Page last updated: 2024-08-24

topotecan and genz-644282

topotecan has been researched along with genz-644282 in 2 studies

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Houghton, PJ; LaVoie, EJ; Liu, A; Liu, LF; Ruchelman, AL; Zhou, N	1
Anders Kolb, E; Billups, CA; Carol, H; Gorlick, R; Houghton, PJ; Kang, MH; Keir, ST; Lock, R; Madden, SL; Maris, JM; Morton, CL; Reynolds, CP; Smith, MA; Teicher, BA; Zhang, MX	1

Other Studies

2 other study(ies) available for topotecan and genz-644282

Article	Year
5-(2-aminoethyl)dibenzo[c,h][1,6]naphthyridin-6-ones: variation of n-alkyl substituents modulates sensitivity to efflux transporters associated with multidrug resistance. Journal of medicinal chemistry, 2005, Feb-10, Volume: 48, Issue:3 Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cell Line, Tumor; DNA Topoisomerases, Type I; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Mice; Mice, SCID; Naphthyridines; Piperazines; Piperidines; Pyrrolidines; Structure-Activity Relationship; Transplantation, Heterologous	2005
Testing of the topoisomerase 1 inhibitor Genz-644282 by the pediatric preclinical testing program. Pediatric blood & cancer, 2012, Volume: 58, Issue:2 Topics: Animals; Cell Proliferation; Child; Disease-Free Survival; DNA Topoisomerases, Type I; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, SCID; Naphthyridines; Neoplasms, Experimental; Survival Rate; Topoisomerase I Inhibitors; Topotecan; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2012

Article

Year

5-(2-aminoethyl)dibenzo[c,h][1,6]naphthyridin-6-ones: variation of n-alkyl substituents modulates sensitivity to efflux transporters associated with multidrug resistance.

Journal of medicinal chemistry, 2005, Feb-10, Volume: 48, Issue:3

Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cell Line, Tumor; DNA Topoisomerases, Type I; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Mice; Mice, SCID; Naphthyridines; Piperazines; Piperidines; Pyrrolidines; Structure-Activity Relationship; Transplantation, Heterologous

2005

Testing of the topoisomerase 1 inhibitor Genz-644282 by the pediatric preclinical testing program.

Pediatric blood & cancer, 2012, Volume: 58, Issue:2

Topics: Animals; Cell Proliferation; Child; Disease-Free Survival; DNA Topoisomerases, Type I; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, SCID; Naphthyridines; Neoplasms, Experimental; Survival Rate; Topoisomerase I Inhibitors; Topotecan; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2012