toluene 2,4-diisocyanate has been researched along with cyanates in 337 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 246 (73.00) | 18.7374 |
| 1990's | 36 (10.68) | 18.2507 |
| 2000's | 27 (8.01) | 29.6817 |
| 2010's | 19 (5.64) | 24.3611 |
| 2020's | 9 (2.67) | 2.80 |
| Authors | Studies |
|---|---|
| Battigelli, MC; Vanert, M | 1 |
| Butcher, BT; Garg, O; O'Neil, CE; Salvaggio, JE; Weill, H | 1 |
| Butcher, BT; Dharmarajan, V; Diem, JE; Glindmeyer, HW; Jones, RN; O'Neil, CE; Salvaggio, JE; Weill, H | 1 |
| Adams, WG; Carney, IF; Chamberlain, JD; Paddle, GM | 1 |
| Burge, PS; Harries, MG; O'Brien, I; Taylor, AJ | 1 |
| Peters, JM; Wegman, DH | 2 |
| Adams, WG | 1 |
| Higgins, RL; Porter, CV; Scheel, LD | 1 |
| Booth, KS; Neilson, A | 1 |
| Henderson, R; Smith, DB | 1 |
| Butcher, B; Neilson, A; Salvaggio, J; Weill, H; Ziskind, M | 1 |
| Aresini, G; Cirla, A; Sala, C; Zedda, S | 1 |
| Nekhorotseva, EV; Simonov, VA; Zavorovskaia, NA | 1 |
| Dahl, R; Zetterström, O | 1 |
| Lachnit, V | 1 |
| Axford, AT; Jones, AP; Le Quesne, PM; McKerrow, CB | 2 |
| Carroll, KB; Pepys, J; Secombe, CJ | 1 |
| Alanko, K; Häkkinen, I; Vaaranen, IH | 1 |
| Butcher, BT; Salvaggio, JE; Weill, H; Ziskind, MM | 1 |
| Bernstein, A; Charles, J; Edwards, JH; Jones, B; Jones, DJ; Seal, RM; Seaton, A | 1 |
| McFadyen, P | 1 |
| Lotti, M; Manno, M | 1 |
| Kryshanovskaia, NA; Sharonova, ZV | 1 |
| Salvadori, P; Scrima, M | 1 |
| Holland, DG; Rooney, TA | 1 |
| Swarbrick, KP | 1 |
| Butcher, BT; Davies, RJ; O'Neil, CE; Salvaggio, JE | 1 |
| Fine, LJ; Pagnotto, L; Peters, JM; Wegman, DH | 1 |
| Dharmarajan, V | 1 |
| Copeland, RL; Mahan, DE | 1 |
| Abbritti, G; Curradi, F; Siracusa, A | 1 |
| Hardy, HL; Purnell, CJ | 1 |
| Katz, M | 1 |
| Alarie, YC; Karol, MH | 1 |
| Dharmarajan, V; Self, CW; Weil, H | 1 |
| Alarie, YC; Ioset, HH; Karol, MH | 1 |
| Okada, A; Yamada, Y | 1 |
| Cirla, AM; Sala, C; Zedda, S | 1 |
| Chester, EH; Fleming, GM; Gerblich, AA; Horowitz, JG; Schwartz, HJ | 1 |
| Burge, PS; Harries, MG; O'Brien, IM; Pepys, J | 1 |
| Burge, PS; Fawcett, IW; Harries, MG; Newman-Taylor, AJ; O'Brien, IM; Pepys, J | 1 |
| Brethauer, R; Chester, EH; Fleming, GM; Gerblich, AA; Horowitz, J; Martinez-Catinchi, FL; McDonald, EW; Schwartz, HJ | 1 |
| Hopkins, J | 2 |
| Butcher, BT; Dharmarajan, V; Karr, RM; O'Neil, CE; Salvaggio, JE; Weill, H; Wilson, MR | 1 |
| Alarie, Y; Karol, MH; Riley, EJ; Sandberg, T | 1 |
| Burge, PS; Harries, MG; O'Brien, IM | 1 |
| Lubach, D | 2 |
| Kunilova, LV; Lipina, TG; Tubina, AIa | 1 |
| Bernstein, IL; Chen, SE; Tse, CS | 1 |
| Butcher, BT | 4 |
| Chester, EH; Fleming, GM; Gerblich, AA; Horowitz, J; Schwartz, HJ | 1 |
| Alarie, Y; Sangha, GK | 1 |
| Tanaka, K | 2 |
| Pesce, AJ; Tse, CS | 1 |
| Dharmarajan, V; Rando, RJ | 3 |
| Baur, X; Fruhmann, G; Römmelt, H | 1 |
| Alarie, Y; Karol, MH; Riley, EJ | 1 |
| Fink, JN; Schlueter, DP | 1 |
| Akimoto, T; Dambara, T; Kira, S; Nukiwa, T; Tamura, N; Uchida, K | 1 |
| Arai, Y; Fukushima, N; Hosojima, T; Matsuzaki, G; Miyamoto, Y; Sano, Y; Suko, M; Suzuki, N | 1 |
| Karol, MH | 4 |
| Baur, X; Fruhmann, G; Vogelmeier, C | 1 |
| Baj, A; Nano, G; Sesana, G | 1 |
| Fabbri, LM | 2 |
| Banks, DE; Barkman, HW; Rando, RJ | 1 |
| Eberle, ME; Harris, KE; Nugent, KM; Patterson, R | 1 |
| Allegra, L; Calabrò, F; Masiero, M; Mattoli, S; Mezzetti, M; Plebani, M | 1 |
| Bernard, J; Cazabat, A; Kochman, S; Lavaud, F; Lefebvre, S; Manfait, M; Maujean, A | 1 |
| Banks, DE; Barkman, HW; Lopez, M; Salvaggio, JE; Sastre, J | 1 |
| Fischbein, A; Luo, JC; Nelsen, KG | 1 |
| Boschetto, P; Fabbri, LM; Mapp, CE; Masiero, M; Milani, GF; Pivirotto, F; Plebani, M; Zocca, E | 1 |
| Chitano, P; Fabbri, LM; Geppetti, P; Maggi, CA; Mapp, CE; Patacchini, R; Santicioli, P | 1 |
| Cartier, A; Grammer, LC; Harris, KE; Malo, JL; Patterson, R | 1 |
| Alegre, J; Cobo, E; Morell, F | 1 |
| Bacci, E; Bernard, P; Dente, FL; Giuntini, C; Marchetti, G; Menconi, GF; Paggiaro, P; Paoletti, P; Talini, D | 1 |
| Lee, HS; Phoon, WH; Poh, SC; Wang, YT | 1 |
| Fujii, T; Misumi, S; Onoda, K; Takeda, F | 1 |
| Gordon, T; Scypinski, LA; Sheppard, D; Thompson, JE | 1 |
| Borson, DB; Dusser, D; Nadel, JA; Scypinski, L; Sheppard, D; Thompson, JE | 1 |
| Scypinski, L; Sheppard, D | 1 |
| Hasegawa, S; Noguchi, K; Ohtsuka, M; Suko, M; Uchida, Y; Yoshizawa, Y | 1 |
| Belin, L; Wass, U | 1 |
| Bast, A; Borm, PJ; Zuiderveld, OP | 1 |
| Chang, SN; Hammad, YY; Rando, RJ | 2 |
| Kristol, DS; Rao, G; Stackhouse, JA; Von Hagen, S | 1 |
| Liapun, IV; Maslo, LL; Putilina, ON | 1 |
| Dahl, R; Rasmussen, K | 1 |
| Chiesura-Corona, P; Crescioli, S; De Marzo, N; Fabbri, LM; Mapp, CE; Picotti, G; Tossin, L | 1 |
| Bodner, KM; Bond, GG; Emmitte, JA; Flores, GH; Olsen, GW; Saunders, JH; Shellenberger, R | 1 |
| Alarie, Y; Brown, WE; Kennedy, AL; Stock, MF | 1 |
| Corona, PC; Crescioli, S; De Marzo, N; Fabbri, LM; Leproux, GB; Mapp, CE; Tossin, L | 1 |
| Grammer, L | 1 |
| Duan, YY | 1 |
| Brorson, T; Renman, L; Sangö, C; Skarping, G | 1 |
| Arakawa, M; Kioi, S; Nozawa, S; Sasagawa, M; Sato, T; Suzuki, E | 1 |
| Dukhovnaia, IS; Iun, EM; Reva, IuP | 1 |
| Boschetto, P; Bruchi, O; Cappellazzo, G; Fabbri, LM; Mapp, CE; Milani, GF; Pivirotto, F; Zocca, E | 1 |
| Bacci, E; Dente, FL; Fabbri, LM; Giuntini, C; Paggiaro, P; Pulerá, N; Rossi, O; Talini, D | 1 |
| Boschetto, P; Crescioli, S; dal Vecchio, L; de Marzo, N; Fabbri, LM; Mapp, C; Paleari, D | 1 |
| Hanada, S; Nishimura, F; Takeoka, A; Tanaka, K | 1 |
| Dziedziczko, A; Sieradzki, E; Wichtowski, W | 1 |
| Hanada, S; Kawai, M; Kohno, S; Nagaya, Y; Nishimura, F; Okamoto, Y; Takeoka, A; Tanaka, K | 1 |
| Dalene, M; Mathiasson, L; Sandström, JF; Sangö, C; Skarping, G | 1 |
| Botham, PA; Hext, PM; Rattray, NJ; Walsh, ST; Woodcock, DR | 1 |
| Nagao, N | 2 |
| Brooks, SM; Cibulas, W; McKay, RT; Miller, ML; Murlas, CG | 1 |
| Dukhovnaia, IS; Iun, EM | 1 |
| Huang, PH; Lin, JM; Su, SY; Wang, JD; Wu, MC | 1 |
| Cirla, AM; Innocenti, A; Mariano, A; Pisati, G | 1 |
| Diller, W | 1 |
| Banks, DE; Rando, RJ | 1 |
| Corona, PC; De Marzo, N; Fabbri, L; Mapp, CE | 1 |
| Bevilacqua, P; Crescioli, S; Danieli, D; Fabbri, LM; Mapp, CE; Meli, S; Saetta, M | 1 |
| Boll, KL; Eriksen, J | 1 |
| Bonnet, P; de Ceaurriz, J; Gagnaire, F; Micillino, JC; Simon, P | 1 |
| Fiorini, R; Governa, M; Valentino, M | 1 |
| Keskinen, H; Nordman, H; Tiikkainen, U; Tupasela, O | 1 |
| Ermakova, GA; Kryzhanovskaia, NA | 1 |
| Gee, JB; Morgan, WK | 1 |
| Baschieri, L; Lastrucci, L; Paggiaro, PL; Pardi, F; Pezzini, A; Rossi, O | 1 |
| Alarie, Y; Karol, MH; Wong, KL | 1 |
| Alexandersson, R; Hedenstierna, G; Randma, E; Rosen, G; Swenson, A; Tornling, G | 1 |
| Fabbri, LM; Hendrick, DJ; Maestrelli, P; Mapp, CE; Polato, R | 1 |
| Boschetto, P; Dal Vecchio, L; Fabbri, LM; Mapp, CE | 1 |
| Rosenberg, C; Savolainen, H | 3 |
| Hammad, YY; Rando, RJ | 1 |
| Kay, S | 1 |
| Burge, PS; Dally, MB; Newman Taylor, AJ; Pickering, CA; Venables, KM | 1 |
| Hanada, S; Ino, T; Kohno, S; Okamoto, Y; Okuizumi, J; Takeoka, A; Tanaka, K | 1 |
| Lange, P; Schaffernicht, H | 1 |
| Liu, JY | 1 |
| Purnell, CJ; Walker, RF | 1 |
| Chiesura-Corona, P; Dal Vecchio, L; de Marzo, N; di Giacomo, GR; Fabbri, LM; Maestrelli, P; Mapp, CE; Zocca, E | 1 |
| Distefano, S; Gordon, T; McDonald, DM; Scypinski, L; Sheppard, D | 1 |
| Berstein, L; Musk, AW; Peters, JM | 1 |
| Kohno, S; Ohata, K; Tanaka, K; Tominaga, M | 1 |
| Dzhogan, IM | 1 |
| Hanada, S; Marui, S; Nagaya, Y; Okamoto, Y; Tanaka, K | 1 |
| Boschetto, P; Dal Vecchio, L; De Marzo, N; Fabbri, LM; Mapp, CE | 1 |
| Bernstein, IL; Brooks, SM; Cibulas, W; McKay, RT; Miller, ML; Murlas, CG; Schmidt, DJ; Vinegar, A | 1 |
| Bernstein, IL; Brooks, SM; McKay, RT; Moller, DR | 1 |
| Bacci, E; Innocenti, A; Paggiaro, PL; Rossi, O; Talini, D | 1 |
| Dharmarajan, V; Hackathorn, DR; Lingg, RD | 1 |
| Bernstein, IL; Brooks, SM; Cassedy, K; Kopp, S; McKay, RT; Moller, DR | 1 |
| Adams, WD; Andringa, A; Brooks, SM; Cibulas, W; Miller, ML; Vinegar, A | 1 |
| Ito, T; Kudo, T; Miki, T; Shima, S; Tachikawa, S; Yoshida, T | 1 |
| Baur, X; Mazur, G; Pfaller, A; Römmelt, H | 1 |
| Banks, DE; Butcher, BT; Salvaggio, JE | 1 |
| Bacci, E; Lastrucci, L; Paggiaro, PL; Pardi, F; Rossi, O; Talini, D | 1 |
| Reynolds, JA | 1 |
| Broseghini, C; Di Giacomo, GR; Fabbri, LM; Mapp, CE; Omini, C | 1 |
| Comai, M; Governa, M; Rocco, M; Ruschioni, A; Valentino, M | 1 |
| Mäki-Paakkanen, J; Norppa, H | 1 |
| Boschetto, P; Burlina, A; Fabbri, LM; Licata, B; Mapp, CE; Milani, G; Pivirotto, F; Plebani, M; Zocca, E | 1 |
| Ermakova, GA; Kryzhanovskaia, NA; Liuro, SD; Sharonova, ZV; Volkova, ID | 1 |
| Abdel-Kader, H; Duvoisin, PF; Hammad, YY; Rando, RJ | 1 |
| Abdel-Kader, H; Hammad, YY; Hughes, J; Rando, RJ | 1 |
| Dolovich, J; Grammer, LC; Hargreave, FE; Harris, KE; Patterson, R | 1 |
| Boschetto, P; Dal Vecchio, A; Fabbri, LM; Mapp, CE; Milani, G; Pivirotto, F; Plebani, M; Zocca, E | 1 |
| Hosoda, H; Ito, T; Kato, Y; Miki, T; Nagaoka, K; Shima, S; Tachikawa, S; Taniwaki, H; Yoshida, T; Yuri, T | 1 |
| Filieri, M; Gerosa, F; Paggiaro, P; Pezzini, A; Riviera, A; Spiazzi, A; Toma, G; Tridente, G | 1 |
| Baschieri, L; Ferrante, B; Loi, AM; Paggiaro, PL; Pardi, F; Roselli, MG; Rossi, O | 1 |
| Fujimura, N; Izumi, T; Kino, T; Kitaichi, M; Nagai, S; Ogawa, S; Oshima, S; Sato, K | 1 |
| Omae, K | 1 |
| Biscaldi, G; Candura, F; Gherson, G; Moscato, G | 1 |
| Biscaldi, G; Candura, F; Cottica, D; Moscato, G | 1 |
| Morris, MJ; Sugden, E; White, WG; Zapata, E | 1 |
| Boyd, ND; Chan, EK | 1 |
| Kido, T; Teranishi, H; Yamada, Y | 1 |
| Ino, T; Kawai, M; Maekawa, N; Ohata, K; Okamoto, Y; Takeoka, A; Tanaka, K; Watanabe-Kohno, S | 1 |
| Antonucci, JM; Brauer, GM; Termini, DJ | 1 |
| Alarie, Y; Karol, MH | 2 |
| Bellone, JD; Kanellakes, TM; Levitz, D; Patterson, R; Pruzansky, JJ; Zeiss, CR | 1 |
| Bernstein, IL; Blanchard, J; Brooks, SM; Gallagher, J; Smith, AB | 1 |
| Alarie, Y; Brady, M; Dixon, C; Karol, MH | 1 |
| Citri, N; Klemes, Y | 1 |
| Oleru, UG | 2 |
| Butcher, BT; O'Neil, CE; Reed, MA; Salvaggio, JE | 2 |
| Check, WA | 1 |
| Goto, T; Ishizu, S; Nozawa, G; Sasaki, N; Yasuda, K | 1 |
| Ebell, GF; Fleming, DE; Genovese, JH; Taylor, GA | 1 |
| Kielar, R; Luckenbach, M | 1 |
| Cooper, P | 1 |
| Alt, E; Baur, X; Diller, W; Fruhmann, G | 1 |
| Baur, X; Diller, W; Dorsch, W; Fruhmann, G; Römmelt, H; Roth, P | 1 |
| Buckingham, JA; Cromwell, O; Danks, JM; Davies, RJ; Newman-Taylor, AJ | 1 |
| Sepúlveda, R | 1 |
| Hauth, BA; Karol, MH; Magreni, CM; Riley, EJ | 1 |
| Brooks, SM; Johnson, C; McKay, RT | 1 |
| Baur, X; Fruhmann, G | 1 |
| Bernstein, IL; Brooks, SM; Gallagher, JS; Tse, CS | 1 |
| Dorofeeva, ED; Kryzhanovskaia, NA; Mel'nikova, ND; Penkovich, AA; Sharonova, ZV | 1 |
| Woolrich, PF | 1 |
| Bachmann, K; Forney, RB; Shapiro, R | 1 |
| Hurst, DJ | 1 |
| Alarie, YC; Brown, WE; Green, AH; Karol, MH | 1 |
| Doe, JE; Hicks, R; Milburn, GM | 1 |
| Bernstein, IL | 1 |
| Butcher, BT; O'Neil, CE; Reed, MA; Salvaggio, JE; Weill, H | 1 |
| Baur, X; Dewair, MA | 1 |
| Butcher, BT; Dharmarajan, V; Diem, JE; Glindmeyer, HW; Hendrick, DJ; Jones, RN; Salvaggio, JE; Weill, H | 1 |
| Bernstein, IL; Chen, SE | 1 |
| Bernstein, IL; Chen, SE; Splansky, GL; Vinegar, A | 1 |
