toluene has been researched along with nutlin-3a in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 10 (83.33) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, H; Jiang, H; Saha, MN | 1 |
| Chen, B; Longtine, MS; Nelson, DM; Sadovsky, Y | 1 |
| Abayasekara, N; Berliner, N; Currie, T; Dutt, S; Ebert, BL; Khanna-Gupta, A; Kutok, JL; Lin, K; Megerdichian, C; Mullally, A; Narla, A; Wilson, FH | 1 |
| Chen, C; Dong, D; Li, Z; Lin, H; Lu, Y; Luo, X; Wang, Z; Xiao, J; Yang, B | 1 |
| Abdel-Malek, Z; Chen, J; Chen, S; Cheng, T; Jameson, J; Kadakia, M; Kadekaro, AL; Swope, VB; Yang, J | 1 |
| Kim, HS; Lee, SY; Shin, SJ | 1 |
| Nishijima, F; Niwa, T; Shimizu, H; Yisireyili, M | 1 |
| Aydin, S; Hampp, S; Ireno, IC; Selivanova, G; Stahl, AI; Troester, MA; Wiehe, RS; Wiesmüller, L | 1 |
| Aghajan, M; Aung Than, T; Hu, H; Huo, Y; Kaplowitz, N; Win, S; Yan, M; Yin, S | 1 |
| Ganeshan, L; Jin, XL; O'Neill, C | 1 |
| Ahmed, A; Bezzerides, VJ; Cho, A; Escalante, GO; Garbern, JC; Helman, A; Kim, SL; Lee, RT; MacQueen, L; Melton, DA; Ogurlu, R; Parker, KK; Sarikhani, M; Sereda, R; Zimmerman, JF | 1 |
| Peuget, S; Selivanova, G; Singh, M; Zhu, J | 1 |
12 other study(ies) available for toluene and nutlin-3a
| Article | Year |
|---|---|
Molecular mechanisms of nutlin-induced apoptosis in multiple myeloma: evidence for p53-transcription-dependent and -independent pathways.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Benzothiazoles; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Immunoblotting; Multiple Myeloma; Piperazines; Protein Binding; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-mdm2; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sulfonamides; Toluene; Transcription, Genetic; Tumor Suppressor Protein p53 | 2010 |
Hypoxia downregulates p53 but induces apoptosis and enhances expression of BAD in cultures of human syncytiotrophoblasts.
Topics: Animals; Apoptosis; bcl-Associated Death Protein; Benzothiazoles; Cells, Cultured; Down-Regulation; Enzyme Inhibitors; Female; Gene Expression Regulation; Humans; Hypoxia; Imidazoles; Oxygen; Piperazines; Pregnancy; Staurosporine; Toluene; Trophoblasts; Tumor Suppressor Protein p53 | 2010 |
Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells.
Topics: Anemia, Diamond-Blackfan; Anemia, Macrocytic; Animals; Benzothiazoles; Cell Cycle; Cell Lineage; Cell Nucleolus; Chromosome Deletion; Chromosomes, Human, Pair 5; Cyclin-Dependent Kinase Inhibitor p21; Erythroid Precursor Cells; Haploinsufficiency; Hematopoiesis; Humans; Imidazoles; Mice; Mice, Inbred BALB C; Myelodysplastic Syndromes; Piperazines; Protein Binding; Proto-Oncogene Proteins c-mdm2; Ribosomal Proteins; RNA, Small Interfering; Toluene; Tumor Suppressor Protein p53 | 2011 |
Transcriptional and post-transcriptional mechanisms for oncogenic overexpression of ether à go-go K+ channel.
Topics: Benzothiazoles; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation; E2F1 Transcription Factor; Electrophoretic Mobility Shift Assay; Ether-A-Go-Go Potassium Channels; Humans; Imidazoles; MicroRNAs; Oligodeoxyribonucleotides, Antisense; Piperazines; Reverse Transcriptase Polymerase Chain Reaction; Toluene; Tumor Suppressor Protein p53 | 2011 |
Alpha-melanocyte-stimulating hormone suppresses oxidative stress through a p53-mediated signaling pathway in human melanocytes.
