Page last updated: 2024-08-16

tolmetin and ibuprofen

tolmetin has been researched along with ibuprofen in 81 studies

Research

Studies (81)

Timeframe	Studies, this research(%)	All Research%
pre-1990	45 (55.56)	18.7374
1990's	20 (24.69)	18.2507
2000's	7 (8.64)	29.6817
2010's	7 (8.64)	24.3611
2020's	2 (2.47)	2.80

Authors

Authors	Studies
Ariyan, ZS; Fogt, SW; Heilman, RD; Matthews, RJ; Powers, LJ; Rippin, DJ	1
Apiwattanakul, N; Chairoungdua, A; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Sophasan, S	1
Topliss, JG; Yoshida, F	1
Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Kumar, M; Sinha, VR; Thareja, S	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Altman, RA; Borel, T; Davis, I; de Azambuja, F; Johnson, D; Liu, A; Sorrentino, JP; Udokwu, C; Yang, Y	1
Huskisson, EC	1
Gerrard, JM; Peterson, DA; Rao, GH; White, JG	1
Brewer, EJ	1
Hadler, NM; Kilpatrick, FW	1
Jabbs, JM; Maddi, VI; Pinals, RS; Runge, LA	1
Miehlke, K	1
Roe, RL	1
Cohen, GN; Fisherman, EW	1
Pemberton, RE; Strand, LJ	1
Lanza, FL; Nelson, RS; Royer, GL	1
Scherbel, AL	1
Kaye, RL; Pemberton, RE	1
Turner, R	1
Zarro, VJ	1
Healey, LA	1
Ehrlich, HP; Rockwell, WB	1
Beaver, WT; Forbes, JA; Grodin, CD; Kehm, CJ	1
Penning, TM; Smithgall, TE	1
Kunitake, LM; Pallasch, TJ	1
Cater, M; O'Brien, PM; Pickvance, NJ	1
Gasparich, JP; Mayo, ME	1
Hudyma, EO; Kollenberg, LO; Robbins, JM	1
Paulus, HE	1
Gross, JI; Vogel, RI	1
Bergman, SA; Crossley, HL; Wynn, RL	1
Caldwell, JR; Crain, D; Hoffmeister, RT; Kantrowitz, F; Lloyd, RJ; Nussdorf, RT; Repice, MR; Schmid, FR	1
Cooper, SA	2
Calin, A	1
Bender, WL; Beschorner, WE; Darwish, MO; Hall-Craggs, M; Solez, K; Whelton, A	1
Altman, RD	1
Ward, JR	1
Lanza, FL	1
Bhalla, AK; Simon, LS	1
Court, H; Volans, GN	1
Ciofalo, VB; Diamantis, W; Melton, J; Sofia, RD	1
De Castro, A; De Sarrazin, C; Laska, EM; Olson, NZ; Sunshine, A; Zighelboim, I	1
Zizic, TM	1
Mills, JA; Simon, LS	1
Haire, WD	1
Bird, HA; Leatham, PA; Rhind, VM; Wright, V	1
O'Brien, WM	1
Lindsley, CB	1
Chen, TT; Lanza, FL; Nelson, RS; Rack, MF; Royer, GL; Seckman, CE	1
Nash, DP	1
Barth, WF; Ruppert, GB	1
Paris, PM; Seaberg, DC; Turturro, MA	1
Blumenthal, PD; Furman, WR; Givogre, JL; Higgins, MS; Marco, AP	1
Morrison, NA; Repka, MX	1
Price, SD; Watson, WA; Wright, JM	1
Balevi, B	1
Dasgupta, A; Volk, A	1
Dasgupta, A; Timmerman, TG	1
Rømsing, J; Walther-Larsen, S	1
Frölich, JC; Stichtenoth, DO	1
Todd, KH	1
Gavin, TJ; Meeker, LD; Mixter, CG	1
Michael, LR; Southall, DM; Vasko, RM	1
Dendrinou-Samara, C; Ekateriniadou, LV; Kessissoglou, DP; Kortsaris, AH; Kyriakidis, DA; Raptopoulou, CP; Terzis, A; Tsotsou, G	1
Hall, SR; Loomis, C; Milne, B	1
Fowler, CJ; Janson, U; Johnson, RM; Norström, K; Stenström, A; Tiger, G; Wahlström, G	1
Browne, GS; Day, RO; Ellis, BA; Nelson, C; Nguyen, T; Williams, KM	1
Bell, A; Hosokawa, A; Jhamandas, K; Milne, B; Powell, KJ; Quirion, R; Sutak, M	1
Mardones, C; Ríos, A; Valcárcel, M	1
Barrio, DA; Cortizo, AM; Etcheverry, SB; Williams, PA	1
Burdan, F	1
Burdan, F; Dudka, J; Klepacz, R; Marzec, B; Szumilo, J	1
Atherton, J; Bauman, J; Kohl, C; Lam, W; Lou, Z; Mutlib, A; Reily, M; Walker, GS	1
Unlü, B; van Leeuwen, JS; Vermeulen, NP; Vos, JC	1
Chai, MZ; Flanagan, JU; Squire, CJ; Teague, RM; Turnbull, AP; Yosaatmadja, Y	1
Abdelbaser, I; ALseoudy, MM; El-Emam, EM; Mageed, NA	1

