toosendanin has been researched along with u-50488 in 1 studies
| Studies (toosendanin) | Trials (toosendanin) | Recent Studies (post-2010) (toosendanin) | Studies (u-50488) | Trials (u-50488) | Recent Studies (post-2010) (u-50488) |
|---|---|---|---|---|---|
| 115 | 0 | 72 | 1,664 | 3 | 209 |
| Protein | Taxonomy | toosendanin (IC50) | u-50488 (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 2.15 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.0027 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 2.15 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.7171 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0958 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.0537 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, J; Chen, S; He, L; Huang, L; Li, W; Liu, H; Liu, R; Wang, F; Wang, H; Wen, C; Yang, X; Yu, WK; Zhou, Q | 1 |
1 other study(ies) available for toosendanin and u-50488
| Article | Year |
|---|---|
Toosendanin-induced apoptosis in colorectal cancer cells is associated with the κ-opioid receptor/β-catenin signaling axis.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; beta Catenin; Cell Line, Tumor; Colorectal Neoplasms; Drug Resistance, Neoplasm; Drugs, Chinese Herbal; Female; Fluorouracil; G1 Phase Cell Cycle Checkpoints; Humans; Mice, Inbred BALB C; Molecular Docking Simulation; Receptors, Opioid, kappa; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2020 |