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toluene 2,4-diisocyanate and methacholine chloride

toluene 2,4-diisocyanate has been researched along with methacholine chloride in 47 studies

Research

Studies (47)

Timeframe	Studies, this research(%)	All Research%
pre-1990	14 (29.79)	18.7374
1990's	14 (29.79)	18.2507
2000's	15 (31.91)	29.6817
2010's	4 (8.51)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Baur, X; Fruhmann, G; Vogelmeier, C	1
Bossi, MC; Candura, SM; Dellabianca, A; Moscato, G; Vinci, G	1
Baik, JH; Cho, DI; Cho, YS; Kim, JW; Park, HS; Park, JN; Rhu, NS	1
Banks, DE; Barkman, HW; Lopez, M; Salvaggio, JE; Sastre, J	1
Chiesura-Corona, P; Crescioli, S; De Marzo, N; Fabbri, LM; Mapp, CE; Picotti, G; Tossin, L	1
Boschetto, P; Bruchi, O; Cappellazzo, G; Fabbri, LM; Mapp, CE; Milani, GF; Pivirotto, F; Zocca, E	1
Boschetto, P; Crescioli, S; dal Vecchio, L; de Marzo, N; Fabbri, LM; Mapp, C; Paleari, D	1
Banks, DE; Rando, RJ	1
Corona, PC; De Marzo, N; Fabbri, L; Mapp, CE	1
Boschetto, P; Dal Vecchio, L; Fabbri, LM; Mapp, CE	1
Chiesura-Corona, P; Dal Vecchio, L; de Marzo, N; di Giacomo, GR; Fabbri, LM; Maestrelli, P; Mapp, CE; Zocca, E	1
Boschetto, P; Dal Vecchio, L; De Marzo, N; Fabbri, LM; Mapp, CE	1
Bernstein, IL; Brooks, SM; McKay, RT; Moller, DR	1
Bacci, E; Lastrucci, L; Paggiaro, PL; Pardi, F; Rossi, O; Talini, D	1
Broseghini, C; Di Giacomo, GR; Fabbri, LM; Mapp, CE; Omini, C	1
Boschetto, P; Burlina, A; Fabbri, LM; Licata, B; Mapp, CE; Milani, G; Pivirotto, F; Plebani, M; Zocca, E	1
Hargreave, FE; Pugsley, SO; Ramsdale, EH	1
Candura, F; Moscato, G	1
Campbell, TP; Fabbri, L; Karol, MH; Maestrelli, P; Mapp, CE; Saetta, M; Tollerud, DJ	1
Bacci, E; Bancalari, L; Carrara, M; Dente, FL; Di Franco, A; Giannini, D; Giuntini, C; Paggiaro, PL; Vagaggini, B	1
Cartier, A; Cloutier, Y; Ghezzo, H; Malo, JL; Vandenplas, O	1
Boscaro, M; De Marzo, N; Fabbri, LM; Maestrelli, P; Mapp, CE; Saetta, M	1
Biscaldi, G; Corsico, A; Dellabianca, A; Gherson, G; Moscato, G; Vinci, G	1
Bacci, E; Bancalari, L; Dente, FL; Di Franco, A; Gherson, G; Giannini, D; Giuntini, C; Moscato, G; Paggiaro, PL; Vagaggini, B	1
Nahm, DH; Park, HS	1
Fedan, JS; Frazer, DG; Huang, J; Millecchia, LL	1
Frossard, N; Kopferschmitt-Kubler, MC; Pauli, G; Rohde, G	1
Jung, K; Kang, K; Kim, H; Nahm, D; Park, H	1
Karol, MH; Lange, RW; Lemus, R; Luster, MI; Matheson, JM	1
Jung, JW; Kim, HA; Kim, SS; Kim, YK; Lee, SK; Nahm, DH; Park, HS	1
Bononi, I; Boschetto, P; Maestrelli, P; Mapp, CE; Milan, G; Padoan, M; Piola, C; Pozzato, V; Simoni, M; Zedda, L	1
Cunningham, AR; Hoet, PH; Mandervelt, C; Nemery, B; Vanhooren, HM; Vanoirbeek, JA; Xu, H	1
Ceuppens, JL; Hoet, PH; Nemery, B; Tarkowski, M; Vanoirbeek, JA; Verbeken, EK	1
Choi, JH; Lee, SK; Nahm, DH; Park, HS; Suh, CH; Suh, YJ	1
Ahn, SW; Choi, JH; Kim, SH; Kim, YS; Nahm, DH; Park, HS; Suh, CH	1
Chiung, YM; Kao, YY; Liu, PS	1
Hong, CS; Kim, CW; Kim, SH; Lee, KW; Nahm, DH; Oh, HB; Park, HS; Shin, ES	1
Ceuppens, J; De Vooght, V; Hoet, PH; Mercier, CM; Nemery, B; Tarkowski, M; Vanhooren, HM; Vanoirbeek, JA	1
Fujimura, M; Furusho, S; Kasahara, K; Kita, T; Myou, S; Nakao, S; Sato, S; Takehara, K; Yasui, M	1
De Vooght, V; Hoet, PH; Nawrot, TS; Nemery, B; Vanhooren, HM; Vanoirbeek, JA	1
Ahn, MH; An, SH; Jang, AS; Kwon, JH; Park, BJ; Park, CS; Park, JW; Rhim, T	1
De Vooght, V; Hoet, PH; Nemery, B; Synhaeve, N; Vanoirbeek, JA	1
De Vooght, V; Haenen, S; Hoet, PH; Nemery, B; Vanoirbeek, JA; Verbeken, E	2
Clynen, E; De Vooght, V; Haenen, S; Hoet, PH; Maes, E; Nemery, B; Schoofs, L; Vanoirbeek, JA	1
Bernstein, DI; Boulet, LP; Cartier, A; Gautrin, D; Ho, SM; Lummus, ZL; Ouyang, B; Ying, J	1
Carlier, V; De Vooght, V; Devos, FC; Haenen, S; Hoet, PH; Nemery, B; Vanoirbeek, JA; Verbeken, E	1

Trials

3 trial(s) available for toluene 2,4-diisocyanate and methacholine chloride

Article	Year
Ketotifen does not inhibit asthmatic reactions induced by toluene di-isocyanate in sensitized subjects. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1989, Volume: 19, Issue:2 Topics: Asthma; Cyanates; Double-Blind Method; Forced Expiratory Volume; Humans; Hypersensitivity, Delayed; Immunization; Ketotifen; Methacholine Chloride; Methacholine Compounds; Random Allocation; Toluene 2,4-Diisocyanate	1989
