Compounds > topotecan
Page last updated: 2024-08-24

topotecan and amlodipine

topotecan has been researched along with amlodipine in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Hong, HY; Li, X; Liang, GW; Liu, Y; Long, C; Lu, WL; Ma, X; Ruan, GR; Wang, JC; Yuan, L; Zhang, Q; Zhang, X; Zhang, YT1
Hong, HY; Li, X; Liang, GW; Liu, Y; Long, C; Lu, WL; Ruan, GR; Wang, JC; Zhang, Q; Zhang, X; Zhang, YT1

Reviews

1 review(s) available for topotecan and amlodipine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

5 other study(ies) available for topotecan and amlodipine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
A novel stealth liposomal topotecan with amlodipine: apoptotic effect is associated with deletion of intracellular Ca2+ by amlodipine thus leading to an enhanced antitumor activity in leukemia.
    Journal of controlled release : official journal of the Controlled Release Society, 2006, May-15, Volume: 112, Issue:2

    Topics: Amlodipine; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Calcium; Caspases; Cell Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; HL-60 Cells; Humans; K562 Cells; Leukemia; Liposomes; Microscopy, Confocal; Topotecan

2006
Effect of stealthy liposomal topotecan plus amlodipine on the multidrug-resistant leukaemia cells in vitro and xenograft in mice.
    European journal of clinical investigation, 2006, Volume: 36, Issue:6

    Topics: Amlodipine; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspases; Cell Division; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Leukemia; Liposomes; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Topotecan; Transplantation, Heterologous; Tumor Cells, Cultured

2006