Page last updated: 2024-08-24

topotecan and genz-644282

topotecan has been researched along with genz-644282 in 2 studies

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Houghton, PJ; LaVoie, EJ; Liu, A; Liu, LF; Ruchelman, AL; Zhou, N1
Anders Kolb, E; Billups, CA; Carol, H; Gorlick, R; Houghton, PJ; Kang, MH; Keir, ST; Lock, R; Madden, SL; Maris, JM; Morton, CL; Reynolds, CP; Smith, MA; Teicher, BA; Zhang, MX1

Other Studies

2 other study(ies) available for topotecan and genz-644282

ArticleYear
5-(2-aminoethyl)dibenzo[c,h][1,6]naphthyridin-6-ones: variation of n-alkyl substituents modulates sensitivity to efflux transporters associated with multidrug resistance.
    Journal of medicinal chemistry, 2005, Feb-10, Volume: 48, Issue:3

    Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cell Line, Tumor; DNA Topoisomerases, Type I; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Mice; Mice, SCID; Naphthyridines; Piperazines; Piperidines; Pyrrolidines; Structure-Activity Relationship; Transplantation, Heterologous

2005
Testing of the topoisomerase 1 inhibitor Genz-644282 by the pediatric preclinical testing program.
    Pediatric blood & cancer, 2012, Volume: 58, Issue:2

    Topics: Animals; Cell Proliferation; Child; Disease-Free Survival; DNA Topoisomerases, Type I; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, SCID; Naphthyridines; Neoplasms, Experimental; Survival Rate; Topoisomerase I Inhibitors; Topotecan; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2012