Page last updated: 2024-08-16

tolmetin and ketoprofen

tolmetin has been researched along with ketoprofen in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (27.03)	18.7374
1990's	9 (24.32)	18.2507
2000's	8 (21.62)	29.6817
2010's	9 (24.32)	24.3611
2020's	1 (2.70)	2.80

Authors

Authors	Studies
Bundgaard, H; Nielsen, NM	1
Apiwattanakul, N; Chairoungdua, A; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Sophasan, S	1
Topliss, JG; Yoshida, F	1
Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Gozalbes, R; Pineda-Lucena, A	1
Ekins, S; Williams, AJ; Xu, JJ	1
Bu, X; Cao, Y; Hu, X; Luo, M; Ren, Y; Song, Y; Wang, X; Xu, Q; Yuan, M	1
Cheng, YK; Hu, X; Li, Z; Liu, M; Luo, HB; Yuan, M	1
Kumar, M; Sinha, VR; Thareja, S	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Altman, RA; Borel, T; Davis, I; de Azambuja, F; Johnson, D; Liu, A; Sorrentino, JP; Udokwu, C; Yang, Y	1
Huskisson, EC	1
Miehlke, K	1
Pemberton, RE; Strand, LJ	1
Klein, G; Wottawa, A	2
Janssen, PA; Niemegeers, CJ; Van Bruggen, JA	1
Awouters, F; Janssen, PA; Lenaerts, PM; Niemegeers, CJ	1
Ward, JR	1
Court, H; Volans, GN	1
Accorra, F; Della Ventura, M; Dordoni, PL; Iannace, E; Paparella, P; Rocca, B; Stefanelli, A	1
Semrad, SD	1
Cabré, F; Carabaza, A; García, ML; Gómez, M; Gutiérrez, M; Mauleón, D; Rotllan, E	1
Borgå, B; Borgå, O	1
Niemi, TT; Rosenberg, PH; Taxell, C	1
Hendolin, H; Kokki, H; Kostamovaara, PA; Nuutinen, LS	1
Cabré, F; Díaz, I; Fernández-Guasti, A; López-Muñoz, FJ; Mauleón, D; Tost, D; Ventura, R	1
Saarnivaara, L; Tarkkila, P	1
Mardones, C; Ríos, A; Valcárcel, M	1
Aboul-Enein, HY; Kruk, I; Kładna, A; Lichszteld, K; Michalska, T	1
Lindon, JC; Nicholson, JK; Skordi, E; Wilson, ID	1
Cárdenas, S; Simonet, BM; Suárez, B; Valcárcel, M	1
Cárdenas, S; Cruz-Vera, M; Lucena, R; Valcárcel, M	1
Unlü, B; van Leeuwen, JS; Vermeulen, NP; Vos, JC	1
Allegretti, M; Aramini, A; Aschi, M; Bertini, R; Bizzarri, C; Cesta, MC; Crucianelli, M; Di Bitondo, R; Di Giacinto, C; Gloaguen, I; Moriconi, A; Sablone, MR	1

Reviews

3 review(s) available for tolmetin and ketoprofen

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Antiinflammatory drugs. Seminars in arthritis and rheumatism, 1977, Volume: 7, Issue:1 Topics: Adult; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Benzylidene Compounds; Child; Drug Evaluation; Female; Humans; Ibuprofen; Indenes; Indomethacin; Ketoprofen; Mefenamic Acid; Naproxen; Phenylacetates; Phenylbutazone; Pregnancy; Pregnancy Complications; Propionates; Tolmetin	1977
Update on ibuprofen for rheumatoid arthritis. The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Piroxicam; Sulindac; Thiazines; Tolmetin	1984

