Page last updated: 2024-09-05

tolvaptan and acetaminophen

tolvaptan has been researched along with acetaminophen in 3 studies

Compound Research Comparison

Studies (tolvaptan)	Trials (tolvaptan)	Recent Studies (post-2010) (tolvaptan)	Studies (acetaminophen)	Trials (acetaminophen)	Recent Studies (post-2010) (acetaminophen)
967	172	786	20,696	2,848	8,242

Protein Interaction Comparison

Protein	Taxonomy	tolvaptan (IC50)	acetaminophen (IC50)
Myoglobin	Homo sapiens (human)		2.3

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (66.67)	24.3611
2020's	1 (33.33)	2.80

Authors

Authors	Studies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Dixon, D; Fallon, JK; Liu, J; Mosedale, M; Nautiyal, M; Qasem, RJ; Smith, PC; Wolf, KK	1

Reviews

1 review(s) available for tolvaptan and acetaminophen

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

2 other study(ies) available for tolvaptan and acetaminophen

Article	Year
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Characterization of primary mouse hepatocyte spheroids as a model system to support investigations of drug-induced liver injury. Toxicology in vitro : an international journal published in association with BIBRA, 2021, Volume: 70 Topics: Acetaminophen; Adenosine Triphosphate; Albumins; Animals; Arabinofuranosyluracil; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Female; Hepatocytes; Male; Mice, Inbred C57BL; Models, Biological; Phenylacetates; Proteomics; Spheroids, Cellular; Sulfonamides; Tolvaptan; Transcriptome	2021

Article

Year

A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.

Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013

Characterization of primary mouse hepatocyte spheroids as a model system to support investigations of drug-induced liver injury.

Toxicology in vitro : an international journal published in association with BIBRA, 2021, Volume: 70

Topics: Acetaminophen; Adenosine Triphosphate; Albumins; Animals; Arabinofuranosyluracil; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Female; Hepatocytes; Male; Mice, Inbred C57BL; Models, Biological; Phenylacetates; Proteomics; Spheroids, Cellular; Sulfonamides; Tolvaptan; Transcriptome

2021