| Andersen, M; Binderup, M; Kiel, P; Larsen, H; Maxild, J | 1 |
| Alarie, Y; Rodney, BS; Weyel, DA | 1 |
| Main, DM; Musk, AW; Pagnotto, LD; Wegman, DH | 1 |
| Burg, WR; Chang, SN | 1 |
| DiBerardinis, L; Murphy, RL; Musk, AW; Peters, JM | 1 |
| Kawai, M; Maekawa, N; Tanaka, K | 2 |
| Baur, X | 1 |
| Sandridge, RL | 1 |
| Burge, PS | 1 |
| Baschieri, L; Cantalupi, R; Filieri, M; Loi, AM; Paggiaro, PL; Parlanti, A; Roselli, MG; Toma, G | 1 |
| Loeser, E | 1 |
| Brunkhorst, CS; Burden, EJ; Friedman, MA; Koschier, FJ | 1 |
| Ayers, TA; Bishop, RW; Esposito, GG | 1 |
| Wang, SR; Wang, SS | 1 |
| Harris, KE; Patterson, R; Zeiss, CR | 2 |
| Brooks, SM; McKay, RT | 2 |
| Eisen, EA; Greaves, IA; Robins, J | 1 |
| Daimon, N; Kido, T; Shimizu, T; Teranishi, H; Yamada, Y | 1 |
| Nagai, F; Saito, T | 1 |
| Baur, X; Dewair, M; Mauermayer, R | 1 |
| Higashihara, E; Hobara, T; Iwamoto, S; Kawamoto, T; Kobayashi, H; Sakai, T; Shimazu, W | 1 |
| Huff, JE | 1 |
| Abdel-Kader, HM; Hammad, YY; Rando, RJ | 1 |
| Ermakova, GA; Kryzhanovskaia, NA; Liuro, SD | 1 |
| Booth, N; Broder, I; Corey, PN; Guirguis, S; Holness, DL; Mozzon, D; Nazar, MA | 1 |
| Bernstein, DI; Herd, ZL | 1 |
| Baur, X; Marczynski, B; Marek, W; Potthast, J; Voss, B; Wiethege, T | 1 |
| Arnold, JE; Cooper, CV; Fischbach, TJ; Streicher, RP | 1 |
| Blaikie, L; Botham, PA; Hartop, PJ; Hext, P; Morrow, T; Rattray, NJ; Wilson, AP; Woodcock, D | 1 |
| Braatz, JA | 1 |
| Calcagni, PG; Di Stefano, A; Fabbri, LM; Hosselet, JJ; Maestrelli, P; Mapp, CE; Saetta, M; Santonastaso, A | 1 |
| Hagmar, L; Mikoczy, Z; Strömberg, U; Welinder, H | 1 |
| Baur, X; Czuppon, AB; Hartmann, R; Marczynski, B; Scheer, E | 1 |
| Hagmar, L; Mikoczy, Z; Welinder, H | 1 |
| Boukortt, S; Buchet, JP; Carbonnelle, P; Lison, D | 1 |
| Karol, MH; Kramarik, JA | 1 |
| Baur, X; Marczynski, B; Peel, M | 1 |
| Alam, R; Bernstein, DI; Bernstein, JA; Lummus, ZL | 1 |
| Herbold, B; Kopp, R; Seel, K; Walber, U | 1 |
| Bousková, S; Mráz, J | 1 |
| Baur, X; Marczynski, B; Marek, W; Mensing, T; Potthast, J | 1 |
| Aul, DJ; Bhaumik, A; Brown, WE; Kennedy, AL; Lesage, J; Malo, JL | 1 |
| Choi, IS; Jang, AS; Koh, YI; Lee, KJ; Moon, JD | 1 |
| Keskinen, HM; Luukkonen, R; Nordman, H; Piirilä, PL; Salo, SP; Tuomi, TO; Tuppurainen, M | 1 |
| Bugler, J; Clark, RL; Meredith, SK | 1 |
| Estlander, T; Jolanki, R; Kanerva, L; Keskinen, H | 1 |
| Beckett, PN; Curran, AD; Elms, J; Griffin, P | 1 |
| Hayashi, M; Higashi, K; Kaneko, H; Kato, H | 1 |
| Baur, X; Bolognesi, C; Marczynski, B; Norppa, H; Sabbioni, G; Sepai, O | 1 |
| Asanuma, H; Hishiya, T; Komiyama, M | 1 |
| Redlich, CA; Wisnewski, AV | 1 |
| Gordon, T; Redlich, CA; Wisnewski, AV | 1 |
| Bailey, RE; Pemberton, D; Tury, B | 1 |
| Cuesta, J; De Las Heras, M; Fernández-Nieto, M; Novalbos, A; Quirce, S; Sastre, J | 1 |
| Colmsjö, A; Johansson, R; Karlsson, D; Låstbom, L; Melin, J; Nordqvist, Y; Skarping, G | 1 |
| Liu, Q; Wisnewski, AV | 1 |
| BOFFARDI, G; JAMES, KE; LUNDY, W; SANDS, FW; WALSH, WS | 1 |
| VIRCHOW, WE; WALWORTH, HT | 1 |
| ASSMANN, W; HENSCHLER, D; MEYER, KO | 1 |
| GOWER, ND; JENNINGS, GH | 1 |
| SILVER, HM | 1 |
| MAXON, FC | 1 |
| RUTGERS, VH | 1 |
| Bailey, RE; Pemberton, D; Reimann, KA; Sendijarevic, A; Sendijarevic, I; Sendijarevic, V | 1 |
| Cloutier, Y; Gagne, S; Lesage, J; Ostiguy, C; Van Tra, H | 1 |
| Bracht, A; Brüning, T; Haufs, MG; Käfferlein, HU; Kappler, M; Marczynski, B; Mensing, T; Merget, R; Rabstein, S | 1 |
| Bousová, K; Krcmová, I | 1 |
| Krone, CA | 1 |
| Bruze, M; Frick-Engfeldt, M; Isaksson, M; Karlsson, D; Marand, A; Skarping, G; Zimerson, E | 1 |
| Bernstein, DI; Graham, C; Lummus, Z; Ott, MG; Woolhiser, M | 1 |
| Briançon, S; Fessi, H; Montasser, I | 1 |
| Axmon, A; Broberg, K; Littorin, M; Sennbro, CJ; Tinnerberg, H | 1 |
| Batlle, R; Crescenzi, C; López, P; Nerín, C | 1 |
| Lammintausta, K; Liippo, J | 1 |
| Bobeldijk, I; Gonsalves, J; Heederik, D; Hekman, M; Karlsson, D; Preller, L; Pronk, A; Skarping, G; Van De Lagemaat, D | 1 |
| Bucht, A; Gustafsson, A; Koch, BL; Svensson-Elfsmark, L | 1 |
| Beezhold, D; Johnson, VJ; Ruwona, TB; Schmechel, D; Siegel, PD; Simoyi, RH | 1 |
| Ehnes, C; Fabian, E; Gamer, A; Hoffmann, HD; Landsiedel, R; Leibold, E; Poole, A | 1 |
| Ahonen, N; Järvelä, M; Järventaus, H; Korpi, A; Lindberg, HK; Norppa, H; Pasanen, AL; Rosenberg, C; Säkkinen, K; Santonen, T; Tornaeus, J | 1 |
| Gu, Q; Sabbioni, G; Vanimireddy, LR | 1 |
| Choi, GS; Hur, GY; Kim, JH; Kim, SH; Nam, YH; Park, HS; Park, SM | 1 |
| Aalto-Korte, K; Henriks-Eckerman, ML; Jolanki, R; Kuuliala, O; Suuronen, K | 1 |
| Bernstein, DI; Boulet, LP; Cartier, A; Cruz, MJ; Fluharty, K; Gautrin, D; Germolec, DR; Johnson, VJ; Kissling, GE; Lummus, ZL; Luster, MI; Malo, JL; Munoz, X; Quirce, S; Sastre, J; Tarlo, SM; Yucesoy, B | 1 |
| Brzeźnicki, S; Czerczak, S; Kupczewska-Dobecka, M | 1 |
| Broberg, K; Jönsson, BA; Lindh, CH; Tinnerberg, H | 1 |
| Beezhold, DH; Bledsoe, TA; Green, BJ; Lemons, AR; Siegel, PD | 1 |
| Carson, M; Collins, MA; Hughes, MA; Jolly, AT; Molenaar, DM; Steffens, W; Swaen, GM | 1 |
| Jan, YD; Lee, BS; Lin, CP; Tseng, WY | 1 |
| Barszczewska-Rybarek, IM | 1 |
| Adriaensens, P; D'Haen, J; D'Olieslaeger, L; Ethirajan, A; Junkers, T; Kuypers, S; Peters, M; Pramanik, SK; Reekmans, G; Vanderzande, D | 1 |
| De Vooght, V; Devos, F; Hoet, PH; Nemery, B; Pollaris, L; Seys, S; Vanoirbeek, JA | 1 |
| Beezhold, DH; Bledsoe, TA; Chipinda, I; Green, BJ; Hettick, JM; Law, BF; Lemons, AR; Mhike, M; Nayak, AP; Siegel, PD; Simoyi, RH | 1 |
| Choi, WS; Choi, Y; Hong, KH; Kim, JH; Lee, WY; Park, C; Park, HJ; Song, H | 1 |
| Abushammala, H; Mao, J | 1 |
| Pauluhn, J | 1 |
| Aubin, S; Breau, L; Donchenko, A; Gagné, S; Lesage, J; Spence, M | 1 |
| Liu, J; Wisnewski, AV | 1 |
| Plehiers, PM; Schupp, T | 1 |
| Burleson, S; Chappelle, AH; Graham, C; Gulledge, T; Krieger, S; Miller, JW; Plehiers, PM; Simon, G; Snyder, S; West, RJ | 1 |
| Breau, L; Cloutier, PL; Daoud, A; Gagné, S; Lesage, J | 1 |
| Aerts, O; Dendooven, E; Foubert, K; Lambert, J; Naessens, T; Pieters, L | 1 |
| Chaudhary, PP; D'Souza, BN; Ganesan, S; Myles, IA; Ratley, G; Spathies, J; Yadav, M; Zeldin, J | 1 |
| Jones, K; Portengen, L; Pronk, A; Santonen, T; Scholten, B; Stierum, R; Vermeulen, R; Vlaanderen, J; Westerhout, J | 1 |
| Karlsson, D | 1 |
14 review(s) available for toluene 2,4-diisocyanate and cyanates
| Article | Year |
|---|---|
[The problem of isocyanates in industry. From pathology to control of the risk].
Topics: Air Pollutants; Air Pollutants, Occupational; Asthma; Bronchitis; Cough; Cyanates; Humans; Industry; Lung Diseases; Occupational Diseases; Polyurethanes; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 1978 |
2,4- and 2,6-toluene diisocyanates, 1,5-naphthalene diisocyanate, 4,4-methylenediphenyl diisocyanate and polymethylene polyphenyl isocyanate and flexible and rigid polyurethane foams.
Topics: Animals; Benzhydryl Compounds; Carcinogens; Chemical Phenomena; Chemistry; Cricetinae; Cyanates; Drug Implants; Humans; Industry; Lethal Dose 50; Male; Naphthalenes; Polyurethanes; Rats; Toluene 2,4-Diisocyanate | 1979 |
[A case of hypersensitivity pneumonitis due to isocyanate (TDI)].
Topics: Alveolitis, Extrinsic Allergic; Cyanates; Humans; Infusions, Intravenous; Isocyanates; Male; Methylprednisolone; Middle Aged; Occupational Diseases; Skin Tests; Toluene 2,4-Diisocyanate | 1989 |
Methods for the determination of atmospheric organic isocyanates. A review.
Topics: Air Pollutants; Chromatography, Gas; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Colorimetry; Cyanates; Humans; Isocyanates; Occupational Diseases; Spectrophotometry, Infrared; Toluene 2,4-Diisocyanate | 1985 |
Isocyanate-induced respiratory disease.
Topics: Asthma; Cyanates; Drug Hypersensitivity; Humans; Isocyanates; Occupational Diseases; Respiratory Hypersensitivity; Respiratory System; Toluene 2,4-Diisocyanate | 1986 |
Toxicology, industrial hygiene and medical control of TDI, MDI and PMPPI.
Topics: Animals; Chemical Phenomena; Chemistry; Cyanates; Humans; Isocyanates; Maximum Allowable Concentration; Occupational Diseases; Polymers; Toluene 2,4-Diisocyanate | 1982 |
Isocyanate-induced pulmonary diseases: a current perspective.
Topics: Animals; Asthma; Cyanates; Humans; Lung Diseases; Occupational Diseases; Occupational Health Services; Toluene 2,4-Diisocyanate | 1982 |
Carcinogenic risk of toluene diisocyanate and 4,4'-methylenediphenyl diisocyanate: epidemiological and experimental evidence.
Topics: Animals; Blood Proteins; Carcinogenicity Tests; Carcinogens; Chemical Industry; DNA Adducts; Female; Humans; Isocyanates; Male; Mutagenicity Tests; Neoplasms; Occupational Exposure; Protein Binding; Salmonella typhimurium; Toluene 2,4-Diisocyanate | 2001 |
Recent developments in diisocyanate asthma.
Topics: Asthma; Cyanates; Genes, MHC Class II; Genetic Predisposition to Disease; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Skin; T-Lymphocytes, Helper-Inducer; Toluene 2,4-Diisocyanate | 2001 |
Mouse models of diisocyanate asthma.
Topics: Allergens; Animals; Asthma; Cyanates; Disease Models, Animal; Isocyanates; Mice; Models, Biological; Models, Chemical; Toluene 2,4-Diisocyanate | 2002 |
Recent developments in diisocyanate asthma.
Topics: Asthma; Cyanates; Epithelial Cells; Follow-Up Studies; Genetic Predisposition to Disease; Humans; Isocyanates; Lung; Occupational Diseases; Occupational Exposure; Skin; Toluene 2,4-Diisocyanate | 2003 |
Does diisocyanate exposure result in neurotoxicity?
Topics: Animals; Causality; Central Nervous System Agents; Ecotoxicology; Environmental Exposure; Environmental Pollutants; Evidence-Based Practice; Guidelines as Topic; Humans; Isocyanates; Neurotoxicity Syndromes; Occupational Exposure; Peripheral Nervous System Agents; Toluene 2,4-Diisocyanate | 2014 |
A Review of the Surface Modification of Cellulose and Nanocellulose Using Aliphatic and Aromatic Mono- and Di-Isocyanates.
Topics: Cellulose; Environmental Monitoring; Humans; Isocyanates; Nanostructures; Toluene 2,4-Diisocyanate | 2019 |
Absorption, distribution, metabolism, and excretion of methylene diphenyl diisocyanate and toluene diisocyanate: Many similarities and few differences.
Topics: Asthma; Chemical Phenomena; Humans; Isocyanates; Toluene 2,4-Diisocyanate | 2022 |
7 trial(s) available for toluene 2,4-diisocyanate and cyanates
| Article | Year |
|---|---|
Effect of antiasthma drugs on asthmatic reactions induced by toluene diisocyanate in sensitized subjects.
Topics: Adrenergic beta-Agonists; Airway Resistance; Asthma; Bronchial Provocation Tests; Bronchodilator Agents; Cyanates; Humans; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 1990 |
Ketotifen does not inhibit asthmatic reactions induced by toluene di-isocyanate in sensitized subjects.
Topics: Asthma; Cyanates; Double-Blind Method; Forced Expiratory Volume; Humans; Hypersensitivity, Delayed; Immunization; Ketotifen; Methacholine Chloride; Methacholine Compounds; Random Allocation; Toluene 2,4-Diisocyanate | 1989 |
Dexamethasone isonicotinate inhibits dual and late asthmatic reactions but not the increase of airway responsiveness induced by toluene diisocyanate in sensitized subjects.