Trials

6 trial(s) available for tolmetin and ketoprofen

Article	Year
A review of upper-gastrointestinal effects of the newer nonsteroidal antiinflammatory agents. Digestive diseases and sciences, 1979, Volume: 24, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Evaluation; Fenoprofen; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Ibuprofen; Ketoprofen; Naproxen; Phenylbutazone; Registries; Sulindac; Tolmetin	1979
Update on ibuprofen for rheumatoid arthritis. The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Piroxicam; Sulindac; Thiazines; Tolmetin	1984
Effect of ketorolac, ketoprofen and nefopam on platelet function. Anaesthesia, 1994, Volume: 49, Issue:12 Topics: Bleeding Time; Blood Platelets; Cells, Cultured; Female; Humans; Ketoprofen; Ketorolac; Nefopam; Platelet Aggregation; Platelet Aggregation Inhibitors; Tolmetin	1994
Comparison of the effect of intravenous ketoprofen, ketorolac and diclofenac on platelet function in volunteers. Acta anaesthesiologica Scandinavica, 1997, Volume: 41, Issue:10 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Cross-Over Studies; Diclofenac; Double-Blind Method; Humans; Ketoprofen; Ketorolac; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Tolmetin	1997
Ketorolac, diclofenac and ketoprofen are equally efficacious for pain relief after total hip replacement surgery. British journal of anaesthesia, 1998, Volume: 81, Issue:3 Topics: Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Drug Administration Schedule; Female; Fentanyl; Humans; Ketoprofen; Ketorolac; Male; Middle Aged; Pain, Postoperative; Prospective Studies; Tolmetin	1998
Ketoprofen, diclofenac or ketorolac for pain after tonsillectomy in adults? British journal of anaesthesia, 1999, Volume: 82, Issue:1 Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Female; Humans; Ketoprofen; Ketorolac; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Tolmetin; Tonsillectomy	1999