Protective effect of antiasthma drugs on late asthmatic reactions and increased airway responsiveness induced by toluene diisocyanate in sensitized subjects. The American review of respiratory disease, 1987, Volume: 136, Issue:6 Topics: Asthma; Beclomethasone; Bronchial Provocation Tests; Clinical Trials as Topic; Cromolyn Sodium; Cyanates; Delayed-Action Preparations; Double-Blind Method; Forced Expiratory Volume; Humans; Immunization; Lung; Methacholine Chloride; Methacholine Compounds; Placebos; Random Allocation; Respiratory System; Theophylline; Time Factors; Toluene 2,4-Diisocyanate; Verapamil	1987
Effects of inhaled beclomethasone on airway responsiveness in occupational asthma. Placebo-controlled study of subjects sensitized to toluene diisocyanate. The American review of respiratory disease, 1993, Volume: 148, Issue:2 Topics: Adolescent; Adult; Asthma; Beclomethasone; Bronchial Hyperreactivity; Bronchial Provocation Tests; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Hydrocortisone; Hypoglycemia; Insulin; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Placebos; Toluene 2,4-Diisocyanate	1993

Other Studies

44 other study(ies) available for toluene 2,4-diisocyanate and methacholine chloride

Article	Year
Isocyanate-induced asthma: results of inhalation tests with TDI, MDI and methacholine. International archives of occupational and environmental health, 1991, Volume: 63, Issue:1 Topics: Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Isocyanates; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Respiratory Function Tests; Skin Tests; Toluene 2,4-Diisocyanate	1991
Toluene diisocyanate-induced asthma: clinical findings and bronchial responsiveness studies in 113 exposed subjects with work-related respiratory symptoms. Journal of occupational medicine. : official publication of the Industrial Medical Association, 1991, Volume: 33, Issue:6 Topics: Adult; Asthma; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Occupational Diseases; Spirometry; Toluene 2,4-Diisocyanate; Vital Capacity	1991
Significant changes of bronchial responsiveness to methacholine after early asthmatic reaction to toluene diisocyanate (TDI) in a TDI-sensitive asthmatic worker. Journal of Korean medical science, 1990, Volume: 5, Issue:4 Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Humans; Male; Methacholine Chloride; Occupational Diseases; Skin Tests; Time Factors; Toluene 2,4-Diisocyanate	1990
Neutrophil chemotactic activity in toluene diisocyanate (TDI)-induced asthma. The Journal of allergy and clinical immunology, 1990, Volume: 85, Issue:3 Topics: Animals; Asthma; Basophils; Bronchial Provocation Tests; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Chromatography, Gel; Cyanates; Forced Expiratory Volume; Humans; Mast Cells; Methacholine Chloride; Methacholine Compounds; Mites; Molecular Weight; Neutrophils; Time Factors; Toluene 2,4-Diisocyanate	1990
Importance of airway inflammation for late asthmatic reactions induced by toluene diisocyanate in sensitized subjects. Advances in prostaglandin, thromboxane, and leukotriene research, 1987, Volume: 17B Topics: Adult; Asthma; Cyanates; Humans; Inflammation; Male; Methacholine Chloride; Methacholine Compounds; Respiratory System; Time Factors; Toluene 2,4-Diisocyanate	1987
Recurrent asthma induced by toluene diisocyanate. Thorax, 1988, Volume: 43, Issue:8 Topics: Adult; Asthma; Chemical Industry; Cyanates; Humans; Male; Methacholine Chloride; Methacholine Compounds; Occupational Diseases; Recurrence; Toluene 2,4-Diisocyanate	1988
Persistent asthma due to isocyanates. A follow-up study of subjects with occupational asthma due to toluene diisocyanate (TDI). The American review of respiratory disease, 1988, Volume: 137, Issue:6 Topics: Asthma; Bronchial Provocation Tests; Chronic Disease; Cyanates; Environmental Exposure; Female; Follow-Up Studies; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Methacholine Compounds; Toluene 2,4-Diisocyanate	1988