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Cyanates; Dexamethasone; Dexamethasone Isonicotinate; Female; Humans; Male; Toluene 2,4-Diisocyanate | 1989 |
Protective effect of antiasthma drugs on late asthmatic reactions and increased airway responsiveness induced by toluene diisocyanate in sensitized subjects.
Topics: Asthma; Beclomethasone; Bronchial Provocation Tests; Clinical Trials as Topic; Cromolyn Sodium; Cyanates; Delayed-Action Preparations; Double-Blind Method; Forced Expiratory Volume; Humans; Immunization; Lung; Methacholine Chloride; Methacholine Compounds; Placebos; Random Allocation; Respiratory System; Theophylline; Time Factors; Toluene 2,4-Diisocyanate; Verapamil | 1987 |
Prednisone inhibits late asthmatic reactions and airway inflammation induced by toluene diisocyanate in sensitized subjects.
Topics: Adult; Albumins; Asthma; Bronchi; Bronchial Provocation Tests; Cyanates; Exudates and Transudates; Female; Forced Expiratory Volume; Humans; Inflammation; Leukocytosis; Male; Middle Aged; Prednisone; Respiratory System; Therapeutic Irrigation; Toluene 2,4-Diisocyanate | 1987 |
Protective effect of nifedipine upon specific bronchial responses to isocyanates.
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Clinical Trials as Topic; Constriction, Pathologic; Cyanates; Humans; Male; Nifedipine; Occupational Diseases; Random Allocation; Toluene 2,4-Diisocyanate | 1983 |
Determination of toluenediamines in urine of workers occupationally exposed to isocyanates by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Isocyanates; Isomerism; Occupational Exposure; Toluene 2,4-Diisocyanate | 1996 |
316 other study(ies) available for toluene 2,4-diisocyanate and cyanates
| Article | Year |
|---|---|
Mechanism of respiratory injury by TDI (toluene disocyanate).
Topics: Cyanates; Cyclic AMP; Depression, Chemical; Histamine Release; Humans; In Vitro Techniques; Lung Diseases; Stimulation, Chemical; Toluene 2,4-Diisocyanate | 1975 |
Toluene diisocyanate pulmonary disease: immunopharmacologic and mecholyl challenge studies.
Topics: Administration, Intranasal; Aerosols; Cyanates; Cyclic AMP; Histamine Release; Isoproterenol; Lymphocytes; Methacholine Compounds; Occupational Diseases; Receptors, Adrenergic, beta; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 1977 |
Longitudinal study of workers employed in the manufacture of toluene-diisocyanate.
Topics: Antibodies; Cyanates; Cyclic AMP; Environmental Exposure; Environmental Pollution; Histamine Release; Humans; Immunoglobulins; Longitudinal Studies; Occupational Diseases; Respiratory Function Tests; Respiratory Tract Diseases; Skin Tests; Surveys and Questionnaires; Toluene 2,4-Diisocyanate | 1977 |
Toluene diisocyanate.
Topics: Air Pollutants; Air Pollutants, Occupational; Chemical Industry; Cyanates; Forced Expiratory Volume; Humans; Lung; Male; Toluene 2,4-Diisocyanate | 1978 |
Toluene diisocyanate.
Topics: Air Pollutants; Air Pollutants, Occupational; Asthma; Cyanates; Dose-Response Relationship, Drug; Humans; Maximum Allowable Concentration; Occupational Diseases; Toluene 2,4-Diisocyanate | 1978 |
Toluene diisocyanate.
Topics: Air Pollutants; Air Pollutants, Occupational; Cyanates; Forced Expiratory Volume; Humans; Lung; Toluene 2,4-Diisocyanate | 1978 |
Long-term effects on the health of men engaged in the manufacture of tolylene di-isocyanate.
Topics: Age Factors; Body Height; Chemical Industry; Cyanates; Humans; Male; Occupational Diseases; Prospective Studies; Respiratory Hypersensitivity; Smoking; Spirometry; Toluene; Toluene 2,4-Diisocyanate; Vital Capacity | 1975 |
A retrospective study of clinical, physiologic and immunologic changes in workers exposed to toluene diisocyanate.
Topics: Adult; Agglutination Tests; Air Pollution; Chemical Industry; Cyanates; Environmental Exposure; Humans; Hypersensitivity, Delayed; Immunization, Passive; Middle Aged; Occupational Diseases; Pollen; Respiratory Function Tests; Respiratory Hypersensitivity; Retrospective Studies; Time Factors; Toluene 2,4-Diisocyanate | 1975 |
A technique for dynamic calibration of a continuous toluene diisocyanate monitor.
Topics: Air Pollution; Cyanates; Environmental Exposure; Methods; Occupational Medicine; Toluene 2,4-Diisocyanate | 1975 |
Letter: TDI vapor concentrations.
Topics: Air Pollutants; Air Pollutants, Occupational; Cyanates; Ethylenediamines; Methods; Occupational Medicine; Toluene 2,4-Diisocyanate | 1975 |
Respiratory effects in toluene diisocyanate manufacture: a multidisciplinary approach.
Topics: Air Pollutants, Occupational; Antibodies; Chemical Industry; Cyanates; Dose-Response Relationship, Drug; Environmental Exposure; Eosinophils; Humans; Immunoglobulins; Leukocyte Count; Louisiana; Lymphocyte Activation; Maximum Allowable Concentration; Occupational Diseases; Occupational Medicine; Respiratory Function Tests; Respiratory Tract Diseases; Serum Albumin; Skin Tests; Toluene 2,4-Diisocyanate | 1975 |
Epidemiology of toluene diisocyanate (TDI)-induced respiratory disease.
Topics: Asthma; Bronchitis; Chemical Industry; Cyanates; Environmental Exposure; Eosinophils; Forced Expiratory Volume; Humans; Leukocyte Count; Lung Diseases, Obstructive; Maximum Allowable Concentration; Occupational Diseases; Respiratory Tract Diseases; Toluene 2,4-Diisocyanate | 1975 |
Occupational type test for the etiological diagnosis of asthma due to toluene di-isocyanate.
Topics: Acetylcholine; Adult; Aerosols; Asthma; Bronchi; Cyanates; Evaluation Studies as Topic; Forced Expiratory Volume; Humans; Male; Methods; Occupational Diseases; Toluene 2,4-Diisocyanate | 1976 |
[A supplement to the method of determining 2,4-toluilendiisocyanate in the air].
Topics: Air Pollutants; Air Pollutants, Occupational; Cyanates; Methods; Toluene 2,4-Diisocyanate | 1975 |
[Asthma caused by di-isocyanate].
Topics: Asthma; Cyanates; Environmental Exposure; Humans; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate | 1976 |
[Isocyanate poisoning].
Topics: Air Pollutants; Air Pollutants, Occupational; Animals; Asthma; Bronchitis; Cyanates; Humans; Occupational Medicine; Toluene 2,4-Diisocyanate | 1975 |
Accidental exposure to isocyanate fumes in a group of firemen.
Topics: Adult; Cyanates; Fires; Follow-Up Studies; Forced Expiratory Volume; Gastrointestinal Diseases; Humans; Male; Occupational Diseases; Respiratory Tract Diseases; Smoking; Toluene 2,4-Diisocyanate; Vital Capacity | 1976 |
Neurological complications after a single severe exposure to toluene di-isocyanate.
Topics: Adult; Cyanates; Depression; Fires; Headache; Humans; Male; Memory Disorders; Mental Recall; Middle Aged; Nervous System Diseases; Occupational Diseases; Personality Disorders; Time Factors; Toluene 2,4-Diisocyanate; Wechsler Scales | 1976 |
Asthma due to non-occupational exposure to toluene (tolylene) di-isocyanate.
Topics: Adult; Air Pollutants; Air Pollutants, Occupational; Asthma; Cyanates; Environmental Exposure; Female; Humans; Male; Middle Aged; Time Factors; Toluene 2,4-Diisocyanate; Ventilation | 1976 |
[Asthma and respiratory symptome induced by isocyanates].
Topics: Adult; Asthma; Bronchitis; Cyanates; Environmental Exposure; Female; Humans; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate | 1976 |
Toluene diisocyanate (TDI) pulmonary disease: immunologic and inhalation challenge studies.
Topics: Airway Obstruction; Allergens; Antibodies; Cyanates; Eosinophils; Humans; Immunoglobulin E; Immunoglobulin G; Intradermal Tests; Leukocyte Count; Lymphocyte Activation; Passive Cutaneous Anaphylaxis; Radioimmunoassay; Respiratory Hypersensitivity; Serum Albumin; Skin Tests; Toluene 2,4-Diisocyanate | 1976 |
Hypersensitivity pneumonitis after exposure to isocyanates.
Topics: Animals; Cyanates; Dyspnea; Humans; Lung; Male; Middle Aged; Pneumonia; Prednisone; Rabbits; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 1976 |
Determination of free toluene diisocyanate in polyurethane prepolymers by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Cyanates; Polyurethanes; Toluene 2,4-Diisocyanate | 1976 |
Cholinesterases in human toluendiisocyanate exposure.
Topics: Adult; Cholinesterases; Cyanates; Environmental Exposure; Erythrocytes; Humans; Toluene 2,4-Diisocyanate | 1976 |
[Occupational liver pathology induced by toluylene diisocyanate].
Topics: Adult; Chemical and Drug Induced Liver Injury; Cyanates; Female; Humans; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate | 1976 |
[TDI determination in polyurethane paints and in work environment (author's transl)].
Topics: Air Pollutants; Air Pollutants, Occupational; Cyanates; Paint; Polyurethanes; Toluene 2,4-Diisocyanate | 1976 |
TDI vapor concentrations.
Topics: Air Pollutants; Air Pollutants, Occupational; Catalysis; Chromatography, Gas; Cyanates; Ethylenediamines; Toluene 2,4-Diisocyanate | 1977 |
Toluene di-isocyanate in industry.
Topics: Air Pollutants; Air Pollutants, Occupational; Cyanates; Environmental Exposure; Occupational Medicine; Toluene 2,4-Diisocyanate | 1977 |
The in vitro effect of toluene diisocyanate on lymphocyte cyclic adenosine monophosphate production by isoproterenol, prostaglandin, and histamine: a possible mode of action.
Topics: Asthma; Cyanates; Cyclic AMP; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Interactions; Histamine; Humans; In Vitro Techniques; Isoproterenol; Lung; Lymphocytes; Prostaglandins E; Solvents; Toluene 2,4-Diisocyanate | 1977 |
Chronic pulmonary function loss from exposure to toluene diisocyanate.
Topics: Adult; Cyanates; Environmental Exposure; Female; Forced Expiratory Volume; Humans; Lung; Lung Diseases; Male; Occupational Diseases; Toluene 2,4-Diisocyanate | 1977 |
Analysis of toluene diisocyanate (TDI) and p, p1-diphenylmethane diisocyanate (MDI) in air.
Topics: Air; Benzhydryl Compounds; Colorimetry; Cyanates; Toluene 2,4-Diisocyanate | 1977 |
Toluene di-isocyanate (TDI).
Topics: Asthma; Cyanates; Humans; Nasal Polyps; Occupational Diseases; Respiratory System; Toluene 2,4-Diisocyanate; United Kingdom | 1977 |
A method using toluene-2,4-diisocyanate and glutaraldehyde to stabilize and conjugate antigens to erythrocytes for use in passive hemagglutination tests.
Topics: Aldehydes; Animals; Antigens; Binding Sites; Blood Preservation; Cyanates; Erythrocytes; Glutaral; Hemagglutination Tests; Hemolysis; Humans; Male; Rabbits; Toluene 2,4-Diisocyanate | 1978 |
Recurrent nocturnal asthma due to tolylene di-isocyanate: a case report.
Topics: Adult; Allergens; Asthma; Circadian Rhythm; Cyanates; Humans; Male; Occupational Diseases; Occupations; Recurrence; Toluene 2,4-Diisocyanate | 1978 |
Use of foam for the emergency suppression of vapour emissions from organic isocyanate liquid surfaces.
Topics: Accidents; Cyanates; Fire Extinguishing Systems; Fires; Toluene 2,4-Diisocyanate; Volatilization | 1978 |
Intersociety Committee (ISC) methods of air sampling and analysis.
Topics: Air; Amines; Benzhydryl Compounds; Chlorides; Chlorine; Cyanates; Cyanides; Fluorides; Hydrofluoric Acid; Nitrogen Dioxide; Ozone; Toluene 2,4-Diisocyanate | 1975 |
Serologic test for toluene diisocyanate (TDI) antibodies.
Topics: Antibodies; Cyanates; Dermatitis, Occupational; Humans; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 1978 |
Environmental characterization of toluene diisocyanate (TDI) in a manufacturing plant.
Topics: Air Pollutants; Air Pollutants, Occupational; Chemical Industry; Cyanates; Environmental Exposure; Humans; Maximum Allowable Concentration; Toluene 2,4-Diisocyanate | 1978 |
Tolyl-specific IgE antibodies in workders with hypersensitivity to toluene diisocyanate.
Topics: Antibodies; Antibody Specificity; Cyanates; Environmental Exposure; Haptens; Humans; Hypersensitivity; Immunoglobulin E; Occupational Diseases; Radioimmunoassay; Toluene 2,4-Diisocyanate | 1978 |
[Bronchial asthma presumably caused by isocyanate in "Yamanaka, Japan-Ware" workers (author's transl)].
Topics: Adult; Asthma; Cyanates; Female; Humans; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate | 1978 |
A calibrated delivery system for inhalation challenge of toluene di-isocyanate vapor.
Topics: Cyanates; Humans; Lung; Methods; Respiration; Toluene 2,4-Diisocyanate | 1978 |
Toluene di-isocyanate-induced asthma. I. Reactions to TDI, MDI, HDI and histamine.
Topics: Asthma; Benzhydryl Compounds; Cyanates; Hexamethonium Compounds; Histamine; Humans; Male; Toluene 2,4-Diisocyanate | 1979 |
Toluene di-isocyanate-induced asthma. II. Inhalation challenge tests and bronchial reactivity studies.
Topics: Adult; Asthma; Cyanates; Exercise Test; Histamine; Humans; Middle Aged; Respiratory Function Tests; Rhinitis, Allergic, Seasonal; Smoking; Toluene 2,4-Diisocyanate | 1979 |
Patterns of airway reactivity to asthma produced by exposure to toluene di-isocyanate.
Topics: Air Pollutants; Air Pollutants, Occupational; Airway Resistance; Asthma; Bronchi; Cyanates; Dose-Response Relationship, Drug; Dose-Response Relationship, Immunologic; Drug Hypersensitivity; Humans; Maximal Expiratory Flow-Volume Curves; Methacholine Compounds; Occupational Diseases; Ohio; Toluene 2,4-Diisocyanate | 1979 |
Evidence of a safe level of TDI.
Topics: Cyanates; Forced Expiratory Volume; Humans; Lung Diseases; Occupational Diseases; Respiratory Hypersensitivity; Time Factors; Toluene 2,4-Diisocyanate | 1979 |
Inhalation challenge and pharmacologic studies of toluene diisocyanate (TDI)-sensitive workers.
Topics: Aerosols; Complement System Proteins; Cromolyn Sodium; Cyanates; Cyclic AMP; Environmental Exposure; Histamine; Humans; Hypersensitivity; Lymphocytes; Methacholine Compounds; Occupational Diseases; Toluene 2,4-Diisocyanate | 1979 |
Longitudinal study of tolyl-reactive IgE antibodies in workers hypersensitive to TDI.
Topics: Adult; Bronchi; Cyanates; Female; Humans; Hypersensitivity; Hypersensitivity, Immediate; Immunoglobulin E; Male; Middle Aged; Radioallergosorbent Test; Skin Tests; Toluene 2,4-Diisocyanate | 1979 |
Peak flow rate records in the diagnosis of occupational asthma due to isocyanates.
Topics: Asthma; Cyanates; England; Humans; Occupational Diseases; Peak Expiratory Flow Rate; Printing; Time Factors; Toluene 2,4-Diisocyanate | 1979 |
[Diseases caused by diisocyanates. 1. Irritation of the respiratory system and skin].
Topics: Cyanates; Dermatitis, Contact; Dermatitis, Occupational; Environmental Exposure; Fever; Humans; Lung Diseases; Maximum Allowable Concentration; Occupational Diseases; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 1978 |
[Diseases caused by diisocyanates. 2. Diisocyanate asthma].
Topics: Asthma; Cyanates; Humans; Immune Complex Diseases; Immunity, Cellular; Immunoglobulin E; Occupational Diseases; Toluene 2,4-Diisocyanate | 1979 |
[Determination of toluidine diisocyanate and 4,4'-diphenylmethane diisocyanate in air].
Topics: Aerosols; Air Pollutants; Air Pollutants, Occupational; Benzhydryl Compounds; Cyanates; Methods; Toluene 2,4-Diisocyanate; Volatilization | 1979 |
Induction of murine reaginic antibodies by toluene diisocyanate. An animal model of immediate hypersensitivity reactions to isocyanates.
Topics: Animals; Antibody Formation; Carrier Proteins; Cyanates; Drug Hypersensitivity; Female; Hypersensitivity, Immediate; Immunization; Injections, Intraperitoneal; Injections, Intravenous; Male; Mice; Mice, Inbred Strains; Models, Biological; Ovalbumin; Passive Cutaneous Anaphylaxis; Reagins; Serum Albumin; Toluene 2,4-Diisocyanate | 1979 |
Inhalation challenge testing with toluene diisocyanate.