Topics: alpha-MSH; Benzothiazoles; Blotting, Western; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; DNA Damage; DNA Glycosylases; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Activated Protein Kinase; Histones; Humans; Hydrogen Peroxide; Imidazoles; Melanocytes; Oxidants; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Piperazines; Receptor, Melanocortin, Type 1; RNA Interference; Signal Transduction; Toluene; Tumor Suppressor Protein p53; Ultraviolet Rays | 2012 |
ERK1/2 activation mediated by the nutlin‑3‑induced mitochondrial translocation of p53.
Topics: Antioxidants; Apoptosis; Benzothiazoles; Butadienes; Cell Line, Tumor; Cyclic N-Oxides; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Humans; Imidazoles; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitochondria; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Osteosarcoma; Phosphorylation; Piperazines; Protein Transport; Quinazolines; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Toluene; Tumor Suppressor Protein p53; Tyrphostins | 2013 |
Indoxyl sulfate enhances p53-TGF-β1-Smad3 pathway in proximal tubular cells.
Topics: Actins; Analysis of Variance; Animals; Benzothiazoles; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Humans; Imidazoles; Indican; Kidney Tubules, Proximal; Male; Phosphorylation; Piperazines; Rats; Rats, Inbred Dahl; RNA, Messenger; Signal Transduction; Smad3 Protein; Toluene; Transforming Growth Factor beta1; Tumor Suppressor Protein p53; Up-Regulation | 2013 |
Modulation of the poly (ADP-ribose) polymerase inhibitor response and DNA recombination in breast cancer cells by drugs affecting endogenous wild-type p53.
Topics: Benzothiazoles; Breast Neoplasms; Cell Line, Tumor; Enzyme Inhibitors; Female; Gene Knockdown Techniques; Genes, p53; Humans; Imidazoles; Isoquinolines; Molecular Weight; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Recombinational DNA Repair; RNA, Small Interfering; Toluene | 2014 |
Protective role of p53 in acetaminophen hepatotoxicity.
Topics: Acetaminophen; Animals; Benzothiazoles; Chemical and Drug Induced Liver Injury; Gene Knockdown Techniques; Gene Knockout Techniques; Hepatocytes; Humans; Imidazoles; Liver; MAP Kinase Kinase 4; Mice; Oligonucleotides, Antisense; Piperazines; Signal Transduction; Toluene; Tumor Suppressor Protein p53 | 2017 |
The induction of tumour suppressor protein P53 limits the entry of cells into the pluripotent inner cell mass lineage in the mouse embryo.
Topics: Animals; Apoptosis; Benzothiazoles; Blastocyst; Cell Lineage; Embryonic Development; Gene Expression Regulation, Developmental; Genes, Homeobox; Imidazoles; Mice, Transgenic; Piperazines; Proto-Oncogene Proteins c-mdm2; Signal Transduction; Toluene; Tumor Suppressor Protein p53 | 2017 |
Inhibition of mTOR Signaling Enhances Maturation of Cardiomyocytes Derived From Human-Induced Pluripotent Stem Cells via p53-Induced Quiescence.
Topics: Benzothiazoles; Cell Line; Humans; Imidazoles; Induced Pluripotent Stem Cells; Myocytes, Cardiac; Naphthyridines; Piperazines; Toluene; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53; Wnt Signaling Pathway | 2020 |
Pifithrin-α alters p53 post-translational modifications pattern and differentially inhibits p53 target genes.
Topics: Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Benzothiazoles; Cell Cycle; Cell Line, Tumor; Cell Proliferation; HCT116 Cells; Humans; Imidazoles; MCF-7 Cells; NF-E2-Related Factor 2; Piperazines; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-mdm2; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; RNA Interference; RNA, Small Interfering; Toluene; Transcription, Genetic; Tumor Suppressor Protein p53 | 2020 |