Reviews

11 review(s) available for tolmetin and ibuprofen

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Antiinflammatory drugs. Seminars in arthritis and rheumatism, 1977, Volume: 7, Issue:1 Topics: Adult; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Benzylidene Compounds; Child; Drug Evaluation; Female; Humans; Ibuprofen; Indenes; Indomethacin; Ketoprofen; Mefenamic Acid; Naproxen; Phenylacetates; Phenylbutazone; Pregnancy; Pregnancy Complications; Propionates; Tolmetin	1977
Drug therapy in rheumatic diseases. The Medical clinics of North America, 1977, Volume: 61, Issue:2 Topics: Acetaminophen; Adrenal Cortex Hormones; Antimalarials; Aspirin; Colchicine; Fenoprofen; Gold; Humans; Ibuprofen; Indomethacin; Levamisole; Naproxen; Penicillamine; Phenylbutazone; Rheumatic Diseases; Tolmetin	1977
Treatment of rheumatoid arthritis: a review including newer and experimental anti-inflammatory agents. Archives of internal medicine, 1976, Volume: 136, Issue:9 Topics: Activities of Daily Living; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin; Aurothioglucose; Fenoprofen; Humans; Ibuprofen; Immunosuppressive Agents; Indomethacin; Naproxen; Oxyphenbutazone; Penicillamine; Phenylbutazone; Physical Therapy Modalities; Tolmetin	1976
Nonsteroidal anti-inflammatory agents in relieving dental pain: a review. Journal of the American Dental Association (1939), 1983, Volume: 106, Issue:1 Topics: Analgesics; Anti-Inflammatory Agents; Chemical Phenomena; Chemistry; Drug Interactions; Humans; Ibuprofen; Kinetics; Mouth; Pain, Postoperative; Tolmetin	1983
New peripherally-acting oral analgesic agents. Annual review of pharmacology and toxicology, 1983, Volume: 23 Topics: Administration, Oral; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Diflunisal; Humans; Ibuprofen; Indoprofen; Naproxen; Pain; Pain, Postoperative; Tolmetin	1983
Clinical use of tolmetin sodium in patients with ankylosing spondylitis: a review. Journal of clinical pharmacology, 1983, Volume: 23, Issue:7 Topics: Clinical Trials as Topic; Double-Blind Method; Humans; Ibuprofen; Indomethacin; Pyrroles; Spondylitis, Ankylosing; Tolmetin	1983
Review of ibuprofen for osteoarthritis. The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Meclofenamic Acid; Naproxen; Osteoarthritis; Phenylbutazone; Sulindac; Tolmetin	1984
Update on ibuprofen for rheumatoid arthritis. The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Piroxicam; Sulindac; Thiazines; Tolmetin	1984
Nonsteroidal antiinflammatory drugs (second of two parts). The New England journal of medicine, 1980, May-29, Volume: 302, Issue:22 Topics: Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Fenoprofen; Humans; Ibuprofen; Mefenamic Acid; Naproxen; Propionates; Sulindac; Tolmetin	1980
Peri-operative use of nonsteroidal anti-inflammatory drugs in children: analgesic efficacy and bleeding. Anaesthesia, 1997, Volume: 52, Issue:7 Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Diclofenac; Drug Administration Schedule; Humans; Ibuprofen; Infant; Ketorolac; Pain, Postoperative; Postoperative Hemorrhage; Randomized Controlled Trials as Topic; Tolmetin	1997

