Compounds > tolvaptan
Page last updated: 2024-09-05

tolvaptan and tezosentan

tolvaptan has been researched along with tezosentan in 3 studies

Compound Research Comparison

Studies
(tolvaptan)		Trials
(tolvaptan)		Recent Studies (post-2010)
(tolvaptan)		Studies
(tezosentan)		Trials
(tezosentan)		Recent Studies (post-2010) (tezosentan)
9671727861572933

Protein Interaction Comparison

ProteinTaxonomytolvaptan (IC50)tezosentan (IC50)
Endothelin receptor type BHomo sapiens (human)0.021
Endothelin-1 receptorHomo sapiens (human)0.0205

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dunlap, ME; Ibrahim, OA1
Gheorghiade, M; Mebazaa, A; Teerlink, JR1
Ambrosy, AP; Butler, J; Gheorghiade, M; Greene, SJ; Vaduganathan, M1

Reviews

3 review(s) available for tolvaptan and tezosentan

ArticleYear
Combination pharmacologic therapies for heart failure: what next after angiotensin-converting enzyme inhibitors and beta-blockers?
    Current heart failure reports, 2005, Volume: 2, Issue:2

    Topics: Acetanilides; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Clinical Trials as Topic; Drug Therapy, Combination; Enzyme Inhibitors; Heart Failure; Humans; Hydralazine; Isosorbide Dinitrate; Mineralocorticoid Receptor Antagonists; Piperazines; Pyridines; Ranolazine; Tetrazoles; Tolvaptan; Vasodilator Agents

2005
Pharmacology of new agents for acute heart failure syndromes.
    The American journal of cardiology, 2005, Sep-19, Volume: 96, Issue:6A

    Topics: Acute Disease; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Cardiotonic Agents; Clinical Trials as Topic; Endothelin Receptor Antagonists; Heart Failure; Humans; Hydrazones; Pyridazines; Pyridines; Simendan; Syndrome; Tetrazoles; Tolvaptan; Vasodilator Agents

2005
The disconnect between phase II and phase III trials of drugs for heart failure.
    Nature reviews. Cardiology, 2013, Volume: 10, Issue:2

    Topics: Animals; Benzazepines; Cardiovascular Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Evidence-Based Medicine; Heart Failure; Humans; Hydrazones; Natriuretic Peptide, Brain; Patient Readmission; Patient Selection; Pyridazines; Pyridines; Risk Assessment; Risk Factors; Simendan; Tetrazoles; Time Factors; Tolvaptan; Treatment Outcome; Xanthines

2013