Combined asthma and alveolitis due to diphenylmethane diisocyanate (MDI) with demonstration of no crossed respiratory reactivity to toluene diisocyanate (TDI). Annals of allergy, 1985, Volume: 54, Issue:5 Topics: Adult; Alveolitis, Extrinsic Allergic; Asthma; Bronchi; Bronchial Provocation Tests; Cyanates; Female; Forced Expiratory Volume; Humans; Isocyanates; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Neutrophils; Therapeutic Irrigation; Toluene 2,4-Diisocyanate	1985
Prednisone inhibits late asthmatic reactions and the associated increase in airway responsiveness induced by toluene-diisocyanate in sensitized subjects. The American review of respiratory disease, 1985, Volume: 132, Issue:5 Topics: Adult; Asthma; Cyanates; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Prednisone; Respiratory System; Toluene 2,4-Diisocyanate	1985
Toluene diisocyanate-induced asthma without airway hyperresponsiveness. European journal of respiratory diseases, 1986, Volume: 68, Issue:2 Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Cyanates; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate	1986
Persistent airways disease caused by toluene diisocyanate. The American review of respiratory disease, 1986, Volume: 134, Issue:1 Topics: Asthma; Bronchial Provocation Tests; Cyanates; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Occupational Diseases; Time Factors; Toluene 2,4-Diisocyanate	1986
Specific bronchial reactivity to toluene diisocyanate: dose-response relationship. Respiration; international review of thoracic diseases, 1986, Volume: 50, Issue:3 Topics: Asthma; Bronchi; Bronchial Provocation Tests; Cyanates; Differential Threshold; Dose-Response Relationship, Drug; Forced Expiratory Volume; Humans; Methacholine Chloride; Methacholine Compounds; Toluene 2,4-Diisocyanate	1986
Late, but not early, asthmatic reactions induced by toluene-diisocyanate are associated with increased airway responsiveness to methacholine. European journal of respiratory diseases, 1986, Volume: 69, Issue:4 Topics: Adult; Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds; Occupational Diseases; Time Factors; Toluene 2,4-Diisocyanate	1986
Bronchoalveolar neutrophilia during late asthmatic reactions induced by toluene diisocyanate. The American review of respiratory disease, 1987, Volume: 136, Issue:1 Topics: Asthma; Bronchi; Bronchial Provocation Tests; Cyanates; Dose-Response Relationship, Drug; Eosinophils; Forced Expiratory Volume; Humans; Leukocyte Count; Methacholine Chloride; Methacholine Compounds; Neutrophils; Pulmonary Alveoli; Therapeutic Irrigation; Time Factors; Toluene 2,4-Diisocyanate	1987
Occupational asthma without bronchial hyperresponsiveness. The American review of respiratory disease, 1984, Volume: 130, Issue:3 Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Histamine; Humans; Male; Methacholine Chloride; Methacholine Compounds; Occupational Diseases; Peak Expiratory Flow Rate; Pulmonary Ventilation; Toluene 2,4-Diisocyanate	1984
Do amines induce occupational asthma in workers manufacturing polyurethane foams? British journal of industrial medicine, 1984, Volume: 41, Issue:4 Topics: Amines; Asthma; Chemical Industry; Humans; Methacholine Chloride; Methacholine Compounds; Occupational Diseases; Phenylenediamines; Polyurethanes; Toluene 2,4-Diisocyanate	1984
Predictive value of airways hyperresponsiveness and circulating IgE for identifying types of responses to toluene diisocyanate inhalation challenge. American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:3 Pt 1 Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chi-Square Distribution; Female; Forced Expiratory Volume; Humans; Immunoglobulin E; Immunoglobulin G; Male; Methacholine Chloride; Occupational Diseases; Predictive Value of Tests; Reproducibility of Results; Skin Tests; Toluene 2,4-Diisocyanate	1994
Bronchial hyperresponsiveness and toluene diisocyanate. Long-term change in sensitized asthmatic subjects. Chest, 1993, Volume: 103, Issue:4 Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Time Factors; Toluene 2,4-Diisocyanate	1993
Response to isocyanates: effect of concentration, duration of exposure, and dose. The American review of respiratory disease, 1993, Volume: 147, Issue:5 Topics: Adult; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Middle Aged; Toluene 2,4-Diisocyanate	1993