Trials

18 trial(s) available for tolmetin and ibuprofen

Article	Year
Hypersensitivity to five non-steroidal anti-inflammatory agents: ibuprofen, fenoprofen, indomethacin, naproxen and tolmetin. Annals of allergy, 1978, Volume: 41, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Drug Hypersensitivity; Fenoprofen; Humans; Ibuprofen; Indomethacin; Iodides; Naproxen; Tolmetin	1978
A review of upper-gastrointestinal effects of the newer nonsteroidal antiinflammatory agents. Digestive diseases and sciences, 1979, Volume: 24, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Evaluation; Fenoprofen; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Ibuprofen; Ketoprofen; Naproxen; Phenylbutazone; Registries; Sulindac; Tolmetin	1979
Effects of ibuprofen, tolmetin and placebo on the gastric mucosa of aspirin-sensitive volunteers. The American journal of gastroenterology, 1979, Volume: 72, Issue:5 Topics: Adult; Aspirin; Gastric Mucosa; Gastritis; Gastroscopy; Humans; Ibuprofen; Placebos; Pyrroles; Tolmetin	1979
Evaluation of ketorolac, ibuprofen, acetaminophen, and an acetaminophen-codeine combination in postoperative oral surgery pain. Pharmacotherapy, 1990, Volume: 10, Issue:6 ( Pt 2) Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Codeine; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Humans; Ibuprofen; Ketorolac Tromethamine; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Tolmetin; Tooth, Impacted; Tromethamine	1990
A double-blind comparison of the new ibuprofen-codeine phosphate combination, zomepirac, and placebo in the relief of postepisiotomy pain. Clinical therapeutics, 1985, Volume: 7, Issue:4 Topics: Adult; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Combinations; Episiotomy; Female; Humans; Ibuprofen; Pain, Postoperative; Pyrroles; Random Allocation; Time Factors; Tolmetin	1985
Four-way, multicenter, crossover trial of ibuprofen, fenoprofen calcium, naproxen, and tolmetin sodium in osteoarthritis: comparative clinical profiles. Southern medical journal, 1983, Volume: 76, Issue:6 Topics: Adult; Aged; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Tolerance; Female; Fenoprofen; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis; Phenylpropionates; Pyrroles; Tolmetin	1983
New peripherally-acting oral analgesic agents. Annual review of pharmacology and toxicology, 1983, Volume: 23 Topics: Administration, Oral; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Diflunisal; Humans; Ibuprofen; Indoprofen; Naproxen; Pain; Pain, Postoperative; Tolmetin	1983
Clinical use of tolmetin sodium in patients with ankylosing spondylitis: a review. Journal of clinical pharmacology, 1983, Volume: 23, Issue:7 Topics: Clinical Trials as Topic; Double-Blind Method; Humans; Ibuprofen; Indomethacin; Pyrroles; Spondylitis, Ankylosing; Tolmetin	1983
Review of ibuprofen for osteoarthritis. The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Meclofenamic Acid; Naproxen; Osteoarthritis; Phenylbutazone; Sulindac; Tolmetin	1984
Update on ibuprofen for rheumatoid arthritis. The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Piroxicam; Sulindac; Thiazines; Tolmetin	1984
Endoscopic studies of gastric and duodenal injury after the use of ibuprofen, aspirin, and other nonsteroidal anti-inflammatory agents. The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A Topics: Adolescent; Adult; Anti-Inflammatory Agents; Aspirin; Buffers; Duodenum; Endoscopy; Female; Gastric Mucosa; Humans; Ibuprofen; Indomethacin; Intestinal Mucosa; Male; Middle Aged; Naproxen; Time Factors; Tolmetin	1984
Ibuprofen, zomepirac, aspirin, and placebo in the relief of postepisiotomy pain. Clinical pharmacology and therapeutics, 1983, Volume: 34, Issue:2 Topics: Adolescent; Adult; Aspirin; Episiotomy; Female; Humans; Ibuprofen; Pain, Postoperative; Placebos; Pyrroles; Tolmetin	1983
A comparative endoscopic evaluation of the damaging effects of nonsteroidal anti-inflammatory agents on the gastric and duodenal mucosa. The American journal of gastroenterology, 1981, Volume: 75, Issue:1 Topics: Adult; Anti-Inflammatory Agents; Duodenum; Endoscopy; Gastric Mucosa; Humans; Ibuprofen; Indomethacin; Intestinal Mucosa; Middle Aged; Naproxen; Tolmetin	1981
Intramuscular ketorolac versus oral ibuprofen in acute musculoskeletal pain. Annals of emergency medicine, 1995, Volume: 26, Issue:2 Topics: Administration, Oral; Adolescent; Adult; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Humans; Ibuprofen; Injections, Intravenous; Ionophores; Ketorolac; Middle Aged; Musculoskeletal Diseases; Pain; Prospective Studies; Tolmetin; Wounds and Injuries	1995
Recovery from outpatient laparoscopic tubal ligation is not improved by preoperative administration of ketorolac or ibuprofen. Anesthesia and analgesia, 1994, Volume: 79, Issue:2 Topics: Adult; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Ketorolac; Laparoscopy; Pain, Postoperative; Premedication; Prospective Studies; Sterilization, Tubal; Time Factors; Tolmetin; Treatment Outcome	1994
Ketorolac versus acetaminophen or ibuprofen in controlling postoperative pain in patients with strabismus. Ophthalmology, 1994, Volume: 101, Issue:5 Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Ibuprofen; Injections, Intravenous; Ketorolac; Male; Middle Aged; Pain, Postoperative; Prospective Studies; Strabismus; Tolmetin	1994
Preemptive pain control in patients having laparoscopic hernia repair: a comparison of ketorolac and ibuprofen. Archives of surgery (Chicago, Ill. : 1960), 1998, Volume: 133, Issue:4 Topics: Administration, Oral; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Hernia, Inguinal; Humans; Ibuprofen; Injections, Intravenous; Intraoperative Care; Ketorolac Tromethamine; Laparoscopy; Middle Aged; Pain Measurement; Pain, Postoperative; Preoperative Care; Prospective Studies; Tolmetin; Tromethamine	1998
Comparison of intravenous ibuprofen versus ketorolac for postoperative analgesia in children undergoing lower abdominal surgery: A randomized, controlled, non-inferiority study. Revista espanola de anestesiologia y reanimacion, 2022, Volume: 69, Issue:8 Topics: Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Child; Double-Blind Method; Humans; Ibuprofen; Ketorolac; Morphine; Pain, Postoperative; Tolmetin	2022

