug responses of advanced human retinoblastoma. Scientific reports, 2018, 10-23, Volume: 8, Issue:1 Topics: Antineoplastic Agents; Carcinogenesis; Child, Preschool; DNA Copy Number Variations; Gene Expression Regulation, Neoplastic; Humans; Infant; Melphalan; Models, Biological; Neoplasm Staging; Organoids; Retinal Neoplasms; Retinoblastoma; Topotecan	2018
Association of electroretinography with visual outcomes after ophthalmic artery chemosurgery for retinoblastoma in ICRb D and E eyes. PloS one, 2019, Volume: 14, Issue:1 Topics: Carboplatin; Case-Control Studies; Child; Child, Preschool; Electroretinography; Female; Humans; Infant; Infant, Newborn; Male; Melphalan; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan; Visual Acuity	2019
Exudative Retinal Detachment Following Intravitreal Chemotherapeutic Treatment for Retinoblastoma. Ophthalmic surgery, lasers & imaging retina, 2019, 04-01, Volume: 50, Issue:4 Topics: Antineoplastic Agents, Alkylating; Child, Preschool; Drug Therapy, Combination; Fluorescein Angiography; Follow-Up Studies; Fundus Oculi; Humans; Injections, Intraocular; Intravitreal Injections; Macula Lutea; Male; Melphalan; Retinal Detachment; Retinal Neoplasms; Retinoblastoma; Topoisomerase I Inhibitors; Topotecan; Triamcinolone Acetonide; Ultrasonography	2019
Heterochromia following intravitreal chemotherapy in two cases. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2019, Volume: 23, Issue:4 Topics: Diagnosis, Differential; Drug Therapy, Combination; Female; Humans; Infant; Intravitreal Injections; Iris Diseases; Melphalan; Pigmentation Disorders; Retinal Neoplasms; Retinoblastoma; Tomography, Optical Coherence; Topotecan	2019
Tandem high-dose chemotherapy with topotecan-thiotepa-carboplatin and melphalan-etoposide-carboplatin regimens for pediatric high-risk brain tumors. International journal of clinical oncology, 2019, Volume: 24, Issue:12 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Child; Child, Preschool; Etoposide; Female; Humans; Infant; Male; Melphalan; Retrospective Studies; Stem Cell Transplantation; Survival Rate; Thiotepa; Topotecan; Transplantation, Autologous; Treatment Outcome	2019
Management of retinoblastoma in older children (>5 years) using intra-arterial chemotherapy: Comparison of outcomes to prechemotherapy and intravenous chemotherapy eras. Indian journal of ophthalmology, 2019, Volume: 67, Issue:12 Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Carboplatin; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Intravitreal Injections; Male; Melphalan; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topoisomerase I Inhibitors; Topotecan; Treatment Outcome; Young Adult	2019
Comparison of intravitreal melphalan with and without topotecan in the management of vitreous disease in retinoblastoma. Japanese journal of ophthalmology, 2020, Volume: 64, Issue:4 Topics: Antineoplastic Agents, Alkylating; Child, Preschool; Drug Therapy, Combination; Eye Diseases; Eye Enucleation; Female; Follow-Up Studies; Humans; Infant; Intravitreal Injections; Kaplan-Meier Estimate; Male; Melphalan; Neoplasm Seeding; Proportional Hazards Models; Retinal Diseases; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topoisomerase I Inhibitors; Topotecan; Treatment Outcome; Vitreous Body	2020
Intra-Arterial Chemotherapy for Retinoblastoma in Infants ≤10 kg: 74 Treated Eyes with 222 IAC Sessions. AJNR. American journal of neuroradiology, 2020, Volume: 41, Issue:7 Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan; Treatment Outcome	2020
Is intravitreal topotecan toxic to retinal function? The British journal of ophthalmology, 2021, Volume: 105, Issue:7 Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Electroretinography; Female; Follow-Up Studies; Humans; Infant; Intravitreal Injections; Male; Melphalan; Retina; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topoisomerase I Inhibitors; Topotecan	2021
Intra-arterial Chemotherapy as Primary Treatment for Cavitary Retinoblastoma: Excellent Response in Eight Tumors. Ophthalmology. Retina, 2021, Volume: 5, Issue:5 Topics: Antineoplastic Agents; Carboplatin; Female; Fluorescein Angiography; Follow-Up Studies; Fundus Oculi; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Time Factors; Topoisomerase I Inhibitors; Topotecan; Treatment Outcome; Ultrasonography	2021
The Addition of Topotecan to Melphalan in the Treatment of Retinoblastoma with Intra-arterial Chemotherapy. Ophthalmology. Retina, 2021, Volume: 5, Issue:8 Topics: Antineoplastic Agents, Alkylating; Child, Preschool; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluorescein Angiography; Follow-Up Studies; Fundus Oculi; Humans; Infant; Injections, Intra-Arterial; Male; Melphalan; Prospective Studies; Retina; Retinal Neoplasms; Retinoblastoma; Topoisomerase I Inhibitors; Topotecan; Treatment Outcome	2021
Evaluation of intravitreal topotecan dose levels, toxicity and efficacy for retinoblastoma vitreous seeds: a preclinical and clinical study. The British journal of ophthalmology, 2022, Volume: 106, Issue:2 Topics: Animals; Antineoplastic Agents, Alkylating; Humans; Intravitreal Injections; Melphalan; Neoplasm Seeding; Rabbits; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan; Vitreous Body	2022
Management of cataracts secondary to intravitreal chemotherapy injections for retinoblastoma seeding. European journal of ophthalmology, 2022, Volume: 32, Issue:3 Topics: Antineoplastic Agents, Alkylating; Cataract; Child; Child, Preschool; Humans; Infant; Intravitreal Injections; Melphalan; Neoplasm Seeding; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Topotecan; Vitreous Body	2022
Orbital Retinoblastoma Treated with Intra-arterial Chemotherapy. Ophthalmology, 2021, Volume: 128, Issue:10 Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Carboplatin; Child, Preschool; Drug Therapy, Combination; Humans; Infusions, Intra-Arterial; Magnetic Resonance Imaging; Male; Melphalan; Ophthalmic Artery; Orbital Neoplasms; Retinal Neoplasms; Retinoblastoma; Topoisomerase I Inhibitors; Topotecan	2021
Biochemical measures of ovarian function in female survivors of retinoblastoma treated with intra-arterial melphalan: an initial report. Ophthalmic genetics, 2022, Volume: 43, Issue:6 Topics: Carboplatin; Child; Electroretinography; Female; Humans; Infant; Infusions, Intra-Arterial; Melphalan; Ophthalmic Artery; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Survivors; Topotecan; Treatment Outcome	2022
Preclinical validation of a novel therapeutic strategy for choroid plexus carcinoma. Journal of controlled release : official journal of the Controlled Release Society, 2023, Volume: 357 Topics: Animals; Carcinoma; Child; Choroid Plexus Neoplasms; Humans; Mammals; Melphalan; Mice; Topotecan	2023