Bronchial responsiveness to ultrasonic fog in occupational asthma due to toluene diisocyanate. Chest, 1993, Volume: 104, Issue:4 Topics: Adult; Aerosols; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Humans; Male; Methacholine Chloride; Occupational Diseases; Sensitivity and Specificity; Toluene 2,4-Diisocyanate; Ultrasonics; Water	1993
Comparison between peak expiratory flow and forced expiratory volume in one second (FEV1) during bronchoconstriction induced by different stimuli. The Journal of asthma : official journal of the Association for the Care of Asthma, 1997, Volume: 34, Issue:2 Topics: Allergens; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Exercise Test; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Nebulizers and Vaporizers; Peak Expiratory Flow Rate; Regression Analysis; Sensitivity and Specificity; Toluene 2,4-Diisocyanate; Water	1997
Prognostic factors for toluene diisocyanate-induced occupational asthma after removal from exposure. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1997, Volume: 27, Issue:10 Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Environmental Exposure; Female; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Longitudinal Studies; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Prognosis; Smoking; Steroids; Toluene 2,4-Diisocyanate	1997
Brief exposure of air-filled guinea-pig isolated trachea to low levels of toluene diisocyanate (TDI) vapor in vitro increases reactivity to methacholine. Toxicology, 1997, Dec-26, Volume: 124, Issue:2 Topics: Air; Animals; Bronchoconstrictor Agents; Capsaicin; Dose-Response Relationship, Drug; Drug Interactions; Epithelium; Guinea Pigs; In Vitro Techniques; Male; Methacholine Chloride; Perfusion; Specific Pathogen-Free Organisms; Toluene 2,4-Diisocyanate; Trachea	1997
Increase in non-specific bronchial hyperresponsiveness without specific response to isocyanate in isocyanate-induced asthma: a pilot study. Respiratory medicine, 1998, Volume: 92, Issue:9 Topics: Adult; Air Pollutants, Occupational; Analysis of Variance; Asthma; Bronchial Hyperreactivity; Female; Humans; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Parasympathomimetics; Pilot Projects; Predictive Value of Tests; Statistics, Nonparametric; Toluene 2,4-Diisocyanate	1998
Neutrophil activation following TDI bronchial challenges to the airway secretion from subjects with TDI-induced asthma. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1999, Volume: 29, Issue:10 Topics: Adult; Asthma; Bronchi; Bronchoconstrictor Agents; Female; Humans; Interleukin-8; Male; Methacholine Chloride; Middle Aged; Neutrophil Activation; Occupational Diseases; Peroxidase; Sputum; Toluene 2,4-Diisocyanate	1999
Role of tumor necrosis factor in toluene diisocyanate asthma. American journal of respiratory cell and molecular biology, 2002, Volume: 27, Issue:4 Topics: Allergens; Animals; Antigens, CD; Asthma; B7-2 Antigen; Cytokines; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Immunoglobulin E; Immunoglobulin G; Interferon-gamma; Interleukin-4; Lymph Nodes; Membrane Glycoproteins; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Occupational Exposure; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleases; Time Factors; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha	2002
Metalloproteinase-9 is increased after toluene diisocyanate exposure in the induced sputum from patients with toluene diisocyanate-induced asthma. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2003, Volume: 33, Issue:1 Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstrictor Agents; Case-Control Studies; Female; Gelatinases; Humans; Irritants; Lung; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Methacholine Chloride; Middle Aged; Occupational Diseases; Sputum; Tissue Inhibitor of Metalloproteinase-1; Toluene 2,4-Diisocyanate	2003