Other Studies

56 other study(ies) available for tolmetin and ibuprofen

Article	Year
Effect of structural change on acute toxicity and antiinflammatory activity in a series of imidazothiazoles and thiazolobenzimidazoles. Journal of medicinal chemistry, 1981, Volume: 24, Issue:5 Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Chemical Phenomena; Chemistry; Imidazoles; Lethal Dose 50; Locomotion; Male; Mice; Muscle Tonus; Nervous System; Orientation; Rats; Structure-Activity Relationship; Thiazoles	1981
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes. Molecular pharmacology, 1999, Volume: 55, Issue:5 Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carrier Proteins; Oocytes; Xenopus laevis	1999
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach. Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7 Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism	2005
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach. European journal of medicinal chemistry, 2012, Volume: 53 Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship	2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Diflunisal Derivatives as Modulators of ACMS Decarboxylase Targeting the Tryptophan-Kynurenine Pathway. Journal of medicinal chemistry, 2021, 01-14, Volume: 64, Issue:1 Topics: Bacterial Proteins; Binding Sites; Biosynthetic Pathways; Carboxy-Lyases; Catalytic Domain; Crystallography, X-Ray; Diflunisal; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kynurenine; Molecular Docking Simulation; NAD; Pseudomonas fluorescens; Structure-Activity Relationship; Tryptophan	2021
Inhibition of ferrous iron induced oxidation of arachidonic acid by indomethacin. Prostaglandins and medicine, 1979, Volume: 2, Issue:2 Topics: Arachidonic Acids; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ferrous Compounds; Ibuprofen; Indomethacin; Iron; Models, Chemical; Nitroblue Tetrazolium; Oxidation-Reduction; Tolmetin	1979
Nonsteroidal antiinflammatory agents. Arthritis and rheumatism, 1977, Volume: 20, Issue:2 Suppl Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Child, Preschool; Humans; Ibuprofen; Indomethacin; Infant; Phenylbutazone; Tolmetin	1977
New non-steroidal anti-inflammatory drugs. North Carolina medical journal, 1977, Volume: 38, Issue:3 Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Fenoprofen; Humans; Ibuprofen; Naproxen; Penicillamine; Tolmetin	1977
New nonsteroidal anti-inflammatory drugs. Prospective survey of relative merits. New York state journal of medicine, 1977, Volume: 77, Issue:8 Topics: Anti-Inflammatory Agents; Fenoprofen; Humans; Ibuprofen; Naproxen; Rheumatic Diseases; Tolmetin	1977
Old and new pharmaceutical non-steroidal compounds prescribed for the management of patients with rheumatic diseases. Rheumatology and rehabilitation, 1979, Volume: Suppl Topics: Anti-Inflammatory Agents; Fenoprofen; Humans; Ibuprofen; Ketoprofen; Naproxen; Rheumatic Diseases; Sulindac; Tolmetin	1979
Nonsteroidal antiinflammatory drugs: new alternatives for rheumatic disease. Postgraduate medicine, 1978, Volume: 63, Issue:3 Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Drug Therapy, Combination; Fenoprofen; Humans; Ibuprofen; Naproxen; Phenylpropionates; Pyrroles; Tolmetin	1978
Aspirin and newer anti-inflammatory agents in rheumatoid arthritis. American family physician, 1977, Volume: 16, Issue:1 Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Fenoprofen; Humans; Ibuprofen; Indomethacin; Naproxen; Peptic Ulcer; Phenylbutazone; Tolmetin	1977
New nonsteroidal anti-inflammatory drugs. American family physician, 1976, Volume: 14, Issue:3 Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Fenoprofen; Humans; Ibuprofen; Naphthaleneacetic Acids; Naproxen; Phenylpropionates; Pyrroles; Tolmetin	1976