Topics: Air Pollutants; Air Pollutants, Occupational; Asthma; Bronchial Provocation Tests; Cyanates; Humans; Occupational Diseases; Toluene 2,4-Diisocyanate | 1979 |
A proposed standardized method for bronchoprovocation tests in toluene diisocyanate--induced asthma.
Topics: Air Pollutants; Air Pollutants, Occupational; Asthma; Bronchial Provocation Tests; Cyanates; Humans; Occupational Diseases; Toluene 2,4-Diisocyanate | 1979 |
Sensory irritation by toluene diisocyanate in single and repeated exposures.
Topics: Animals; Cyanates; Irritants; Male; Mice; Sensory Thresholds; Time Factors; Toluene 2,4-Diisocyanate | 1979 |
[On the induction of contact sensitivity by tolylene diisocyanate (TDI) in mice (author's transl)].
Topics: Animals; Cyanates; Dermatitis, Contact; Female; Mice; Toluene 2,4-Diisocyanate | 1979 |
Chemical characterization of isocyanate-protein conjugates.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Cyanates; Humans; Hydrolysis; Protein Binding; Proteins; Serum Albumin; Succinates; Toluene 2,4-Diisocyanate | 1979 |
A new method for the generation of standard atmospheres of organo isocyanates.
Topics: Cyanates; Membranes, Artificial; Permeability; Polytetrafluoroethylene; Silicones; Toluene 2,4-Diisocyanate | 1979 |
[On the pathogenesis of isocyanate-induced asthma].
Topics: Adult; Asthma; Cyanates; Humans; Middle Aged; Occupational Diseases; Radioallergosorbent Test; Respiratory Function Tests; Toluene 2,4-Diisocyanate | 1979 |
Presence of tolyl-specific IgE and absence of IgG antibodies in workers exposed to toluene diisocyanate.
Topics: Cyanates; Drug Hypersensitivity; Humans; Immunoenzyme Techniques; Immunoglobulin E; Immunoglobulin G; Occupational Diseases; Radioimmunoassay; Toluene 2,4-Diisocyanate | 1979 |
Bathtub refinisher's lung: an unusual response to toluene diisocyanate.
Topics: Alveolitis, Extrinsic Allergic; Cyanates; Humans; Intradermal Tests; Lymphocyte Activation; Male; Middle Aged; Occupational Diseases; Respiratory Function Tests; Toluene 2,4-Diisocyanate | 1978 |
[A case of hypersensitivity pneumonitis due to isocyanate exposure showing progression even two months after removal of the antigen].
Topics: Aged; Alveolitis, Extrinsic Allergic; Cyanates; Humans; Isocyanates; Male; Occupational Exposure; Paint; Toluene 2,4-Diisocyanate | 1992 |
[A case of hypersensitivity pneumonitis in which serum specific antibodies for three species of isocyanate molecules were demonstrated].
Topics: Alveolitis, Extrinsic Allergic; Antibodies; Cyanates; Humans; Isocyanates; Male; Middle Aged; Paint; Toluene 2,4-Diisocyanate | 1992 |
Comparison of clinical and experimental data from an animal model of pulmonary immunologic sensitivity.
Topics: Allergens; Animals; Antigen-Antibody Reactions; Atmosphere Exposure Chambers; Cyanates; Disease Models, Animal; Equipment Design; Guinea Pigs; Lung Diseases; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 1991 |
Isocyanate-induced asthma: results of inhalation tests with TDI, MDI and methacholine.
Topics: Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Isocyanates; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Respiratory Function Tests; Skin Tests; Toluene 2,4-Diisocyanate | 1991 |
A new tool for sampling airborne isocyanates.
Topics: Air Pollutants; Aniline Compounds; Chemistry Techniques, Analytical; Cyanates; Isocyanates; Toluene 2,4-Diisocyanate | 1991 |
Persistence of toluene diisocyanate-induced asthma despite negligible workplace exposures.
Topics: Asthma; Cyanates; Forced Expiratory Volume; Humans; Longitudinal Studies; Occupational Diseases; Spirometry; Toluene 2,4-Diisocyanate; Vital Capacity | 1990 |
Immunologic hemorrhagic pneumonia caused by isocyanates.
Topics: Acute Disease; Adult; Cyanates; Enzyme-Linked Immunosorbent Assay; Hemorrhage; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Lung; Male; Occupational Diseases; Pneumonia; Radiography; Serum Albumin; Toluene 2,4-Diisocyanate | 1990 |
Eicosanoid release from human bronchial epithelial cells upon exposure to toluene diisocyanate in vitro.
Topics: Arachidonic Acid; Arachidonic Acids; Bronchi; Cell Survival; Cells, Cultured; Cyanates; Dinoprost; Dinoprostone; Eicosanoids; Epithelium; Humans; Hydroxyeicosatetraenoic Acids; L-Lactate Dehydrogenase; Leukotriene B4; Toluene 2,4-Diisocyanate | 1990 |
Toluene diisocyanate-induced conformational changes of serum albumin: a study on repeated inhalations in guinea-pigs.
Topics: Administration, Inhalation; Animals; Antibody Formation; Cyanates; Dermatitis, Contact; Dose-Response Relationship, Drug; Guinea Pigs; Male; Protein Conformation; Serum Albumin; Spectrophotometry, Infrared; Toluene 2,4-Diisocyanate | 1990 |
Neutrophil chemotactic activity in toluene diisocyanate (TDI)-induced asthma.
Topics: Animals; Asthma; Basophils; Bronchial Provocation Tests; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Chromatography, Gel; Cyanates; Forced Expiratory Volume; Humans; Mast Cells; Methacholine Chloride; Methacholine Compounds; Mites; Molecular Weight; Neutrophils; Time Factors; Toluene 2,4-Diisocyanate | 1990 |
Persistent reactive airway dysfunction syndrome after exposure to toluene diisocyanate.
Topics: Accidents, Traffic; Adult; Asthma; Cyanates; Follow-Up Studies; Humans; Lung; Male; Middle Aged; Occupational Diseases; Prednisolone; Social Control, Formal; Time Factors; Toluene 2,4-Diisocyanate | 1990 |
Airway inflammation and late asthmatic reactions.
Topics: Asthma; Bronchi; Cyanates; Humans; Pulmonary Ventilation; Time Factors; Toluene 2,4-Diisocyanate | 1990 |
Leukotriene B4 and late asthmatic reactions induced by toluene diisocyanate.
Topics: Adult; Asthma; Bronchoalveolar Lavage Fluid; Chromatography, High Pressure Liquid; Cyanates; Female; Humans; Leukocyte Count; Leukotriene B4; Male; Neutrophils; Toluene 2,4-Diisocyanate | 1990 |
Evidence that toluene diisocyanate activates the efferent function of capsaicin-sensitive primary afferents.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cyanates; Electric Stimulation; Ganglia, Autonomic; In Vitro Techniques; Male; Muscle Denervation; Neurons, Efferent; Rats; Rats, Inbred Strains; Toluene 2,4-Diisocyanate; Urinary Bladder | 1990 |
The use of an immunoassay index for antibodies against isocyanate human protein conjugates and application to human isocyanate disease.
Topics: Antibodies; Antibody Specificity; Blood Proteins; Cyanates; Enzyme-Linked Immunosorbent Assay; Haptens; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Occupational Diseases; Toluene 2,4-Diisocyanate | 1990 |
Respiratory symptoms and pulmonary function of workers exposed to cork dust, toluene diisocyanate and conidia.
Topics: Adult; Alveolitis, Extrinsic Allergic; Chronic Disease; Confounding Factors, Epidemiologic; Cross-Sectional Studies; Cyanates; Environmental Exposure; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Respiratory Function Tests; Respiratory Hypersensitivity; Risk Factors; Spain; Spores, Fungal; Toluene 2,4-Diisocyanate; Trees | 1990 |
Bronchoalveolar lavage and morphology of the airways after cessation of exposure in asthmatic subjects sensitized to toluene diisocyanate.
Topics: Adult; Asthma; Biopsy; Bronchi; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cell Count; Cyanates; Female; Humans; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate | 1990 |
Occupational asthma due to isocyanates in Singapore.
Topics: Adolescent; Adult; Aged; Asthma; Cyanates; Female; Humans; Infant; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate | 1990 |
Simple management of cerebrospinal fluid rhinorrhea after pituitary surgery.
Topics: Aprotinin; Cerebrospinal Fluid Rhinorrhea; Cyanates; Cyanoacrylates; Drug Combinations; Factor XIII; Fibrin Tissue Adhesive; Fibrinogen; Humans; Needles; Pituitary Gland; Postoperative Complications; Punctures; Sella Turcica; Sphenoid Sinus; Thrombin; Tissue Adhesives; Toluene 2,4-Diisocyanate | 1986 |
Tachykinins mediate the acute increase in airway responsiveness caused by toluene diisocyanate in guinea pigs.
Topics: Acetylcholine; Airway Resistance; Animals; Capsaicin; Cyanates; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Guinea Pigs; Male; Neuropeptides; Pulmonary Edema; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Tachykinins; Toluene 2,4-Diisocyanate; Trachea | 1987 |
Toluene diisocyanate increases airway responsiveness to substance P and decreases airway neutral endopeptidase.
Topics: Airway Resistance; Animals; Cyanates; Endopeptidases; Esophagus; Glycopeptides; Guinea Pigs; In Vitro Techniques; Lung; Neprilysin; Protease Inhibitors; Substance P; Toluene 2,4-Diisocyanate; Trachea | 1988 |
A tachykinin receptor antagonist inhibits and an inhibitor of tachykinin metabolism potentiates toluene diisocyanate-induced airway hyperresponsiveness in guinea pigs.
Topics: Acetylcholine; Animals; Cyanates; Depression, Chemical; Drug Synergism; Glycopeptides; Guinea Pigs; Male; Receptors, Neurotransmitter; Receptors, Tachykinin; Respiratory Hypersensitivity; Substance P; Tachykinins; Toluene 2,4-Diisocyanate | 1988 |
Hypersensitivity pneumonitis induced by toluene diisocyanate: sequelae of continuous exposure.
Topics: Adult; Alveolitis, Extrinsic Allergic; Bronchoalveolar Lavage Fluid; Cyanates; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin A; Immunoglobulin G; Leukocyte Count; Lymphocyte Activation; Lymphocytes; Male; Occupational Diseases; Serum Albumin; Toluene 2,4-Diisocyanate | 1989 |
Immunologic specificity of isocyanate-induced IgE antibodies in serum from 10 sensitized workers.
Topics: Antibody Specificity; Asthma; Carrier Proteins; Cyanates; Haptens; Humans; Immunoglobulin E; Isocyanates; Male; Occupational Diseases; Radioallergosorbent Test; Serum Albumin; Toluene 2,4-Diisocyanate | 1989 |
In vitro effect of toluene diisocyanate on beta adrenergic and muscarinic receptor function in lung tissue of the rat.
Topics: Animals; Cyanates; In Vitro Techniques; Lung; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Muscarinic; Toluene 2,4-Diisocyanate; Trachea | 1989 |
A diffusive sampler for personal monitoring of toluene diisocyanate (TDI) exposure; Part I: Design of the dosimeter.
Topics: Air Pollutants, Occupational; Cyanates; Environmental Monitoring; Equipment Design; Spectrometry, Fluorescence; Spectrophotometry; Toluene 2,4-Diisocyanate; Wind | 1989 |
A diffusive sampler for personal monitoring of toluene diisocyanate (TDI) exposure; Part II: Laboratory and field evaluation of the dosimeter.
Topics: Air Pollutants, Occupational; Atmospheric Pressure; Calibration; Cyanates; Environmental Monitoring; Equipment Design; Evaluation Studies as Topic; Humidity; Hydrolysis; Morpholines; Nitrogen Dioxide; Temperature; Toluene 2,4-Diisocyanate | 1989 |
Effect of substrate condition and substituted phenols and methacrylates on toluene diisocyanate/dentin bond strengths.
Topics: Acrylates; Cyanates; Dental Cements; Dentin; Humans; Ligands; Methacrylates; Molar; Phenols; Structure-Activity Relationship; Toluene 2,4-Diisocyanate | 1989 |
[A comparative evaluation of photometric methods for determining 2,4-toluene diisocyanate in the air].
Topics: Air Pollutants, Occupational; Cyanates; Evaluation Studies as Topic; Photometry; Toluene 2,4-Diisocyanate | 1989 |
[Bronchial asthma caused by isocyanate in the internal/external environment].
Topics: Asthma; Cyanates; Humans; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate | 1989 |
An epidemiologic investigation of forced expiratory volume at 1 second and respiratory symptoms among employees of a toluene diisocyanate production plant.
Topics: Adult; Age Factors; Cross-Sectional Studies; Cyanates; Environmental Exposure; Female; Forced Expiratory Volume; Humans; Male; Occupational Diseases; Respiratory Tract Diseases; Sex Factors; Texas; Toluene 2,4-Diisocyanate | 1989 |
Uptake and distribution of 14C during and following inhalation exposure to radioactive toluene diisocyanate.
Topics: Administration, Inhalation; Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Cyanates; Guinea Pigs; Isocyanates; Male; Metabolic Clearance Rate; Radiochemistry; Regression Analysis; Structure-Activity Relationship; Tissue Distribution; Toluene 2,4-Diisocyanate | 1989 |
Hypersensitivity pneumonitis and toluene diisocyanate.
Topics: Alveolitis, Extrinsic Allergic; Cyanates; Humans; Male; Occupational Diseases; Toluene 2,4-Diisocyanate | 1989 |
[Occupational toluene diisocyanate (TDI) asthma--inhalation challenge test and TDI-HSA (human serum albumin) skin test and detection of specific IgE].
Topics: Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Immunoglobulin E; Male; Occupational Diseases; Serum Albumin; Skin Tests; Toluene 2,4-Diisocyanate | 1989 |
Test atmospheres of diisocyanates with special reference to controlled exposure of humans.
Topics: Air Pollutants; Atmosphere Exposure Chambers; Cyanates; Environmental Monitoring; Equipment Design; Humans; Isocyanates; Male; Toluene 2,4-Diisocyanate | 1989 |
[Determination of toluene diisocyanates in aqueous solutions].
Topics: Chromatography, Thin Layer; Cyanates; Gas Chromatography-Mass Spectrometry; Solutions; Toluene 2,4-Diisocyanate | 1987 |
Importance of airway inflammation for late asthmatic reactions induced by toluene diisocyanate in sensitized subjects.
Topics: Adult; Asthma; Cyanates; Humans; Inflammation; Male; Methacholine Chloride; Methacholine Compounds; Respiratory System; Time Factors; Toluene 2,4-Diisocyanate | 1987 |
Atropine does not inhibit late asthmatic responses induced by toluene-diisocyanate in sensitized subjects.
Topics: Administration, Inhalation; Adult; Airway Resistance; Asthma; Atropine; Carbachol; Cyanates; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate | 1987 |
Contact sensitivity induced in mice by methylene bisphenyl diisocyanate.
Topics: Administration, Cutaneous; Animals; Cross Reactions; Cyanates; Dermatitis, Contact; Disease Models, Animal; Hypersensitivity, Delayed; Immunization, Passive; Isocyanates; Male; Mice; Mice, Inbred C57BL; T-Lymphocytes; Toluene 2,4-Diisocyanate | 1987 |
[Technology of producing p-toluene isocyanate (C6H4CH3NCO) and a human albumin complex for clinical purposes].
Topics: Antibodies; Cyanates; Drug Hypersensitivity; Humans; Isocyanates; Serum Albumin; Toluene 2,4-Diisocyanate | 1987 |
A nasal allergy model developed in the guinea pig by intranasal application of 2,4-toluene diisocyanate.
Topics: Administration, Intranasal; Animals; Cyanates; Disease Models, Animal; Guinea Pigs; Histamine; Male; Mucus; Nasal Mucosa; Passive Cutaneous Anaphylaxis; Rhinitis, Allergic, Perennial; Toluene 2,4-Diisocyanate | 1988 |
Trace analysis of airborne aromatic isocyanates and related aminoisocyanates and diamines using high-performance liquid chromatography with ultraviolet and electrochemical detection.
Topics: Air Pollutants; Air Pollutants, Occupational; Chromatography, High Pressure Liquid; Cyanates; Diamines; Electrochemistry; Microchemistry; Specimen Handling; Spectrophotometry, Ultraviolet; Toluene 2,4-Diisocyanate; Urethane | 1988 |
Sensitisation of guinea pigs by inhalation exposure to low molecular weight chemicals.
Topics: Allergens; Animals; Cyanates; Enzyme-Linked Immunosorbent Assay; Female; Guinea Pigs; Immunoglobulin E; Immunoglobulin G; Lung; Passive Cutaneous Anaphylaxis; Phthalic Acids; Phthalic Anhydrides; Respiration; Toluene 2,4-Diisocyanate; Triazines | 1988 |
[Experimental studies on toluene-diisocyanate (TDI) specific IgG antibodies (II). TDI-specific IgG antibody and TDI conjugated proteins of the mouse skin].
