tolvaptan has been researched along with amiloride in 2 studies
| Studies (tolvaptan) | Trials (tolvaptan) | Recent Studies (post-2010) (tolvaptan) | Studies (amiloride) | Trials (amiloride) | Recent Studies (post-2010) (amiloride) |
|---|---|---|---|---|---|
| 967 | 172 | 786 | 7,584 | 339 | 788 |
| Protein | Taxonomy | tolvaptan (IC50) | amiloride (IC50) |
|---|---|---|---|
| Urokinase-type plasminogen activator | Homo sapiens (human) | 4.7 | |
| Urokinase-type plasminogen activator | Mus musculus (house mouse) | 2.3 | |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | 3.909 | |
| Sodium/hydrogen exchanger 1 | Rattus norvegicus (Norway rat) | 1 | |
| Amiloride-sensitive sodium channel subunit alpha | Homo sapiens (human) | 0.776 | |
| Sodium/hydrogen exchanger 2 | Oryctolagus cuniculus (rabbit) | 1 | |
| Acid-sensing ion channel 3 | Homo sapiens (human) | 4.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Fujiki, H; Nivens, E; Pinto, CS; Reif, GA; Wallace, DP; Yamaguchi, T | 1 |
1 review(s) available for tolvaptan and amiloride
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 other study(ies) available for tolvaptan and amiloride
| Article | Year |
|---|---|
Tolvaptan inhibits ERK-dependent cell proliferation, Cl⁻ secretion, and in vitro cyst growth of human ADPKD cells stimulated by vasopressin.
Topics: Adult; Aged; Amiloride; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Blotting, Western; Cell Proliferation; Cells, Cultured; Chlorides; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Cysts; Diuretics; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Male; Middle Aged; Polycystic Kidney, Autosomal Dominant; Renal Agents; Tolvaptan; Vasopressins | 2011 |