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toluene 2,4-diisocyanate and substance p

toluene 2,4-diisocyanate has been researched along with substance p in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19903 (18.75)18.7374
1990's10 (62.50)18.2507
2000's2 (12.50)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boniotti, A; Graf, PD; Mapp, CE; Nadel, JA1
Gordon, T; Scypinski, LA; Sheppard, D; Thompson, JE1
Borson, DB; Dusser, D; Nadel, JA; Scypinski, L; Sheppard, D; Thompson, JE1
Scypinski, L; Sheppard, D1
Takeda, N1
CalabrĂ², F; Chitano, P; Di Blasi, P; Fabbri, LM; Lucchini, RE; Maestrelli, P; Mapp, CE; Saetta, M1
Abe, Y; Irifune, M; Kalubi, B; Matsunaga, T; Ogino, S; Takeda, N1
Ikeda, H; Kitajiri, M; Kubo, N; Kumazawa, T; Sato, K1
Baur, X; Marcynski, B; Marek, W; Potthast, JJ1
Buckley, TL; Muis, T; Nijkamp, FP; Scheerens, H; Van Loveren, H1
Qiao, J; Tao, Z; Xiao, J; Zhao, C; Zhao, S1
Tao, Z; Xiao, J; Zhao, C1
Chitano, P; Fabbri, LM; Jovine, L; Lucchini, RE; Maestrelli, P; Mapp, CE; Miotto, D; Polak, J; Saetta, M; Springall, DR1
Dey, RD; Fedan, JS; Huang, J; Hunter, DD; Satterfield, BE1
Dey, RD; Wilfong, ER1
Asano, K; Kashiwabara, M; Kobayashi, H; Mizuyoshi, T1

Other Studies

16 other study(ies) available for toluene 2,4-diisocyanate and substance p

ArticleYear
Toluene diisocyanate contracts guinea pig bronchial smooth muscle by activating capsaicin-sensitive sensory nerves.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Bronchi; Capsaicin; Glycopeptides; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; Neurons, Afferent; Substance P; Toluene 2,4-Diisocyanate

1991
Tachykinins mediate the acute increase in airway responsiveness caused by toluene diisocyanate in guinea pigs.
    The American review of respiratory disease, 1987, Volume: 136, Issue:1

    Topics: Acetylcholine; Airway Resistance; Animals; Capsaicin; Cyanates; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Guinea Pigs; Male; Neuropeptides; Pulmonary Edema; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Tachykinins; Toluene 2,4-Diisocyanate; Trachea

1987
Toluene diisocyanate increases airway responsiveness to substance P and decreases airway neutral endopeptidase.
    The Journal of clinical investigation, 1988, Volume: 81, Issue:4

    Topics: Airway Resistance; Animals; Cyanates; Endopeptidases; Esophagus; Glycopeptides; Guinea Pigs; In Vitro Techniques; Lung; Neprilysin; Protease Inhibitors; Substance P; Toluene 2,4-Diisocyanate; Trachea

1988
A tachykinin receptor antagonist inhibits and an inhibitor of tachykinin metabolism potentiates toluene diisocyanate-induced airway hyperresponsiveness in guinea pigs.
    The American review of respiratory disease, 1988, Volume: 138, Issue:3

    Topics: Acetylcholine; Animals; Cyanates; Depression, Chemical; Drug Synergism; Glycopeptides; Guinea Pigs; Male; Receptors, Neurotransmitter; Receptors, Tachykinin; Respiratory Hypersensitivity; Substance P; Tachykinins; Toluene 2,4-Diisocyanate

1988
[Neurogenic inflammation in nasal hyperreactivity].
    Nihon Kyobu Shikkan Gakkai zasshi, 1993, Volume: 31 Suppl

    Topics: Animals; Calcitonin Gene-Related Peptide; Guinea Pigs; Male; Nerve Endings; Rhinitis, Allergic, Seasonal; Rhinitis, Vasomotor; Substance P; Toluene 2,4-Diisocyanate

1993
The effects of toluene diisocyanate and of capsaicin on human bronchial smooth muscle in vitro.
    European journal of pharmacology, 1994, Apr-04, Volume: 270, Issue:2-3

    Topics: Acetylcholine; Aged; Bronchi; Capsaicin; Female; Humans; In Vitro Techniques; Isoproterenol; Isotonic Contraction; Male; Middle Aged; Muscle Relaxation; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Physalaemin; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Toluene 2,4-Diisocyanate

1994
Neurogenic inflammation in nasal allergy: histochemical and pharmacological studies in guinea pigs. A review.
    Acta oto-laryngologica. Supplementum, 1993, Volume: 501

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Desensitization, Immunologic; Fluorescent Antibody Technique; Guinea Pigs; Male; Nerve Endings; Nerve Fibers; Neural Pathways; Neurons, Afferent; Nose Diseases; Nucleic Acid Hybridization; Respiratory Hypersensitivity; Substance P; Toluene 2,4-Diisocyanate; Trigeminal Ganglion

