Page last updated: 2024-09-05

tolvaptan and warfarin

tolvaptan has been researched along with warfarin in 3 studies

Compound Research Comparison

Studies (tolvaptan)	Trials (tolvaptan)	Recent Studies (post-2010) (tolvaptan)	Studies (warfarin)	Trials (warfarin)	Recent Studies (post-2010) (warfarin)
967	172	786	36,573	2,143	14,728

Protein Interaction Comparison

Protein	Taxonomy	tolvaptan (IC50)	warfarin (IC50)
Vitamin K epoxide reductase complex subunit 1	Homo sapiens (human)		0.0088

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (66.67)	24.3611
2020's	1 (33.33)	2.80

Authors

Authors	Studies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Ajioka, M; Iwao, T; Saito, M; Suzuki, T	1
Ichihara, T; Iwao, T; Maeda, T; Saito, M; Suzuki, T	1

Reviews

1 review(s) available for tolvaptan and warfarin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

2 other study(ies) available for tolvaptan and warfarin

Article	Year
Enhancement of Warfarin Anticoagulant Reaction in Patients with Repeated Oral Tolvaptan Administration. Biological & pharmaceutical bulletin, 2018, Jul-01, Volume: 41, Issue:7 Topics: Administration, Oral; Anticoagulants; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Cardiovascular Diseases; Drug Interactions; Drug Therapy, Combination; Female; Humans; International Normalized Ratio; Male; Prothrombin Time; Retrospective Studies; Tolvaptan; Warfarin	2018
[The Effect of Increased Free Concentrations of Warfarin Due to Protein-binding Substitution in a Combination of Tolvaptan on the PT-INR]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2020, Oct-01, Volume: 140, Issue:10 Topics: Administration, Oral; Aged; Aged, 80 and over; Albumins; Anticoagulants; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; In Vitro Techniques; International Normalized Ratio; Male; Middle Aged; Protein Binding; Prothrombin Time; Time Factors; Tolvaptan; Warfarin	2020

Article

Year

Enhancement of Warfarin Anticoagulant Reaction in Patients with Repeated Oral Tolvaptan Administration.

Biological & pharmaceutical bulletin, 2018, Jul-01, Volume: 41, Issue:7

Topics: Administration, Oral; Anticoagulants; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Cardiovascular Diseases; Drug Interactions; Drug Therapy, Combination; Female; Humans; International Normalized Ratio; Male; Prothrombin Time; Retrospective Studies; Tolvaptan; Warfarin

2018

[The Effect of Increased Free Concentrations of Warfarin Due to Protein-binding Substitution in a Combination of Tolvaptan on the PT-INR].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2020, Oct-01, Volume: 140, Issue:10

Topics: Administration, Oral; Aged; Aged, 80 and over; Albumins; Anticoagulants; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; In Vitro Techniques; International Normalized Ratio; Male; Middle Aged; Protein Binding; Prothrombin Time; Time Factors; Tolvaptan; Warfarin

2020