Long-term follow-up of toluene diisocyanate-induced asthma. The European respiratory journal, 2003, Volume: 21, Issue:4 Topics: Adult; Asthma; Bronchial Provocation Tests; Female; Follow-Up Studies; Humans; Logistic Models; Longitudinal Studies; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Occupational Diseases; Occupational Exposure; Prognosis; Respiratory Function Tests; Toluene 2,4-Diisocyanate	2003
Validity of methods to predict the respiratory sensitizing potential of chemicals: A study with a piperidinyl chlorotriazine derivative that caused an outbreak of occupational asthma. Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 76, Issue:2 Topics: Adjuvants, Immunologic; Administration, Cutaneous; Allergens; Animals; Asthma; Bronchoalveolar Lavage; Dermatitis, Allergic Contact; Dose-Response Relationship, Drug; Female; Immunoglobulin E; Local Lymph Node Assay; Lung; Lymph Nodes; Methacholine Chloride; Mice; Mice, Inbred BALB C; Occupational Exposure; Oxazolone; Piperidines; Predictive Value of Tests; Structure-Activity Relationship; Toluene 2,4-Diisocyanate; Triazines	2003
Respiratory response to toluene diisocyanate depends on prior frequency and concentration of dermal sensitization in mice. Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 80, Issue:2 Topics: Administration, Intranasal; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Dermatitis, Allergic Contact; Disease Models, Animal; Immunoglobulin E; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Occupational Exposure; Plethysmography, Whole Body; Respiratory Mechanics; Toluene 2,4-Diisocyanate	2004
Acute and chronic changes of vascular endothelial growth factor (VEGF) in induced sputum of toluene diisocyanate (TDI)-induced asthma patients. Journal of Korean medical science, 2004, Volume: 19, Issue:3 Topics: Adult; Asthma; Bronchi; Enzyme-Linked Immunosorbent Assay; Exercise; Humans; Methacholine Chloride; Middle Aged; Placebos; Sputum; Time Factors; Toluene 2,4-Diisocyanate; Vascular Endothelial Growth Factor A	2004
Increased levels of IgG to cytokeratin 19 in sera of patients with toluene diisocyanate-induced asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2004, Volume: 93, Issue:3 Topics: Adult; Allergens; Antibody Specificity; Asthma; Autoantibodies; Autoantigens; Bronchi; Bronchial Provocation Tests; Cell Line, Transformed; Cells, Cultured; Coculture Techniques; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Female; Gene Expression Profiling; Humans; Immunoconjugates; Immunoglobulin E; Immunoglobulin G; Keratins; Male; Methacholine Chloride; Middle Aged; Oligonucleotide Array Sequence Analysis; RNA, Messenger; Serum Albumin; Toluene 2,4-Diisocyanate	2004
Effect of toluene diisocyanate on homeostasis of intracellular-free calcium in human neuroblastoma SH-SY5Y cells. Toxicology and applied pharmacology, 2006, Mar-01, Volume: 211, Issue:2 Topics: Atropine; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Signaling; Cell Line, Tumor; Cytosol; Dose-Response Relationship, Drug; Drug Synergism; Egtazic Acid; Endoplasmic Reticulum; Hexamethonium; Homeostasis; Humans; Intracellular Fluid; Ionomycin; Methacholine Chloride; Neuroblastoma; Potassium; Pyridines; Receptor, Muscarinic M3; Thapsigargin; Toluene 2,4-Diisocyanate; Verapamil	2006
HLA DRB115-DPB105 haplotype: a susceptible gene marker for isocyanate-induced occupational asthma? Allergy, 2006, Volume: 61, Issue:7 Topics: Adult; Asthma; Biomarkers; Bronchial Provocation Tests; Bronchoconstrictor Agents; Case-Control Studies; Female; Haplotypes; HLA-DP Antigens; HLA-DP beta-Chains; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Korea; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Occupational Exposure; Skin Tests; Toluene 2,4-Diisocyanate	2006
Immunological determinants of ventilatory changes induced in mice by dermal sensitization and respiratory challenge with toluene diisocyanate. American journal of physiology. Lung cellular and molecular physiology, 2007, Volume: 292, Issue:1 Topics: Airway Resistance; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Immunoglobulins; In Vitro Techniques; Lymphocytes; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, SCID; Skin; Toluene 2,4-Diisocyanate	2007