Topics: Albumins; Animals; Antibody Specificity; Cyanates; Dermatitis, Contact; Immunoglobulin G; Male; Mice; Mice, Inbred BALB C; Skin; Toluene 2,4-Diisocyanate | 1988 |
Toluene diisocyanate-induced airway hyperreactivity in guinea pigs depleted of granulocytes.
Topics: Acetylcholine; Agranulocytosis; Animals; Bronchi; Cyanates; Cyclophosphamide; Granulocytes; Guinea Pigs; Leukocyte Count; Toluene 2,4-Diisocyanate | 1988 |
[Reaction-chromatographic method of determining toluylene diisocyanates in the air].
Topics: Air Pollutants; Chromatography; Cyanates; Toluene 2,4-Diisocyanate | 1988 |
Occupational asthma due to toluene diisocyanate among velcro-like tape manufacturers.
Topics: Adhesives; Air Pollutants, Occupational; Asthma; Cyanates; Female; Humans; Male; Occupational Diseases; Respiratory Function Tests; Toluene 2,4-Diisocyanate; Ventilation | 1988 |
Cross-reaction between aromatic isocyanates (TDI and MDI): a specific bronchial provocation test study.
Topics: Adult; Asthma; Bronchial Provocation Tests; Cross Reactions; Cyanates; Female; Humans; Isocyanates; Male; Middle Aged; Occupational Diseases; Polyurethanes; Toluene 2,4-Diisocyanate | 1988 |
TDI--not so toxic?
Topics: Animals; Cyanates; Environmental Exposure; Humans; Lung Diseases; Toluene 2,4-Diisocyanate | 1988 |
Recurrent asthma induced by toluene diisocyanate.
Topics: Adult; Asthma; Chemical Industry; Cyanates; Humans; Male; Methacholine Chloride; Methacholine Compounds; Occupational Diseases; Recurrence; Toluene 2,4-Diisocyanate | 1988 |
Persistent asthma due to isocyanates. A follow-up study of subjects with occupational asthma due to toluene diisocyanate (TDI).
Topics: Asthma; Bronchial Provocation Tests; Chronic Disease; Cyanates; Environmental Exposure; Female; Follow-Up Studies; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Methacholine Compounds; Toluene 2,4-Diisocyanate | 1988 |
Fatal asthma in a subject sensitized to toluene diisocyanate.
Topics: Adult; Asthma; Bronchial Spasm; Cyanates; Environmental Exposure; Humans; Lung; Male; Paint; Polyurethanes; Toluene 2,4-Diisocyanate | 1988 |
[Toxic interstitial pneumonia caused by diisocyanate].
Topics: Adult; Cyanates; Female; Humans; Pulmonary Fibrosis; Toluene 2,4-Diisocyanate | 1988 |
Toluene diisocyanate-induced airway hyperresponsiveness to intravenous acetylcholine: a study on single and repeated exposure in guinea-pigs.
Topics: Acetylcholine; Administration, Inhalation; Airway Resistance; Animals; Cyanates; Dose-Response Relationship, Drug; Drug Synergism; Female; Guinea Pigs; Plethysmography; Toluene 2,4-Diisocyanate | 1988 |
Increased neutrophil leukocyte chemotaxis induced by release of a serum factor in toluene-diisocyanate (TDI) asthma.
Topics: Adult; Asthma; Bronchial Provocation Tests; Chemotactic Factors; Chemotaxis, Leukocyte; Cyanates; Female; Humans; Interleukin-8; Male; Neutrophils; Occupational Diseases; Toluene 2,4-Diisocyanate | 1988 |
Experiences of specific IgE in asthma due to diisocyanates.
Topics: Antibody Formation; Antibody Specificity; Antigen-Antibody Complex; Asthma; Bronchial Provocation Tests; Cyanates; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Isocyanates; Radioallergosorbent Test; Skin Tests; Toluene 2,4-Diisocyanate | 1988 |
[Neurohumoral regulation of the adaptive processes in workers subjected to toluene diisocyanate exposure].
Topics: Adaptation, Physiological; Adult; Cyanates; Environmental Exposure; Humans; Male; Neurotransmitter Agents; Skin Tests; Time Factors; Toluene 2,4-Diisocyanate | 1988 |
A 10-year follow-up study of a group of workers exposed to isocyanates.
Topics: Adult; Cyanates; Female; Follow-Up Studies; Forced Expiratory Volume; Humans; Isocyanates; Lung Diseases, Obstructive; Male; Middle Aged; Occupational Diseases; Smoking; Time Factors; Toluene 2,4-Diisocyanate; Vital Capacity | 1985 |
TDI-induced oculorhinitis and bronchial asthma.
Topics: Asthma; Bronchial Provocation Tests; Cyanates; Endophthalmitis; Humans; Immunoglobulin E; Male; Middle Aged; Occupational Diseases; Paint; Rhinitis; Toluene 2,4-Diisocyanate | 1985 |
Use of repeated CO2 challenges to evaluate the pulmonary performance of guinea pigs exposed to toluene diisocyanate.
Topics: Animals; Atmosphere Exposure Chambers; Body Weight; Bronchial Provocation Tests; Bronchitis; Carbon Dioxide; Cyanates; Female; Guinea Pigs; Plethysmography, Whole Body; Tidal Volume; Toluene 2,4-Diisocyanate | 1985 |
Symptoms and lung function in low-exposure to TDI by polyurethane foam manufacturing.
Topics: Adult; Air Pollutants, Occupational; Cyanates; Environmental Exposure; Female; Humans; Lung; Male; Polyurethanes; Smoking; Toluene 2,4-Diisocyanate | 1985 |
Time course of the increase in airway responsiveness associated with late asthmatic reactions to toluene diisocyanate in sensitized subjects.
Topics: Adolescent; Adult; Airway Resistance; Asthma; Cyanates; Female; Humans; Hypersensitivity, Delayed; Male; Toluene 2,4-Diisocyanate | 1985 |
Combined asthma and alveolitis due to diphenylmethane diisocyanate (MDI) with demonstration of no crossed respiratory reactivity to toluene diisocyanate (TDI).
Topics: Adult; Alveolitis, Extrinsic Allergic; Asthma; Bronchi; Bronchial Provocation Tests; Cyanates; Female; Forced Expiratory Volume; Humans; Isocyanates; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Neutrophils; Therapeutic Irrigation; Toluene 2,4-Diisocyanate | 1985 |
Detection of urinary amine metabolites in toluene diisocyanate exposed rats.
Topics: Amines; Animals; Chemical Phenomena; Chemistry; Chromatography, Gas; Cyanates; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Half-Life; Rats; Toluene 2,4-Diisocyanate | 1985 |
Modified Marcali method for the determination of total toluenediisocyanate in air.
Topics: Air Pollutants, Occupational; Chemical Phenomena; Chemistry; Cyanates; Isomerism; Spectrophotometry; Toluene 2,4-Diisocyanate | 1985 |
Toluene diisocyanate and lung function.
Topics: Chemical Industry; Cyanates; Humans; Lung Diseases; Occupational Diseases; Respiratory Function Tests; Smoking; Toluene 2,4-Diisocyanate | 1985 |
Occupational asthma in a steel coating plant.
Topics: Adult; Asthma; Cross-Sectional Studies; Cyanates; Disease Outbreaks; England; Female; Follow-Up Studies; Humans; Male; Metallurgy; Middle Aged; Occupational Diseases; Peak Expiratory Flow Rate; Respiratory Function Tests; Skin Tests; Toluene 2,4-Diisocyanate | 1985 |
[Additional findings on contact sensitivity of mice induced by toluene diisocyanate (TDI)].
Topics: Animals; Cyanates; Dermatitis, Contact; Disease Models, Animal; Female; Fluocinolone Acetonide; Mice; Toluene 2,4-Diisocyanate | 1985 |
[Comparison of stationary and person-bound measurements of toluene diisocyanate in workrooms of a polyurethane foam-producing plant].
Topics: Air Pollutants, Occupational; Air Pollution; Amines; Chemical Industry; Cyanates; Environmental Exposure; Methods; Polyurethanes; Temperature; Toluene 2,4-Diisocyanate | 1985 |
[Toluene diisocyanate induced asthma].
Topics: Adult; Asthma; Cyanates; Female; Humans; Immunoglobulin E; Male; Middle Aged; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 1985 |
Prednisone inhibits late asthmatic reactions and the associated increase in airway responsiveness induced by toluene-diisocyanate in sensitized subjects.
Topics: Adult; Asthma; Cyanates; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Prednisone; Respiratory System; Toluene 2,4-Diisocyanate | 1985 |
Airway hyperresponsiveness and inflammation induced by toluene diisocyanate in guinea pigs.
Topics: Acetylcholine; Animals; Cyanates; Eosinophils; Guinea Pigs; Inflammation; Male; Neutrophils; Ozone; Respiratory System; Smoking; Toluene 2,4-Diisocyanate; Trachea; Tracheitis | 1985 |
[Experimental studies on toluene-diisocyanate (TDI) specific IgG antibodies. (I). Detection in the serum from toluene-diisocyanate skin-sensitized mice].
Topics: Animals; Antibodies; Blood Proteins; Cyanates; Dermatitis, Contact; Immunoglobulin G; Male; Mice; Mice, Inbred BALB C; Toluene 2,4-Diisocyanate | 1985 |
Absence of respiratory effects in subjects exposed to low concentrations of TDI and MDI: a reevaluation.
Topics: Cyanates; Environmental Exposure; Female; Forced Expiratory Volume; Humans; Isocyanates; Male; Respiration; Toluene 2,4-Diisocyanate; Vital Capacity | 1985 |
Studies on toluene diisocyanate (TDI)-induced delayed type hypersensitivity.
Topics: Animals; Capillary Permeability; Cyanates; Dexamethasone; Drug Hypersensitivity; Hypersensitivity, Delayed; Indomethacin; Male; Mice; Mice, Inbred ICR; Picryl Chloride; Species Specificity; Toluene 2,4-Diisocyanate | 1985 |
[Functional diagnosis of myocardial diseases in patients exposed to various chemical substances].
Topics: Adolescent; Adult; Cyanates; Female; Heart Function Tests; Humans; Insecticides; Male; Middle Aged; Myocarditis; Occupational Diseases; Toluene 2,4-Diisocyanate | 1985 |
Contact sensitivity in rats induced by tolylene diisocyanate (TDI).
Topics: Animals; Cyanates; Dermatitis, Contact; Hypersensitivity, Delayed; Male; Picryl Chloride; Rats; Rats, Inbred F344; Toluene 2,4-Diisocyanate | 1985 |
Toluene diisocyanate-induced asthma without airway hyperresponsiveness.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Cyanates; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate | 1986 |
Toluene diisocyanate-induced airway hyperreactivity and pathology in the guinea pig.
Topics: Airway Resistance; Animals; Bronchial Provocation Tests; Cyanates; Guinea Pigs; Histamine; Immunoglobulin E; Male; Skin Tests; Time Factors; Toluene 2,4-Diisocyanate | 1986 |
Persistent airways disease caused by toluene diisocyanate.
Topics: Asthma; Bronchial Provocation Tests; Cyanates; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Occupational Diseases; Time Factors; Toluene 2,4-Diisocyanate | 1986 |
Specific bronchial reactivity to toluene diisocyanate: relationship with baseline clinical findings.
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Cyanates; Female; Forced Expiratory Volume; Humans; Lung; Male; Middle Aged; Toluene 2,4-Diisocyanate | 1986 |
Evaluation of air-purifying respirators for protection against toluene diisocyanate vapors.
Topics: Air Pollutants, Occupational; Atmospheric Pressure; Cyanates; Humans; Toluene 2,4-Diisocyanate; Ventilators, Mechanical | 1986 |
Chronic asthma due to toluene diisocyanate.
Topics: Adult; Asthma; Chronic Disease; Cyanates; Forced Expiratory Volume; Humans; Middle Aged; Occupational Diseases; Prognosis; Retrospective Studies; Time Factors; Toluene 2,4-Diisocyanate; Vital Capacity | 1986 |
Morphology of tracheal and bronchial epithelium and type II cells of the peripheral lung of the guinea pig after inhalation of toluene diisocyanate vapors.
Topics: Animals; Bronchi; Cyanates; Cytoplasm; Guinea Pigs; Male; Microscopy, Electron; Pulmonary Alveoli; Respiratory System; Time Factors; Toluene 2,4-Diisocyanate; Trachea | 1986 |
[Health hazards in workers of small scale polyurethane production factory].
Topics: Adolescent; Adult; Aged; Asthma; Chemical Industry; Cyanates; Female; Humans; Isocyanates; Male; Middle Aged; Morbidity; Occupational Diseases; Polyurethanes; Toluene 2,4-Diisocyanate | 1986 |
Determination in urine of diisocyanate-derived amines from occupational exposure by gas chromatography-mass fragmentography.
Topics: Amines; Cyanates; Gas Chromatography-Mass Spectrometry; Humans; Occupational Diseases; Toluene 2,4-Diisocyanate | 1986 |
Toluene diisocyanate.
Topics: Air Pollution; Animals; Chemical Phenomena; Chemistry; Cyanates; Environmental Exposure; Humans; Lethal Dose 50; Mice; Mutagenicity Tests; Phenylenediamines; Polyurethanes; Rats; Rats, Inbred F344; Rubber; Toluene 2,4-Diisocyanate | 1986 |
Determination of toluene diisocyanate in air by HPLC and band-tape monitors.
Topics: Air; Chromatography, High Pressure Liquid; Cyanates; Environmental Monitoring; Humidity; Toluene 2,4-Diisocyanate | 1986 |
Determination of occupational exposure to toluene diisocyanate by biological monitoring.
Topics: Amines; Cyanates; Gas Chromatography-Mass Spectrometry; Indicators and Reagents; Monitoring, Physiologic; Occupational Diseases; Phenylenediamines; Toluene 2,4-Diisocyanate | 1986 |
Specific bronchial reactivity to toluene diisocyanate: dose-response relationship.
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Cyanates; Differential Threshold; Dose-Response Relationship, Drug; Forced Expiratory Volume; Humans; Methacholine Chloride; Methacholine Compounds; Toluene 2,4-Diisocyanate | 1986 |
Evaluation of air-purifying respirators for protection against toluene diisocyanate vapors.
Topics: Air Pollutants, Occupational; Cyanates; Humans; Protective Devices; Respiratory Protective Devices; Toluene 2,4-Diisocyanate | 1986 |
Late, but not early, asthmatic reactions induced by toluene-diisocyanate are associated with increased airway responsiveness to methacholine.
Topics: Adult; Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds; Occupational Diseases; Time Factors; Toluene 2,4-Diisocyanate | 1986 |
[Chemotaxic activity of granulocytes in toluene diisocyanate-induced asthma].
Topics: Adult; Asthma; Chemotaxis, Leukocyte; Cyanates; Female; Humans; Male; Neutrophils; Toluene 2,4-Diisocyanate | 1986 |
Chromosome aberrations and sister-chromatid exchanges induced by technical grade toluene diisocyanate and methylenediphenyl diisocyanate in cultured human lymphocytes.
Topics: Animals; Cells, Cultured; Chromosome Aberrations; Cyanates; Humans; Isocyanates; Lymphocytes; Rats; Sister Chromatid Exchange; Toluene 2,4-Diisocyanate | 1987 |
[A case report on death due to an asthmatic attack observed in a guinea pig with TDI-induced asthma].
Topics: Animals; Asthma; Cyanates; Disease Models, Animal; Guinea Pigs; Lung; Male; Nasal Mucosa; Toluene 2,4-Diisocyanate | 1986 |
Bathtub refinishers' lung.
Topics: Cyanates; Humans; Occupational Diseases; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 1987 |
Bronchoalveolar neutrophilia during late asthmatic reactions induced by toluene diisocyanate.
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Cyanates; Dose-Response Relationship, Drug; Eosinophils; Forced Expiratory Volume; Humans; Leukocyte Count; Methacholine Chloride; Methacholine Compounds; Neutrophils; Pulmonary Alveoli; Therapeutic Irrigation; Time Factors; Toluene 2,4-Diisocyanate | 1987 |
[Body reactivity of workers in contact with the chemical allergen toluene diisocyanate].
Topics: Adult; Allergens; Cyanates; Female; Humans; Immunization; Male; Occupational Diseases; Skin Tests; Toluene 2,4-Diisocyanate | 1987 |
A sequential tape monitor for toluene diisocyanate.
Topics: Air Pollutants, Occupational; Cyanates; Industry; Polyurethanes; Toluene 2,4-Diisocyanate | 1987 |
Toluene diisocyanate exposures in the flexible polyurethane foam industry.
Topics: Air Pollutants, Occupational; Chemical Industry; Chromatography, High Pressure Liquid; Cyanates; Humans; Maximum Allowable Concentration; Polyurethanes; Toluene 2,4-Diisocyanate | 1987 |
Toluene diisocyanate respiratory reactions. I. Reassessment of the problem.
Topics: Adult; Asthma; Cyanates; Humans; Immunoglobulins; Isomerism; Middle Aged; Occupational Diseases; Respiration; Toluene 2,4-Diisocyanate | 1987 |
[A study on the immunologic effects in workers exposed to low levels of toluene-diisocyanate (TDI)].
