Compounds > toosendanin
Page last updated: 2024-09-03

toosendanin and nifedipine

toosendanin has been researched along with nifedipine in 4 studies

Compound Research Comparison

Studies
(toosendanin)		Trials
(toosendanin)		Recent Studies (post-2010)
(toosendanin)		Studies
(nifedipine)		Trials
(nifedipine)		Recent Studies (post-2010) (nifedipine)
11507216,0242,4961,505

Protein Interaction Comparison

ProteinTaxonomytoosendanin (IC50)nifedipine (IC50)
perilipin-5Homo sapiens (human)7.133
perilipin-1Homo sapiens (human)9.619
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform aHomo sapiens (human)8.376
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)0.0429
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.035
Cytochrome P450 1A2Homo sapiens (human)0.3
Cytochrome P450 3A4Homo sapiens (human)10
Adenosine receptor A3Homo sapiens (human)7.214
Cytochrome P450 2C9 Homo sapiens (human)3.06
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)10
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)7.214
Voltage-dependent L-type calcium channel subunit alpha-1CRattus norvegicus (Norway rat)0.0385
Potassium voltage-gated channel subfamily A member 5Homo sapiens (human)6.1
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Rattus norvegicus (Norway rat)1.12
Adenosine receptor A1Homo sapiens (human)7.701
3-oxo-5-alpha-steroid 4-dehydrogenase 2Rattus norvegicus (Norway rat)1.12
C-C chemokine receptor type 2Homo sapiens (human)2.191
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)7.214
Cytochrome P450 2J2Homo sapiens (human)3.06
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.4733
Voltage-dependent L-type calcium channel subunit alpha-1CMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1SMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.035
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.0394
Myosin light chain kinase, smooth muscleHomo sapiens (human)2.02
Potassium channel subfamily K member 2 Bos taurus (cattle)8.2
Indoleamine 2,3-dioxygenase 2Mus musculus (house mouse)1.5
Voltage-dependent L-type calcium channel subunit alpha-1DMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1FMus musculus (house mouse)1.2

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hu, Q; Huang, F; Shi, Y1
Ding, J; Shi, YL; Xu, TH2
Li, MF; Shi, YL1

Other Studies

4 other study(ies) available for toosendanin and nifedipine

ArticleYear
Inhibition of Toosendanin on the delayed rectifier potassium current in neuroblastoma x glioma NG108-15 cells.
    Brain research, 1997, Mar-14, Volume: 751, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Delayed Rectifier Potassium Channels; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glioma; Hybrid Cells; Mice; Neuroblastoma; Neuromuscular Blocking Agents; Nifedipine; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Rats; Tetraethylammonium; Tetraethylammonium Compounds; Verapamil

1997
Different effects of toosendanin on perineurially recorded Ca(2+) currents in mouse and frog motor nerve terminals.
    Neuroscience research, 2001, Volume: 41, Issue:3

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Drugs, Chinese Herbal; Electric Conductivity; Mice; Nerve Endings; Neuromuscular Blocking Agents; Neuromuscular Junction; Nifedipine; Ranidae

2001
Toosendanin increases free-Ca(2+) concentration in NG108-15 cells via L-type Ca(2+) channels.
    Acta pharmacologica Sinica, 2004, Volume: 25, Issue:5

    Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Cell Differentiation; Drugs, Chinese Herbal; Glioma; Hybrid Cells; Neuroblastoma; Nifedipine; Tumor Cells, Cultured

2004
The long-term effect of toosendanin on current through nifedipine-sensitive Ca2+ channels in NG108-15 cells.
    Toxicon : official journal of the International Society on Toxinology, 2005, Volume: 45, Issue:1

    Topics: Animals; Barium; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Line, Tumor; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Membrane Potentials; Nifedipine; omega-Conotoxins; Time Factors

2005