tolmetin has been researched along with st 679 in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amico-Roxas, M; Attaguile, G; Caruso, A; Cutuli, VM; De Bernardis, E | 1 |
| Arrigoni Martelli, E; Bruno, G; Cardace, G; Mancinelli, A; Marzo, A; Morabito, E | 1 |
| Annunziato, L; di Renzo, G | 2 |
| Ciarimboli, M; Donati, G; Garzya, G; Imparato, L; Lingetti, M; Nolfe, G; Porfido, FA; Saraceni, G; Sorrentino, GP | 1 |
| Carminati, P; Coppelli, G; Coruzzi, G; Grandi, D; Lo Giudice, P; Longo, A; Morini, G; Pace, S; Pacifici, L; Pisano, C; Vesci, L | 1 |
| Cavestro, GM; Coppelli, G; Coruzzi, G; Lo Giudice, P; Okolicsanyi, L; Pisano, C; Spaggiari, S; Tepperman, BL | 1 |
| Alexandova, A; Kesiova, M; Kirkova, M; Todorov, S | 1 |
| Bharathi, DV; Chatki, P; Hotha, KK; Kumar, SS; Mullangi, R; Ravindranath, LK; Reddy, YN; Veera, KN | 1 |
| Li, X; Liu, D; Rong, Z; Xiang, D; Xu, Y; Zhang, C | 1 |
4 trial(s) available for tolmetin and st 679
| Article | Year |
|---|---|
[A bioequivalence study of tablet and powder formulations of the nonsteroidal anti-inflammatory drug 2-methoxyphenyl 1-methyl-5-(p-methylbenzoylpyrrol)-2-acetamidoacetate].
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Glycine; Humans; Male; Powders; Pyrroles; Tablets; Therapeutic Equivalency; Time Factors; Tolmetin | 1993 |
[An evaluation of the therapeutic activity and tolerance of ST-679 in patients with osteoarthritis at different sites. A controlled double-blind study vs tolmetin].
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Interactions; Drug Tolerance; Female; Glycine; Humans; Italy; Male; Middle Aged; Osteoarthritis; Pyrroles; Time Factors; Tolmetin | 1993 |
[A bioequivalence study in man of tablet and capsule formulations of the nonsteroidal anti-inflammatory compound 2-methoxyphenyl 1-methyl-5-(p-methylbenzoylpyrrol)-2-acetamidoacetate].
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Capsules; Female; Glycine; Humans; Male; Pyrroles; Tablets; Therapeutic Equivalency; Time Factors; Tolmetin | 1993 |
Validation and clinical application of an LC-ESI-MS/MS method for simultaneous determination of tolmetin and MED5, the metabolites of amtolmetin guacil in human plasma.
Topics: Chromatography, Liquid; Drug Stability; Glycine; Humans; Linear Models; Male; Pyrroles; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tolmetin | 2010 |
6 other study(ies) available for tolmetin and st 679
| Article | Year |
|---|---|
Pharmacological properties and toxicology of MED-15, a prodrug of tolmetin.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Glycine; Lethal Dose 50; Male; Peptic Ulcer; Prodrugs; Pyrroles; Rats; Rats, Wistar; Tolmetin | 1992 |
High-performance liquid chromatographic evaluation of Med 15 and its metabolites Med 5 and tolmetin in rat plasma.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Gas; Chromatography, High Pressure Liquid; Glycine; Male; Mass Spectrometry; Pyrroles; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet; Tolmetin | 1991 |
Gastrosparing effect of new antiinflammatory drug amtolmetin guacyl in the rat: involvement of nitric oxide.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Gastric Mucosa; Glycine; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pyrroles; Rats; Rats, Wistar; Tolmetin | 1999 |
Gastroprotective effects of amtolmetin guacyl: a new non-steroidal anti-inflammatory drug that activates inducible gastric nitric oxide synthase.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Ethanol; Gastric Mucosa; Glycine; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase; Peroxidase; Pyrroles; Rats; Rats, Wistar; Tolmetin | 2002 |
In vivo effects of amtolmetin guacyl on lipid peroxidation and antioxidant defence systems. Comparison with non-selective and COX-2 selective NSAIDs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Catalase; Celecoxib; Colon; Cyclooxygenase 2 Inhibitors; Diclofenac; Gastric Mucosa; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glycine; Lipid Peroxidation; Liver; Male; Oxyphenonium; Pyrazoles; Pyrroles; Rats; Rats, Wistar; Sulfhydryl Compounds; Sulfonamides; Thiobarbituric Acid Reactive Substances; Tolmetin | 2007 |
Evaluation of intestinal absorption of amtolmetin guacyl in rats: breast cancer resistant protein as a primary barrier of oral bioavailability.
Topics: Adenosine; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Availability; Diketopiperazines; Glycine; Heterocyclic Compounds, 4 or More Rings; Intestinal Absorption; Intestinal Mucosa; Leukotriene Antagonists; Male; Mice; Mice, Knockout; Propionates; Pyrroles; Quinolines; Rats; Rats, Sprague-Dawley; Tolmetin; Vasodilator Agents; Verapamil | 2013 |