Topics: Adult; Air Pollutants, Occupational; Blood Chemical Analysis; Cyanates; Environmental Exposure; Environmental Monitoring; Humans; Immunoglobulins; Middle Aged; Muramidase; Radioallergosorbent Test; Toluene 2,4-Diisocyanate | 1987 |
Specific IgE antibodies in twenty-eight workers with diisocyanate-induced bronchial asthma.
Topics: Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Isocyanates; Male; Occupational Diseases; Toluene 2,4-Diisocyanate | 1984 |
Follow-up study of patients with respiratory disease due to toluene diisocyanate (TDI).
Topics: Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Male; Middle Aged; Occupational Diseases; Respiratory Function Tests; Skin Tests; Time Factors; Toluene 2,4-Diisocyanate | 1984 |
[Hypersensitivity pneumonitis in a polyurethane paint sprayer].
Topics: Alveolitis, Extrinsic Allergic; Cyanates; Female; Humans; Lung; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate | 1984 |
Two-year observation of pulmonary function in workers exposed to low concentrations of toluene diisocyanate.
Topics: Adult; Cross-Sectional Studies; Cyanates; Follow-Up Studies; Humans; Lung; Male; Occupational Diseases; Respiratory Function Tests; Time Factors; Toluene 2,4-Diisocyanate | 1984 |
Specific bronchial provocation tests in occupational asthma and methods of stimulation: case report.
Topics: Asthma; Bronchial Provocation Tests; Cyanates; Occupational Diseases; Paint; Respiratory Function Tests; Toluene 2,4-Diisocyanate | 1983 |
Isocyanate-induced asthma in a car factory.
Topics: Asthma; Automobiles; Cyanates; Female; Humans; Immunoglobulin E; Occupational Diseases; Occupations; Respiratory Function Tests; Toluene 2,4-Diisocyanate | 1980 |
Preparation of covalently linked immune complexes of specific composition.
Topics: Animals; Antigen-Antibody Complex; Cattle; Chromatography, Agarose; Cross-Linking Reagents; Cyanates; gamma-Globulins; Goats; Immune Complex Diseases; Molecular Weight; Rabbits; Serum Albumin, Bovine; Toluene 2,4-Diisocyanate | 1980 |
Study of guinea pig and human antibodies to toluene diisocyanate.
Topics: Animals; Antibodies; Antigens; Cyanates; Epitopes; Guinea Pigs; Humans; Immunosorbent Techniques; Reference Standards; Toluene 2,4-Diisocyanate | 1980 |
[Toluene-diisocyanate-induced asthma. 2. Histamine liberation test using leukocytes from toluene-diisocyanate sensitized guinea pigs].
Topics: Animals; Asthma; Cyanates; Female; Guinea Pigs; Histamine Release; Leukocytes; Toluene 2,4-Diisocyanate | 1983 |
[Nasal allergy observed in an asthma model by toluene diisocyanate (TDI)].
Topics: Animals; Asthma; Cyanates; Disease Models, Animal; Guinea Pigs; Histamine Release; Rhinitis, Allergic, Perennial; Toluene 2,4-Diisocyanate | 1984 |
Isocyanato urethane methacrylates derived from hydroxyethyl methacrylate.
Topics: Acrylates; Chemical Phenomena; Chemistry; Cyanates; Cyanoacrylates; Methacrylates; Spectrophotometry, Infrared; Toluene 2,4-Diisocyanate; Urethane | 1980 |
IgE antibodies in TDI workers.
Topics: Antibodies; Cyanates; Humans; Immunoglobulin E; Toluene 2,4-Diisocyanate | 1980 |
Antigens which detect IgE antibodies in workers sensitive to toluene diisocyanate.
Topics: Antigen-Antibody Reactions; Binding Sites, Antibody; Cyanates; Humans; Immunoglobulin E; Radioallergosorbent Test; Respiratory Hypersensitivity; Serum Albumin; Toluene; Toluene 2,4-Diisocyanate | 1980 |
Immunoglobulin E-mediated asthma and hypersensitivity pneumonitis with precipitating anti-hapten antibodies due to diphenylmethane diisocyanate (MDI) exposure.
Topics: Adult; Alveolitis, Extrinsic Allergic; Antibodies; Asthma; Benzhydryl Compounds; Cross Reactions; Cyanates; Haptens; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Male; Middle Aged; Serum Albumin; Toluene 2,4-Diisocyanate | 1980 |
Absence of airway hyperreactivity to methacholine in a worker sensitized to toluene diisocyanate (TDI).
Topics: Adult; Airway Obstruction; Asthma; Bronchi; Cyanates; Dose-Response Relationship, Drug; Female; Humans; Methacholine Compounds; Occupational Diseases; Toluene 2,4-Diisocyanate | 1980 |
Differences of opinion over TDI.
Topics: Cyanates; Forced Expiratory Volume; Humans; Lung Diseases; Occupational Diseases; Toluene 2,4-Diisocyanate | 1980 |
Immunologic sensitization and pulmonary hypersensitivity by repeated inhalation of aromatic isocyanates.
Topics: Animals; Cyanates; Drug Hypersensitivity; Female; Gases; Guinea Pigs; Immunodiffusion; Immunoelectrophoresis; Isocyanates; Passive Cutaneous Anaphylaxis; Respiration; Respiratory Hypersensitivity; Time Factors; Toluene 2,4-Diisocyanate | 1980 |
Dynamic calibration of a continuous organo-isocyanate monitor for hexamethylene diisocyanate.
Topics: Calibration; Chromatography, High Pressure Liquid; Cyanates; Equipment and Supplies; Isocyanates; Reference Standards; Toluene 2,4-Diisocyanate | 1980 |
Cross-linking preserves conformational changes induced in penicillinase by its substrates.
Topics: beta-Lactamases; Cephalothin; Cloxacillin; Cross-Linking Reagents; Cyanates; Drug Stability; Hot Temperature; Oxacillin; Penicillinase; Protein Conformation; Toluene 2,4-Diisocyanate; Urea | 1980 |
Respiratory function study of Nigerian workers in a TDI-based foam plant.
Topics: Adult; Cyanates; Humans; Lung Diseases; Male; Nigeria; Occupational Diseases; Respiratory Function Tests; Smoking; Time Factors; Toluene 2,4-Diisocyanate | 1980 |
Radioallergosorbent testing of toluene diisocyanate-reactive individuals using p-tolyl isocyanate antigen.
Topics: Antigens; Bronchial Provocation Tests; Cyanates; Drug Hypersensitivity; Humans; Radioallergosorbent Test; Serum Albumin; Toluene 2,4-Diisocyanate | 1980 |
Work-related asthma comes out of hiding.
Topics: Allergens; Asthma; Cyanates; Molecular Weight; Occupational Diseases; Phthalic Anhydrides; Radioallergosorbent Test; Toluene 2,4-Diisocyanate | 1980 |
Contact sensitivity in mice induced by tolylene diisocyanate (TDI).
Topics: Animals; Benzhydryl Compounds; Cross Reactions; Cyanates; Dermatitis, Contact; Humans; Isocyanates; Mice; Mice, Inbred C3H; Thymectomy; Toluene 2,4-Diisocyanate | 1980 |
Pulmonary function of control and industrially exposed Nigerians in asbestos, textile, and toluene diisocyanate-foam factories.
Topics: Adult; Air Pollutants, Occupational; Asbestos; Cyanates; Dust; Forced Expiratory Volume; Gossypium; Humans; Lung; Male; Nigeria; Toluene 2,4-Diisocyanate; Vital Capacity | 1980 |
Experimental studies on TDI dermatitis in mice.
Topics: Animals; Body Weight; Cyanates; Dermatitis, Contact; Dermatitis, Occupational; Ear; Edema; Male; Mice; Organ Size; Skin; T-Lymphocytes; Thymus Gland; Toluene 2,4-Diisocyanate | 1980 |
Simultaneous determination of 2,4- and 2,6-diisocyanatotoluene (TDI) and 3,3'-dichloro-4,4'-diaminodiphenylmethane (MOCA) in air.
Topics: Air; Benzhydryl Compounds; Cyanates; Methylenebis(chloroaniline); Toluene 2,4-Diisocyanate | 1980 |
Toxic corneal epithelial edema from exposure to high atmospheric concentration of toluene diisocyanates.
Topics: Adult; Conjunctival Diseases; Cornea; Corneal Diseases; Cyanates; Edema; Epithelium; Female; Humans; Male; Middle Aged; Occupational Diseases; Polyurethanes; Temperature; Time Factors; Toluene 2,4-Diisocyanate; Ventilation; Visual Acuity | 1980 |
Critical evaluation of continuous monitors for toluene diisocyanate.
Topics: Air Pollutants; Air Pollutants, Occupational; Cyanates; Equipment and Supplies; Humidity; Toluene 2,4-Diisocyanate | 1980 |
More on isocyanate sensitization.
Topics: Air Pollutants; Air Pollutants, Occupational; Cyanates; Humans; Toluene 2,4-Diisocyanate | 1980 |
[Field study with specific Radioallergosorbent Test (RAST) in isocyanate exposed persons].
Topics: Adult; Cyanates; Environmental Exposure; Germany, West; Humans; Middle Aged; Radioallergosorbent Test; Radioimmunoassay; Toluene 2,4-Diisocyanate | 1980 |
[Clinical symptoms and results of RAST and inhalation provocation tests].
Topics: Adult; Cyanates; Humans; Middle Aged; Occupational Diseases; Radioallergosorbent Test; Radioimmunoassay; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 1980 |
Toluene-diisocyanate induced asthma: evaluation of antibodies in the serum of affected workers against a tolyl mono-isocyanate protein conjugate.
Topics: Antibody Formation; Antibody Specificity; Asthma; Cyanates; Humans; Immunoglobulin E; Isocyanates; Occupational Diseases; Radioimmunoassay; Serum Albumin; Toluene 2,4-Diisocyanate | 1981 |
[Occupational asthma (author's transl)].
Topics: Airway Resistance; Asthma; Bronchial Provocation Tests; Cyanates; Humans; Occupational Diseases; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 1980 |
Dermal contact with toluene diisocyanate (TDI) produces respiratory tract hypersensitivity in guinea pigs.
Topics: Administration, Topical; Animals; Antibody Formation; Cyanates; Dermatitis, Contact; Female; Guinea Pigs; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 1981 |
Isocyanate-induced abnormality of beta-adrenergic receptor function.
Topics: Adenylyl Cyclases; Animals; Cyanates; Erythrocyte Membrane; Isocyanates; Isoproterenol; Rana pipiens; Receptors, Adrenergic; Receptors, Adrenergic, beta; Toluene 2,4-Diisocyanate | 1981 |
Specific IgE antibodies in patients with isocyanate asthma.
Topics: Antibodies; Asthma; Benzhydryl Compounds; Cyanates; Humans; Immunoglobulin E; Isocyanates; Toluene 2,4-Diisocyanate | 1981 |
Diverse profiles of immunoreactivity in toluene diisocyanate (TDI) asthma.
Topics: Adult; Antigen-Antibody Reactions; Asthma; Cell Migration Inhibition; Cyanates; Female; Humans; Immunity, Cellular; Lymphokines; Male; Middle Aged; Occupational Diseases; Radioallergosorbent Test; Skin Tests; Toluene 2,4-Diisocyanate | 1981 |
Survey of industrial workers for antibodies to toluene diisocyanate.
Topics: Antibody Formation; Cyanates; Drug Hypersensitivity; Humans; Immunoglobulin E; Occupational Diseases; Respiratory Distress Syndrome; Toluene 2,4-Diisocyanate | 1981 |
[Cardiovascular system changes in workers in toluene diisocyanate manufacture].
Topics: Adult; Cardiovascular System; Conjunctiva; Cyanates; Electrocardiography; Female; Humans; Male; Microcirculation; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate | 1982 |
Warfarin binding to plasma of workers exposed to toluene diisocyanate.
Topics: Adult; Blood Proteins; Chemical Industry; Cyanates; Humans; Occupational Diseases; Protein Binding; Rubber; Toluene 2,4-Diisocyanate; Warfarin | 1982 |
Occupational asthma.
Topics: Animals; Asthma; Bronchi; Cyanates; Dogs; Humans; Isocyanates; Occupational Diseases; Radioallergosorbent Test; Toluene 2,4-Diisocyanate | 1982 |
Inhibition of cholinesterase activity by isocyanates.
Topics: Cholinesterase Inhibitors; Cholinesterases; Cyanates; Humans; Isocyanates; Toluene 2,4-Diisocyanate | 1982 |
Specific inhibition of contact sensitivity in the guinea pig following tolylene diisocyanate inhalation.
Topics: Administration, Intranasal; Administration, Oral; Animals; Cyanates; Cyclophosphamide; Dermatitis, Contact; Dinitrochlorobenzene; Guinea Pigs; Haptens; Immunity; Male; Skin Tests; Toluene 2,4-Diisocyanate | 1982 |
Development and loss of toluene diisocyanate reactivity: immunologic, pharmacologic, and provocative challenge studies.
Topics: Adult; Bronchial Provocation Tests; Cyanates; Humans; Isocyanates; Lymphocyte Activation; Male; Methacholine Compounds; Plants, Edible; Radioallergosorbent Test; Respiratory Function Tests; Respiratory Hypersensitivity; Serum Albumin; Skin Tests; Toluene 2,4-Diisocyanate | 1982 |
Studies on antigens useful for detection of IgE antibodies in isocyanate-sensitized workers.
Topics: Antibodies; Antigens; Cyanates; Humans; Immunoglobulin E; Immunosorbent Techniques; Lung Diseases, Obstructive; Serum Albumin; Spectrophotometry, Ultraviolet; Toluene 2,4-Diisocyanate | 1982 |
Five-year longitudinal study of workers employed in a new toluene diisocyanate manufacturing plant.
Topics: Adult; Chemical Industry; Cyanates; Forced Expiratory Volume; Humans; Longitudinal Studies; Louisiana; Lung Diseases; Lung Volume Measurements; Male; Maximum Allowable Concentration; Occupational Diseases; Risk; Smoking; Spirometry; Toluene 2,4-Diisocyanate | 1982 |
The guinea pig model of diisocyanate sensitization. I. Immunologic studies.
Topics: Animals; Asthma; Cross Reactions; Cyanates; Disease Models, Animal; Female; Guinea Pigs; Humans; Immunization; Immunodiffusion; Immunoelectrophoresis; Immunoglobulin E; Immunoglobulin G; Isocyanates; Occupational Diseases; Passive Cutaneous Anaphylaxis; Serum Albumin; Toluene 2,4-Diisocyanate; Transferrin | 1982 |
The guinea pig model of diisocyanate sensitization. II. Physiologic studies.
Topics: Animals; Asthma; Cyanates; Disease Models, Animal; Female; Guinea Pigs; Immune Sera; Immunoglobulin E; Isocyanates; Occupational Diseases; Respiratory Function Tests; Toluene 2,4-Diisocyanate; Transferrin | 1982 |
Isocyanates represent a serious health hazard.
Topics: Animals; Cyanates; Isocyanates; Toluene 2,4-Diisocyanate | 1982 |
Sensory irritation, pulmonary irritation, and acute lethality of a polymeric isocyanate and sensory irritation of 2,6-toleune diisocyanate.
Topics: Aerosols; Animals; Cyanates; Irritants; Isocyanates; Lethal Dose 50; Lung Diseases; Male; Mice; Time Factors; Toluene 2,4-Diisocyanate | 1982 |
Occupational asthma.
Topics: Asthma; Cyanates; Humans; Male; Middle Aged; Occupational Diseases; Pneumoconiosis; Toluene 2,4-Diisocyanate | 1982 |
Accelerated loss of FEV- in polyurethane production workers: a four-year prospective study.
Topics: Cyanates; Dose-Response Relationship, Drug; Forced Expiratory Volume; Humans; Occupational Diseases; Prospective Studies; Regression Analysis; Smoking; Toluene 2,4-Diisocyanate | 1982 |
Determination of airborne 2,4-toluenediisocyanate vapors.
Topics: Air; Air Pollutants; Air Pollutants, Occupational; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cyanates; Toluene 2,4-Diisocyanate | 1982 |
Absence of respiratory effects in subjects exposed to low concentrations of TDI and MDI.
Topics: Air Pollutants; Air Pollutants, Occupational; Cyanates; Female; Humans; Isocyanates; Lung; Male; Maximal Expiratory Flow Rate; Smoking; Time Factors; Toluene 2,4-Diisocyanate | 1982 |
[On the induction of asthma in guinea pigs by toluene diisocyanate (TDI)].
Topics: Animals; Asthma; Cyanates; Disease Models, Animal; Guinea Pigs; Toluene 2,4-Diisocyanate | 1982 |
Immunologic cross-reactivity between different albumin-bound isocyanates.
Topics: Adult; Aerosols; Asthma; Cyanates; Drug Hypersensitivity; Humans; Isocyanates; Middle Aged; Occupational Diseases; Radioallergosorbent Test; Serum Albumin; Skin Tests; Toluene 2,4-Diisocyanate | 1983 |
Chemical interference effects in the measurement of atmospheric toluene diisocyanate concentrations when sampling with an impregnated paper tape.