More on the new arthritis drugs. Medical times, 1976, Volume: 104, Issue:12 Topics: Arthritis; Fenoprofen; Humans; Ibuprofen; Naproxen; Tolmetin	1976
An ibuprofen-antagonized plasmin inhibitor released by human endothelial cells. Experimental and molecular pathology, 1991, Volume: 54, Issue:1 Topics: Antifibrinolytic Agents; Burns; Cells, Cultured; Cicatrix; Endothelium; Fibrinolysis; Hot Temperature; Humans; Ibuprofen; In Vitro Techniques; Indomethacin; Skin; Thrombosis; Tolmetin	1991
Inhibition of trans-dihydrodiol oxidation by the non-steroidal anti-inflammatory drugs. Carcinogenesis, 1986, Volume: 7, Issue:4 Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Anti-Inflammatory Agents; Aspirin; Benzopyrenes; Dihydroxydihydrobenzopyrenes; Flufenamic Acid; Ibuprofen; Indomethacin; Liver; Male; Meclofenamic Acid; Mefenamic Acid; Oxidoreductases; Rats; Sulindac; Tolmetin	1986
Nonsteroidal anti-inflammatory analgesics. The Compendium of continuing education in dentistry, 1985, Volume: 6, Issue:1 Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diflunisal; Drug Interactions; Humans; Ibuprofen; Tolmetin	1985
Comparative effects of four prostaglandin synthesis inhibitors on the obstructed kidney in the dog. The Journal of urology, 1986, Volume: 135, Issue:5 Topics: Animals; Blood Pressure; Dogs; Female; Ibuprofen; Indomethacin; Ketorolac; Kidney Pelvis; Naproxen; Pressure; Prostaglandin Antagonists; Tolmetin; Ureteral Obstruction	1986
Nonsteroidal anti-inflammatory agents. A review of the literature. Journal of the American Podiatric Medical Association, 1985, Volume: 75, Issue:10 Topics: Absorption; Anti-Inflammatory Agents; Aspirin; Diflunisal; Drug Interactions; Female; Fenoprofen; Half-Life; Humans; Ibuprofen; Indomethacin; Kinetics; Meclofenamic Acid; Naproxen; Phenylbutazone; Piroxicam; Pregnancy; Thiazines; Tolmetin	1985
Government affairs. FDA Arthritis Advisory Committee Meeting. Arthritis and rheumatism, 1983, Volume: 26, Issue:11 Topics: Anaphylaxis; Drug Evaluation; Humans; Ibuprofen; Palliative Care; Pyrroles; Rheumatic Diseases; Tolmetin	1983
The effects of nonsteroidal anti-inflammatory analgesics on pain after periodontal surgery. Journal of the American Dental Association (1939), 1984, Volume: 109, Issue:5 Topics: Adolescent; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Humans; Ibuprofen; Middle Aged; Pain, Postoperative; Periodontal Diseases; Placebos; Prospective Studies; Pyrroles; Tolmetin	1984
Interstitial nephritis, proteinuria, and renal failure caused by nonsteroidal anti-inflammatory drugs. Immunologic characterization of the inflammatory infiltrate. The American journal of medicine, 1984, Volume: 76, Issue:6 Topics: Adult; Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal; Biopsy; Female; Fenoprofen; Fluorescent Antibody Technique; Humans; Ibuprofen; Kidney Diseases; Kidney Glomerulus; Male; Middle Aged; Nephritis, Interstitial; Phenylpropionates; Proteinuria; T-Lymphocytes, Cytotoxic; Tolmetin	1984
Five studies on ibuprofen for postsurgical dental pain. The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A Topics: Acetaminophen; Adolescent; Adult; Analgesics; Aspirin; Codeine; Drug Combinations; Female; Humans; Ibuprofen; Male; Pain, Postoperative; Periodontal Diseases; Surgery, Oral; Tolmetin; Tooth, Impacted	1984
A clinical evaluation of the antiarthritic agents. Comprehensive therapy, 1984, Volume: 10, Issue:8 Topics: Anti-Inflammatory Agents; Antimalarials; Arthritis; Aspirin; Diflunisal; Fenoprofen; Glucocorticoids; Gold; Humans; Ibuprofen; Immunosuppressive Agents; Indomethacin; Naproxen; ortho-Aminobenzoates; Penicillamine; Piroxicam; Prostaglandin Antagonists; Salicylates; Sulindac; Thiazines; Tolmetin	1984