Role of intercellular adhesion molecule-1 in a murine model of toluene diisocyanate-induced asthma. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2006, Volume: 36, Issue:10 Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Chemokine CXCL2; Chemokines; Immunoglobulin E; Immunoglobulin G; Immunohistochemistry; Intercellular Adhesion Molecule-1; Interferon-gamma; Interleukin-4; Interleukin-5; Lung; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Occupational Diseases; Time Factors; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha	2006
How long do the systemic and ventilatory responses to toluene diisocyanate persist in dermally sensitized mice? The Journal of allergy and clinical immunology, 2008, Volume: 121, Issue:2 Topics: Administration, Intranasal; Animals; Body Weight; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Chemokine CXCL2; Ear, External; Immunization; Immunoglobulin E; Immunoglobulin G; Interferon-gamma; Interleukin-4; Lymph Nodes; Lymphocyte Subsets; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Neutrophils; Respiration; Respiratory Hypersensitivity; Skin; Time Factors; Toluene 2,4-Diisocyanate	2008
Asp-Tyr-Leu-Lys tetrapeptide inhibits airway inflammation in toluene-2,4-diisocyanate-induced asthma mice. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2008, Volume: 38, Issue:6 Topics: Actins; Animals; Asthma; Bronchi; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cattle; Cell Proliferation; Dose-Response Relationship, Drug; Down-Regulation; Endothelial Cells; Immunohistochemistry; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mucin 5AC; Mucins; Oligopeptides; Proliferating Cell Nuclear Antigen; Statistics, Nonparametric; Toluene 2,4-Diisocyanate; Trachea; Vascular Endothelial Growth Factor A	2008
Is toluene diamine a sensitizer and is there cross-reactivity between toluene diamine and toluene diisocyanate? Toxicological sciences : an official journal of the Society of Toxicology, 2009, Volume: 109, Issue:2 Topics: Animals; Antigens, CD; Asthma; Cells, Cultured; Cross Reactions; Cytokines; Disease Models, Animal; Immunoglobulins; Local Lymph Node Assay; Lymphocytes; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Phenylenediamines; Statistics, Nonparametric; Toluene 2,4-Diisocyanate	2009
Oropharyngeal aspiration: an alternative route for challenging in a mouse model of chemical-induced asthma. Toxicology, 2009, May-02, Volume: 259, Issue:1-2 Topics: Administration, Intranasal; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cytokines; Disease Models, Animal; Eosinophils; Immunoglobulin E; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Neutrophils; Respiratory Aspiration; Toluene 2,4-Diisocyanate; Up-Regulation	2009
Proteome analysis of multiple compartments in a mouse model of chemical-induced asthma. Journal of proteome research, 2010, Nov-05, Volume: 9, Issue:11 Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Inflammation; Mass Spectrometry; Methacholine Chloride; Mice; Neutrophils; Oxidative Stress; Proteome; Toluene 2,4-Diisocyanate	2010
Successful transfer of chemical-induced asthma by adoptive transfer of low amounts of lymphocytes in a mouse model. Toxicology, 2011, Jan-11, Volume: 279, Issue:1-3 Topics: Adoptive Transfer; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Disease Models, Animal; Immunoglobulin E; Lymphocytes; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Neutrophils; Time Factors; Toluene 2,4-Diisocyanate	2011
Interferon-γ promoter is hypermethylated in blood DNA from workers with confirmed diisocyanate asthma. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 133, Issue:2 Topics: Adult; Asthma; DNA; DNA Methylation; Epigenesis, Genetic; Female; Humans; Interferon-gamma; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Occupational Exposure; Promoter Regions, Genetic; Sensitivity and Specificity; Toluene 2,4-Diisocyanate; Young Adult	2013
B-lymphocytes as key players in chemical-induced asthma. PloS one, 2013, Volume: 8, Issue:12 Topics: Animals; Asthma; B-Lymphocyte Subsets; B7-1 Antigen; B7-2 Antigen; Bronchoconstrictor Agents; CD40 Antigens; Disease Models, Animal; Immunoglobulin E; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Knockout; Mice, SCID; Toluene 2,4-Diisocyanate	2013