Other Studies

29 other study(ies) available for tolmetin and ketoprofen

Article	Year
Esters of N,N-disubstituted 2-hydroxyacetamides as a novel highly biolabile prodrug type for carboxylic acid agents. Journal of medicinal chemistry, 1987, Volume: 30, Issue:3 Topics: Acetamides; Biotransformation; Carboxylic Acids; Half-Life; Humans; Indicators and Reagents; Kinetics; Structure-Activity Relationship	1987
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes. Molecular pharmacology, 1999, Volume: 55, Issue:5 Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carrier Proteins; Oocytes; Xenopus laevis	1999
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach. Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7 Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism	2005
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Identification of curcumin derivatives as human glyoxalase I inhibitors: A combination of biological evaluation, molecular docking, 3D-QSAR and molecular dynamics simulation studies. Bioorganic & medicinal chemistry, 2011, Feb-01, Volume: 19, Issue:3 Topics: Curcumin; Drug Design; Enzyme Inhibitors; Genetic Vectors; Humans; Inhibitory Concentration 50; Lactoylglutathione Lyase; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Molecular Targeted Therapy; Plasmids; Protein Binding; Protein Conformation; Quantitative Structure-Activity Relationship	2011
Structural investigation into the inhibitory mechanisms of indomethacin and its analogues towards human glyoxalase I. Bioorganic & medicinal chemistry letters, 2011, Jul-15, Volume: 21, Issue:14 Topics: Binding Sites; Catalytic Domain; Humans; Indomethacin; Kinetics; Lactoylglutathione Lyase; Molecular Dynamics Simulation; Thermodynamics	2011
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach. European journal of medicinal chemistry, 2012, Volume: 53 Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship	2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Diflunisal Derivatives as Modulators of ACMS Decarboxylase Targeting the Tryptophan-Kynurenine Pathway. Journal of medicinal chemistry, 2021, 01-14, Volume: 64, Issue:1 Topics: Bacterial Proteins; Binding Sites; Biosynthetic Pathways; Carboxy-Lyases; Catalytic Domain; Crystallography, X-Ray; Diflunisal; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kynurenine; Molecular Docking Simulation; NAD; Pseudomonas fluorescens; Structure-Activity Relationship; Tryptophan	2021
Old and new pharmaceutical non-steroidal compounds prescribed for the management of patients with rheumatic diseases. Rheumatology and rehabilitation, 1979, Volume: Suppl Topics: Anti-Inflammatory Agents; Fenoprofen; Humans; Ibuprofen; Ketoprofen; Naproxen; Rheumatic Diseases; Sulindac; Tolmetin	1979
[Effect of antirheumatic agents on DNA synthesis and DNA repair in various cell systems (proceedings)]. Zeitschrift fur Rheumatologie, 1976, Volume: 35 Suppl 4 Topics: Animals; Anti-Inflammatory Agents; Apazone; DNA; DNA Repair; Flufenamic Acid; Humans; Ketoprofen; Mice; Mutagens; Naproxen; Oxyphenbutazone; Phenothiazines; Rats; Tolmetin	1976
[Effect of antirheumatic agents on DNA-systems and DNA repair of various cell systems]. Verhandlungen der Deutschen Gesellschaft fur Rheumatologie, 1976, Volume: 4 Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; DNA; DNA Repair; Flufenamic Acid; Humans; In Vitro Techniques; Ketoprofen; Naproxen; Oxyphenbutazone; Phenothiazines; Tolmetin	1976
Suprofen, a potent antagonist of acetic acid-induced writhing in rats. Arzneimittel-Forschung, 1975, Volume: 25, Issue:10 Topics: Acetates; Analgesics; Animals; Arachidonic Acids; Aspirin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Indomethacin; Ketoprofen; Male; Muscle Contraction; Phenylacetates; Phenylbutazone; Phenylpropionates; Prostaglandin Antagonists; Prostaglandins; Rats; Spasm; Thiophenes; Tolmetin	1975
Suprofen, a potent antagonist of ultraviolet-erythema in guinea-pigs. Arzneimittel-Forschung, 1975, Volume: 25, Issue:10 Topics: Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Erythema; Guinea Pigs; Indomethacin; Ketoprofen; Male; Phenylbutazone; Phenylpropionates; Thiophenes; Time Factors; Tolmetin; Ultraviolet Rays	1975
Poisoning after overdose with non-steroidal anti-inflammatory drugs. Adverse drug reactions and acute poisoning reviews, 1984,Spring, Volume: 3, Issue:1 Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Child; Child, Preschool; Diflunisal; Female; Fenoprofen; Feprazone; Humans; Ibuprofen; Indomethacin; Ketoprofen; London; Male; Mefenamic Acid; Naproxen; Oxyphenbutazone; Phenylbutazone; Piroxicam; Thiazines; Tolmetin	1984
