tolfenamic-acid has been researched along with ethyl-cysteine* in 1 studies
1 other study(ies) available for tolfenamic-acid and ethyl-cysteine
| Article | Year |
|---|---|
Synthesis and pharmacological evaluation of amide conjugates of NSAIDs with L-cysteine ethyl ester, combining potent antiinflammatory and antioxidant properties with significantly reduced gastrointestinal toxicity.
The synthesis and pharmacological evaluation of a series of amide derivatives of NSAIDs with L-cysteine ethyl ester is described. The novel derivatives are potent antiinflammatory, antioxidant and hypocholesterolemic-hypolipidemic agents, while they demonstrate considerably reduced gastrointestinal toxicity. This molecular modification may offer a general route to safer antiinflammatory agents, potentially suitable for chronic use in conditions such as neurodegenerative disorders. Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cholesterol; Cysteine; Drug Evaluation; Gastrointestinal Diseases; Lipoproteins, LDL; Mice; Rats; Triglycerides | 2004 |