1993
Effects of topical capsaicin on autonomic nerves in experimentally-induced nasal hypersensitivity. An immunocytochemical study.
    Acta oto-laryngologica. Supplementum, 1993, Volume: 500

    Topics: Administration, Intranasal; Animals; Autonomic Nervous System; Calcitonin Gene-Related Peptide; Capsaicin; Disease Models, Animal; Female; Guinea Pigs; Nasal Mucosa; Olfactory Bulb; Rhinitis, Allergic, Perennial; Substance P; Toluene 2,4-Diisocyanate; Tyrosine 3-Monooxygenase

1993
Role of substance P and neurokinin A in toluene diisocyanate-induced increased airway responsiveness in rabbits.
    Lung, 1996, Volume: 174, Issue:2

    Topics: Acetylcholine; Administration, Inhalation; Airway Resistance; Animals; Bronchi; Bronchoconstriction; Capsaicin; Disease Models, Animal; Lung Diseases; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Occupational Diseases; Rabbits; Receptors, Neurokinin-2; Substance P; Toluene 2,4-Diisocyanate; Trachea

1996
The involvement of sensory neuropeptides in toluene diisocyanate-induced tracheal hyperreactivity in the mouse airways.
    British journal of pharmacology, 1996, Volume: 119, Issue:8

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Indoles; Isoindoles; Isometric Contraction; Male; Mice; Mice, Inbred BALB C; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Neuropeptides; Respiratory Hypersensitivity; Skin; Substance P; Tachykinins; Toluene 2,4-Diisocyanate; Tracheal Diseases

1996
Changes in tachykinin--ergic nerve terminal densities in rat nasal mucosa during hypersensitivity.
    Chinese medical journal, 1997, Volume: 110, Issue:2

    Topics: Animals; Female; Male; Nasal Mucosa; Nerve Endings; Neurokinin A; Neurokinin B; Rats; Rats, Wistar; Rhinitis, Allergic, Perennial; Substance P; Tachykinins; Toluene 2,4-Diisocyanate

1997
[Immunohistochemical study on three peptidergic terminals in nasal mucosa in a rat AR model].
    Zhonghua er bi yan hou ke za zhi, 1996, Volume: 31, Issue:4

    Topics: Animals; Female; Immunohistochemistry; Male; Nasal Mucosa; Neurokinin A; Neurokinin B; Rats; Rats, Wistar; Rhinitis, Allergic, Perennial; Substance P; Tachykinins; Toluene 2,4-Diisocyanate

1996
Immunization and challenge with toluene diisocyanate decrease tachykinin and calcitonin gene-related peptide immunoreactivity in guinea pig central airways.
    American journal of respiratory and critical care medicine, 1998, Volume: 158, Issue:1

    Topics: Animals; Bronchial Provocation Tests; Calcitonin Gene-Related Peptide; Cell Count; Disease Models, Animal; Eosinophils; Guinea Pigs; Immunization; Immunoglobulin G; Immunohistochemistry; Inflammation; Male; Nerve Fibers; Respiratory System; Substance P; Tachykinins; Toluene 2,4-Diisocyanate

1998
Toluene diisocyanate enhances substance P in sensory neurons innervating the nasal mucosa.
    American journal of respiratory and critical care medicine, 2000, Volume: 161, Issue:2 Pt 1

    Topics: Animals; Gene Expression; Irritants; Male; Nasal Mucosa; Protein Precursors; Rats; Rats, Inbred F344; RNA, Messenger; Substance P; Tachykinins; Toluene 2,4-Diisocyanate; Trigeminal Ganglion

2000
Nerve growth factor and substance P regulation in nasal sensory neurons after toluene diisocyanate exposure.
    American journal of respiratory cell and molecular biology, 2004, Volume: 30, Issue:6

    Topics: Animals; Biomarkers; Carbazoles; Enzyme Inhibitors; Indole Alkaloids; Male; Microspheres; Nasal Lavage Fluid; Nasal Mucosa; Nerve Growth Factor; Neurons, Afferent; Neutrophils; Rats; Rats, Sprague-Dawley; Receptor, trkA; Signal Transduction; Substance P; Toluene 2,4-Diisocyanate

2004
Suppression of neuropeptide production by quercetin in allergic rhinitis model rats.
    BMC complementary and alternative medicine, 2016, May-20, Volume: 16

    Topics: Animals; Anti-Allergic Agents; Calcitonin Gene-Related Peptide; Male; Nasal Lavage Fluid; Nerve Growth Factor; Neuropeptides; Quercetin; Rats; Rats, Sprague-Dawley; Rhinitis, Allergic; Substance P; Toluene 2,4-Diisocyanate

2016