Page last updated: 2024-08-16

tolmetin and flurbiprofen

tolmetin has been researched along with flurbiprofen in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19903 (12.00)18.7374
1990's12 (48.00)18.2507
2000's3 (12.00)29.6817
2010's7 (28.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Keeley, SL; Maryanoff, BE; Persico, FJ1
Apiwattanakul, N; Chairoungdua, A; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Sophasan, S1
Topliss, JG; Yoshida, F1
Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Gozalbes, R; Pineda-Lucena, A1
Ekins, S; Williams, AJ; Xu, JJ1
Kumar, M; Sinha, VR; Thareja, S1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cooper, SA; Kupperman, A1
Laska, EM; Marrero, I; McCormick, N; Olson, N; Sunshine, A1
ElAttar, TM; Lin, HS; Tira, DE1
Buchanan, W; Doyle, MJ; Goodale, MB; Haigh, S; Jeffcoat, MK; Meredith, MP; Nelson, SL; Reddy, MS; Wehmeyer, KR1
Ward, DA1
Cabré, F; Carabaza, A; García, ML; Gómez, M; Gutiérrez, M; Mauleón, D; Rotllan, E1
Apple, DJ; Solomon, KD; Stewart, JA; Turkalj, JW; Whiteside, SB1
Dhaliwal, U; Gupta, VP; Prasad, N1
Borgå, B; Borgå, O1
Cabré, F; Díaz, I; Fernández-Guasti, A; López-Muñoz, FJ; Mauleón, D; Tost, D; Ventura, R1
Fowler, CJ; Janson, U; Johnson, RM; Norström, K; Stenström, A; Tiger, G; Wahlström, G1
Browne, GS; Day, RO; Ellis, BA; Nelson, C; Nguyen, T; Williams, KM1
Borodkin, MJ; McDonald, MB; Ocmand, A; Shoelson, B; Thompson, H; Wyse, TB1
Cárdenas, S; Cruz-Vera, M; Lucena, R; Valcárcel, M1
Chai, MZ; Flanagan, JU; Squire, CJ; Teague, RM; Turnbull, AP; Yosaatmadja, Y1

Reviews

1 review(s) available for tolmetin and flurbiprofen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

6 trial(s) available for tolmetin and flurbiprofen

ArticleYear
The analgesic efficacy of flurbiprofen compared to acetaminophen with codeine.
    The Journal of clinical dentistry, 1991, Volume: 2, Issue:3

    Topics: Acetaminophen; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distribution; Codeine; Double-Blind Method; Drug Combinations; Female; Flurbiprofen; Humans; Male; Pain Measurement; Pain, Postoperative; Tolmetin

1991
Comparative study of flurbiprofen, zomepirac sodium, acetaminophen plus codeine, and acetaminophen for the relief of postsurgical dental pain.
    The American journal of medicine, 1986, Mar-24, Volume: 80, Issue:3A

    Topics: Acetaminophen; Adult; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Flurbiprofen; Humans; Male; Pain, Postoperative; Placebos; Propionates; Pyrroles; Tolmetin; Tooth Extraction

1986
A comparison of topical ketorolac, systemic flurbiprofen, and placebo for the inhibition of bone loss in adult periodontitis.
    Journal of periodontology, 1995, Volume: 66, Issue:5

    Topics: Adult; Alveolar Bone Loss; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Dental Plaque Index; Dinoprostone; Double-Blind Method; Female; Flurbiprofen; Gingival Crevicular Fluid; Humans; Interleukin-1; Ketorolac Tromethamine; Male; Middle Aged; Mouthwashes; Periodontal Index; Periodontitis; Radiography; Statistics, Nonparametric; Subtraction Technique; Tolmetin; Treatment Outcome; Tromethamine

1995
Topical 0.5% ketorolac vs 0.03% flurbiprofen for inhibition of miosis during cataract surgery.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1997, Volume: 115, Issue:9

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Female; Flurbiprofen; Humans; Ketorolac Tromethamine; Lenses, Intraocular; Male; Middle Aged; Miosis; Ophthalmic Solutions; Phacoemulsification; Prospective Studies; Pupil; Tolmetin; Treatment Outcome; Tromethamine

1997
Ketorolac tromethamine in the maintenance of intraoperative mydriasis.
    Ophthalmic surgery and lasers, 1997, Volume: 28, Issue:9

    Topics: Administration, Oral; Administration, Topical; Adult; Aged; Aged, 80 and over; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Double-Blind Method; Drug Administration Routes; Drug Therapy, Combination; Female; Flurbiprofen; Humans; Ketorolac Tromethamine; Lenses, Intraocular; Male; Middle Aged; Prospective Studies; Pupil; Tolmetin; Tromethamine

1997
Comparison of the effectiveness of 4 anti-inflammatory drops in relieving photophobia after pupil dilation.
    Journal of cataract and refractive surgery, 1999, Volume: 25, Issue:3

    Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Flurbiprofen; Follow-Up Studies; Humans; Ketorolac; Light; Mydriatics; Ophthalmic Solutions; Prednisolone; Prospective Studies; Pupil; Tolmetin; Treatment Outcome; Vision Disorders

