Page last updated: 2024-08-24

topotecan and cladribine

topotecan has been researched along with cladribine in 10 studies

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (40.00)	29.6817
2010's	6 (60.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP	1
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Argentieri, D; Falotico, R; Parry, TJ; Siekierka, J; Tallarida, RJ; Thyagarajan, R	1
Crews, KR; Inaba, H; Pounds, S; Pui, CH; Razzouk, BI; Ribeiro, RC; Rubnitz, JE; Stewart, CF; Yang, S	1
Adamkiewicz-Drożyńska, E; Bączek, T; Balcerska, A; Belka, M; Konieczna, L; Maciejka-Kapuścińska, L; Niedźwiecki, M; Wachowiak, J; Wiśniewski, J	1
Chao, Z; Chen, XM; Deng, CX; DU, X; Huang, X; Lai, PL; Li, MM; Liao, PJ; Ling, W; Lu, ZS; Wan, CC; Wang, YL; Weng, JY; Wu, SJ; Zhong, LY; Zou, XL	1

Reviews

1 review(s) available for topotecan and cladribine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for topotecan and cladribine

Article	Year
Combination of cladribine plus topotecan for recurrent or refractory pediatric acute myeloid leukemia. Cancer, 2010, Jan-01, Volume: 116, Issue:1 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cladribine; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Recurrence; Retreatment; Topotecan	2010

Article

Year

Combination of cladribine plus topotecan for recurrent or refractory pediatric acute myeloid leukemia.

Cancer, 2010, Jan-01, Volume: 116, Issue:1

Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cladribine; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Recurrence; Retreatment; Topotecan

2010

Other Studies

8 other study(ies) available for topotecan and cladribine

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations. European journal of medicinal chemistry, 2010, Volume: 45, Issue:4 Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water	2010
Identification of potent Yes1 kinase inhibitors using a library screening approach. Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15 Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship	2013
Effects of drug combinations on smooth muscle cell proliferation: an isobolographic analysis. European journal of pharmacology, 2006, Feb-17, Volume: 532, Issue:1-2 Topics: Algorithms; Cell Proliferation; Cell Survival; Cells, Cultured; Cladribine; Coronary Vessels; Dose-Response Relationship, Drug; Drug Synergism; Etoposide; Growth Inhibitors; Humans; Myocytes, Smooth Muscle; Sirolimus; Topotecan	2006
Topotecan exposure estimation in pediatric acute myeloid leukemia supported by LC-MS-based drug monitoring and pharmacokinetic analysis. Journal of pharmaceutical and biomedical analysis, 2012, Volume: 70 Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Calibration; Chromatography, Liquid; Chromatography, Reverse-Phase; Cladribine; Drug Dosage Calculations; Drug Monitoring; Female; Half-Life; Humans; Leukemia, Myeloid, Acute; Limit of Detection; Linear Models; Metabolic Clearance Rate; Recurrence; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Topoisomerase I Inhibitors; Topotecan	2012
[Effectiveness of CLAT Protocol for Treating Patients with Refractory Acute Myeloid Leukemia]. Zhongguo shi yan xue ye xue za zhi, 2016, Volume: 24, Issue:2 Topics: Adolescent; Adult; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Thrombocytopenia; Topotecan; Young Adult	2016