topotecan has been researched along with homocamptothecin in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bigg, DC; Camara, J; Demarquay, D; Harnett, J; Kasprzyk, PG; Lavergne, O; Lesueur-Ginot, L; Pla Rodas, F; Pommier, J; Pons, D; Prévost, G; Rolland, A; Schiano-Liberatore, AM; Ulibarri, G | 1 |
| Battistuzzi, G; Beretta, GL; Cabri, W; De Cesare, M; Giannini, G; Marastoni, E; Marzi, M; Pisano, C; Vesci, L; Zunino, F | 1 |
| Huang, Q; Lu, W; Wang, L | 1 |
| Bigg, DC; Bronckart, Y; Chaboteaux, C; da Costa, PM; Decaestecker, C; Gordover, L; Harper, L; Kiss, R; Lavergne, O; Lesueur-Ginot, L; Malonne, H; Philippart, P | 1 |
| Yang, S; Zhang, WN | 1 |
| Cheng, P; Dong, G; Guo, W; Lei, N; Liu, W; Miao, Z; Sheng, C; Yao, J; Zhang, W; Zhang, X; Zhu, L; Zhuang, C | 1 |
2 review(s) available for topotecan and homocamptothecin
| Article | Year |
|---|---|
Evolution in medicinal chemistry of E-ring-modified Camptothecin analogs as anticancer agents.
Topics: Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Structure-Activity Relationship; Topoisomerase I Inhibitors | 2013 |
[Homocamptothecins--novel promising anticancer drugs as inhibitors of topoisomerase I].
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; DNA Damage; Humans; Irinotecan; Topoisomerase I Inhibitors; Topotecan; Tumor Cells, Cultured | 2004 |
4 other study(ies) available for topotecan and homocamptothecin
| Article | Year |
|---|---|
Homocamptothecins: synthesis and antitumor activity of novel E-ring-modified camptothecin analogues.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzoxepins; Camptothecin; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Humans; Inhibitory Concentration 50; Male; Mice; Mice, Nude; Neoplasm Transplantation; Stereoisomerism; Structure-Activity Relationship; Topoisomerase I Inhibitors; Transplantation, Heterologous; Tumor Cells, Cultured | 1998 |
E-ring-modified 7-oxyiminomethyl camptothecins: Synthesis and preliminary in vitro and in vivo biological evaluation.
Topics: Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type I; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Stereoisomerism; Structure-Activity Relationship; Xenograft Model Antitumor Assays | 2008 |
Homocamptothecin, an E-ring-modified camptothecin, exerts more potent antiproliferative activity than other topoisomerase I inhibitors in human colon cancers obtained from surgery and maintained in vitro under histotypical culture conditions.
Topics: Antineoplastic Agents; Biopsy; Camptothecin; Cell Division; Colon; Colonic Neoplasms; Culture Techniques; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; Etoposide; Humans; Irinotecan; Thymidine; Topoisomerase I Inhibitors; Topotecan; Tritium; Tumor Cells, Cultured | 2000 |
Synthesis and biological evaluation of 7-alkenyl homocamptothecins as potent topoisomerase I inhibitors.
Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Cell Line, Tumor; DNA; DNA Cleavage; DNA Topoisomerases, Type I; Humans; Topoisomerase I Inhibitors; Topotecan | 2012 |