Poisoning after overdose with non-steroidal anti-inflammatory drugs. Adverse drug reactions and acute poisoning reviews, 1984,Spring, Volume: 3, Issue:1 Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Child; Child, Preschool; Diflunisal; Female; Fenoprofen; Feprazone; Humans; Ibuprofen; Indomethacin; Ketoprofen; London; Male; Mefenamic Acid; Naproxen; Oxyphenbutazone; Phenylbutazone; Piroxicam; Thiazines; Tolmetin	1984
Comparative gastric ulcerogenic effects of meseclazone, 5-chlorosalicylic acid and other nonsteroidal anti-inflammatory drugs following acute and repeated oral administration to rats. Toxicology and applied pharmacology, 1980, Mar-15, Volume: 52, Issue:3 Topics: Animals; Anti-Inflammatory Agents; Benzoxazines; Biotransformation; Fenoprofen; Ibuprofen; Indomethacin; Male; Naproxen; Oxazines; Peptic Ulcer Hemorrhage; Phenylbutazone; Rats; Salicylates; Stomach Ulcer; Time Factors; Tolmetin	1980
Rheumatoid arthritis IV: non-steroidal anti-inflammatory agents use in treatment. Maryland state medical journal, 1982, Volume: 31, Issue:7 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Fenoprofen; Humans; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone; Tolmetin	1982
Hemophilic osteoarthropathy. Archives of internal medicine, 1982, Volume: 142, Issue:5 Topics: Analgesics; Bone Diseases; Hemophilia A; Humans; Ibuprofen; Joint Diseases; Tolmetin	1982
Non-steroidals ineffective in OA. Rheumatology and rehabilitation, 1982, Volume: 21, Issue:3 Topics: Humans; Ibuprofen; Osteoarthritis; Placebos; Pyrroles; Tolmetin	1982
Nonsteroidal anti-inflammatory drugs. Pharmacology, 1982, Volume: 25 Suppl 1 Topics: Adrenal Cortex Hormones; Analgesics; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Gold; Humans; Ibuprofen; Tolmetin	1982
Pharmacotherapy of juvenile rheumatoid arthritis. Pediatric clinics of North America, 1981, Volume: 28, Issue:1 Topics: Adrenal Cortex Hormones; Antimalarials; Arthritis, Juvenile; Chemical and Drug Induced Liver Injury; Child; Delayed-Action Preparations; Gold; Humans; Ibuprofen; Indomethacin; Penicillamine; Salicylates; Sulindac; Tolmetin	1981
Current review and comparison of the new nonsteroidal anti-inflammatory agents. The Journal of foot surgery, 1980,Winter, Volume: 19, Issue:4 Topics: Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Drug Administration Schedule; Fenoprofen; Humans; Ibuprofen; Naproxen; Prostaglandins; Sulindac; Tolmetin	1980
Tolmetin-induced aseptic meningitis. JAMA, 1981, Jan-02, Volume: 245, Issue:1 Topics: Adult; Female; Fever; Humans; Ibuprofen; Knee; Lupus Erythematosus, Systemic; Meningitis; Meningitis, Aseptic; Pain; Pyrroles; Tolmetin	1981
NSAID use and efficacy in the emergency department: single doses of oral ibuprofen versus intramuscular ketorolac. The Annals of pharmacotherapy, 1994, Volume: 28, Issue:3 Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Emergency Service, Hospital; Female; Hospitals, Teaching; Hospitals, Urban; Humans; Ibuprofen; Injections, Intramuscular; Ketorolac; Male; Pain; Pain Measurement; Retrospective Studies; Tolmetin	1994
Ketorolac versus ibuprofen: a simple cost-efficacy comparison for dental use. Journal (Canadian Dental Association), 1994, Volume: 60, Issue:1 Topics: Analgesics; Cost-Benefit Analysis; Humans; Ibuprofen; Ketorolac; Pain, Postoperative; Tolmetin; Tooth Extraction; Toothache	1994