Topics: Air Pollutants; Air Pollutants, Occupational; Chemical Phenomena; Chemistry; Cyanates; Indicators and Reagents; Phenylenediamines; Reagent Strips; Toluene 2,4-Diisocyanate | 1982 |
Isocyanate induced asthma.
Topics: Asthma; Bronchial Provocation Tests; Cyanates; Forced Expiratory Volume; Humans; Isocyanates; Occupational Diseases; Toluene 2,4-Diisocyanate | 1982 |
Mechanisms of isocyanate induced asthma.
Topics: Asthma; Cyanates; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Immunoglobulin E; Lymphocytes; Occupational Diseases; Radioimmunoassay; Skin Tests; Toluene 2,4-Diisocyanate | 1982 |
Long-term respiratory effects of isocyanate exposure.
Topics: Cyanates; Dose-Response Relationship, Drug; Environmental Exposure; Forced Expiratory Volume; Humans; Lung; Toluene 2,4-Diisocyanate | 1982 |
Non-specific bronchial hyper-reactivity in workers exposed to toluene di-isocyanate, diphenyl methane di-isocyanate and colophony.
Topics: Asthma; Bronchi; Cyanates; Electronics; Environmental Exposure; Histamine; Humans; Isocyanates; Occupational Diseases; Resins, Plant; Toluene 2,4-Diisocyanate | 1982 |
Radioallergosorbent testing with p-tolyl monoisocyanate in toluene diisocyanate workers.
Topics: Asthma; Cyanates; Dermatitis, Atopic; Drug Hypersensitivity; False Positive Reactions; Humans; Immunoglobulin E; Isocyanates; Occupational Diseases; Radioallergosorbent Test; Toluene 2,4-Diisocyanate | 1983 |
Absence of IgG antibodies to TDI-HSA in a radioimmunological study.
Topics: Animals; Asthma; Cyanates; Humans; Immunoglobulin G; Occupational Diseases; Rabbits; Radioimmunoassay; Respiratory Hypersensitivity; Serum Albumin; Toluene 2,4-Diisocyanate | 1983 |
Long-term toxicity and carcinogenicity studies with 2,4/2,6-toluene-diisocyanate (80/20) in rats and mice.
Topics: Animals; Carcinogens; Cell Nucleus; Cyanates; Female; Gases; Isomerism; Male; Mice; Neoplasms, Experimental; Organ Size; Rats; Rats, Inbred F344; Rats, Inbred Strains; Species Specificity; Toluene 2,4-Diisocyanate | 1983 |
Concentration-dependent elicitation of dermal sensitization in guinea pigs treated with 2,4-toluene diisocyanate.
Topics: Animals; Cyanates; Dermatitis, Contact; Dose-Response Relationship, Drug; Guinea Pigs; Toluene 2,4-Diisocyanate | 1983 |
A gas chromatographic procedure for the determination of airborne MDI and TDI.
Topics: Air; Air Pollutants; Chromatography, Gas; Cyanates; Isocyanates; Toluene 2,4-Diisocyanate | 1983 |
[Asthma induced by diphenylmethane diisocyanate].
Topics: Adult; Asthma; Chemical Phenomena; Chemistry; Cyanates; Humans; Isocyanates; Male; Middle Aged; Occupational Diseases; Risk; Toluene 2,4-Diisocyanate | 1983 |
Immunologic and respiratory responses to airway challenges of dogs with toluene diisocyanate.
Topics: Animals; Antibody Formation; Asthma; Bronchial Provocation Tests; Cyanates; Dogs; Forced Expiratory Flow Rates; Hypersensitivity, Immediate; Immunoglobulin A; Immunoglobulin E; Immunoglobulin G; Immunoglobulin M; Lymphocyte Activation; Tidal Volume; Toluene 2,4-Diisocyanate | 1983 |
Concentration-dependent immunologic response to toluene diisocyanate (TDI) following inhalation exposure.
Topics: Animals; Antibody Formation; Atmosphere Exposure Chambers; Bronchial Provocation Tests; Cyanates; Dose-Response Relationship, Drug; Female; Guinea Pigs; Immunization; Intradermal Tests; Lung; Passive Cutaneous Anaphylaxis; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 1983 |
Effect of toluene diisocyanate on beta adrenergic receptor function. Biochemical and physiologic studies.
Topics: Adenylyl Cyclases; Animals; Cyanates; Erythrocyte Membrane; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth; Rana pipiens; Receptors, Adrenergic; Receptors, Adrenergic, beta; Toluene 2,4-Diisocyanate; Trachea | 1983 |
Five-year longitudinal study of workers employed in a new toluene diisocyanate manufacturing plant.
Topics: Cyanates; Humans; Longitudinal Studies; Maximum Allowable Concentration; Occupational Diseases; Toluene 2,4-Diisocyanate; United States | 1983 |
[Toluene diisocyanate asthma. 1. Clinico-immunological evaluation].
Topics: Adult; Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Immunoglobulin E; Male; Occupational Diseases; Radioallergosorbent Test; Toluene 2,4-Diisocyanate | 1983 |
Immobilization of antibody to a plastic surface by toluene 2,4-diisocyanate and its application to radioimmunoassay.
Topics: Antibodies; Cyanates; Glutaral; Immune Sera; Immunoglobulin G; Polypropylenes; Polystyrenes; Prolactin; Radioimmunoassay; Thyrotropin; Toluene 2,4-Diisocyanate | 1983 |
Inhibition of acetylcholinesterase by diisocyanates and its spontaneous reactivation.
Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Cyanates; Dose-Response Relationship, Drug; Environmental Exposure; Erythrocytes; Humans; In Vitro Techniques; Isocyanates; Risk; Software; Toluene 2,4-Diisocyanate | 1983 |
Antibodies against toluene diisocyanate protein conjugates. Three methods of measurement.
Topics: Ammonium Sulfate; Animals; Antibodies; Chemical Precipitation; Cyanates; Dogs; Enzyme-Linked Immunosorbent Assay; Immunization; Methods; Time Factors; Toluene 2,4-Diisocyanate | 1983 |
Experimental model of asthma by toluene diisocyanate (TDI).
Topics: Animals; Asthma; Cyanates; Disease Models, Animal; Female; Guinea Pigs; Lung; Male; Occupational Diseases; Toluene 2,4-Diisocyanate | 1983 |
Hyperreactive airway smooth muscle responsiveness after inhalation of toluene diisocyanate vapors.
Topics: Animals; Carbachol; Cyanates; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Toluene 2,4-Diisocyanate; Trachea | 1984 |
Health hazard by exposure to toluene-diisocyanate in the shipyard.
Topics: Air Pollutants, Occupational; Cyanates; Environmental Exposure; Humans; Immunoglobulin E; Leukocyte Count; Male; Respiratory Function Tests; Ships; Toluene 2,4-Diisocyanate | 1984 |
Carcinogenesis results on seven amines, two phenols, and one diisocyanate used in plastics and synthetic elastomers.
Topics: Amines; Animals; Carcinogens; Chemical Industry; Cyanates; Female; Male; Mice; Mice, Inbred Strains; Phenols; Plastics; Rats; Rats, Inbred F344; Rubber; Toluene 2,4-Diisocyanate | 1984 |
Isomeric composition of airborne TDI in the polyurethane foam industry.
Topics: Air Pollutants, Occupational; Chemical Industry; Chromatography, High Pressure Liquid; Cyanates; Humans; Isomerism; Maximum Allowable Concentration; Polyurethanes; Toluene 2,4-Diisocyanate | 1984 |
[Biogenic amines and immunoglobulins in workers occupationally exposed to chemical and biological allergens].
Topics: Adult; Cyanates; Dysgammaglobulinemia; Histamine; Humans; Hypergammaglobulinemia; Immunoglobulins; Occupational Medicine; Serotonin; Toluene 2,4-Diisocyanate; Yeast, Dried | 1984 |
Respiratory variables and exposure-effect relationships in isocyanate-exposed workers.
Topics: Adult; Air Pollutants, Occupational; Cough; Cyanates; Dyspnea; Female; Humans; Male; Middle Aged; Occupational Diseases; Respiratory Function Tests; Time Factors; Toluene 2,4-Diisocyanate | 1984 |
Antigen-specific stimulation of histamine releasing factors in diisocyanate-induced occupational asthma.
Topics: Allergens; Antibody Specificity; Asthma; Biomarkers; Biomarkers, Tumor; Cells, Cultured; Dose-Response Relationship, Immunologic; Epitopes; Female; Histamine Release; Humans; Isocyanates; Leukocytes, Mononuclear; Lymphokines; Male; Occupational Diseases; Statistics, Nonparametric; Toluene 2,4-Diisocyanate; Tumor Protein, Translationally-Controlled 1 | 1994 |
[Induction of rat liver foci by inhaled diisocyanate exposure].
Topics: Air Pollutants, Occupational; Animals; Carcinogenicity Tests; Cell Transformation, Neoplastic; Cyanates; Dose-Response Relationship, Drug; Female; Isocyanates; Liver; Liver Neoplasms, Experimental; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Toluene 2,4-Diisocyanate | 1995 |
Investigation of the ability of MDHS method 25 to determine urethane-bound isocyanate groups.
Topics: Chromatography, High Pressure Liquid; Electrochemistry; Ethylene Glycol; Ethylene Glycols; Hazardous Substances; Isocyanates; Polyurethanes; Reproducibility of Results; Spectrophotometry, Ultraviolet; Toluene 2,4-Diisocyanate | 1995 |
A two-centre study for the evaluation and validation of an animal model for the assessment of the potential of small molecular weight chemicals to cause respiratory allergy.
Topics: Administration, Inhalation; Allergens; Animals; Antibody Specificity; Antigen-Antibody Complex; Dinitrochlorobenzene; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Guinea Pigs; Haptens; Injections, Intradermal; Isocyanates; Male; Molecular Weight; Phthalic Anhydrides; Respiration; Respiratory Hypersensitivity; Serum Albumin; Toluene 2,4-Diisocyanate | 1995 |
Biocompatible polyurethane-based hydrogel.
Topics: Adsorption; Animals; Antigens; Biocompatible Materials; Contact Lenses; Gels; Growth Substances; Half-Life; Hydrogel, Polyethylene Glycol Dimethacrylate; Isocyanates; Materials Testing; Polyethylene Glycols; Polyethylenes; Polypropylenes; Polyurethanes; Proteins; Silicon Dioxide; Solubility; Surface Properties; Surface-Active Agents; Toluene 2,4-Diisocyanate | 1994 |
Sputum eosinophilia after asthmatic responses induced by isocyanates in sensitized subjects.
Topics: Adult; Aerosols; Asthma; Bronchial Hyperreactivity; Eosinophilia; Female; Humans; Isocyanates; Leukocyte Count; Male; Occupational Diseases; Sputum; Toluene 2,4-Diisocyanate | 1994 |
Incidence of cancer and exposure to toluene diisocyanate and methylene diphenyldiisocyanate: a cohort based case-referent study in the polyurethane foam manufacturing industry.
Topics: Case-Control Studies; Cohort Studies; Humans; Incidence; Isocyanates; Male; Neoplasms; Occupational Diseases; Occupational Exposure; Polyurethanes; Prostatic Neoplasms; Sweden; Toluene 2,4-Diisocyanate | 1993 |
Increased incidence of anti-dsDNA autoantibody concentration in sera of workers occupationally exposed to diisocyanates.
Topics: Adult; Antibodies, Anti-Idiotypic; Antibodies, Antinuclear; Autoantibodies; Cyanates; DNA; Humans; Isocyanates; Male; Middle Aged; Occupational Exposure; Toluene 2,4-Diisocyanate | 1993 |
Cancer incidence and mortality in the Swedish polyurethane foam manufacturing industry.
Topics: Adult; Aged; Cause of Death; Chemical Industry; Cohort Studies; Cyanates; Female; Humans; Incidence; Isocyanates; Male; Middle Aged; Neoplasms; Occupational Diseases; Occupational Exposure; Sweden; Time Factors; Toluene 2,4-Diisocyanate | 1993 |
Phenyl isocyanate is a potent chemical sensitizer.
Topics: Animals; Antibody Formation; Asthma; Cyanates; Dermatitis, Contact; Ear, External; Immunity, Cellular; Immunoglobulin E; Isocyanates; Mice; Mice, Inbred BALB C; Toluene 2,4-Diisocyanate | 1996 |
Comparison of the binding potential of various diisocyanates on DNA in vitro.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry, Physical; Cyanates; DNA; Isocyanates; Nucleic Acid Conformation; Nucleic Acid Denaturation; Toluene 2,4-Diisocyanate | 1997 |
Diisocyanate antigen-enhanced production of monocyte chemoattractant protein-1, IL-8, and tumor necrosis factor-alpha by peripheral mononuclear cells of workers with occupational asthma.
Topics: Adult; Antigens; Asthma; Biomarkers, Tumor; Chemokine CCL2; Chemokines; Cyanates; Female; Humans; Interleukin-8; Isocyanates; Leukocytes, Mononuclear; Lymphokines; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha; Tumor Protein, Translationally-Controlled 1 | 1998 |
Chemical behaviour of seven aromatic diisocyanates (toluenediisocyanates and diphenylmethanediisocyanates) under in vitro conditions in relationship to their results in the Salmonella/microsome test.
Topics: Animals; Drug Stability; Isocyanates; Male; Microsomes, Liver; Mutagenicity Tests; Rats; Rats, Sprague-Dawley; Toluene 2,4-Diisocyanate | 1999 |
2,4-toluenediisocyanate and hexamethylene-diisocyanate adducts with blood proteins: assessment of reactivity of amino acid residues in vitro.
Topics: Albumins; Amino Acids; Blood Proteins; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cyanates; Globins; In Vitro Techniques; Isocyanates; Toluene 2,4-Diisocyanate | 1999 |
Subchronic exposure to diisocyanates increases guinea pig tracheal smooth muscle responses to acetylcholine.
Topics: Acetylcholine; Animals; Culture Techniques; Cyanates; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Guinea Pigs; Isocyanates; Lung Diseases; Muscle Contraction; Muscle, Smooth; Reference Values; Toluene 2,4-Diisocyanate; Trachea | 1999 |
Specific IgG response to monomeric and polymeric diphenylmethane diisocyanate conjugates in subjects with respiratory reactions to isocyanates.
Topics: Adult; Allergens; Antibody Specificity; Asthma; Cross Reactions; Female; Forced Expiratory Volume; Humans; Immunoglobulin G; Isocyanates; Male; Middle Aged; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 1999 |
Increase in airway hyperresponsiveness among workers exposed to methylene diphenyldiisocyanate compared to workers exposed to toluene diisocyanate at a petrochemical plant in Korea.
Topics: Adult; Air Pollutants, Occupational; Allergens; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chemical Industry; Female; Forced Expiratory Volume; Humans; Intradermal Tests; Isocyanates; Korea; Male; Occupational Diseases; Petroleum; Toluene 2,4-Diisocyanate | 2000 |
Long-term follow-up of hexamethylene diisocyanate-, diphenylmethane diisocyanate-, and toluene diisocyanate-induced asthma.
Topics: Adult; Air Pollutants; Allergens; Asthma; Cyanates; Female; Follow-Up Studies; Humans; Immunoglobulin E; Isocyanates; Male; Surveys and Questionnaires; Toluene 2,4-Diisocyanate | 2000 |
Isocyanate exposure and occupational asthma: a case-referent study.
Topics: Adolescent; Adult; Allergens; Asthma; Case-Control Studies; Female; Humans; Hypersensitivity, Immediate; Isocyanates; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Risk Factors; Smoking; Toluene 2,4-Diisocyanate | 2000 |
Asthma from diisocyanates is not mediated through a Type IV, patch-test-positive mechanism.
Topics: Adult; Allergens; Asthma; Dermatitis, Allergic Contact; Dermatitis, Occupational; Female; Hand Dermatoses; Humans; Isocyanates; Male; Middle Aged; Paint; Patch Tests; Toluene 2,4-Diisocyanate | 2001 |
Mechanisms of isocyanate sensitisation. An in vitro approach.
Topics: Cyanates; Flow Cytometry; Humans; Intercellular Adhesion Molecule-1; Isocyanates; Monocytes; Peroxides; Respiratory Burst; Toluene 2,4-Diisocyanate; Tumor Cells, Cultured | 2001 |
Assessment of preferential Th1 or Th2 induction by low-molecular-weight compounds using a reverse transcription-polymerase chain reaction method: comparison of two mouse strains, C57BL/6 and BALB/c.
Topics: Allergens; Animals; Dinitrochlorobenzene; Dinitrofluorobenzene; DNA Primers; Interleukin-12; Interleukin-4; Isocyanates; Local Lymph Node Assay; Lymph Nodes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Molecular Weight; Oxazoles; Phthalic Anhydrides; Picryl Chloride; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Species Specificity; Th1 Cells; Th2 Cells; Toluene 2,4-Diisocyanate | 2001 |
Spectroscopic anatomy of molecular-imprinting of cyclodextrin. Evidence for preferential formation of ordered cyclodextrin assemblies.
