Page last updated: 2024-09-05

tolvaptan and sitagliptin

tolvaptan has been researched along with sitagliptin in 2 studies

Compound Research Comparison

Studies
(tolvaptan)
Trials
(tolvaptan)
Recent Studies (post-2010)
(tolvaptan)
Studies
(sitagliptin)
Trials
(sitagliptin)
Recent Studies (post-2010) (sitagliptin)
96717278697070

Protein Interaction Comparison

ProteinTaxonomytolvaptan (IC50)sitagliptin (IC50)
Chain A, Dipeptidyl peptidase IVHomo sapiens (human)0.018
Dipeptidyl peptidase 4Rattus norvegicus (Norway rat)0.0255
Thromboxane-A synthase Homo sapiens (human)0.0194
Dipeptidyl peptidase 4Homo sapiens (human)0.0236
Dipeptidyl peptidase 4Mus musculus (house mouse)0.046
Prolyl endopeptidase FAPHomo sapiens (human)2.93
Dipeptidyl peptidase 8Homo sapiens (human)0.4715
Dipeptidyl peptidase 9Homo sapiens (human)1.539
Dipeptidyl peptidase 2Homo sapiens (human)0.022

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for tolvaptan and sitagliptin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

1 other study(ies) available for tolvaptan and sitagliptin

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013