1999

Other Studies

18 other study(ies) available for tolmetin and flurbiprofen

ArticleYear
Replacement of aromatic or heteroaromatic groups in nonsteroidal antiinflammatory agents with the ferrocene group.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Blood Platelets; Female; Ferrous Compounds; Humans; Iron; Metallocenes; Organometallic Compounds; Platelet Aggregation; Rats; Rats, Inbred Strains; Serotonin; Structure-Activity Relationship

1983
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes.
    Molecular pharmacology, 1999, Volume: 55, Issue:5

    Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carrier Proteins; Oocytes; Xenopus laevis

1999
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.
    Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism

2005
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
    European journal of medicinal chemistry, 2012, Volume: 53

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Arachidonic acid metabolism in inflamed gingiva and its inhibition by anti-inflammatory drugs.
    Journal of periodontology, 1984, Volume: 55, Issue:9

    Topics: Anti-Inflammatory Agents; Arachidonic Acids; Flurbiprofen; Gingivitis; Humans; Periodontal Diseases; Prostaglandin Antagonists; Prostaglandins; Suprofen; Tolmetin

1984
Comparative efficacy of topically applied flurbiprofen, diclofenac, tolmetin, and suprofen for the treatment of experimentally induced blood-aqueous barrier disruption in dogs.
    American journal of veterinary research, 1996, Volume: 57, Issue:6

    Topics: Animals; Anterior Chamber; Anti-Inflammatory Agents, Non-Steroidal; Blood-Aqueous Barrier; Diclofenac; Dogs; Eye; Fluorescein; Fluoresceins; Fluorophotometry; Flurbiprofen; Ocular Physiological Phenomena; Ophthalmic Solutions; Random Allocation; Suprofen; Tolmetin

1996
Stereoselective inhibition of inducible cyclooxygenase by chiral nonsteroidal antiinflammatory drugs.
    Journal of clinical pharmacology, 1996, Volume: 36, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Flurbiprofen; Guinea Pigs; Humans; Isoenzymes; Ketoprofen; Ketorolac; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Sheep; Stereoisomerism; Tolmetin

1996
Serum protein binding of nonsteroidal antiinflammatory drugs: a comparative study.
    Journal of pharmacokinetics and biopharmaceutics, 1997, Volume: 25, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chromatography, High Pressure Liquid; Diclofenac; Female; Fenoprofen; Flurbiprofen; Humans; Ketoprofen; Male; Middle Aged; Naproxen; Protein Binding; Tolmetin

1997
Antinociceptive effects of S(+)-ketoprofen and other analgesic drugs in a rat model of pain induced by uric acid.
    Journal of clinical pharmacology, 1998, Volume: 38, Issue:S1

    Topics: Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Biotransformation; Disease Models, Animal; Dose-Response Relationship, Drug; Flurbiprofen; Injections, Intraventricular; Ketoprofen; Ketorolac; Male; Morphine; Pain; Rats; Rats, Sprague-Dawley; Rats, Wistar; Stereoisomerism; Tolmetin; Tromethamine; Uric Acid

1998
Inhibition of anandamide hydrolysis by the enantiomers of ibuprofen, ketorolac, and flurbiprofen.
    Archives of biochemistry and biophysics, 1999, Feb-15, Volume: 362, Issue:2

    Topics: Aging; Animals; Arachidonic Acids; Brain; Cell Extracts; Cell Survival; Dose-Response Relationship, Drug; Endocannabinoids; Flurbiprofen; Glioma; Hydrolysis; Ibuprofen; Inhibitory Concentration 50; Ketorolac; Kinetics; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Stereoisomerism; Time Factors; Tolmetin; Tumor Cells, Cultured

1999
Stereoselective and substrate-dependent inhibition of hepatic mitochondria beta-oxidation and oxidative phosphorylation by the non-steroidal anti-inflammatory drugs ibuprofen, flurbiprofen, and ketorolac.
    Biochemical pharmacology, 1999, Apr-01, Volume: 57, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Coenzyme A; Flurbiprofen; Ibuprofen; Ketorolac; Lipid Metabolism; Male; Mitochondria, Liver; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Palmitic Acid; Rats; Rats, Wistar; Stereoisomerism; Tolmetin

1999
Ionic liquid-based dynamic liquid-phase microextraction: application to the determination of anti-inflammatory drugs in urine samples.
    Journal of chromatography. A, 2008, Aug-15, Volume: 1202, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Fractionation; Flurbiprofen; Humans; Hydrogen-Ion Concentration; Indomethacin; Ionic Liquids; Ketoprofen; Molecular Structure; Naproxen; Phenylbutyrates; Reproducibility of Results; Tolmetin

2008
Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Anti-Inflammatory Agents, Non-Steroidal; Flufenamic Acid; Flurbiprofen; Hydroxyprostaglandin Dehydrogenases; Ibuprofen; Indomethacin; Meclofenamic Acid; Mefenamic Acid; Naproxen; Sulindac; Tolmetin

2012