Topics: beta-Cyclodextrins; Cholesterol; Cross-Linking Reagents; Cyanates; Cyclodextrins; Isocyanates; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stigmasterol; Templates, Genetic; Toluene 2,4-Diisocyanate | 2002 |
Fate and potential environmental effects of methylenediphenyl diisocyanate and toluene diisocyanate released into the atmosphere.
Topics: Aerosols; Air Pollutants; Atmosphere; Environmental Monitoring; Forecasting; Humans; Isocyanates; Oxidation-Reduction; Toluene 2,4-Diisocyanate; Water | 2003 |
Need for monitoring nonspecific bronchial hyperresponsiveness before and after isocyanate inhalation challenge.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cyanates; False Negative Reactions; Female; Forced Expiratory Volume; Humans; Isocyanates; Male; Middle Aged; Monitoring, Physiologic; Occupational Diseases; Prospective Studies; Toluene 2,4-Diisocyanate | 2003 |
Effects of thermal degradation products from polyurethane foams based on toluene diisocyanate and diphenylmethane diisocyanate on isolated, perfused lung of guinea pig.
Topics: Aerosols; Air Pollutants, Occupational; Animals; Chemical Industry; Disease Models, Animal; Environmental Monitoring; Female; Guinea Pigs; Hot Temperature; Isocyanates; Lung; Male; Perfusion; Polyurethanes; Probability; Risk Assessment; Toluene 2,4-Diisocyanate | 2003 |
Toluene diisocyanate; engineering and medical control of exposures in polyurethane foam manufacturing.
Topics: Cyanates; Engineering; Humans; Occupational Diseases; Polyurethanes; Toluene; Toluene 2,4-Diisocyanate | 1957 |
Industrial hygiene experiences with toluene diisocyanate.
Topics: Cyanates; Humans; Occupational Health; Toluene; Toluene 2,4-Diisocyanate | 1959 |
[On the toxicology of toluene diisocyanate].
Topics: Cyanates; Humans; Toluene; Toluene 2,4-Diisocyanate | 1962 |
Thrombocytopenic purpura in toluene di-isocyanate workers.
Topics: Cyanates; Humans; Occupational Diseases; Purpura, Thrombocytopenic; Toluene; Toluene 2,4-Diisocyanate | 1963 |
TOLUENE DIISOCYANATE ASTHMA. REVIEW AND CASE REPORT WITH RESPONSE TO STEROIDS.
Topics: Asthma; Bronchial Spasm; Cyanates; Humans; Occupational Diseases; Respiratory Function Tests; Steroids; Toluene; Toluene 2,4-Diisocyanate; Toxicology | 1963 |
RESPIRATORY IRRITATION FROM TOLUENE DIISOCYANATE.
Topics: Cyanates; Humans; Occupational Diseases; Paint; Respiratory Function Tests; Respiratory Tract Diseases; Toluene; Toluene 2,4-Diisocyanate; Toxicology | 1964 |
[Observations on workers exposed to 2-4-toluene-diisocyanate (Desmodur T)].
Topics: Cyanates; Humans; Lung Abscess; Occupational Diseases; Toluene; Toluene 2,4-Diisocyanate | 1962 |
Hydrolytic stability of toluene diisocyanate and polymeric methylenediphenyl diisocyanate based polyureas under environmental conditions.
Topics: Allergens; Environmental Monitoring; Environmental Pollutants; Half-Life; Hydrogen-Ion Concentration; Hydrolysis; Isocyanates; Polyurethanes; Temperature; Toluene 2,4-Diisocyanate | 2004 |
Quantitative determination of hexamethylene diisocyanate (HDI), 2,4-toluene diisocyanate (2,4-TDI) and 2,6-toluene diisocyanate (2,6-TDI) monomers at ppt levels in air by alkaline adduct coordination ionspray tandem mass spectrometry.
Topics: Air Pollutants, Occupational; Cyanates; Environmental Monitoring; Humans; Isocyanates; Isomerism; Mass Spectrometry; Sensitivity and Specificity; Specimen Handling; Toluene 2,4-Diisocyanate | 2005 |
DNA strand breaks in the lymphocytes of workers exposed to diisocyanates: indications of individual differences in susceptibility after low-dose and short-term exposure.
Topics: Adult; Air Pollutants, Occupational; Comet Assay; Cyanates; Disease Susceptibility; DNA Damage; Dose-Response Relationship, Drug; Female; Humans; Isocyanates; Lymphocytes; Male; Middle Aged; Occupational Exposure; Time Factors; Toluene 2,4-Diisocyanate | 2005 |
[Diisocyanate exposure as a cause of occupational asthma].
Topics: Adult; Asthma; Cyanates; Humans; Middle Aged; Occupational Diseases; Occupational Exposure; Toluene 2,4-Diisocyanate | 2004 |
Diisocyanates and nonoccupational disease: a review.
Topics: Asthma; Child; Cyanates; Environmental Exposure; Household Products; Humans; Polyurethanes; Toluene 2,4-Diisocyanate | 2004 |
Chemical analysis of 2,4-toluene diisocyanate, 1,6-hexamethylene diisocyanate and isophorone diisocyanate in petrolatum patch-test preparations.
Topics: Cyanates; Humans; Isocyanates; Patch Tests; Petrolatum; Reproducibility of Results; Toluene 2,4-Diisocyanate | 2005 |
Evaluation of antibody binding to diisocyanate protein conjugates in a general population.
Topics: Adolescent; Adult; Antibody Specificity; Cyanates; Environmental Exposure; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin G; Isocyanates; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Prevalence; Toluene 2,4-Diisocyanate | 2006 |
The effect of monomers on the formulation of polymeric nanocapsules based on polyureas and polyamides.
Topics: Alkanes; Chemistry, Pharmaceutical; Crystallization; Cyanates; Diamines; Drug Carriers; Drug Compounding; Emulsions; Ethylenediamines; Isocyanates; Molecular Structure; Nanocapsules; Nylons; Oils; Particle Size; Permeability; Phthalic Acids; Polyamines; Polymers; Technology, Pharmaceutical; Toluene 2,4-Diisocyanate; Water | 2007 |
Eye and airway symptoms in low occupational exposure to toluene diisocyanate.
Topics: Adult; Air Pollutants, Occupational; Biomarkers; Cross-Sectional Studies; Dose-Response Relationship, Immunologic; Eye Diseases; Female; Humans; Isocyanates; Male; Middle Aged; Occupational Exposure; Respiratory Tract Infections; Sweden; Toluene 2,4-Diisocyanate | 2007 |
Active single-drop microextraction for the determination of gaseous diisocyanates.
Topics: Chromatography, High Pressure Liquid; Cyanates; Isocyanates; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Toluene 2,4-Diisocyanate; Water | 2008 |
Contact sensitization to 4,4'-diaminodiphenylmethane and to isocyanates among general dermatology patients.
Topics: Allergens; Cyanates; Dermatitis, Allergic Contact; Dermatitis, Occupational; Female; Finland; Humans; Isocyanates; Male; Patch Tests; Risk Factors; Toluene 2,4-Diisocyanate | 2008 |
Validation of transferability of DBA derivatization and LC-MS/MS determination method for isocyanates via an interlaboratory comparison.
Topics: Air Pollutants, Occupational; Butylamines; Chromatography, Liquid; Environmental Monitoring; Industry; Isocyanates; Laboratories; Occupational Exposure; Paint; Polyurethanes; Tandem Mass Spectrometry; Toluene 2,4-Diisocyanate | 2008 |
Rats repeatedly exposed to toluene diisocyanate exhibit immune reactivity against methyl isocyanate-protein conjugates.
Topics: Administration, Inhalation; Animals; Asthma; Epitopes; Female; Humans; Immunoglobulin G; Isocyanates; Male; Multiprotein Complexes; Neutrophil Infiltration; Occupational Exposure; Rats; Rats, Inbred F344; Rats, Wistar; Respiratory Function Tests; Toluene 2,4-Diisocyanate; Weight Gain | 2009 |
Monoclonal antibodies against toluene diisocyanate haptenated proteins from vapor-exposed mice.
Topics: Administration, Inhalation; Animals; Antibodies, Monoclonal; Antibody Specificity; Asthma; Enzyme-Linked Immunosorbent Assay; Female; Haptens; Humans; Hybridomas; Immunoblotting; Immunoglobulin M; Isocyanates; Mice; Mice, Inbred C57BL; Serum Albumin; Toluene 2,4-Diisocyanate | 2010 |
Dermal uptake and excretion of 14C-toluene diisocyante (TDI) and 14C-methylene diphenyl diisocyanate (MDI) in male rats. Clinical signs and histopathology following dermal exposure of male rats to TDI.
Topics: Animals; Carbon Radioisotopes; Isocyanates; Male; Rats; Rats, Wistar; Skin; Toluene 2,4-Diisocyanate | 2010 |
Micronuclei, hemoglobin adducts and respiratory tract irritation in mice after inhalation of toluene diisocyanate (TDI) and 4,4'-methylenediphenyl diisocyanate (MDI).
Topics: Administration, Inhalation; Aerosols; Animals; Hemoglobins; Isocyanates; Male; Mice; Mice, Inbred C57BL; Micronucleus Tests; Mutagens; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 2011 |
Determination of isocyanate specific albumin-adducts in workers exposed to toluene diisocyanates.
Topics: Adult; Air Pollutants, Occupational; Albumins; Asthma; Biomarkers; Chemical Industry; Chromatography, Liquid; Humans; Isocyanates; Lysine; Mass Spectrometry; Middle Aged; Toluene 2,4-Diisocyanate | 2012 |
Role of vitamin D-binding protein in isocyanate-induced occupational asthma.
Topics: Adult; Animals; Asthma; Cell Line; Epithelial Cells; Female; Gene Expression; Humans; Isocyanates; Male; Middle Aged; Occupational Diseases; Rats; Toluene 2,4-Diisocyanate; Vitamin D-Binding Protein | 2012 |
Occupational contact allergy to monomeric isocyanates.
Topics: Allergens; Aniline Compounds; Cyanates; Dermatitis, Allergic Contact; Dermatitis, Occupational; Female; Humans; Isocyanates; Male; Occupations; Toluene 2,4-Diisocyanate | 2012 |
Genetic variants in antioxidant genes are associated with diisocyanate-induced asthma.
Topics: Adult; Antioxidants; Asthma; Canada; Cyanates; Female; Genetic Predisposition to Disease; Genetic Variation; Humans; Isocyanates; Male; Toluene 2,4-Diisocyanate | 2012 |
Assessment of exposure to TDI and MDI during polyurethane foam production in Poland using integrated theoretical and experimental data.
Topics: Air Pollutants, Occupational; Cyanates; Environmental Monitoring; Humans; Inhalation Exposure; Isocyanates; Models, Theoretical; Occupational Exposure; Poland; Polyurethanes; Toluene 2,4-Diisocyanate | 2012 |
Biomarkers of exposure in Monday morning urine samples as a long-term measure of exposure to aromatic diisocyanates.
Topics: Air Pollutants, Occupational; Biomarkers; Environmental Monitoring; Female; Genotype; Glutathione Transferase; Humans; Isocyanates; Male; Occupational Exposure; Polymorphism, Genetic; Sweden; Toluene 2,4-Diisocyanate | 2014 |
Development of sandwich ELISAs for the detection of aromatic diisocyanate adducts.
Topics: Antibodies, Monoclonal; Enzyme-Linked Immunosorbent Assay; Humans; Isocyanates; Serum Albumin; Toluene 2,4-Diisocyanate | 2013 |
Biocompatibility and cytotoxicity of two novel low-shrinkage dental resin matrices.
Topics: Cell Survival; Cells, Cultured; Humans; Isocyanates; Materials Testing; Reactive Oxygen Species; Resins, Synthetic; Toluene 2,4-Diisocyanate | 2014 |
Characterization of urethane-dimethacrylate derivatives as alternative monomers for the restorative composite matrix.
Topics: Composite Resins; Cyclohexanes; Dental Materials; Dental Restoration, Permanent; Elastic Modulus; Ethylene Glycol; Ethylene Glycols; Hardness; Isocyanates; Light-Curing of Dental Adhesives; Materials Testing; Methacrylates; Nitriles; Pliability; Polyethylene Glycols; Polymerization; Polymethacrylic Acids; Polyurethanes; Surface Properties; Toluene 2,4-Diisocyanate; Transition Temperature; Viscosity; Water | 2014 |
Interfacial thiol-isocyanate reactions for functional nanocarriers: a facile route towards tunable morphologies and hydrophilic payload encapsulation.
Topics: Antibiotics, Antineoplastic; Doxorubicin; Drug Delivery Systems; Emulsions; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; Isocyanates; Nanoparticles; Particle Size; Potassium Chloride; Sulfhydryl Compounds; Toluene 2,4-Diisocyanate; Urethane | 2015 |
Toluene diisocyanate and methylene diphenyl diisocyanate: asthmatic response and cross-reactivity in a mouse model.
Topics: Air Pollutants, Occupational; Animals; Asthma; Cross Reactions; Disease Models, Animal; Immunoglobulin E; Isocyanates; Male; Mice, Inbred C57BL; Th1-Th2 Balance; Toluene 2,4-Diisocyanate | 2016 |
Characterization and comparative analysis of 2,4-toluene diisocyanate and 1,6-hexamethylene diisocyanate haptenated human serum albumin and hemoglobin.
Topics: Cross-Linking Reagents; Enzyme-Linked Immunosorbent Assay; Haptens; Hemoglobins; Humans; Isocyanates; Serum Albumin; Toluene 2,4-Diisocyanate | 2016 |
A novel mouse model of atopic dermatitis that is T helper 2 (Th2)-polarized by an epicutaneous allergen.
Topics: Allergens; Animals; Dermatitis, Atopic; Detergents; Dinitrochlorobenzene; Disease Models, Animal; Female; Formaldehyde; Immunoglobulin E; Interferon-gamma; Interleukin-4; Isocyanates; Mast Cells; Mice, Inbred BALB C; Phthalic Anhydrides; Pyroglyphidae; Skin; Th2 Cells; Toluene; Toluene 2,4-Diisocyanate | 2018 |
Concentration × time analyses of sensory irritants revisited: Weight of evidence or the toxic load approach. That is the question.
Topics: Ammonia; Animals; Dose-Response Relationship, Drug; Inhalation Exposure; Irritants; Isocyanates; Lethal Dose 50; Lung; Lung Diseases; Male; Mice; Models, Theoretical; Phosgene; Rats, Wistar; Respiration; Risk Assessment; Sensory Thresholds; Solubility; Time Factors; Toluene 2,4-Diisocyanate | 2019 |
Development of a method for quantification of toluene diisocyanate and methylenediphenyl diisocyanate migration from polyurethane foam sample surface to artificial sweat by HPLC-UV-MS.
Topics: Air Pollutants, Occupational; Chromatography, High Pressure Liquid; Environmental Exposure; Environmental Monitoring; Humans; Isocyanates; Movement; Paint; Polyurethanes; Surface Properties; Sweat; Tandem Mass Spectrometry; Toluene 2,4-Diisocyanate | 2020 |
Molecular Characterization and Experimental Utility of Monoclonal Antibodies with Specificity for Aliphatic Di- and Polyisocyanates.
Topics: Actins; Albumins; Animals; Antibodies, Monoclonal; Antibody Specificity; Epitopes; Humans; Hybridomas; Isocyanates; Mice; Polyurethanes; Protein Binding; Toluene 2,4-Diisocyanate; Transferrin | 2020 |
Exploring structure/property relationships to health and environmental hazards of polymeric polyisocyanate prepolymer substances-2. Dermal sensitization potential in the mouse local lymph node assay.
Topics: Animals; Isocyanates; Local Lymph Node Assay; Mice; Polyurethanes; Respiratory System; Toluene 2,4-Diisocyanate | 2022 |
Development of a new SPE UPLC-MS/MS method for extraction and quantitation of toluene diamine on gloves following toluene diisocyanate exposure.
Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Gas Chromatography-Mass Spectrometry; Isocyanates; Tandem Mass Spectrometry; Toluene 2,4-Diisocyanate | 2022 |
Isocyanates may contribute to allergic contact dermatitis from diabetes devices and wound dressings.
Topics: Allergens; Amines; Bandages; Dermatitis, Allergic Contact; Diabetes Mellitus; Humans; Isocyanates; Polyurethanes; Toluene 2,4-Diisocyanate | 2022 |
Diisocyanates influence models of atopic dermatitis through direct activation of TRPA1.
Topics: Animals; Cytoskeletal Proteins; Dermatitis, Atopic; Exanthema; Humans; Isocyanates; Mice; Pruritus; Toluene 2,4-Diisocyanate; TRPA1 Cation Channel | 2023 |
A physiologically-based kinetic (PBK) model for work-related diisocyanate exposure: Relevance for the design and reporting of biomonitoring studies.
Topics: Biological Monitoring; Causality; Humans; Isocyanates; Occupational Exposure; Toluene 2,4-Diisocyanate | 2023 |
Sampling chamber with minimal wall surface for simultaneous emission testing of diisocyanates and diamines from polyurethane products.
Topics: Amines; Chromatography, Liquid; Diamines; Isocyanates; Polyurethanes; Tandem Mass Spectrometry; Toluene 2,4-Diisocyanate | 2023 |