Displacement of valproic acid and carbamazepine from protein binding in normal and uremic sera by tolmetin, ibuprofen, and naproxen: presence of inhibitor in uremic serum that blocks valproic acid-naproxen interactions. Therapeutic drug monitoring, 1996, Volume: 18, Issue:3 Topics: Binding, Competitive; Blood Proteins; Carbamazepine; Cyclooxygenase Inhibitors; Drug Interactions; Humans; Ibuprofen; Naproxen; Protein Binding; Reference Values; Tolmetin; Uremia; Valproic Acid	1996
In vitro displacement of phenytoin from protein binding by nonsteroidal antiinflammatory drugs tolmetin, ibuprofen, and naproxen in normal and uremic sera. Therapeutic drug monitoring, 1996, Volume: 18, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Humans; Ibuprofen; Naproxen; Phenytoin; Protein Binding; Serum Albumin; Tolmetin; Uremia	1996
Anesthesiology. The New England journal of medicine, 1998, Mar-05, Volume: 338, Issue:10 Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Ketorolac; Pain, Postoperative; Piroxicam; Tolmetin	1998
If you have no destination, any road will do. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 1998, Volume: 5, Issue:2 Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Ketorolac; Musculoskeletal System; Pain; Research Design; Tolmetin	1998
Intrathecal NSAIDS attenuate inflammation-induced neuropeptide release from rat spinal cord slices. Pain, 1998, Volume: 78, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Cyclooxygenase Inhibitors; Freund's Adjuvant; Hyperalgesia; Ibuprofen; In Vitro Techniques; Injections, Spinal; Ketorolac; Male; Myelitis; Neuropeptides; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tolmetin	1998
Anti-inflammatory drugs interacting with Zn(II), Cd(II) and Pt(II) metal ions. Journal of inorganic biochemistry, 1998, Volume: 71, Issue:3-4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacteria; Cadmium; Cations, Divalent; Cell Division; Cell Line; Chelating Agents; Cricetinae; Crystallography, X-Ray; Drug Interactions; Humans; Ibuprofen; In Vitro Techniques; Indomethacin; Ligands; Models, Molecular; Platinum; Structure-Activity Relationship; Tolmetin; Tumor Cells, Cultured; Zinc	1998
Spinal action of ketorolac, S(+)- and R(-)-ibuprofen on non-noxious activation of the catechol oxidation in the rat locus coeruleus: evidence for a central role of prostaglandins in the strychnine model of allodynia. Anesthesiology, 1999, Volume: 90, Issue:1 Topics: Anesthesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Catechols; Electrophysiology; Glycine Agents; Ibuprofen; Injections, Spinal; Ketorolac; Locus Coeruleus; Oxidation-Reduction; Pain; Physical Stimulation; Rats; Spinal Cord; Strychnine; Tolmetin	1999
Inhibition of anandamide hydrolysis by the enantiomers of ibuprofen, ketorolac, and flurbiprofen. Archives of biochemistry and biophysics, 1999, Feb-15, Volume: 362, Issue:2 Topics: Aging; Animals; Arachidonic Acids; Brain; Cell Extracts; Cell Survival; Dose-Response Relationship, Drug; Endocannabinoids; Flurbiprofen; Glioma; Hydrolysis; Ibuprofen; Inhibitory Concentration 50; Ketorolac; Kinetics; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Stereoisomerism; Time Factors; Tolmetin; Tumor Cells, Cultured	1999
Stereoselective and substrate-dependent inhibition of hepatic mitochondria beta-oxidation and oxidative phosphorylation by the non-steroidal anti-inflammatory drugs ibuprofen, flurbiprofen, and ketorolac. Biochemical pharmacology, 1999, Apr-01, Volume: 57, Issue:7 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Coenzyme A; Flurbiprofen; Ibuprofen; Ketorolac; Lipid Metabolism; Male; Mitochondria, Liver; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Palmitic Acid; Rats; Rats, Wistar; Stereoisomerism; Tolmetin	1999
