Page last updated: 2024-08-24

topotecan and hydroxyurea

topotecan has been researched along with hydroxyurea in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's4 (50.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Berger, NA; Chatterjee, S; Cheng, MF1
Annan, RS; Carr, SA; Chaturvedi, P; Eng, WK; Faucette, LF; Hurle, MR; Johnson, RK; Li, X; Lu, Q; Mattern, MR; Mishra, R; Scott, GF; Winkler, JD; Zhang, X; Zhou, BB; Zhu, Y1
Battmer, K; Dammann, E; Eder, M; Ganser, A; Hambach, L; Heil, G; Hertenstein, B; Stucki, A1
Chan, GC; Law, HK; Li, J; Liu, YL1

Reviews

2 review(s) available for topotecan and hydroxyurea

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Donor cell-derived acute myeloid leukemia developing 14 months after matched unrelated bone marrow transplantation for chronic myeloid leukemia.
    Bone marrow transplantation, 2001, Volume: 28, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Bone Marrow Transplantation; Combined Modality Therapy; Cyclosporine; Cystitis; Cytarabine; Cytomegalovirus Infections; DNA, Neoplasm; Female; Foscarnet; Ganciclovir; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Histocompatibility; Humans; Hydroxyurea; Immunosuppressive Agents; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Methotrexate; Mitoxantrone; Neoplasms, Second Primary; Prednisolone; Prostaglandins; Remission Induction; Topotecan; Transplantation Conditioning; Transplantation, Homologous; Vidarabine; Whole-Body Irradiation

2001

Other Studies

6 other study(ies) available for topotecan and hydroxyurea

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Schedule-dependent cytotoxicity of topotecan alone and in combination chemotherapy regimens.
    Oncology research, 1994, Volume: 6, Issue:6

    Topics: Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Aphidicolin; Camptothecin; Carmustine; Cell Cycle; Cell Death; Cell Line; Cisplatin; Cricetinae; Cricetulus; DNA Damage; DNA Repair; DNA, Neoplasm; Doxorubicin; Drug Synergism; Etoposide; Fibroblasts; Hydroxyurea; Lung; Melphalan; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topotecan

1994
Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway.
    Oncogene, 1999, Jul-15, Volume: 18, Issue:28

    Topics: Alkylating Agents; Animals; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Cycle Proteins; Cells, Cultured; Checkpoint Kinase 2; Cloning, Molecular; DNA Damage; DNA Repair; DNA-Binding Proteins; DNA, Complementary; DNA, Fungal; Enzyme Inhibitors; Fungal Proteins; Gamma Rays; Genetic Complementation Test; Humans; Hydroxyurea; Phosphorylation; Protein Kinases; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proteins; ras-GRF1; Rats; Saccharomyces cerevisiae; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Signal Transduction; Species Specificity; Topoisomerase I Inhibitors; Topotecan; Tumor Suppressor Proteins

1999
[Effect of cisplatin, topotecan, daunorubicin and hydroxyurea on human mesenchymal stem cells].
    Zhongguo shi yan xue ye xue za zhi, 2010, Volume: 18, Issue:4

    Topics: Antineoplastic Agents; Bone Marrow Cells; Cells, Cultured; Cisplatin; Daunorubicin; Humans; Hydroxyurea; Inhibitory Concentration 50; Mesenchymal Stem Cells; Topotecan

2010