tolvaptan has been researched along with captopril in 3 studies
| Studies (tolvaptan) | Trials (tolvaptan) | Recent Studies (post-2010) (tolvaptan) | Studies (captopril) | Trials (captopril) | Recent Studies (post-2010) (captopril) |
|---|---|---|---|---|---|
| 967 | 172 | 786 | 10,320 | 1,514 | 890 |
| Protein | Taxonomy | tolvaptan (IC50) | captopril (IC50) |
|---|---|---|---|
| Leukotriene A-4 hydrolase | Homo sapiens (human) | 3.6 | |
| Angiotensin-converting enzyme | Homo sapiens (human) | 0.084 | |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | 0.0173 | |
| Succinyl-diaminopimelate desuccinylase | Haemophilus influenzae Rd KW20 | 3.3 | |
| Angiotensin-converting enzyme | Rattus norvegicus (Norway rat) | 0.1004 | |
| Beta-lactamase | Pseudomonas aeruginosa | 5 | |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | 0.011 | |
| Beta-lactamase class B VIM-2 | Pseudomonas aeruginosa | 3.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Amat, C; Cristià , E; Moretó, M; Naftalin, RJ | 1 |
1 review(s) available for tolvaptan and captopril
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 other study(ies) available for tolvaptan and captopril
| Article | Year |
|---|---|
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Role of vasopressin in rat distal colon function.
Topics: Actins; Aldosterone; Animals; Antidiuretic Agents; Antidiuretic Hormone Receptor Antagonists; Aquaporin 2; Arginine Vasopressin; Benzazepines; Captopril; Colon; Dextrans; Diet, Sodium-Restricted; Drinking; Epithelial Sodium Channels; Fibroblasts; Fluorescein-5-isothiocyanate; Hormone Antagonists; Intestinal Mucosa; Male; Microscopy, Confocal; Osmolar Concentration; Potassium; Rats; Rats, Sprague-Dawley; Sodium; Tolvaptan | 2007 |