Comparative effects of cyclo-oxygenase and nitric oxide synthase inhibition on the development and reversal of spinal opioid tolerance. British journal of pharmacology, 1999, Volume: 127, Issue:3 Topics: Analgesics, Opioid; Animals; Cyclooxygenase Inhibitors; Drug Tolerance; Enzyme Inhibitors; Ibuprofen; Injections, Intraperitoneal; Injections, Spinal; Ketorolac; Male; Morphine; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nociceptors; Rats; Rats, Sprague-Dawley; Spinal Cord; Tolmetin	1999
Determination of nonsteroidal anti-inflammatory drugs in biological fluids by automatic on-line integration of solid-phase extraction and capillary electrophoresis. Electrophoresis, 2001, Volume: 22, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Automation; Chromatography, Micellar Electrokinetic Capillary; Humans; Ibuprofen; Indomethacin; Ketoprofen; Phenylbutyrates; Tolmetin	2001
Three new vanadyl(IV) complexes with non-steroidal anti-inflammatory drugs (Ibuprofen, Naproxen and Tolmetin). Bioactivity on osteoblast-like cells in culture. Journal of inorganic biochemistry, 2002, Jan-01, Volume: 88, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Dose-Response Relationship, Drug; Ibuprofen; Mice; Naproxen; Organometallic Compounds; Osteoblasts; Rats; Spectrum Analysis; Tolmetin; Tumor Cells, Cultured; Vanadates	2002
Developmental toxicity evaluation of ibuprofen and tolmetin administered in triple daily doses to Wistar CRL:(WI)WUBR rats. Birth defects research. Part B, Developmental and reproductive toxicology, 2004, Volume: 71, Issue:5 Topics: Animals; Aspirin; Body Weight; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Fetal Development; Fetal Growth Retardation; Fetus; Heart Septal Defects, Ventricular; Ibuprofen; Maternal Exposure; Pregnancy; Rats; Rats, Wistar; Tolmetin	2004
Skeletal developmental effects of selective and nonselective cyclooxygenase-2 inhibitors administered through organogenesis and fetogenesis in Wistar CRL:(WI)WUBR rats. Toxicology, 2005, Dec-15, Volume: 216, Issue:2-3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Development; Cathepsin K; Cathepsins; Chondrocytes; Collagen; Cyclooxygenase 2 Inhibitors; Drug Evaluation, Preclinical; Epiphyses; Female; Femur; Fetal Development; Ibuprofen; Immunohistochemistry; Male; Organogenesis; Osteocalcin; Osteogenesis; Osteopontin; Pregnancy; Rats; Rats, Wistar; Sialoglycoproteins; Tolmetin; Tumor Necrosis Factor-alpha	2005
Determination of degradation pathways and kinetics of acyl glucuronides by NMR spectroscopy. Chemical research in toxicology, 2007, Volume: 20, Issue:6 Topics: Acylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile; Chromatography, Liquid; Cyclooxygenase Inhibitors; Diclofenac; Drug Stability; Flufenamic Acid; Glucuronides; Half-Life; Ibuprofen; Indomethacin; Kinetics; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mefenamic Acid; Molecular Structure; Rats; Rats, Sprague-Dawley; Stereoisomerism; Technology, Pharmaceutical; Tolmetin	2007
Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs. Toxicology in vitro : an international journal published in association with BIBRA, 2012, Volume: 26, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; ATP-Binding Cassette Transporters; Biological Transport, Active; Cytochrome P-450 Enzyme System; Diclofenac; Electron Transport; Genes, MDR; Ibuprofen; Indomethacin; Ketoprofen; Ketorolac; Mitochondria; Naproxen; Reactive Oxygen Species; Sulindac; Tolmetin; Yeasts	2012
Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3. PloS one, 2012, Volume: 7, Issue:8 Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Anti-Inflammatory Agents, Non-Steroidal; Flufenamic Acid; Flurbiprofen; Hydroxyprostaglandin Dehydrogenases; Ibuprofen; Indomethacin; Meclofenamic Acid; Mefenamic Acid; Naproxen; Sulindac; Tolmetin	2012