Comparative efficacy of flunixin, ketoprofen, and ketorolac for treating endotoxemic neonatal calves. American journal of veterinary research, 1993, Volume: 54, Issue:9 Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Blood Pressure; Cattle; Cattle Diseases; Clonixin; Eicosanoids; Endotoxins; Female; Ketoprofen; Ketorolac Tromethamine; Lactates; Lactic Acid; Lipopolysaccharides; Male; Tolmetin; Toxemia; Tromethamine	1993
Stereoselective inhibition of inducible cyclooxygenase by chiral nonsteroidal antiinflammatory drugs. Journal of clinical pharmacology, 1996, Volume: 36, Issue:6 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Flurbiprofen; Guinea Pigs; Humans; Isoenzymes; Ketoprofen; Ketorolac; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Sheep; Stereoisomerism; Tolmetin	1996
Serum protein binding of nonsteroidal antiinflammatory drugs: a comparative study. Journal of pharmacokinetics and biopharmaceutics, 1997, Volume: 25, Issue:1 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chromatography, High Pressure Liquid; Diclofenac; Female; Fenoprofen; Flurbiprofen; Humans; Ketoprofen; Male; Middle Aged; Naproxen; Protein Binding; Tolmetin	1997
Antinociceptive effects of S(+)-ketoprofen and other analgesic drugs in a rat model of pain induced by uric acid. Journal of clinical pharmacology, 1998, Volume: 38, Issue:S1 Topics: Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Biotransformation; Disease Models, Animal; Dose-Response Relationship, Drug; Flurbiprofen; Injections, Intraventricular; Ketoprofen; Ketorolac; Male; Morphine; Pain; Rats; Rats, Sprague-Dawley; Rats, Wistar; Stereoisomerism; Tolmetin; Tromethamine; Uric Acid	1998
Determination of nonsteroidal anti-inflammatory drugs in biological fluids by automatic on-line integration of solid-phase extraction and capillary electrophoresis. Electrophoresis, 2001, Volume: 22, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Automation; Chromatography, Micellar Electrokinetic Capillary; Humans; Ibuprofen; Indomethacin; Ketoprofen; Phenylbutyrates; Tolmetin	2001
Scavenging of reactive oxygen species by some nonsteroidal anti-inflammatory drugs and fenofibrate. Biopolymers, 2006, Jun-05, Volume: 82, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Electron Spin Resonance Spectroscopy; Fenofibrate; Fluorescence; Free Radical Scavengers; Hydroxyl Radical; Hypolipidemic Agents; Ketoprofen; Luminescent Measurements; Oxygen; Peroxides; Reactive Oxygen Species; Spin Labels; Spin Trapping; Superoxides; Tolmetin	2006
Kinetic studies on the intramolecular acyl migration of beta-1-O-acyl glucuronides: application to the glucuronides of (R)- and (S)-ketoprofen, (R)- and (S)-hydroxy-ketoprofen metabolites, and tolmetin by 1H-NMR spectroscopy. Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:7 Topics: Buffers; Glucuronic Acid; Ketoprofen; Kinetics; Magnetic Resonance Spectroscopy; Stereoisomerism; Tolmetin	2005
Determination of non-steroidal anti-inflammatory drugs in urine by combining an immobilized carboxylated carbon nanotubes minicolumn for solid-phase extraction with capillary electrophoresis-mass spectrometry. Journal of chromatography. A, 2007, Aug-03, Volume: 1159, Issue:1-2 Topics: Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Carboxylic Acids; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Indomethacin; Ketoprofen; Methanol; Nanotubes, Carbon; Sensitivity and Specificity; Solid Phase Extraction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tolmetin; Urine	2007
Ionic liquid-based dynamic liquid-phase microextraction: application to the determination of anti-inflammatory drugs in urine samples. Journal of chromatography. A, 2008, Aug-15, Volume: 1202, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Fractionation; Flurbiprofen; Humans; Hydrogen-Ion Concentration; Indomethacin; Ionic Liquids; Ketoprofen; Molecular Structure; Naproxen; Phenylbutyrates; Reproducibility of Results; Tolmetin	2008
Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs. Toxicology in vitro : an international journal published in association with BIBRA, 2012, Volume: 26, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; ATP-Binding Cassette Transporters; Biological Transport, Active; Cytochrome P-450 Enzyme System; Diclofenac; Electron Transport; Genes, MDR; Ibuprofen; Indomethacin; Ketoprofen; Ketorolac; Mitochondria; Naproxen; Reactive Oxygen Species; Sulindac; Tolmetin; Yeasts	2012
Structure-Activity Relationship of novel phenylacetic CXCR1 inhibitors. Bioorganic & medicinal chemistry letters, 2009, Aug-01, Volume: 19, Issue:15 Topics: Allosteric Regulation; Allosteric Site; Chemistry, Organic; Chemistry, Pharmaceutical; Chemotaxis; Humans; Inhibitory Concentration 50; Models, Chemical; Models, Molecular; Molecular Conformation; Mutagenesis; Mutation; Receptors, Interleukin-8A; Structure-Activity Relationship	2009