Page last updated: 2024-09-05

tolvaptan and omega-n-methylarginine

tolvaptan has been researched along with omega-n-methylarginine in 2 studies

Compound Research Comparison

Studies
(tolvaptan)
Trials
(tolvaptan)
Recent Studies (post-2010)
(tolvaptan)
Studies
(omega-n-methylarginine)
Trials
(omega-n-methylarginine)
Recent Studies (post-2010) (omega-n-methylarginine)
9671727864,411344336

Protein Interaction Comparison

ProteinTaxonomytolvaptan (IC50)omega-n-methylarginine (IC50)
Neutrophil elastaseHomo sapiens (human)0.3
Proteinase-activated receptor 1Homo sapiens (human)0.0018
Nitric oxide synthase, endothelialBos taurus (cattle)7
Nitric oxide synthase, endothelialHomo sapiens (human)2.9489
Nitric oxide synthase, brainHomo sapiens (human)3.3983
Nitric oxide synthase, brain Rattus norvegicus (Norway rat)7.5
Nitric oxide synthase, inducibleMus musculus (house mouse)2.3
Nitric oxide synthase, inducibleHomo sapiens (human)2.9252
Collagenase 3Homo sapiens (human)0.3
Nitric oxide synthase, brainMus musculus (house mouse)4.3

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Al Therwani, S; Bech, JN; Jensen, JM; Mose, FH; Pedersen, EB1
Al Therwani, S; Bech, JN; Mose, FH; Pedersen, EB; Rosenbæk, JB1

Trials

2 trial(s) available for tolvaptan and omega-n-methylarginine

ArticleYear
Effect of vasopressin antagonism on renal handling of sodium and water and central and brachial blood pressure during inhibition of the nitric oxide system in healthy subjects.
    BMC nephrology, 2014, Jun-25, Volume: 15

    Topics: Adolescent; Adult; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Blood Pressure; Body Water; Brachial Artery; Cross-Over Studies; Double-Blind Method; Female; Humans; Kidney; Male; Nitric Oxide; omega-N-Methylarginine; Placebo Effect; Reference Values; Sodium; Tolvaptan; Vasopressins; Young Adult

2014
Effect of tolvaptan on renal water and sodium excretion and blood pressure during nitric oxide inhibition: a dose-response study in healthy subjects.
    BMC nephrology, 2017, Mar-13, Volume: 18, Issue:1

    Topics: Adult; Benzazepines; Blood Pressure; Body Water; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Glomerular Filtration Rate; Humans; Kidney; Nitric Oxide; omega-N-Methylarginine; Placebo Effect; Sodium; Tolvaptan; Water-Electrolyte Balance

2017